A streamlined approach for gene editing in non-obese diabetes (NOD) mice via CRISPR/Cas9.
Cho; Lionakis; Khillan · 2026 · Laboratory animal research
WASTE classifies this as Failed Experiment Report · AI classification, approximate
An experimental approach did not work as intended — learn what to avoid before investing the same effort.
Abstract (excerpt)
Gene targeting via CRISPR/Cas9 has become a powerful tool to create animal models for human genetic disorders. Although CRISPR/Cas9 mediated gene editing is relatively simple, factors such as mouse strain, breeding performance, and quality…
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Metadata source: PubMed · DOI 10.1186/s42826-026-00281-x