Negative / Null Result ReportMedicine
Savaş, Kavrut, Engin · 2026 · Foods (Basel, Switzerland)
In the study, the effects of adding sour cheery seed powder at different concentrations (0%, 0.5%, 1%, and 1.5%) on the pH, water content, lipid oxidation, cooking loss, color, TPC, antioxidant activity (DPPH and ABTS), texture, and…
View details →Negative / Null Result ReportMedicine
Tian, Zhao, Huang et al. · 2026 · Foods (Basel, Switzerland)
This study focuses on the storage process of coffee beans, employing electron beam irradiation (EBI) to investigate the comprehensive effects of different irradiation doses on coffee beans and their storage process, including…
View details →Negative / Null Result ReportMedicine
Celik · 2026 · Applied clinical informatics
This study applies object-centric process mining (OCPM) techniques to analyze laparoscopic cholecystectomy (LC) procedures. Traditional process mining techniques are limited in analyzing workflows involving multiple interacting entities…
View details →Negative / Null Result ReportMedicine
Storck, Schönefeld, Bellstedt et al. · 2026 · Journal of surgical education
Prior knowledge activation (PKA) has long been considered a cornerstone of surgical education, yet recent meta-analyses reveal conflicting evidence regarding its effectiveness. This study examined when PKA enhances surgical education by…
View details →Negative / Null Result ReportMedicine
Manikanta, Kumar, Mani et al. · 2026 · Scientific reports
Distributed generators (DGs) are recent emerging technologies which are executed in distribution system (DS) to reduce power losses (PLs). However, optimal location and sizing of DG (OLSDG) remain a challenging combinatorial optimization…
View details →Negative / Null Result ReportMedicine
Wu, Zhang, Xi et al. · 2026 · Critical reviews in oncology/hematology
Ovarian cancer remains an immunologically "cold" tumor, with early all-comer immune checkpoint inhibitor (ICI) trials largely negative despite underlying immunogenicity. This review takes a clinician-centric, stage-specific view linking…
View details →Negative / Null Result ReportMedicine
Partlova, Comley, Haigh et al. · 2026 · Experimental neurology
Spinal muscular atrophy (SMA) is characterized by motor neuron loss and neuromuscular junction (NMJ) pathology. Although SMN-upregulating therapies such as Nusinersen markedly improve survival and motor function for many patients,…
View details →Negative / Null Result ReportMedicine
Li, Nelson, Li et al. · 2026 · Cancer research
Synovial sarcoma (SyS) incorporates the SS18::SSX fusion oncoprotein into GLTSCR1-containing BRG1/BRM and associated factors (GBAF) complexes, which confers a dependency on the GBAF subunit BRD9. However, SyS clinical trials with multiple…
View details →Negative / Null Result ReportMedicine
Khairil, Benny, Jerry et al. · 2026 · Pharmaceuticals (Basel, Switzerland)
The integration of artificial intelligence (AI) into the life sciences has accelerated significantly between 2022 and 2026, accompanied by global investment exceeding USD 100 billion and widespread expectations of a transformative impact…
View details →Negative / Null Result ReportMedicine
Lee · 2026 · Journal of clinical medicine
Hypoxic-ischemic brain injury remains the leading cause of death and neurological disability after cardiac arrest. Although targeted temperature management (TTM) and other neuroprotective strategies have demonstrated promising results in…
View details →Negative / Null Result ReportMedicine
Wu, Li, Zhu et al. · 2026 · Microorganisms
The gut microbiome, often termed the human "second genome", profoundly influences host physiology through metabolic interactions, immune modulation, and gut-brain axis signaling. Dysbiosis is implicated in the pathogenesis of obesity,…
View details →Negative / Null Result ReportMedicine
Mulita, Kouroupi, Verras et al. · 2026 · Diagnostics (Basel, Switzerland)
Background and Clinical Significance: Ganglioneuromas are rare benign tumors of neural crest origin, with gastrointestinal involvement being uncommon and ampullary localization exceptionally rare. Pancreatic neuroendocrine tumors (NETs)…
View details →Negative / Null Result ReportMedicine
Mangano, Lerner, Mangano · 2026 · Journal of dentistry
To evaluate the 2-year clinical, radiographic, and prosthetic outcomes of 3D printed porous titanium implants supporting single crowns. This retrospective study included 70 patients (31 males, 39 females; mean age 58.4 ± 12.1 years)…
View details →Failed Experiment ReportMedicine
Xu, Hu, Cai · 2026 · PloS one
The layout of the image and the positional distribution of the objects directly affect the audience's visual focus and the effect of the message conveyed. By setting up a specific layout structure, the viewer's attention can be more…
View details →Negative / Null Result ReportMedicine
Van Rompay, Tabury, Rehnberg et al. · 2026 · Cells
Three-dimensional (3D) cardiac models, including spheroids, organoids, and organ-on-chips, are advanced systems for studying human physiology, disease, and drug responses with greater biological relevance than 2D models. As their use…
View details →Negative / Null Result ReportMedicine
Ashok, Stanicki, Thompson et al. · 2026 · The Physician and sportsmedicine
Meniscus injuries are one of the most common orthopedic pathologies. Arthroscopic partial meniscectomy can be performed if the injury has failed nonoperative management or is irreparable. Socioeconomic disparities within health insurance…
View details →Negative / Null Result ReportMedicine
Shalamov, Cromwell, Guha · 2026 · AJP reports
Background: Congenital central hypoventilation syndrome (CCHS) is a rare genetic disorder that causes alveolar hypoventilation because of impaired chemoreceptor response to hypercapnia and hypoxia occurring due to a dysfunctional central…
View details →Negative / Null Result ReportMedicine
Fujimura, Hagio, Kouzaki · 2026 · Frontiers in sports and active living
Whole-body movements in everyday tasks challenge the neuromuscular system. Prior studies have shown that appropriate postural control supports both task success and postural balance during quiet standing or under modest postural demands.…
View details →Negative / Null Result ReportMedicine
Yding Andersen, Poulsen, Wissing et al. · 2026 · Frontiers in endocrinology
The luteinizing hormone receptor (LHR) plays a pivotal role in regulating human follicular development and steroidogenesis through temporal and cell-specific expression on theca (TCs) and granulosa cells (GCs). Although LH-like activity…
View details →Negative / Null Result ReportMedicine
Singh, Patel, Tripathi et al. · 2026 · Frontiers in genome editing
Myostatin ( MSTN ) gene knockout has attracted considerable interest for enhancing meat production in livestock species due to its well-established role as a negative regulator of skeletal muscle growth. In this study, we report the…
View details →Negative / Null Result ReportMedicine
Ganjee, Bandos, Hossain et al. · 2026 · Journal of imaging informatics in medicine
Breast density is a breast cancer risk factor. The accurate quantification of breast density requires reliable segmentation of dense tissue in mammograms, but it is a challenging task due to large variations in tissue appearance across…
View details →Negative / Null Result ReportMedicine
Li, Lai, Zou et al. · 2026 · Cellular & molecular immunology
Systemic lupus erythematosus (SLE) pathogenesis involves the dysregulated production of mutated, high-affinity autoantibodies, a process primarily orchestrated within germinal centers (GCs). However, the precise regulatory mechanisms…
View details →Negative / Null Result ReportMedicine
Lu, Liu, Guo et al. · 2026 · Scientific reports
The prognosis of heart failure is highly dependent on patient self-management, and short-video platforms have become a key channel for the public to access information about heart failure (HF). This cross-sectional study systematically…
View details →Negative / Null Result ReportMedicine
Gosavi, Sritharan, Bell et al. · 2026 · Annals of hepato-biliary-pancreatic surgery
Perioperative chemotherapy is frequently used for resectable colorectal liver metastases (CRLM), despite persistent uncertainty regarding the extent of its survival benefit. This perspective revisits the evidence supporting this practice…
View details →Failed Experiment ReportMedicine
Lizwan, Cynthia Chia · 2026 · Journal of cardiothoracic surgery
Early chest drain removal and discharge are standard in enhanced-recovery protocols after video-assisted thoracoscopic surgery (VATS) lobectomy, but rare wound complications may arise. We report a 71-year-old man who underwent uneventful…
View details →Negative / Null Result ReportMedicine
Matsumiya, Ding, Ikegami et al. · 2026 · Journal of immunology (Baltimore, Md. : 1950)
Pathogen-derived RNAs function as pathogen-associated molecular patterns (PAMPs) that activate innate immune responses through pattern recognition receptors (PRRs). While viral RNA is well established as a trigger of antiviral immunity,…
View details →Negative / Null Result ReportMedicine
Zhang, Zhang, Kwan et al. · 2026 · Social science & medicine (1982)
Urban noise pollution has become a critical environmental issue affecting residents' quality of life. Existing research struggles to capture heterogeneity in noise sensitivity across different populations and cannot precisely quantify the…
View details →Negative / Null Result ReportMedicine
Yang, Yang, Du et al. · 2026 · BMC cancer
Accurate prognostic assessment remains challenging in patients with hepatocellular carcinoma (HCC). Although the fibrosis-4 (FIB-4) index is widely used for non-invasive evaluation of liver fibrosis, its prognostic value in HCC remains…
View details →Negative / Null Result ReportMedicine
Sun, Wang, Lai et al. · 2026 · Neural regeneration research
The regulatory network of the spleen, a densely innervated immune hub, undergoes pathological remodeling following spinal cord injury. Whether targeted electrical stimulation of the spleen at specific frequencies can reverse peripheral…
View details →Negative / Null Result ReportMedicine
Chen, Hu, Peng et al. · 2026 · Journal of immunology research
This multicenter study aimed to analytically compare the performance of automated quantitative assays-chemiluminescence immunoassay (CLIA) and multiplexed bead immunoassay (MBI)-for detecting anti-Ro/La antibodies in Chinese patients with…
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