12,263 real negative results, null findings, and replication failures in Medicine. Search the index →
WASTE indexes published research — it does not host or republish full papers. Each entry is a metadata record compiled from open scholarly databases; the abstract is shown in full only where the paper is openly licensed, otherwise a short excerpt under fair use. Classifications are automated and approximate.
Asfour H, Aram K, Hassouna M et al. · 2026 · Annals of surgical oncology
Background Skin grafting after skin cancer excision is a commonly performed procedure. Preoperative identification and optimization of patients at risk of graft failure can improve outcomes and healthcare cost effectiveness. This study…
View details →Soltani S, Rahimi HR, Seifi N et al. · 2026 · Public health nutrition
Objective The present study aimed to investigate the association between adherence to the Dietary Approaches to Stop Hypertension (DASH) diet and the risk of depression and anxiety severity in a large group of Iranian adults. Design In…
View details →Bayar E, Cengiz T, Erdoğan F et al. · 2026 · BMC geriatrics
BACKGROUND: Hip fractures represent a major public health concern due to their increasing incidence in the aging population and their association with significant morbidity and mortality. Comorbidities are known to complicate both the…
View details →Ebadani L, Reese JA, Sitlani CM et al. · 2026 · Journal of women's health (2002)
Introduction In the United States, cardiovascular disease (CVD) is a leading cause of death among American Indian women. We examined the associations of parity and pregnancy complications (history of preeclampsia, protein in urine,…
View details →Kyriakidis I, Katsarou SD, Zervou MI et al. · 2026 · Genes
Background/objectives Inherited variants in IKZF1 and CDKN2A/2B are among the most consistently reported germline susceptibility markers for childhood acute lymphoblastic leukemia (ALL). Nonetheless, effect sizes differ across ancestry…
View details →Wu Y, Xu R, Long Q et al. · 2026 · Pediatric research
Background Although asthma and obesity are independently associated with neurodevelopmental disorders, whether their co-occurrence is associated with a higher burden of these disorders remains unclear. Methods Using NHIS data from children…
View details →Arık H, Tınazlı M, Süer K · 2026 · Medicina (Kaunas, Lithuania)
Backgroun d and Objectives : Urinary tract infections (UTIs) represent one of the most frequently encountered bacterial infections in clinical practice. Although vitamin D (vit D) is recognised for its immunomodulatory properties, its…
View details →Ramirez De Los Santos ML, Ramírez-De Los Santos S, Becerra Solano LE et al. · 2026 · Nutricion hospitalaria
Introduction Introduction: metabolic syndrome (MS) affects approximately 27 % of the global population and represents a growing public health concern. Identifying factors associated with its presence is essential for prevention, early…
View details →Wang L, Yue Q, Li KQ et al. · 2026 · BMC cancer
Purpose This study aimed to systematically evaluate the associations between oral health conditions, including periodontitis, tooth loss, and dental caries, and colorectal cancer (CRC) risk. Materials and methods PubMed, Embase, the…
View details →Boncyk C, Connell J, Stollings JL et al. · 2026 · Critical care medicine
Objectives ICU patients are at increased risk of inappropriate prescribing and high drug burden. These patients also often experience cognitive impairment, physical disability, and increased mortality after discharge. We investigated…
View details →Ye H, Tian Y, He G et al. · 2026 · Journal of clinical medicine
Objectives : This study aimed to investigate the association between postpartum hemorrhage (PPH) and the risk of postpartum depressive and anxiety symptoms. Methods : A retrospective cohort study of twin delivery was conducted at a…
View details →Jaafari Z, Hassanzadeh J, Sayadi M et al. · 2026 · Health science reports
Background and aims The variation in the incidence of type 2 diabetes mellitus (T2DM) in different countries is associated with various factors. This study aimed to examine the factors linked to the difference in the incidence of T2DM…
View details →Sabri H, Baniameri S, Kataria P et al. · 2026 · Journal of periodontology
Background Periodontitis, a chronic inflammatory disease, is linked to systemic conditions such as cardiovascular and kidney disease. Serum α-Klotho, an anti-aging protein with anti-inflammatory properties, has been associated with…
View details →Hendricks S, Huynh A, Burns DT et al. · 2026 · AIDS research and treatment
Purpose To determine whether sociodemographic factors, including residence in rural/frontier versus urban settings, are associated with differences in HIV viral suppression rates among people living with HIV in Wyoming with one or more…
View details →Xiong Y, Huang J, Wu Y et al. · 2026 · Renal failure
Physical activity (PA) is of great importance for peritoneal dialysis (PD) patients with sarcopenia. However, the optimal PA dose for sarcopenia in PD patients remains unclear. This study adopted a cross-sectional design and enrolled PD…
View details →Luo M, Wang Y, Wang Y et al. · 2026 · The journal of maternal-fetal & neonatal medicine : the official journal of the European Association of Perinatal Medicine, the Federation of Asia and Oceania Perinatal Societies, the International Society of Perinatal Obstetricians
Objective The optimal interpregnancy interval (IPI) for preventing hypertensive disorders of pregnancy (HDP) remains unclear, and whether this association is modified by maternal baseline characteristics has not been well established. This…
View details →Revilla-León M, Gómez-Polo M, Barmak AB et al. · 2026 · The Journal of prosthetic dentistry
Statement of problem As experience with intraoral scanners (IOSs) and scientific evidence has grown, factors compromising IOS accuracy have been identified. Limited interdental space between tooth preparations lead to the bridge scanning…
View details →Steinharter JA, Chou J, Ilagan CH et al. · 2026 · Journal of the American College of Surgeons
Background An adequate future liver remnant volume (FLRV%) reduces the risk of posthepatectomy liver failure (PHLF). This study evaluates (1) the association of FLRV% with grade 4/5 morbidity and (2) the safe FLRV% threshold for PHLF- and…
View details →Seale L, Bates N, Tumin D et al. · 2026 · European journal of obstetrics, gynecology, and reproductive biology
Objective To examine the association between age at menarche and polycystic ovary syndrome (PCOS) diagnosis among US women aged 20-49 years. Study design Our retrospective cross-sectional analysis used data from the 2022-2023 National…
View details →Wang X, Zhang R, Chai W et al. · 2026 · Medicine
The incidence of IgA nephropathy (IgAN) is increasing, and some observational studies reported the potential correlation of polycystic ovary syndrome (PCOS) with the risk of IgAN. We performed a bidirectional Mendelian randomization…
View details →Gonzalez W, Isla J, Barba D et al. · 2026 · Journal of ISAKOS : joint disorders & orthopaedic sports medicine
Background Anterior tibial translation (ATT) measured on magnetic resonance imaging (MRI) is a reproducible marker of anterior cruciate ligament (ACL) deficiency. However, its longitudinal evolution after ACL reconstruction (ACLR) and its…
View details →Bax EA, Colyn W, Bellemans J et al. · 2026 · Osteoarthritis and cartilage open
Objectives This study investigated the association between alpha angles of the hip and tibial genu varum in a healthy population with equal male-to-female distribution. It also examined sex-based differences, explored the impact of sports…
View details →Motoji Y, Kitamura T, Naito N et al. · 2026 · Interdisciplinary cardiovascular and thoracic surgery
Objectives This study aimed to investigate changes in haematoma thickness (HT) and the maximum ascending aortic diameter (MAD) early after onset and their association with in-hospital disease progression in type A intramural haematoma…
View details →Mannen R, Maeda K, Inoue T et al. · 2026 · Journal of frailty, sarcopenia and falls
Objectives Osteosarcopenia is characterized by the coexistence of sarcopenia and osteoporosis. This comorbid condition is thought to negatively affect functional outcomes. In this study, we investigated the negative impact of…
View details →Othus M, Truong TG, Sharon E et al. · 2026 · JCO oncology practice
Purpose Multiple reports have suggested that receiving immunotherapy infusions earlier in the day is associated with improved outcomes, including longer overall survival (OS) and lower toxicity rates. However, the definition of early…
View details →Tabeta A, Tsutsumi Y, Hoshi H et al. · 2026 · BMC surgery
Background Perforated peptic ulcer is a critical emergency disease requiring surgery, and postoperative intra-abdominal abscess (IAA), an organ/space surgical site infection (SSI), is a common complication. Intraoperative irrigation is a…
View details →Hsu JZ, Gu K, Nguyen B et al. · 2026 · The Annals of otology, rhinology, and laryngology
Objective Estrogen has been found to impact cochlear blood flow and auditory function, but epidemiological studies on menopause and hearing are inconsistent. This study investigates the associations of menopause, its age at onset,…
View details →Keel E, Kalimeris S, Adams M et al. · 2026 · The journal of maternal-fetal & neonatal medicine : the official journal of the European Association of Perinatal Medicine, the Federation of Asia and Oceania Perinatal Societies, the International Society of Perinatal Obstetricians
Background Infants born before 32 weeks of gestation are at high risk of developing intraventricular hemorrhage (IVH), which is associated with significant mortality and morbidity as well as long-term neurodevelopmental impairment. There…
View details →Maharjan U, Kauppila JH · 2026 · Surgical oncology
Background Previous studies on hospital volume of gastrectomy and mortality in gastric cancer are conflicting, with some suggesting improved short-term outcomes in higher volume hospitals and fewer studies demonstrating consistent findings…
View details →Molla HT, Gashu D, Stoecker B et al. · 2026 · Genes
Background Etiologies of neural tube defects (NTDs) are multifactorial. Genetic, epigenetic and environmental factors may contribute to their reported variation in prevalence across the globe. Ethiopia has among the highest reported NTD…
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