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WASTE Journal

Browse the failure-mode index

12,262 real negative results, null findings, and replication failures in Medicine. Search the index →

WASTE indexes published research — it does not host or republish full papers. Each entry is a metadata record compiled from open scholarly databases; the abstract is shown in full only where the paper is openly licensed, otherwise a short excerpt under fair use. Classifications are automated and approximate.

Negative / Null Result ReportMedicine

Exertional leg pain is associated with ıncreased disease activity and musculoskeletal ınvolvement, but not MEFV genotype, in familial Mediterranean fever.

Ösken, Çetin · 2026 · Irish journal of medical science

Familial Mediterranean fever (FMF) is characterized by recurrent inflammatory attacks and marked clinical heterogeneity. Exertional leg pain (ELP) is a common but underrecognized manifestation. We aimed to evaluate the association of ELP…

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Negative / Null Result ReportMedicine

Comparison of CO 2 Laser and Microdebrider in the Surgical Treatment of Pediatric Recurrent Respiratory Papillomatosis: A Retrospective Analysis.

Yerkezhan, Sagandykova, Baurzhan et al. · 2026 · Bioengineering (Basel, Switzerland)

Background . Recurrent respiratory papillomatosis (RRP) in children remains a pressing issue in pediatric otolaryngology, characterized by a chronic course, frequent relapses, and the need for repeat surgical interventions. The aim of this…

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Negative / Null Result ReportMedicine

Prognostic Value of Right Ventricular Performance and Left Atrial Mechanical Efficiency in Paroxysmal Atrial Fibrillation.

Boulmpou, Pagourelias, Zormpas et al. · 2026 · Journal of cardiovascular development and disease

Background : Predicting atrial fibrillation (AF) recurrence remains a major clinical challenge, as conventional echocardiographic parameters often fail to capture the complex electro-mechanical substrate of the arrhythmia. The prognostic…

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Negative / Null Result ReportMedicine

Relationship between the Systemic ImmuneInflammation Index and Muscle Strength in Patients with Chronic Kidney Disease: A CrossSectional Study of Data from NHANES 2011-2014.

Zhang, Jia, Hou et al. · 2026 · Endocrine, metabolic & immune disorders drug targets

This study aimed to determine the relationship between Systemic Immune-Inflammation Index (SII) and muscle strength in patients with CKD. This cross-sectional study examined adults with CKD using data from the National Health and Nutrition…

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Negative / Null Result ReportMedicine

Hypothalamo-Pituitary Dysfunction and Association with Pituitary Siderosis in Adult Subjects with Transfusion-Dependent Beta-Thalassemia: all Is not Dark.

Siddiqui, Ghosh, Ahuja et al. · 2026 · Indian journal of hematology & blood transfusion : an official journal of Indian Society of Hematology and Blood Transfusion

Transfusion-dependent beta-thalassemia (TDT) is frequently associated with endocrine dysfunction secondary to hemosiderosis involving multiple organs. This study aimed to evaluate long-term endocrine dysfunction, neuroradiological…

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Negative / Null Result ReportMedicine

Progesterone-induced endometrial thickness changes do not affect singleton neonatal outcomes in frozen embryo transfer: a retrospective analysis of 6,331 newborns.

Ye, Zhang, Du et al. · 2026 · BMC pregnancy and childbirth

To evaluate whether progesterone-induced changes in endometrial thickness (EMT) affect singleton infant outcomes during frozen-thawed embryo transfer (FET) cycles. This retrospective study analyzed 6,331 singleton live births following…

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Negative / Null Result ReportMedicine

Impact of Specialty-Trained Perioperative Nurses on Operative Time, Costs, and Complications in Otolaryngologic Surgery.

Bozdemir Çakıcı, Çakıcı, Seki et al. · 2026 · Journal of perianesthesia nursing : official journal of the American Society of PeriAnesthesia Nurses

This study aimed to examine the association between perioperative nurse specialization and operative time, costs, postoperative complications, and surgical success in otolaryngologic procedures. A retrospective observational study. The…

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Negative / Null Result ReportMedicine

Comparison of inguinal hernia repair outcomes between open and laparoscopic approaches in a pediatric population: a retrospective cohort study.

Adriansyah, Fauzi, Amadeus et al. · 2026 · Annals of surgical treatment and research

Many studies compared the outcomes of hernia repair in children between open and laparoscopic techniques. However, the results still need to be clarified. Moreover, the reports from developing countries are also limited. We compared the…

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Negative / Null Result ReportMedicine

Assessment of the Diagnostic Yield of Multiple Rapid Swallows in Symptomatic Patients with Normal High-Resolution Esophageal Manometry.

Mendonça, Teixeira, Badaró et al. · 2026 · GE Portuguese journal of gastroenterology

Multiple rapid swallows (MRS) is a provocative maneuver used to assess contractile reserve (CR) in ineffective esophageal motility, but its clinical role in symptomatic patients with normal high-resolution esophageal manometry (HREM)…

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Negative / Null Result ReportMedicine

Accuracy of Ultrasound Estimation of Fetal Weight (EFW) at Term: Insights From a Malaysian Tertiary Hospital for Primary Care Implementation.

Sia, Yew, Arumugam et al. · 2026 · Obstetrics and gynecology international

Estimated fetal weight (EFW) is a key determinant of obstetrical decision-making and an independent risk factor of high perinatal morbidity and mortality. However, routine ultrasound during pregnancy test is not universally available in…

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Negative / Null Result ReportMedicine

Clinical Implications of Stroke Progressor Phenotypes defined based on ASPECTS decay and perfusion estimated infarct growth rate: insights from a large national thrombectomy registry.

Ciacciarelli, Nicolini, Saia et al. · 2026 · Neurological sciences : official journal of the Italian Neurological Society and of the Italian Society of Clinical Neurophysiology

Infarct growth rate (IGR) is highly heterogeneous among ischemic stroke patients, reflecting a spectrum of progressor phenotypes with clinical implications. We aim to compare different imaging approaches to investigate stroke progressors…

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Negative / Null Result ReportMedicine

The impact of urinary catheterization on urinary tract infection and renal function in elderly patients undergoing hip fracture surgery: A prospective randomized controlled trial.

Serttas, Uysal, Deği̇rmenci̇ et al. · 2026 · Injury

Urinary tract infection(UTI) is a common complication following hip fracture surgery in elderly patients. Urinary catheterization is frequently used to improve patient comfort during prolonged preoperative immobilization; however, its…

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Negative / Null Result ReportMedicine

Evaluating the impact of SDHAF3 p.F53L genetic variant on clinically significant QTc prolongation in patients prescribed high-risk medications: a retrospective pharmacogenetic study.

Aalibraheem, Lopez-Medina, Chahal et al. · 2026 · Pharmacogenetics and genomics

Drug-induced QT prolongation (diQTP) can lead to rare, but potentially fatal adverse effects of many medications, yet individual susceptibility varies due to both clinical and genetic factors. SDHAF3 p.F53L (rs62624461) is a genetic…

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Negative / Null Result ReportMedicine

Vertebral Rotation in Adolescent Idiopathic Scoliosis Is Primarily Curve-Magnitude Driven Rather than Age-Dependent.

Pjanić, Grivas, Jevtić et al. · 2026 · Studies in health technology and informatics

The relationship between vertebral rotation (VR), curve magnitude, and age in adolescent idiopathic scoliosis (AIS) is not yet fully understood. Although VR represents a defining feature of scoliotic deformity, it remains unclear whether…

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Negative / Null Result ReportMedicine

Dietary habits, dietary diversity, and the influence of work-related stress among male academic professionals in Ibadan, Nigeria: a cross-sectional study.

Thompson, Adeoye, Williams et al. · 2026 · Journal of health, population, and nutrition

Rapid urbanisation and occupational demands have contributed to unhealthy dietary habits in Nigeria, particularly among professionals. Male academic professionals may be especially vulnerable to poor eating habits due to demanding…

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Negative / Null Result ReportMedicine

Transverse-plane descriptors and modifiers of the SRS-Lenke-Aubin 3D classification provide complementary and clinically informative 3D features beyond 2D assessment in Lenke 1 AIS curves.

Aubin, Ilharreborde, Lenke et al. · 2026 · Spine deformity

To investigate how the transverse-plane descriptors and modifiers of the SRS-Lenke-Aubin 3D classification-orientation of the regional plane of deformation (ORPD), apical vertebral rotation (AVR), and apical displacement (3D distance from…

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