12,264 real negative results, null findings, and replication failures in Medicine. Search the index →
WASTE indexes published research — it does not host or republish full papers. Each entry is a metadata record compiled from open scholarly databases; the abstract is shown in full only where the paper is openly licensed, otherwise a short excerpt under fair use. Classifications are automated and approximate.
Sadic AK, Susgun S, Alkhalidi D et al. · 2026 · Nutrition and health
BackgroundAspartame, a widely used artificial sweetener, is metabolized into phenylalanine, aspartic acid, and methanol. Previous studies have suggested that these metabolites may exert detrimental effects on the human body, particularly…
View details →Huang CT, Wen YT, Liu PK et al. · 2026 · QJM : monthly journal of the Association of Physicians
Background Indirect traumatic optic neuropathy (TON) is associated with severe vision loss and no proven treatment. Aim To evaluate the safety and exploratory functional outcomes of intravitreal pegfilgrastim in patients with indirect TON.…
View details →Hodgson NA, Latif S, Talwar S et al. · 2026 · Journal of the American Geriatrics Society
Background The Alzheimer's Association partnered with health systems in Illinois, Greater Missouri, and Washington to implement and evaluate the Knight Family dementia care coordination (DCC) program, a novel telephone-based care…
View details →Deniz B, Arpaci MF, Pekmez H et al. · 2026 · Journal of neuro-oncology
Purpose Brain tumors, characterized by the uncontrolled proliferation of abnormal cells within cerebral tissue, remain clinically challenging entities. Radiotherapy and chemotherapy constitute fundamental therapeutic modalities; however,…
View details →Virupakshaiah A, Gill AJ, Schoeps VA et al. · 2026 · Brain and behavior
Purpose/introduction The anti-JC virus (JCV) antibody index is used to stratify the risk of progressive multifocal leukoencephalopathy (PML) in multiple sclerosis (MS), particularly with natalizumab therapy. B-cell-depleting therapies may…
View details →Sen E, Aytekin A · 2026 · Revista da Associacao Medica Brasileira (1992)
Objective Thiol-disulfide homeostasis is a marker of oxidative stress. The aim of the study was to compare the effects of low-flow desflurane and sevoflurane anesthesia on perioperative changes in thiol-disulfide balance in patients…
View details →Sinha R, Singh R, Tripathi M et al. · 2025 · Indian journal of ophthalmology
Purpose To study the change in the vault of phakic Intraocular Lens (IOL) (pIOL) with RT view anterior segment optical coherence tomography (ASOCT) in different light conditions and define its relationship with the change in pupillary…
View details →Bachelard L, Blanc N, Michel A · 2026 · BMJ supportive & palliative care
Objective Breast cancer surgery often leads to a high burden of distressing symptoms, underscoring the need for supportive care to help patients throughout the perioperative period. This pilot study aimed to evaluate the feasibility,…
View details →Mosch B, Diers M · 2026 · Pain reports
Introduction Since the outbreak of COVID-19, many studies have investigated long-term consequences associated to the pandemic. Undoubtedly, restrictions and changes in everyday life during that time have had a broad impact on mental health…
View details →Achar A, Houser P, Cherian J et al. · 2026 · Lupus
ObjectiveTo determine the long-term outcomes of patients with moderate-severe pediatric systemic lupus erythematosus (pSLE) treated with systematic administration of combination rituximab (RTX) and cyclophosphamide (CYC) at our…
View details →Burger C, Pirotte M, Ray K et al. · 2026 · The western journal of emergency medicine
Introduction Emergency physicians commonly receive feedback in the form of performance metrics such as patients seen per hour. Reviewing metrics has been associated with increased stress and burnout. Although effects on efficiency have…
View details →Jang YE, Kim Y, Kim HI et al. · 2026 · Journal of endodontics
Introduction Hydraulic calcium silicate cement-based sealers (CSC sealers) are now frequently used with warm vertical compaction in root canal treatment. However, the impact of heat on the biological properties of CSC sealers remains…
View details →Nakano H, Shiinoki T · 2026 · Journal of neuro-oncology
PURPOSE: The radiosensitivity index (RSI) is a transcriptomic predictor of intrinsic radiosensitivity. The longitudinal behavior of the RSI in glioma and its variation across intratumoral cellular states have been unknown. We investigated…
View details →Chang TP, Kuo YH, Bery AK · 2026 · Frontiers in neurology
Background Dizziness is common in older adults, and often presents a diagnostic challenge. Vestibular function declines with age, but the prevalence and diagnostic explanatory value of mild vestibular loss in isolation (i.e., the clinical…
View details →Silva TR, Poínhos R, Oliveira BMPM et al. · 2026 · The British journal of nutrition
While rapid four-compartment (4C) models have demonstrated cross-sectional validity in diverse populations, including athletes, their longitudinal validity remains unverified. This study aims to evaluate the longitudinal validity of…
View details →Hugueny J, de Ricolfis A, Johnson N et al. · 2025 · Thrombosis research
Objective This review aimed to synthesize recent data on venous thromboembolism (VTE) risk in the context of masculinizing hormone therapy with testosterone. Methods An electronic search was performed in MEDLINE/PubMed without date…
View details →Rhodes J, Leach A · 2026 · Journal of sport & exercise psychology
Imagery is widely used in sport, but its effectiveness depends on how it is structured and the range of senses engaged. This study compared Functional Imagery Training-a multisensory, motivational intervention-with single-sense internal…
View details →Anthuparambil ND, Timmermann S, Dargasz M et al. · 2026 · The Journal of chemical physics
The effect of lowered pH on the thermal gelation behavior of hen egg yolk was investigated over the temperature range of 58-72 °C using low-dose X-ray photon correlation spectroscopy in ultra-small-angle X-ray scattering geometry.…
View details →Tikhonova P, Mekonnen Z, Belanger KD et al. · 2026 · Communications medicine
Background Mass deworming programs using anthelmintic drugs are a common public health strategy for controlling soil-transmitted helminth (STH) infections in high-risk, low-income countries. However, whether routine deworming induces…
View details →Ma CY, Chen J, Fu Y et al. · 2026 · BMC medical education
Background Competence in radiation oncology is still commonly expected to emerge through apprenticeship, although essential tasks such as target delineation, treatment-plan review, and multidisciplinary reasoning are not reliably sampled…
View details →Burnet G, Vasic I, Sauaia A et al. · 2026 · Journal of surgical education
Objective To determine the efficacy of cognitive behavioral therapy (CBT) on stress, anxiety, burnout, and depression in surgical interns and to determine the optimal timing of CBT. Our hypothesis was that CBT could improve each of these…
View details →Mehraj F, Bhat MA, Mangulkar A et al. · 2025 · Journal of pharmacy & bioallied sciences
Introduction In recent years, there has been a great deal of interest in research because of the changes that the extraction of premolars has caused to the structures surrounding of the upper airway. This is because it's thought that these…
View details →Benson JC, Carr CM, Mark IT et al. · 2026 · AJNR. American journal of neuroradiology
Background and purpose Wrong-site vertebroplasty is a known complication of image-guided procedures. Although rare, these errors have considerable clinical and medicolegal implications and are considered "never" events. This iterative…
View details →Rodriguez-Belenguer P, Beser-Robles M, Marfil-Trujillo M et al. · 2026 · Computer methods and programs in biomedicine
Background and objectives Radiomics-based machine learning models are increasingly used for clinical decision-making, yet their reliability is often constrained by limited sample sizes and class imbalance in imaging datasets. While prior…
View details →Denstad SE, Volløyhaug I, Lieng M et al. · 2026 · Journal of minimally invasive gynecology
Study objective To evaluate changes in health-related quality of life (HRQoL) 3 years after laparoscopic hysterectomy (LH) for benign, prophylactic, and malignant indications, and to identify baseline factors associated with these changes.…
View details →Yuan L, Li T, Jiang D et al. · 2026 · Insect science
A broad host range facilitates the rapid spread of Hyphantria cunea. This study explored the mechanism underlying the multi-host adaptability of H. cunea larvae, focusing on glutathione S-transferase (GST), and developed nucleic acid…
View details →Tan J, Rurak BK, Helmich RC et al. · 2026 · Clinical neurophysiology : official journal of the International Federation of Clinical Neurophysiology
Objective Tremor is a common motor symptom of Parkinson's disease (PD) that reduces quality of life. Cortico-cortical paired associative stimulation (ccPAS) is a transcranial magnetic stimulation protocol that induces connective…
View details →Bode-Akinboye E, Rietdijk R, Dale R et al. · 2026 · American journal of speech-language pathology
Purpose Adults with moderate-severe traumatic brain injury (TBI) often have significant communication challenges, particularly in interpersonal conversations. Most research aiming to understand these challenges has used static measures of…
View details →Acar GC, Tuncel S · 2026 · PeerJ
Background This study aims to investigate the effects of Zumba dance training conducted in a mirrored environment on participants' knee joint position sense (proprioception), static-dynamic balance and mood state. Methods A total of 39…
View details →Kucuk SD, Jabet P, Groso A et al. · 2026 · South African Journal of Botany.
Black rice (Oryza sativa L.) is a rich source of phenolics and flavonoids, making it a candidate ingredient for dermocosmetic applications. This study aimed to evaluate the bioactive potential of an ethanolic black rice extract as a…
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