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WASTE Journal

Browse the failure-mode index

12,264 real negative results, null findings, and replication failures in Medicine. Search the index →

WASTE indexes published research — it does not host or republish full papers. Each entry is a metadata record compiled from open scholarly databases; the abstract is shown in full only where the paper is openly licensed, otherwise a short excerpt under fair use. Classifications are automated and approximate.

Negative / Null Result ReportMedicine

Myocardial expression of <i>ADGRL4</i> and <i>AQP7</i> is related to regression of left ventricular hypertrophy after aortic valve replacement in a sex-dependent manner.

Halldórsson KB, Karagianni K, Leite-Moreira AF et al. · 2026 · American journal of physiology. Heart and circulatory physiology

Aortic stenosis (AS) may lead to left ventricular (LV) hypertrophy (LVH). After aortic valve replacement (AVR), LVH often does not regress fully. This has been associated with a worse prognosis. This study aimed at comparing LVH regression…

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Negative / Null Result ReportOpen accessMedicine

Migraine as an occupational health risk among nurses in Qassim region, Saudi Arabia: a multicenter study of risk perceptions and associated factors.

Qalawa SAA, Elbqry MG, Elmansy FM et al. · 2026 · Frontiers in public health

Background Migraine is a common neurological disorder and an emerging occupational health risk among nurses due to demanding workloads, shift work, workplace stress, and prolonged screen exposure. Understanding nurses' risk perceptions of…

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Negative / Null Result ReportOpen accessMedicine

The Relationship between Perceived Food Environment and Glycemic Control Among Malaysian Diabetic Patients.

Berahim AS, Rohana AJ, Yaacob NM et al. · 2026 · International journal of preventive medicine

Background The perceptions of diabetic patients on their food environment influence their dietary choices and would impact glycemic control. The main aim of this study was to determine any relationship between perceived food environment…

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Negative / Null Result ReportMedicine

Interspecific patterns of variation in dental growth increments of crocodilians.

Hogg R · 2026 · Developmental dynamics : an official publication of the American Association of Anatomists

Background Multiple studies have supported the hypothesis that incremental growth lines in crocodilian dentin are analogous with circadian von Ebner's lines in mammals; however, variation in these growth lines has been largely unstudied.…

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Negative / Null Result ReportMedicine

A 10-Year Retrospective Cohort Study of Stevens-Johnson Syndrome and Toxic Epidermal Necrolysis at the Royal Brisbane and Women's Hospital.

Pagliaro T, Butler G, Godbolt A et al. · 2026 · The Australasian journal of dermatology

Background/objectives The Royal Brisbane & Women's Hospital (RBWH) in Queensland, Australia provides definitive care for all diagnosed adult patients with SJS/TEN within its catchment. In this retrospective cohort study, we identified all…

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Negative / Null Result ReportOpen accessMedicine

A scoping review of mystical-type experiences and mood symptom outcomes in psychedelic therapy clinical trials: comparing life-threatening disease and depressive populations.

Deutsch A, Contreras LE, Kratina S et al. · 2026 · Therapeutic advances in psychopharmacology

Background Psychedelic therapies are gaining attention as tools to alleviate anxiety and depression across various clinical populations. However, the mechanisms behind psychedelics' therapeutic efficacy and the potential differences in how…

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Negative / Null Result ReportOpen accessMedicine

The relationship between diet quality index (DQI) with inflammatory indices and body mass index (BMI) in inflammatory bowel disease (IBD) patients.

Karimi P, Ramezani E, Daryani NE et al. · 2025 · Scientific reports

Background Inflammatory bowel disease (IBD) is a complex and chronic condition of the gastrointestinal tract. Diet is a significant factor influencing the onset and course of IBD. The Diet Quality Index (DQI) is an essential tool for…

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Negative / Null Result ReportMedicine

Physical Activity and Exergame Interest Among Adolescents with Probable Developmental Coordination Disorder: Potential to Shift Toward Active Play.

Temlali TY, Lust JM, Valtr L et al. · 2026 · Physical & occupational therapy in pediatrics

Aims This study examined physical activity levels, video gaming habits, and interest in using exergames among adolescents with probable developmental coordination disorder (p-DCD). It also explored relationships between physical activity,…

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Negative / Null Result ReportMedicine

Cloning-based analysis of MHC class II DRB variation and Enterocytozoon bieneusi association in the Amur tiger (Panthera tigris altaica).

Liu Y, Xu H, Zhang Y et al. · 2026 · Molecular and biochemical parasitology

The polymorphism of major histocompatibility complex (MHC) class II classical genes is closely related to pathogen resistance, among which the second exon of the DRB gene has the highest variability. In this study, we analyzed exon 2 of…

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Negative / Null Result ReportOpen accessMedicine

Real-Time Prediction of Irreversible Lesion Size During Pulsed Field Ablation: Prospective Validation of a Novel Ablation Index Based on Contact Force and Number of Applications in a Swine Beating Heart Model.

Nakagawa H, Farshchi-Heydari S, Sugawara M et al. · 2025 · Circulation. Arrhythmia and electrophysiology

Background In a previous study, on pulsed-field ablation (PFA) in the swine ventricle, we found that lesion depth was described (±1 mm accuracy) by a logarithmic function of contact force (CF) and the number of PFA pulses (PF-ablation…

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Negative / Null Result ReportMedicine

Length of maxillomandibular discrepancy may not predict tongue base airway obstruction severity among infants with Robin Sequence.

Bryton CA, Tingen JN, Scott AR · 2026 · International journal of pediatric otorhinolaryngology

Objective To evaluate the relationship between severity of micrognathia and mandibular distraction distance required to alleviate symptoms among neonates with isolated Robin Sequence (iRS), as measured by frontal nasomental (FNM) angle…

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Negative / Null Result ReportMedicine

An Examination of Buprenorphine and Norbuprenorphine Concentrations in Inpatients Receiving Medications for Opioid Use Disorder.

Haykal M, Li B, Avellaneda Ojeda A et al. · 2026 · The journal of applied laboratory medicine

Background Interpretation of urine buprenorphine and norbuprenorphine concentrations is widely used to assess adherence during treatment for opioid use disorder. However, the relationships between dose, timing of sample collection, and…

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Negative / Null Result ReportOpen accessMedicine

Per- and polyfluoroalkyl substances (PFAS) and heavy metals in the egg of peregrine falcon (Falco peregrinus) populations in West England, United Kingdom.

Ozaki S, Chaplow JS, Dodd B et al. · 2026 · Ecotoxicology (London, England)

This study focused on the exposure of a terrestrial raptor, the peregrine falcon (Falco peregrinus), in the United Kingdom. In contrast to inland areas, peregrine falcons in coastal areas of North Cornwall, South-west England, have…

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