e-ISSN: Pending
WASTE Journal

Browse the failure-mode index

12,263 real negative results, null findings, and replication failures in Medicine. Search the index →

WASTE indexes published research — it does not host or republish full papers. Each entry is a metadata record compiled from open scholarly databases; the abstract is shown in full only where the paper is openly licensed, otherwise a short excerpt under fair use. Classifications are automated and approximate.

Negative / Null Result ReportMedicine

Effect of Anti-Tubercular Therapy Duration (6 Months versus ≥9-Months) on Treatment Outcomes in Serpiginous-Like Choroiditis: A Multicenter Retrospective Observational Study.

Sharma I, Basu S, Nasir S et al. · 2026 · Ocular immunology and inflammation

Purpose Serpiginous-Like Choroiditis (SLC) is considered to be a subtype of tuberculosis associated uveitis and has been treated with either 6 or 9 months of Anti Tuberculosis therapy (ATT). However, ATT is associated with several adverse…

View details →
Negative / Null Result ReportMedicine

Utility of ophthalmologic evaluation for papilledema in pediatric emergency department encounters for shunt failure: a single-center retrospective study.

Tora MS, Fofana F, Roach K et al. · 2026 · Journal of neurosurgery. Pediatrics

Objective In shunted pediatric hydrocephalus patients, the potential for shunt failure is a frequent cause of emergency department (ED) presentation. The assessment of papilledema through ophthalmological fundoscopic examination (OFE) is…

View details →
Negative / Null Result ReportOpen accessMedicine

Posterolateral plating increases peroneal tendon thickness without affecting clinical outcomes: a ultrasonographic comparative study of 76 SER ankle fractures.

Labronici PJ, de Campos JP, de Araújo Almeida JP et al. · 2026 · European journal of orthopaedic surgery & traumatology : orthopedie traumatologie

OBJECTIVES: To evaluate, using ultrasonography and the AOFAS (The American Orthopaedic Foot and Ankle Society) score, changes in the peroneal tendons of patients with ankle fractures resulting from a supination-external rotation (SER)…

View details →
Negative / Null Result ReportOpen accessMedicine

Sexual functioning after total versus subtotal laparoscopic hysterectomy-long term follow up results after 7 years.

Brodkorb T, Elnahrawy A, Spaich S et al. · 2026 · Archives of gynecology and obstetrics

Purpose The aim of this study was to evaluate sexual function in the long term after total laparoscopic hysterectomy (TLH) versus laparoscopic supracervical hysterectomy (LASH) in patients with benign indications. Methods As part of a…

View details →
Negative / Null Result ReportOpen accessMedicine

Clinical Assessment of the Effect of Hypericum perforatum Chewing Gum on Salivary Streptococcus mutans Count, pH, Plaque Index, and Gingival Bleeding: A Randomized Clinical Trial.

Jamali A, Hamishehkar H, Memar MY et al. · 2026 · Clinical and experimental dental research

Objectives Hypericum perforatum L. offers several beneficial effects, for example antioxidant, antitumor, wound healing. Our aim was to ascertain the effect of H. perforatum extract gum on salivary Streptococcus mutans count, pH, plaque…

View details →
Negative / Null Result ReportMedicine

Evaluation of predictive factors for conception after saline infusion sonosalpingography.

Ramadhan D, Al-Rasheedy M, Alsarraj L · 2026 · Medicinski glasnik : official publication of the Medical Association of Zenica-Doboj Canton, Bosnia and Herzegovina

Objective For evaluation of predictive factors of sponataneous conception after saline infused sonosalpingography (SIS). Method A prospective study was conducted from August 2023 to December 2024 at reproductive medial unit  at…

View details →
Negative / Null Result ReportMedicine

Clinical real-world data evaluation: comparison of central macular thickness after anti-VEGF treatment in diabetic macular edema patients treated with or without topical anti-glaucoma agents.

Baybora H, Özal E, Özal SA · 2026 · BMC ophthalmology

Background There are research findings suggesting that antiglaucoma agents may reduce aqueous humor outflow and decrease the elimination of intravitreally administered anti-vascular endothelial growth factor agents, prolonging their…

View details →
Negative / Null Result ReportOpen accessMedicine

Mid-Term Oncological Outcomes of Vaginal Natural Orifice Transluminal Endoscopic Surgery Compared with Total Laparoscopic Hysterectomy for Early-Stage Endometrial Cancer: A Single-Center Retrospective Study.

Imai K, Abe J, Chikazawa K et al. · 2026 · Journal of clinical medicine

Background/Objectives : Vaginal natural orifice transluminal endoscopic surgery (vNOTES) is increasingly being used to avoid abdominal incisions; however, its mid-term oncological safety in endometrial cancer remains unclear. Methods :…

View details →
Negative / Null Result ReportOpen accessMedicine

Efficacy and safety of Ashwagandha root extract sustained-release (AshwaSR) capsules in healthy adult, stressed subjects: A randomized, double-blind, placebo-controlled, parallel-group, 3-arm clinical trial.

Thanawala S, Shah R, Alluri KV et al. · 2026 · Medicine

Background The adaptogenic effects of Ashwagandha root extract are evident. An earlier study showed the therapeutic effects of a once-daily sustained-release (SR) formulation (300 mg) of Ashwagandha root extract over an extended period.…

View details →
Negative / Null Result ReportOpen accessMedicine

Assessing the effect of deficit irrigation and biochar application on soil water depletion, root distribution, and water productivity of cucumber in semi-arid West Texas.

Kafle A, Singh S, Singh M et al. · 2026 · Frontiers in plant science

Understanding crop root growth and distribution and soil water depletion under water deficit conditions is critical for developing sustainable production practices for cucumber ( Cucumis sativus L.) in semi-arid regions like West Texas.…

View details →
Negative / Null Result ReportMedicine

CT-Based Blood Burden Scores for Predicting Shunt-Dependent Hydrocephalus After Aneurysmal Subarachnoid Hemorrhage: A Comparative Analysis of Quantitative and Qualitative Scoring Systems.

Sarkis H, Kerhani AA, Hedderich DM et al. · 2026 · World neurosurgery

Background/objective Shunt-dependent hydrocephalus represents a major complication of aneurysmal subarachnoid hemorrhage (aSAH), yet no universally adopted CT-based prediction tool exists. Fisher-based scales suffer from a ceiling effect…

View details →
Negative / Null Result ReportMedicine

Surface roughness and surface microhardness of bulk-fill and conventional resin composites after erosive-abrasive cycles: A laboratory study.

Devletli Ozygit L, Eyuboglu GB · 2026 · American journal of dentistry

Purpose To investigate comparatively the changes in surface roughness and surface microhardness of resin composites applied with traditional incremental layering technique and bulk-fill resin composites after erosive/abrasive applications.…

View details →
Negative / Null Result ReportOpen accessMedicine

Effects of load carriage methods on fall risk and gait variability during stair ascent: a functional data analysis approach.

Zhang X, Li Y, Fang Y et al. · 2026 · Frontiers in bioengineering and biotechnology

Objective Based on the existing research that predominantly focuses on loaded level walking or employs discrete-point methods to analyze stair negotiation, this study utilizes functional data analysis to systematically investigate the…

View details →