12,382 real negative results, null findings, and replication failures in Medicine. Search the index →
WASTE indexes published research — it does not host or republish full papers. Each entry is a metadata record compiled from open scholarly databases; the abstract is shown in full only where the paper is openly licensed, otherwise a short excerpt under fair use. Classifications are automated and approximate.
Belmaker RH · 2025 · Pharmaceuticals (Basel, Switzerland)
Lithium was the first discovered mood stabilizer for bipolar disorder. However, several antiepileptics such as valproate and carbamazepine have also proven to be mood stabilizers in all phases of bipolar disorder with profiles barely…
View details →French B, Chiaro NVD, Holmes NP · 2022 · Experimental brain research
The grating orientation discrimination task (GOT) is a sensitive and reliable measure of tactile spatial resolution, or acuity. We used the GOT in three experiments to investigate the effects of hand posture and hand visibility on spatial…
View details →Johnson B, Addolorato G, Lesch O et al. · 2023 · Frontiers in psychiatry
A core principle in the pursuit of scientific knowledge is that science is self-correcting and that important results should be replicable. Hypotheses need to be reinforced, adjusted, or rejected when novel results are obtained.…
View details →Ferhatlar ME, Cumhur BA, Koca Y et al. · 2026 · European journal of trauma and emergency surgery : official publication of the European Trauma Society
Purpose The aim of this study is to prospectively compare the diagnostic performance of the PECARN, CATCH, and CHALICE clinical decision rules in pediatric patients presenting with minor head trauma, within a rural secondary-level…
View details →Zarghami Y, Rad MG, Mafeld S et al. · 2026 · Scientific reports
Continual automated pain detection from facial expressions using computer vision during procedural sedation could optimize sedation dose titration and minimize pain. A prospective observational study was conducted. Participants' faces were…
View details →Balraam Kv V, Nayak AR, Dass J et al. · 2026 · Journal of pediatric hematology/oncology
Background Systemic mastocytosis (SM) with associated acute myeloid leukemia (AML) is a rare malignancy usually linked to KIT p.D816V mutations. Observations We report a 17-year-old female with RUNX1::RUNX1T1-positive AML and florid mast…
View details →Slis A, Parrell B · 2026 · Journal of cognitive neuroscience
Sensory errors, mismatches between predicted sensory outcomes of movement and reafferent sensory feedback, drive changes in the feedforward control of future motor behavior that correct for those errors. Across a wide variety of motor…
View details →Kaiser A, Resasco J, Dee LE · 2026 · Nature ecology & evolution
Urban environments pose unique challenges for understanding drivers of biodiversity change, as fragmented land ownership makes traditional biodiversity monitoring and randomized experiments logistically difficult. While participatory…
View details →Swanstein HKJ, Gommeren K, Langhorn R et al. · 2026 · Journal of veterinary emergency and critical care (San Antonio, Tex. : 2001)
Objective To describe point-of-care ultrasound (POCUS) and clinical findings in cats with high-rise syndrome. Design Retrospective descriptive study. Setting University hospital. Animals Fourteen cats that fell from a height. Measurements…
View details →Romano F, Overbey K, Durocher-Jean A et al. · 2026 · Ophthalmic surgery, lasers & imaging retina
Background and objective This study describes a novel hyperspectral imaging (HSI) approach for visualizing and measuring geographic atrophy (GA) lesions in age-related macular degeneration. Patients and methods This cross-sectional…
View details →Akinci D'Antonoli T, Adams LC, Lübberstedt J et al. · 2026 · European radiology
Objectives To evaluate whether GPT-4.1 and Llama 3.3 70B, large language models (LLMs) assessed in zero-shot, baseline configurations, detect and categorize clinically consequential errors across types that range from pattern-based to…
View details →Hasan D, Sauer J, Heller C et al. · 2026 · Clinical neuroradiology
Purpose Hemorrhagic transformation (HT) within ischemic infarcts is a critical post-stroke complication that significantly influences secondary prevention strategies, particularly the timing and safety of anticoagulation. Ultra-low field…
View details →Theingi M, Ruengdit C, Punyamung M et al. · 2026 · Laboratory medicine
Introduction This study aimed to characterize the molecular and hematologic features of hemoglobin (Hb) Hekinan II in northern Thailand and to evaluate its phenotypic expression when co-inherited with other hemoglobinopathies. Methods In…
View details →Genç S, Uzun AN, Tanriverdi̇ H · 2026 · Folia microbiologica
Carbapenem resistance in Klebsiella pneumoniae is primarily mediated by carbapenemase production. This study aimed to identify carbapenemase genes in carbapenem-resistant K. pneumoniae isolates using multiplex polymerase chain reaction…
View details →Kim H, Yu H, Kim AR et al. · 2026 · Scientific reports
Retrospective dosimetry based on thermoluminescence (TL) and optically stimulated luminescence (OSL) using personal belongings was applied to a series of small‑scale radiological accidents that occurred in South Korea between 2015 and…
View details →Vendredy L, De Winter V, Van Lent J et al. · 2025 · The journal of gene medicine
Background Missense mutations in the HSPB8 gene, encoding the small heat shock protein B8, cause distal hereditary motor neuropathy (dHMN) or an axonal form of Charcot-Marie-Tooth disease (CMT subtype 2L). Mice expressing mutant Hspb8…
View details →Luedke SG, Lawrence TE, Lucherk LW et al. · 2026 · Journal of food protection
Foreign material contamination remains a leading source of consumer complaints in the meat industry, especially in the beef sector. Metallic foreign objects may enter carcasses during upstream animal handling or during processing, creating…
View details →Zeldenrust EG, Carlton K, Jenkins EJ et al. · 2026 · Veterinary parasitology
Klossiella equi Baumann, 1946 (Apicomplexa: Coccidia) is a globally distributed adeleorinid parasite that infects the kidneys of equid hosts. Considered an uncommon parasite, when K. equi is detected, it is typically an incidental finding…
View details →· 2006
Because of the low reported levels of progesterone in breastmilk, even with the high-dose products, amounts ingested by the infant are small and would not be expected to cause any adverse effects in breastfed infants. The progesterone…
View details →Shyam Kumar R, Chakraborty S, Jayakumar H et al. · 2026 · Molecular biology reports
Background N6-methyladenosine (m6A) modification of mRNAs through METTL3 maintains homeostasis in many cell types. The mechanism by which METTL3 complexes together with reader proteins, especially the YTH domain-containing protein, governs…
View details →Li S, Lv C, Xie P et al. · 2026 · Clinical nuclear medicine
A 6-year-old boy presented with a 2-month history of fever of unknown origin. 18F-FDG PET/CT was performed to identify the potential source, revealing a solitary focus of abnormal radiotracer uptake in the left humerus. Bone marrow biopsy…
View details →Karimi E, Momeni Z, Nasiri V et al. · 2026 · Diagnostic microbiology and infectious disease
Blastocystis is a genetically diverse unicellular eukaryotic intestinal parasite with no gold-standard diagnostic method. This study, conducted in Iran, is the first to directly compare Sequence-Tagged Site (STS) PCR and restriction…
View details →Deng D, Shiotani H, Kawakami Y · 2025 · Journal of anatomy
Quantifying strain in the free Achilles tendon (AT F ) is essential for understanding its mechanical function, yet existing in vivo studies report inconsistent strain values, even under comparable loading. These discrepancies are partly…
View details →Lye G, Pollard RE, Hartman A et al. · 2026 · Veterinary radiology & ultrasound : the official journal of the American College of Veterinary Radiology and the International Veterinary Radiology Association
The intrathoracic lymph nodes (LN) of clinical interest in dogs are the sternal (STLN), cranial mediastinal (CrMLN), and tracheobronchial (TBLN) groups. Although computed tomography (CT) depicts and measures these nodes well, thoracic…
View details →Hashimoto R, Otsuki Y, Nakamura T · 2026 · Cureus
Pulmonary metastases from papillary thyroid carcinoma (PTC) are usually detectable by computed tomography (CT) or radioactive iodine (RAI) scanning. Pathologically proven pulmonary micrometastases that are completely undetectable by…
View details →Khin STMM, Jafar SM, Ju M et al. · 2025 · Journal of virological methods
Feline morbillivirus (FeMV) is a globally emerging virus that has been linked to chronic kidney disease (CKD) in infected cats. Immunological assays, such as enzyme-linked immunosorbent assay (ELISA), are important for studying the virus…
View details →Lowe BG, Woolgar A, Smit S et al. · 2026 · Cortex; a journal devoted to the study of the nervous system and behavior
Sustaining attention is effortful but crucial for daily life. Despite this, attentional lapses are common and can have fatal consequences (e.g., when driving). The spontaneous nature of these lapses makes studying their underlying…
View details →Klement RJ, Sweeney RA · 2026 · Strahlentherapie und Onkologie : Organ der Deutschen Rontgengesellschaft ... [et al]
Purpose Ketogenic diets (KDs) have been proposed to target glycolytic cancer metabolism and synergize with radio- and chemotherapy. We herein report survival outcomes of rectal and head and neck cancer (HNC) patients who followed a KD…
View details →Peirano G, Walker SD, Duong MS et al. · 2026 · European journal of clinical microbiology & infectious diseases : official publication of the European Society of Clinical Microbiology
Introduction Metallo-β-lactamase (MBL)-producing Enterobacterales are increasing in frequency and treatment options are limited. Aztreonam/avibactam (AZA) and aztreonam (ATM) plus ceftazidime/avibactam (CZA) showed activities against these…
View details →Hayashi T, Mizobuchi K, Higa N et al. · 2026 · Ophthalmic genetics
Purpose To assess the detectability of the pathogenic RP1 Alu insertion using the PrismGuide™ inherited retinal dystrophy (IRD) panel, which targets 82 IRD genes, and whole-exome sequencing (WES). Methods A girl diagnosed with early-onset…
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