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Browse the failure-mode index

12,264 real negative results, null findings, and replication failures in Medicine. Search the index →

WASTE indexes published research — it does not host or republish full papers. Each entry is a metadata record compiled from open scholarly databases; the abstract is shown in full only where the paper is openly licensed, otherwise a short excerpt under fair use. Classifications are automated and approximate.

Negative / Null Result ReportMedicine

[Exploration of the value of VAS score in the diagnosis and treatment of patients with vestibular diseases during caloric test].

Tian L, Liu X, Yu J et al. · 2026 · Lin chuang er bi yan hou tou jing wai ke za zhi = Journal of clinical otorhinolaryngology head and neck surgery

Objective: To identify the factors influencing the visual analogue scale(VAS) scores for distress experienced by patients with vestibular diseases during caloric tests, and to explore the value of VAS scores in disease diagnosis and…

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Negative / Null Result ReportMedicine

Echolocating free-tailed bats use vision and hearing but not magnetoreception when navigating a maze.

Lemus K, Meyers R, Ellis S et al. · 2026 · Journal of comparative physiology. A, Neuroethology, sensory, neural, and behavioral physiology

Insectivorous bats navigate mainly by echolocation, but may also use visual, olfactory, and magnetic cues when travelling long distances. Parsing the relative contributions of different senses for navigation is difficult in wild bats. In…

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Negative / Null Result ReportMedicine

Ultrasonographic optic nerve sheath diameter for predicting elevated intracranial pressure and clinical severity in children: a prospective observational study.

Naseem M, Anand V, Das R et al. · 2026 · European journal of pediatrics

Elevated intracranial pressure (ICP) can complicate various neurological conditions in children and may result in fatal brainstem herniation. Early detection and management can prevent this fatal complication. This prospective…

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Negative / Null Result ReportMedicine

Dysregulation of HIF-1α-regulated and thromboinflammatory genes may contribute to thrombotic risk in patients with BCR::ABL1-negative myeloproliferative neoplasms.

Morath O, Wolfrum T, Crodel C et al. · 2026 · Journal of thrombosis and haemostasis : JTH

Background Hypoxia-inducible factor-1α (HIF-1α) regulates multiple pathways involved in metabolism, inflammation, and coagulation and may contribute to thrombotic complications in patients with BCR::ABL1-negative myeloproliferative…

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Negative / Null Result ReportMedicine

Persistent Chemotherapy-Induced Alopecia: Updates in Diagnosis and Treatment Persistent Chemotherapy Induced Alopecia: An Updated Approach.

Garza-Rodríguez V, Imbernon-Moya A, Hermosa-Gelbard A et al. · 2026 · Actas dermo-sifiliograficas

Chemotherapy-induced alopecia (CIA) is characterized by absent or incomplete hair regrowth after completion of chemotherapy. Alopecia that persists beyond 6 months after completing chemotherapy is defined as persistent chemotherapy-induced…

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Negative / Null Result ReportMedicine

Autopolyploidy exacerbates dominance masking under negative frequency-dependent selection: evidence from sporophytic self-incompatibility in Arabidopsis arenosa and Arabidopsis lyrata.

Vekemans X, Kolesnikova U, Vlček J et al. · 2026 · Philosophical transactions of the Royal Society of London. Series B, Biological sciences

Polyploidy is widespread within flowering plants, with 35% of extant species being recent polyploids. Whether and how polyploidy modulates the action of natural selection remains debated, and the particular case of balancing selection has…

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Negative / Null Result ReportMedicine

Asthma in Active Military Aircrew: Long-term Health and Flight Performance.

Angel O, Rittblat M, Freund O et al. · 2026 · The Israel Medical Association journal : IMAJ

Background Asthma poses unique challenges in aviation medicine. While strict criteria typically dictate waiver approvals in military aviators with asthma, the Israeli Air Force (IAF) applies a more individualized approach. Still, evidence…

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Negative / Null Result ReportMedicine

Combined Hormonal Contraception with Low-Dose Ethinylestradiol is Associated with Modest Reduction of Breast Milk Volume when Administered Vaginally, but Not Orally.

Segev L, Weitzman G, Hijazi B et al. · 2026 · Breastfeeding medicine : the official journal of the Academy of Breastfeeding Medicine

Background Combined hormonal contraception (CHC) is habitually not prescribed to breastfeeding women due to concerns of decreased milk production. This habit is based on inconclusive studies that examined lactation suppression of CHC with…

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Negative / Null Result ReportMedicine

Biomechanical assessment of intraocular lens stability and position based on suture and inlet variations in the Canabrava double-flanged technique.

Suh YK, Choi S, Yoon CK et al. · 2026 · Journal of cataract and refractive surgery

Purpose To evaluate how variations in suture type, suture length, and scleral outlet angle affect intraocular lens (IOL) positioning and fixation stability in the Canabrava technique, given ongoing concerns such as iris chafing and the…

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Negative / Null Result ReportMedicine

Differences in Cyclotorsion Compensation Between Low, Medium, and Large Angles in Myopic PRK: Visual and Refractive Results.

Ben Ephraim Noyman D, Safir M, Sommer A et al. · 2026 · Journal of refractive surgery (Thorofare, N.J. : 1995)

Purpose To evaluate the differences in myopic photorefractive keratectomy (PRK) outcomes between small, medium, and large cyclorotational angle degrees. Methods This retrospective comparative study was conducted at Care Vision Laser…

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Negative / Null Result ReportMedicine

Accuracy of Continuous Glucose Monitoring in Adults With Postbariatric Hypoglycemia After Roux-en-Y Gastric Bypass Surgery Under Stable and Dynamic Glucose Conditions.

Lizoain A, Vettoretti M, Ferreira A et al. · 2026 · Diabetes care

Objective Although continuous glucose monitors (CGMs) are increasingly used to detect and manage postbariatric hypoglycemia (PBH) and associated glucose variability, data on their accuracy in this population remain scarce. Research design…

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Negative / Null Result ReportMedicine

[Survey on the establishment of smoking areas in city halls in National Association of Directors of Health Departments of Designated Cities, West Block Conference].

Hamada M, Miyamura K, Kasamatsu M et al. · 2026 · [Nihon koshu eisei zasshi] Japanese journal of public health

Objectives In Tokyo, preventing passive smoking progressed during the 32nd Olympic Games. However, smoking areas remain in many local city halls, and tobacco product companies donate smoking areas in front of stations and near parks. A…

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Negative / Null Result ReportOpen accessMedicine

Relationships Among Cognitive Distortions, Forgiveness of Others, and Self-Forgiveness in Psychiatric Outpatients with Depressive Disorders: A Cross-Sectional Study.

Saklamaz S, Akpınar H · 2026 · Healthcare (Basel, Switzerland)

Background : Depression is associated with cognitive, emotional, and interpersonal difficulties that may influence forgiveness-related processes. This study aimed to examine the relationships among cognitive distortions, forgiveness of…

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Negative / Null Result ReportMedicine

An examination of core beliefs in generalized anxiety disorder.

Doust AE, Trenoska Basile V, McDonald S et al. · 2026 · The British journal of clinical psychology

Objective Generalised anxiety disorder (GAD) is characterised by uncontrollable worries. Cognitive behaviour therapy (CBT) is an effective treatment for GAD; however, manualised treatments rarely include interventions to target core…

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