e-ISSN: Pending
Replication FailureMedicine

Association Between FTO rs1558902 Polymorphism, Age-Related Hypogonadism, and Central Obesity in Japanese Men.

Tsutsumi T; Okuma H; Kazama F; Endo M; Takato Y; Nara H; Miyazaki A; Harai N · 2026 · Andrology

WASTE classifies this as Replication Failure · AI classification, approximate

A previously reported effect did not replicate here — verify it holds before you build on it.

Abstract (excerpt)

Background Obesity and low testosterone levels are closely interconnected, with the FTO gene being the most robust genetic determinant of body mass index (BMI). However, whether this primary genetic driver of obesity directly influences…

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Metadata source: Europe PMC · DOI 10.1111/andr.70261