12,263 real negative results, null findings, and replication failures in Medicine. Search the index →
WASTE indexes published research — it does not host or republish full papers. Each entry is a metadata record compiled from open scholarly databases; the abstract is shown in full only where the paper is openly licensed, otherwise a short excerpt under fair use. Classifications are automated and approximate.
Masilamani PK, Muhammad NB, Sankaran RS et al. · 2026 · Clinics (Sao Paulo, Brazil)
Introduction During the Coronavirus Disease (COVID-19) pandemic, public and healthcare workers were recommended to use Personal Protective Equipment (PPE) to prevent the spread of infection. With the increased use of different types of…
View details →Meng F, Qi H, Ding Z et al. · 2026 · Molecular horticulture
Fruit cracking severely affects tomato quality and yield. By utilizing genetic transformation, knockout of the SlPMEI27 gene can enhance the activity of pectin methylesterases (PMEs). Here, by conducting an immunofluorescence analysis, we…
View details →Zavala P, Eggleston GG, Greufe NA et al. · 2026 · Orthopaedic journal of sports medicine
Background Primary anterior cruciate ligament reconstructions (ACLRs) with extensor mechanism autografts (bone-patellar tendon-bone [BTB] or quadriceps tendon [QT]) have been reported to have lower quadriceps strength symmetry outcomes 6…
View details →Refai OM, Abdelfattah Mohamed AM, Ali El-Fiky AM · 2026 · BMC oral health
Background Mandibular complete dentures often lack stability, leading to prolonged occlusion and disocclusion times. Immediate-loading implant overdentures can improve functional control, but evidence comparing splinted and non-splinted…
View details →Dos Santos Lopes H, Waiteman MC, Serrão FV et al. · 2026 · Scandinavian journal of medicine & science in sports
It remains unclear whether people with traumatic-onset patellofemoral pain (PFP_T) present with the same physical and non-physical changes as people with gradual-onset patellofemoral pain (PFP_A). In this cross-sectional study, we aimed to…
View details →Wani SQ, Matia M, Jayaprakasan AK et al. · 2026 · BMC palliative care
Background Living with life-limiting illnesses (LLIs) is psychologically distressing, even more so in areas with a complicated terrain and which are conflict-prone, where insecurity, displacement, and limited healthcare access adds to the…
View details →Manzoor M, Banday MS, Para BA et al. · 2026 · Virus research
Background/objectives The COVID-19 pandemic precipitated a global rise in psychological morbidities, markedly increasing depression, anxiety, and stress. This study provides early region-specific evidence from Kashmir on the post-pandemic…
View details →Xu Y, Tan G, Zhu R · 2026 · Scientific reports
Ferroptosis, the most common programmed cell death process, and immune checkpoints play increasingly prominent roles in glioma. However, the effects of ferroptosis on immune checkpoints on glioma remain unclear. The intracellular ROS…
View details →Şahin Çelik B, Ağdaş G, Genç V · 2026 · BMC cancer
Objective To compare the real-world outcomes of perioperative chemotherapy (ChT) and neoadjuvant chemoradiotherapy (CRT) in patients with locally advanced resectable distal esophageal and esophagogastric junction (EGJ) adenocarcinomas,…
View details →Jiang J, Yang X, Du F et al. · 2026 · Medicine
Morphological changes in the meibomian glands following treatment of pediatric chalazion were assessed using an ocular surface analyzer, and the effects of surgical versus conservative management on gland morphology were systematically…
View details →Zhang J · 2026 · PloS one
English writing competence is a significant manifestation of students' second language proficiency. However, comprehensive synchronic empirical research remains scarce regarding how students at application-oriented universities perform in…
View details →Dongmo F, Kom B, Akiki À Tsang G et al. · 2026 · Annals of medicine and surgery (2012)
Background Sclerocarya birrea is used in traditional medicine for the treatment of many diseases, including gastritis, diarrhea, dysentery, and hemorrhoids. The objective of this study was to evaluate the efficacy of Sclerocarya birrea…
View details →Çi̇men HN, Uğur S, Çıralı A et al. · 2026 · Nurse education in practice
Aim The aim of this study was to evaluate the effect of podcast-based educational content delivered to students on their knowledge, awareness and anxiety levels regarding Human Papillomavirus (HPV). Method This randomized controlled…
View details →Wang S, Ma J, Ma S et al. · 2026 · Zhongguo gu shang = China journal of orthopaedics and traumatology
Objective To compare clinical efficacy of TightRope button-loop titanium plate elastic fixation and hollow tension screw fixation in treating ankle fractures with accompanying tibiofibular syndesmosis injury. Methods A retrospective…
View details →Rezaiyan A, Sohrabi Z, Ramezani N et al. · 2026 · Journal of education and health promotion
Background Pregnancy is associated with a wide range of physiologic and psychologic changes that could affect a mother's body image and maternal-fetal attachment. One of the presented interventions regarding body image and maternal fetal…
View details →Ha D, Jung K, Choi H et al. · 2026 · Veterinary medicine and science
Background Botanical ingredients can function as adjunctive therapies for managing inflammatory skin diseases. Objectives This study aimed to investigate the anti-inflammatory effects of a mixture of Boswellia serrata, Commiphora myrrha,…
View details →Salim O, Chari A, Tahir MZ · 2026 · Child's nervous system : ChNS : official journal of the International Society for Pediatric Neurosurgery
Purpose Hemispherotomy is an established treatment for children with drug-resistant epilepsy. Recent reports have suggested a superiority of outcomes with the vertical approach compared to the traditional lateral approach. This study…
View details →Jaiswal M, Hazare A, Karia H et al. · 2026 · Cureus
Introduction Growth assessment is a fundamental process in orthodontics as accurate determination of skeletal maturity guides the timing of treatment intervention. Biochemical and radiographic indicators can be used to evaluate growth…
View details →Tan A, Liu J, Chen X et al. · 2026 · Hematology (Amsterdam, Netherlands)
Objectives To evaluate the efficacy and safety of sirolimus-based treatment regimens in patients with antinuclear antibody (ANA)-positive immune thrombocytopenia (ITP). Methods This retrospective single-center study enrolled patients with…
View details →Glavina A, Gravić A, Demo J et al. · 2026 · Healthcare (Basel, Switzerland)
Background/objectives Over the past decade, the popularity of smokeless tobacco products, particularly heated tobacco products (HTPs), has increased among adolescents and young adults. This study aimed to determine the effects of HTPs and…
View details →Dogan R, Kulaksiz Y, Yeni̇gun A et al. · 2026 · Sleep & breathing = Schlaf & Atmung
Objective Diagonal ear lobule fold (DELF)(Frank sign); It is a diagonal fold in the earlobe at an angle of about 45°, running diagonally from the tragus to the edge of the auricle at varying depths. In our study, the relationship between…
View details →Ruengsiriphakakul S, Bumrerraj S, Thaenkham T · 2026 · Journal of education and health promotion
Background Iodine deficiency remains a global public health problem. Urinary iodine concentration (UIC) in pregnant women is a key indicator of iodine status in the population. Knowledge (K), attitude (A), and practice (P) levels of…
View details →Zhang T, Xie Y, Yang C et al. · 2026 · Virulence
The Taiwan-I-type infectious bronchitis virus (IBV) has become one of the most dominant and threatening genotypes circulating in China poultry farms. In this study, we characterized the Taiwan-I-type IBV strain GX-NN200723 and evaluated…
View details →Rathore S, Bhushan J, Uppal AS et al. · 2026 · Journal of conservative dentistry and endodontics
Background Treatment of teeth with immature apices is difficult to manage by conventional endodontics. Apical barrier formation using bioceramic materials offers a biologically favorable solution, providing a hermetic seal that supports…
View details →Loomba P, Nayak M, Podder S et al. · 2026 · Annals of African medicine
Background Postoperative nausea and vomiting (PONV) are a prevalent complication after laparoscopic surgeries, with an incidence reaching up to 63% without antiemetic prophylaxis. Objectives To evaluate the efficacy of dexamethasone and…
View details →Biyik Bayram S, Gülnar E, Çalişkan N et al. · 2026 · Computers, informatics, nursing : CIN
This study investigated the effect of virtual simulation of parenteral medication administrations on nursing students' knowledge and skills. This randomized controlled experimental study adopted a pretest-posttest research design. The…
View details →Gökay GD, Şenol M, Oyar P et al. · 2026 · BMC oral health
Purpose The purpose of this study was to assess the surface roughness, color stability, and contact angle of lithium disilicate glass-ceramic (LD) and zirconia-reinforced lithium silicate (ZLS) ceramics following surface finishing and to…
View details →Bastug Guven E, Genc Sen O · 2026 · Medical science monitor : international medical journal of experimental and clinical research
BACKGROUND Sodium hypochlorite (NaOCl) is the most commonly used irrigant in root canal treatment because of its antimicrobial activity and tissue-dissolving capacity. Since these properties are related to its physicochemical…
View details →Tamura Y, Tojima H, Takizawa D et al. · 2026 · Cancers
Background The number of elderly patients with hepatocellular carcinoma (HCC) has been increasing worldwide. This study aimed to evaluate the clinical outcomes of stereotactic body radiation therapy (SBRT) for patients aged ≥80 years with…
View details →Xie S, Hong W, Huang L et al. · 2026 · Brazilian journal of otorhinolaryngology
Objective This study aimed to evaluate the effect of Hyperbaric Oxygen Therapy (HBOT) combined with steroids as initial treatment on the prognosis of patients with Idiopathic Sudden Sensorineural Hearing Loss (ISSNHL) by using propensity…
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