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Browse the failure-mode index

12,264 real negative results, null findings, and replication failures in Medicine. Search the index →

WASTE indexes published research — it does not host or republish full papers. Each entry is a metadata record compiled from open scholarly databases; the abstract is shown in full only where the paper is openly licensed, otherwise a short excerpt under fair use. Classifications are automated and approximate.

Negative / Null Result ReportMedicine

Interpersonal Relationship, Academic Performance, & Life Skills: A Comparative Study of Children With and Without Emotional and Behavioral Problems.

Kheto P, Pallerla S, Bhattacharjee K et al. · 2026 · Clinical child psychology and psychiatry

BackgroundEmotional and behavioral problems (EBPs) in children significantly influence developmental domains, including interpersonal relationships, academic performance, and life skills.MethodsA cross-sectional study was adopted with…

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Negative / Null Result ReportMedicine

Comparing Self-Reports, Pill Counts, and Electronic Devices in Assessing ART Adherence and its Association with Viral Suppression in Adolescents Living with HIV.

Kizito S, Ssewamala FM, Nabayinda J et al. · 2026 · Journal of acquired immune deficiency syndromes (1999)

Background We compared the performance of self-reports, pill counts, and electronic adherence measures in monitoring antiretroviral therapy (ART) adherence and association with viral suppression among adolescents living with HIV (ALHIV).…

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Negative / Null Result ReportMedicine

Vertical Maxillary Movement Is Associated With Incisal Display in Orthognathic Surgery.

Han MD, Shimchuk A, Dosoudil E et al. · 2026 · Journal of oral and maxillofacial surgery : official journal of the American Association of Oral and Maxillofacial Surgeons

Background Maxillary incisal display (MID) is a key feature in orthodontic and orthognathic surgical planning that critically impacts esthetics and forms the basis for the vertical positioning of the maxilla. In orthognathic surgical…

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Negative / Null Result ReportMedicine

Impact of emergency medical services volume on outcomes and management in prehospital traumatic cardiac arrest: a retrospective cohort study.

Morcel B, Yordanov Y, Mercier E et al. · 2026 · Scandinavian journal of trauma, resuscitation and emergency medicine

Background While volume-outcome relationships for non-traumatic out-of-hospital cardiac arrest have been reported in hospital settings, the impact of prehospital exposure, particularly for the rare and clinically complex entity of…

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Negative / Null Result ReportOpen accessMedicine

Postoperative Consequences of Fear and Anxiety in Open Heart Surgery: A Comparative Analysis of Two Patient Groups.

Dizdar E, Kiliç A, Alkan Kayhan S et al. · 2026 · The journal of nursing research : JNR

Background Patients undergoing open heart surgery may experience negative emotions such as anxiety, fear, panic, and anger in the preoperative period that may negatively affect their postoperative recovery. Purpose This study was designed…

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Negative / Null Result ReportOpen accessMedicine

COVID-19 vaccination remains essential for healthcare professionals: clinical evidence from a Polish cross-sectional study.

Hoffmann K, Michalak M, Jarząb M et al. · 2026 · Frontiers in public health

Introduction Six years after the emergence of SARS-CoV-2, vaccination remains still central to preventing severe COVID-19. The aim was to determine the impact of the vaccine type and number of doses on the course of COVID-19 infection…

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Negative / Null Result ReportMedicine

Associations of 2000 m Rowing Ergometer Performance With Load-Velocity Relationship Variables Obtained During Bilateral and Unilateral Prone Bench Pull and Leg Press.

Pérez-Castilla A, Quidel-Catrilelbún MEL, Baena-Raya A et al. · 2026 · Journal of strength and conditioning research

Abstract Pérez-Castilla, A, Quidel-Catrilelbún, MEL, Baena-Raya, A, Miras-Moreno, S, Conceição, F, Fernandes, JFT, and Ramirez-Campillo, R. Associations of 2000 m rowing ergometer performance with load-velocity relationship variables…

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Failed Experiment ReportOpen accessMedicine

The impact of infertility-related stress, physiological stress and some fertility indices on clinical pregnancy in women undergoing in vitro fertilization.

Omidifar N, Najafi E, Nasiri K et al. · 2025 · BMC pregnancy and childbirth

BACKGROUND: Despite numerous studies on the impact of stress on post-in vitro fertilization (IVF) clinical outcomes are contradictory and researchers recommend the need for further studies. Therefore, the purpose of the present study was…

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Negative / Null Result ReportMedicine

The Elevated Eosinophil Counts and Neutrophils/Lymphocytes Ratio as Predicting Biomarkers in Non-responders, Chronic Spontaneous Urticarial Patients to Cetirizine/Famotidine Treatment.

Khalili A, Estakhri Z, Shams A et al. · 2026 · Iranian journal of allergy, asthma, and immunology

The responses of patients with chronic spontaneous urticaria (CSU) to regular therapeutic options vary. While these methods are effective for some patients, many do not respond successfully. Despite several studies conducted to identify…

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Negative / Null Result ReportOpen accessMedicine

The relationship between compassion fatigue and perceptions of spirituality and spiritual care in intensive care unit nurses: a cross-sectional study.

Neşe A, Yiğit B, Bakır E · 2026 · BMC nursing

BACKGROUND: Intensive care units (ICUs) are high-stress environments that significantly predispose nurses to compassion fatigue, affecting both their well-being and the quality of patient care. Spirituality and spiritual care are often…

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Negative / Null Result ReportOpen accessMedicine

Relationship of vitamin D receptor expression with hormone receptors and other clinicopathological features in primary breast carcinomas: A retrospective cross-sectional study.

Ünlü Y, Ömeroğlu E, Ay AS et al. · 2025 · Medicine

Breast cancer is a heterogeneous disease in which estrogen receptor (ER), progesterone receptor (PR), human epidermal growth factor receptor 2 (HER2), and Ki-67 play crucial roles in molecular subtyping, diagnosis, treatment, and…

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Negative / Null Result ReportMedicine

Incidence of thromboembolic events in testicular cancer patients receiving cisplatin (TESTCIS study).

Dubois M, Joly M, Dionne A et al. · 2026 · Journal of oncology pharmacy practice : official publication of the International Society of Oncology Pharmacy Practitioners

IntroductionDespite the increased incidence of testicular cancer in men aged 15 to 35, patients with this neoplasm have a high five-year survival rate thanks to chemotherapy. However, cisplatin, a drug used in the standard treatment for…

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Negative / Null Result ReportMedicine

The relationship between individual characteristics and musculoskeletal disorders in tuna fishermen in Pelita Jaya Hamlet, West Seram Regency, in 2024.

Mailuhu JT, Silalahi PY, Maruanaya S et al. · 2025 · International maritime health

Background Indonesia is a country with vast marine areas. It is also part of the world's coral reef triangle, which means that Indonesia has various types of coral reef species. This gives Indonesia a very strong maritime potential.…

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Negative / Null Result ReportMedicine

A microplastic meal: A baseline assessment of microplastic polymer presence within manta-ray (Mobula alfredi) feeding grounds at D'Arros Island and the St. Joseph Atoll.

Choppy MT, Duncan MI, Gordon N et al. · 2026 · Marine pollution bulletin

Microplastic ingestion by reef manta rays (Mobula alfredi) is a threat to their health and population stability. Seychelles' outer islands are vital habitats for M. alfredi but nothing is known about marine microplastic pollution in the…

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Negative / Null Result ReportMedicine

The effect of physiological changes in estradiol hormone during the follicular phase of the menstrual cycle in healthy women on retinal ganglion cell function, retinal and optic nerve vascularization and structure.

Hamurcu M, Gültekin BP, Göçmen M et al. · 2026 · Documenta ophthalmologica. Advances in ophthalmology

Purpose This study aimed to investigate the effects of estradiol changes occurring during the early follicular phase of the menstrual cycle on retinal ganglion cell function, retinal and optic nerve vascularity and structure in healthy…

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Negative / Null Result ReportMedicine

No Association Between Anatomic Factors and Non-Contact ACL Injury Risk in 217 Female Team Sport Players: A Prospective 4.5-Year Study.

Leppänen M, Jarske H, Krosshaug T et al. · 2026 · Scandinavian journal of medicine & science in sports

The purpose of this explorative study was to investigate the association between anatomic factors and risk for non-contact anterior cruciate ligament (ACL) injuries among female team sport players. A total of 225 players from basketball,…

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Negative / Null Result ReportMedicine

Visual Outcomes and the Impact of Intermediate Segment Orientation on the Performance of an Asymmetric Multifocal Intraocular Lens.

McLintock C, Uprety S, McKelvie J et al. · 2026 · Journal of refractive surgery (Thorofare, N.J. : 1995)

Purpose To evaluate the visual outcomes and the impact of intermediate segment orientation on the performance of an asymmetric multifocal intraocular lens (IOL) in patients who have cataract. Methods In this retrospective single-center…

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Negative / Null Result ReportMedicine

Understanding AI adoption in medical education: Insights from students and faculty members in Indonesian medical schools.

Rujito L, Muhaimin A, Pergodi MA et al. · 2026 · Journal of education and health promotion

Background Artificial Intelligence (AI) implementation in medical education has changed the learning process, with new forms of diagnosis, treatment planning, and patient care. Biases in AI adoption among Indonesian medical schools'…

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