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Browse the failure-mode index

12,262 real negative results, null findings, and replication failures in Medicine. Search the index →

WASTE indexes published research — it does not host or republish full papers. Each entry is a metadata record compiled from open scholarly databases; the abstract is shown in full only where the paper is openly licensed, otherwise a short excerpt under fair use. Classifications are automated and approximate.

Negative / Null Result ReportMedicine

Seroprevalence and risk factors of toxoplasma gondii infection in goats from underreported Midland and lowland regions of Algeria.

Benattia, Saidi, Gouzi et al. · 2026 · Veterinary parasitology, regional studies and reports

Toxoplasmosis is a parasitic disease affecting both humans and animals and is caused by the protozoan parasite Toxoplasma gondii. In livestock, the infection leads to significant economic losses, mainly due to reproductive disorders such…

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Negative / Null Result ReportMedicine

Plaque phenotypes across remodeling patterns in vertebrobasilar atherosclerosis: a high-resolution magnetic resonance vessel wall imaging study.

Liu, Xu, Zhong et al. · 2026 · Quantitative imaging in medicine and surgery

Intracranial atherosclerosis is the predominant etiology of ischemic stroke in East Asian populations. Atherosclerotic progression frequently involves concomitant vascular remodeling, and stroke risk profiles may vary across distinct…

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Negative / Null Result ReportMedicine

Predictors of postoperative morbidity and delayed initiation of adjuvant chemotherapy after cytoreductive surgery in advanced-stage epithelial ovarian cancer.

Çaltek, Yassa, Şahin et al. · 2026 · World journal of surgical oncology

This study aimed to identify the factors predicting postoperative morbidity after cytoreductive surgery in patients with advanced-stage epithelial ovarian cancer, to evaluate the effect of this morbidity on the time to initiation of…

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Negative / Null Result ReportMedicine

A randomized controlled trial comparing limbal-conjunctival autograft with conjunctival autograft in recurrent pterygium surgery with intraoperative application of 0.02% mitomycin C.

Peng, Wang, Gong et al. · 2026 · International ophthalmology

To compare the outcomes of conjunctival graft (CAG) versus limbal-conjunctival autograft (LCAG) in preventing recurrence after surgery for recurrent pterygium with intraoperative application of 0.02% mitomycin C(MMC). This prospective…

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Negative / Null Result ReportMedicine

Population Genetic Structure and Biogeographic Distribution of Tropical Halodule uninervis in the Bohol Sea and Adjacent Waters in the Philippines.

Singson, Takayama, Suyama et al. · 2026 · Ecology and evolution

Halodule uninervis plays a critical role in the seagrass ecosystem because its opportunistic traits facilitate expansion and persistence under changing environmental conditions. Yet the population genetic structure and connectivity of this…

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Negative / Null Result ReportMedicine

Sex-specific distribution of the uric acid-to-HDL cholesterol ratio and its association with arterial stiffness in a Japanese health check-up population: a cross-sectional analysis.

Qu, Jiang · 2026 · Frontiers in endocrinology

The uric acid to HDL-cholesterol ratio (UHR) is a composite marker of metabolic and inflammatory imbalance. Although a previous study in a Japanese health check-up population reported a positive and nonlinear association between UHR and…

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Negative / Null Result ReportMedicine

Cross-Sectional and Longitudinal Associations between Dietary Variety Score and Hippocampal and Grey Matter Volume Changes among Community-Dwelling Older Japanese Adults: Findings from the NEIGE Cohort.

Ohaku, Murayama, Machida et al. · 2026 · Journal of epidemiology

Dietary diversity is associated with enhanced cognitive function and reduced dementia risk among older adults; however, its relationship with structural brain ageing remains unclear. We examined cross-sectional and longitudinal…

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Negative / Null Result ReportMedicine

Association of Race and Ethnicity With Computed Tomography Head Utilization in Children Presenting to the Emergency Department With an Unprovoked Seizure.

Kannikeswaran, Sivaswamy, Przyklenk et al. · 2026 · Pediatric neurology

Although not routinely recommended, computed tomography (CT) head are frequently performed in children presenting to emergency department (ED) with seizures. Racial and ethnic disparities have been reported in pediatric ED imaging. Our…

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Negative / Null Result ReportMedicine

Chemical, Biological, Radiological, and Nuclear (CBRN) Disaster Preparedness among Anesthesiologists: A Multidomain Cross-Sectional Study.

Gondode, Duggal, Malviya et al. · 2026 · Disaster medicine and public health preparedness

To assess the current levels of knowledge, attitudes, practices (KAP), and institutional support regarding Chemical, Biological, Radiological, and Nuclear (CBRN) disaster preparedness among anesthesia professionals in India, and to…

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Negative / Null Result ReportMedicine

Diagnostic performance of computed tomography colonography following incomplete colonoscopy and its associated factors: A single-centre retrospective study.

Mohd Hayati, Abdul Wahid, Shamsidi et al. · 2026 · The Medical journal of Malaysia

Incomplete colonoscopy presents an important clinical challenge, as segments of the colon that are not visualised may contain significant pathology. Computed tomography colonography (CTC) provides a minimally invasive alternative for…

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Negative / Null Result ReportMedicine

A real-world data analysis of the impact of clonal hematopoiesis of indeterminate potential on therapeutic efficacy and adverse events of immune checkpoint inhibitors.

Fujita, Ishibashi, Aoyama et al. · 2026 · Cancer

Clonal hematopoiesis of indeterminate potential (CHIP) has been implicated in systemic inflammation. Although immune checkpoint inhibitors (ICIs) have transformed cancer care, their response rates remain modest, and some patients…

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Negative / Null Result ReportMedicine

Impact of ABCB1 (rs1045642) polymorphism on antipsychotic-induced extrapyramidal symptoms in Egyptian patients with schizophrenia.

Ahmed, Moawad, Tarek et al. · 2026 · Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association

The ABCB1 polymorphisms may influence risperidone-induced extrapyramidal symptoms (EPS) in schizophrenia. This cross-sectional study examined the relationships among ABCB1 variants, clinical factors, and objective, subjective EPS in 150…

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