Negative / Null Result ReportOpen accessMedicine
Mkhize SF, Moodley J, Khaliq OP et al. · 2026 · South African family practice : official journal of the South African Academy of Family Practice/Primary Care
Background Pre-eclampsia (PE) is a major contributing factor to high rates of maternal and perinatal morbidity and mortality in South Africa. Early diagnosis is currently a challenge. The objective is to assess the diagnostic accuracy of…
View details →Negative / Null Result ReportMedicine
Ali M, Higginbotham A, Sabri E et al. · 2026 · Journal of obstetrics and gynaecology Canada : JOGC = Journal d'obstetrique et gynecologie du Canada : JOGC
Objectives Aspirin (ASA) is recommended for preeclampsia prophylaxis, but it is uncertain whether higher doses, such as the 150 mg/day used in the ASPRE trial, increase the risk of postpartum hemorrhage (PPH). In Canada, the available…
View details →Failed Experiment ReportMedicine
Özdemir E, Bilen Ç, Karakuş E · 2026 · Biotechnology letters.
In this study, medlar polyphenol oxidase (PPO) was partially purified by (NH₄)₂SO₄ precipitation and dialysis, respectively. The aim of the study was to investigate the inhibition effects of amino acids, which are candidate PPO ligands, on…
View details →Failed Experiment ReportOpen accessMedicine
Sangtani M, Mitra GV, Sangtani B et al. · 2026 · Bioinformation
Tooth extraction often results in trauma, leading to loss of alveolar bone and soft tissue. Therefore, it is of interest to compare the efficacy of physics forceps and conventional forceps in extracting non-carious and carious teeth. The…
View details →Negative / Null Result ReportOpen accessMedicine
Ji Z, Sun H, Jiang Y et al. · 2026 · BMC cancer
OBJECTIVE: To compare accuracy and efficacy between Image Navigation System (INS, an optical tracking system for real-time needle guidance) combined with 3D printing template (3DPT) versus 3DPT alone in radioactive I-125 seed brachytherapy…
View details →Negative / Null Result ReportOpen accessMedicine
Abd-Elfadiel Hagag OY, Ahmed-Helmy El-Rayes M, El-Hawy AS et al. · 2026 · Tropical animal health and production
This study evaluated the impact of incorporating varying levels of dried Azolla pinnata as a partial or full substitute for soybean meal protein on growth performance, productivity, and selected biochemical, immunological, hormonal, and…
View details →Negative / Null Result ReportMedicine
Meng D, Fan C, Dai Y et al. · 2026 · Shanghai kou qiang yi xue = Shanghai journal of stomatology
Purpose To observe the effect of different endpoints in chemical-mechanical caries removal for deep caries on the labial-buccal surface, and to provide reference for the selection of treatment methods and indications. Methods A total of 41…
View details →Negative / Null Result ReportOpen accessMedicine
Aslan S, Sozlu S, Bozkurt O et al. · 2026 · Journal of eating disorders
Aims Night eating syndrome (NES) is characterized by food consumption during bedtime or late night. This study aimed to evaluate the relationship between NES and resting metabolic rate (RMR), anthropometric measurements, and sleep quality.…
View details →Negative / Null Result ReportOpen accessMedicine
Xu S, Huang Z, Zou X et al. · 2026 · Journal of virus eradication
Background Elderly patients remain at high risk for adverse outcomes from COVID-19 despite the generally reduced pathogenicity of the Omicron variant. Corticosteroids are commonly used in hospitalized patients with COVID-19, particularly…
View details →Negative / Null Result ReportOpen accessMedicine
Scalia IG, Abdelfattah FE, Farina JM et al. · 2026 · Cardio-oncology (London, England)
BACKGROUND: Severe carcinoid heart disease (CaHD) may require bioprosthetic valve (BPV) replacement. Lutetium-177 (Lu-177) DOTATATE is increasingly utilized in patients with neuroendocrine tumors (NETs); however, its effect on BPVs remains…
View details →Negative / Null Result ReportOpen accessMedicine
Chantre-Justino M, Silvestre RT, Delmonico L et al. · 2026 · World journal of oncology
Background Bone sarcomas are rare and heterogeneous malignant neoplasms of mesenchymal origin, often associated with poor clinical outcomes. Being rare neoplasms, a comprehensive analysis of the molecular mechanisms involved in the tumor…
View details →Negative / Null Result ReportOpen accessMedicine
Akyuz C, Sunamak O, Selman A et al. · 2026 · Journal of clinical medicine
Background : Signet-ring cell colorectal cancer (SRCC) and colorectal cancer with a signet-ring cell component (SRC) are rare histological subtypes associated with poor prognosis. Although these entities are classified separately based on…
View details →Negative / Null Result ReportOpen accessMedicine
Fuchida H, Sawada D, Hirota T et al. · 2026 · Toxicology reports
Objective Lactobacillus gasseri CP2305 (L. gasseri CP2305) has been reported to exert intestinal regulatory, anti-stress, and sleep-improving effects in healthy adults. This study aimed to evaluate the safety of an excessive intake of L.…
View details →Negative / Null Result ReportMedicine
Alheany ARA, Abdulkareem AZ, Abdullah ZA et al. · 2026 · Asian Pacific journal of cancer prevention : APJCP
Background Hodgkin lymphoma (HL) arises from germinal center B cells through complex viral, genetic, and environmental factors. This study examines HHV-6B infection and the IL-18 rs1946518 polymorphism as potential contributors to…
View details →Negative / Null Result ReportMedicine
McCoy J, Gatt D, Shaw M et al. · 2026 · Pediatric pulmonology
Rationale Primary ciliary dyskinesia (PCD) is a phenotypically diverse disease; the impact of nutritional status on clinical trajectories in patients with PCD is not well defined. The aim of this study is to examine the impact of…
View details →Negative / Null Result ReportOpen accessMedicine
Liu J, Wu Y, Yang D et al. · 2026 · BMC medical imaging
BACKGROUND: Glomerulonephritis (GN) is a major contributor to chronic kidney disease, highlighting the need for reliable biomarker to monitor GN. This study aimed to evaluate the potential of diffusion kurtosis imaging (DKI) for dynamic…
View details →Negative / Null Result ReportMedicine
Ojinnaka GC, Okoye OI, Ojinnaka NC et al. · 2026 · Journal of tropical pediatrics
To compare the academic performance of urban primary school children with strabismus and/or amblyopia seen at the Eye Clinic of University of Nigeria Teaching Hospital (UNTH), Ituku-Ozalla, Enugu, Nigeria, with that of their controls. In…
View details →Negative / Null Result ReportMedicine
Ji RT, Xie XF, Jia ZY et al. · 2026 · Huan jing ke xue= Huanjing kexue
Cultivating salt-tolerant rice （STR） is an effective approach to ameliorating coastal saline soils （CSL）. In this study， the CSL without STR cultivation served as the control （CK）， while soils with different rice cultivation years （1-5…
View details →Negative / Null Result ReportOpen accessMedicine
Capraru TD, Bauer TC, Jordan P et al. · 2026 · Frontiers in aging neuroscience
Background Hepatitis E virus (HEV) exposure has been linked to neurologic manifestations and dementia. This study aims to clarify a possible association between HEV and Alzheimer's disease (AD). Methods We performed a single-center…
View details →Negative / Null Result ReportOpen accessMedicine
Peng H, Dong B, Naren G et al. · 2026 · Frontiers in microbiology
Introduction Grassland desertification substantially reduces soil organic carbon (SOC) stocks. However, the responses of two distinct SOC fractions-mineral-associated organic carbon (MAOC) and particulate organic carbon (POC)-to…
View details →Negative / Null Result ReportOpen accessMedicine
Albayrak B, Kader İT, Köroğlu EN et al. · 2026 · BMC oral health
BACKGROUND: The purpose of this in vitro study was to compare the distance and angular accuracy of current intraoral scanners and photogrammetry devices in a full-arch implant model. METHODS: Six multi-unit abutment replicas (Astra Tech…
View details →Negative / Null Result ReportOpen accessMedicine
Drews G, Migliorini F, Götze C et al. · 2026 · BMC musculoskeletal disorders
BACKGROUND: Sex-based analyses in total hip arthroplasty have become increasingly important in understanding the nuanced outcomes and risks associated with this surgical procedure. Recent studies analyzed the complex interplay between…
View details →Negative / Null Result ReportOpen accessMedicine
Ren S, Zhang L, Zhai Y et al. · 2026 · Journal of cardiovascular development and disease
Background Adults with congenital heart disease (CHD) are at markedly increased risk of infective endocarditis (IE); however, data comparing clinical characteristics and outcomes in surgically treated IE patients with and without CHD…
View details →Negative / Null Result ReportMedicine
Gezginci Akpinar E, Cabi Z · 2026 · Gastroenterology nursing : the official journal of the Society of Gastroenterology Nurses and Associates
The aim of this study was to evaluate the effect of virtual reality goggles on pain, anxiety, and comfort in patients undergoing non-sedated upper gastrointestinal tract endoscopy. This randomized controlled study was conducted with 60…
View details →Negative / Null Result ReportMedicine
Coppola G, Verna C, Michelotti A et al. · 2026 · American journal of orthodontics and dentofacial orthopedics : official publication of the American Association of Orthodontists, its constituent societies, and the American Board of Orthodontics
Background Although esthetic concerns are a primary motivation for seeking orthodontic treatment, few studies with strong protocols have evaluated its impact on facial and smile attractiveness as perceived by laypeople. This study aimed to…
View details →Negative / Null Result ReportOpen accessMedicine
Pisanò CA, Santino ML, Russotto A et al. · 2026 · iScience
Sleep disorders are common in Parkinson's disease (PD) and respond poorly to current pharmacological treatments, partly due to limited understanding of their underlying mechanisms. Using polysomnographic recordings, we investigated the…
View details →Negative / Null Result ReportMedicine
Duke DJ, Wang H, Rao L et al. · 2026 · International journal of pharmaceutics
Design of the mouthpiece of a pressurised metered dose inhaler is generally informed by patient needs, followed by manufacturing and product differentiation considerations. However, relatively few studies have investigated whether the size…
View details →Negative / Null Result ReportMedicine
Gonsalves V, Flake C, West D et al. · 2026 · Annals of dyslexia
Practitioner knowledge about dyslexia is related to improved educational practices, but few measures of dyslexia knowledge have been validated with rigorous processes. The current study developed the Dyslexia Assessment and Intervention…
View details →Failed Experiment ReportMedicine
Wang HK, Huang SH, Li CY et al. · 2026 · The journal of spinal cord medicine
Context/objective The optimal timing of surgical decompression for traumatic spinal cord injury (TSCI) remains uncertain. This study evaluated the association between ultra-early decompression and neurological outcomes, focusing on early…
View details →Negative / Null Result ReportMedicine
Dantagnan CA, Salem C, Charavet C et al. · 2026 · American journal of orthodontics and dentofacial orthopedics : official publication of the American Association of Orthodontists, its constituent societies, and the American Board of Orthodontics
Introduction This study aimed to compare the effect of artificial saliva (AS) aging on the trueness and precision of direct-printed aligners vs thermoformed aligners. Methods Four types of aligners were manufactured from the same reference…
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