12,262 real negative results, null findings, and replication failures in Medicine. Search the index →
WASTE indexes published research — it does not host or republish full papers. Each entry is a metadata record compiled from open scholarly databases; the abstract is shown in full only where the paper is openly licensed, otherwise a short excerpt under fair use. Classifications are automated and approximate.
Büyükpolat M, Aydın N, Eryılmaz B et al. · 2025 · BMC oral health
OBJECTIVE: The use of polishing pastes in the final surface preparation of resin composite restorations has become increasingly common. This study aimed to evaluate the effects of polishing pastes containing abrasives of different particle…
View details →Rasmussen MIS, Hansen ML, Pellicer A et al. · 2026 · JAMA pediatrics
Importance Cerebral oximetry monitoring in the first 72 hours after birth has not been shown to reduce death or severe brain injury at 36 weeks' postmenstrual age in extremely preterm infants. The long-term effects remain uncertain.…
View details →Rossi HS, Mykkänen AK, Teppo AM et al. · 2025 · Journal of equine veterinary science
Pneumonia is a common condition in young, hospitalized foals, causing accumulation of inflammatory secretions to the airways. In humans, respiratory physiotherapy is commonly used as a supplementary treatment for pneumonia with varying…
View details →Suvorov VV, Sayitkuliev DB · 2026 · Diseases (Basel, Switzerland)
The development of sternal infection in neonates after cardiac defect correction using median sternotomy is a serious complication, increasing the length of hospital stay, mortality, and treatment costs. One effective method for preventing…
View details →de Lima Cruz GF, Pereira OG, Alves WS et al. · 2025 · Tropical animal health and production
Tropical grasses are widely used for silage, but their high fiber content and variable quality often limit ruminal degradation and animal performance. Strategies such as optimizing regrowth age (RA) and applying fibrolytic enzymes may help…
View details →Sadeghi M, Shahrooz S, Aghamohammadi M et al. · 2025 · BMC research notes
Objective Asthma is a common multifactorial inflammatory disease affecting both children and adults. Various cells and cytokines contribute to this inflammatory process. Smooth muscle contraction, vascular congestion, and airway edema lead…
View details →Pan X, Sarker S, Yu JJ et al. · 2026 · Insects
High rates of pest infestations are frequently reported in low-income homes in the U.S. However, even with access to effective insecticides, most residents are unaware of how to properly control indoor pests. We designed and evaluated the…
View details →Kass C, Katz-Greenberg G, Bodner J et al. · 2025 · Transplant immunology
Purpose Belatacept has been associated with less de novo specific antibody (dnDSA) development, but few publications have compared the incidence of dnDSA development between tacrolimus and belatacept-based immunosuppression regimens. The…
View details →Zhang Y, Pan J, Hou J et al. · 2025 · Medicine
Rationale Asthenozoospermia (AZS), a leading cause of male infertility, frequently results from genetic defects that disrupt flagellar assembly. Mutations in the DNAH11 gene can cause abnormal dynein arm structures, leading to AZS and…
View details →Masri A, Tully TN, Como K et al. · 2025 · Journal of avian medicine and surgery
Euthanasia is a common veterinary medical procedure performed on terminally ill backyard chickens ( Gallus gallus domesticus ). To reduce stress for these animals, it is important to develop a euthanasia protocol that provides a rapid and…
View details →Lee JH, Hwang K, Jeong WK · 2026 · Clinics in orthopedic surgery
Background Arthroscopic rotator cuff repair is widely performed; yet tendon healing failure still occurs in some cases and remains a challenge. To address this issue, several studies have investigated intraoperative injection or patch…
View details →Cuadrado C, Breedlove C, Toro H · 2025 · Avian diseases
Vaccination with a recombinant Newcastle disease virus (NDV) LaSota (LS) strain expressing Arkansas (Ark) -type infectious bronchitis virus (IBV) spike ectodomain (Se) protein and granulocyte-macrophage colony-stimulating factor (GMCSF)…
View details →Daudi S, Zampelis V, Belfrage O et al. · 2025 · The bone & joint journal
Aims Short, uncemented hip stems might provide a favourable alternative in total hip arthroplasty (THA) by preserving proximal bone mass through reduced strain-adaptive remodelling. We evaluated and compared the migration and…
View details →Gates RS, McCoy K, Stewart J et al. · 2026 · Surgery
Background Timely diagnosis and treatment of primary hyperparathyroidism requires a high index of suspicion and collaboration across specialties. The diagnosis often is overlooked. This study aimed to determine whether the introduction of…
View details →Busanello A, Koller OG, Menezes VM et al. · 2025 · The British journal of nutrition
The objective of this study was to evaluate the impact of incorporating group-based nutritional education into usual care on adherence to nutritional counselling among outpatients with type 2 diabetes (T2DM). This parallel-group,…
View details →Williams KG, Constantine EP, Whitney KE et al. · 2026 · Knee surgery, sports traumatology, arthroscopy : official journal of the ESSKA
Purpose To determine whether patients undergoing arthroscopic partial meniscectomy (APM) with synovitis treated by synovectomy exhibit similar outcomes to those without synovitis after 24-month follow-up. Methods A total of 181 patients…
View details →Lopresti AL, Smith SJ · 2025 · Clinical drug investigation
Background and objectives Bacopa monnieri is a plant used in Ayurvedic medicine with traditional uses for memory and cognitive function. The objective of this study was to examine the effects of supplementation with a Bacopa monnieri…
View details →Timmermans J, Van Goethem B, Stock E et al. · 2026 · Veterinary surgery : VS
Objective To evaluate the soft palate thickness in brachycephalic dogs 3 months after performing folded flap palatoplasty (FFP) or standard staphylectomy (STS). Study design Prospective, observational study. Animals Twenty client-owned…
View details →Foddai M, Carter CG, Wood AT et al. · 2025 · Comparative Biochemistry and Physiology, Part A
Sustained aerobic training is suggested to enhance cardiac performance and growth in farmed salmonids, but its effects under suboptimum elevated temperatures remain unclear. This study examined whether continuous training at different…
View details →Pulikova EP, Kotsarev VI, Demin KA et al. · 2025 · Journal of environmental management
Polycyclic aromatic hydrocarbons (PAHs) are one of the most widespread organic pollutants. The methods to restore the natural environments contaminated with these substances include bioremediation based on PAH-degrading microorganisms. In…
View details →Blomberg M, Schaper R, Bonabi A et al. · 2025 · Behaviour research and therapy
Background Effective treatments for anorexia nervosa (AN) are available, yet many patients do not respond to treatment or experience relapse. Cognitive bias modification aims to ameliorate cognitive biases that are assumed to contribute to…
View details →Lorigan P, Medina TM, Nyakas M et al. · 2026 · European journal of cancer (Oxford, England : 1990)
Purpose Immune checkpoint inhibitor (ICI) combinations have improved outcomes in patients with advanced melanoma; however, long term survival remains poor. The addition of therapeutic cancer vaccines to ICI combinations represents a…
View details →Steen L, Javed H, Contorno E et al. · 2025 · Transplantation proceedings
Objective The cornerstone of immunosuppression for transplantation is tacrolimus. One of the most reliable routes for administering tacrolimus in porcine models is intramuscular injection. However, the pharmacokinetics of intramuscular…
View details →Simon S, Shanmugalingam T, Neu T et al. · 2025 · European journal of pharmaceutical sciences : official journal of the European Federation for Pharmaceutical Sciences
Active efflux transporters can play a substantial role in the drug disposition of their substrates in the human body. Efflux transporters like P-glycoprotein (P-gp), multidrug resistance associated protein 1 (MRP1) and breast cancer…
View details →DE Souza GC, Araujo Filho HB, DE Oliveira CZ et al. · 2025 · Arquivos de gastroenterologia
Background Chemotherapy-induced diarrhea is a common and distressing side effect experienced by patients undergoing cancer treatment, particularly those with gastrointestinal cancer. It can lead to significant health complications,…
View details →López-Campos Ó, Chabot B, Attema HR et al. · 2025 · Meat Science.
The effect of localized low voltage electrical stimulation (LVES, 45 V) on meat quality and palatability of the longissimus thoracis et lumborum (LTL) and semitendinosus (ST) was evaluated in this study. There were stimulation method ×…
View details →Modica V, Glávits R, Clewell A et al. · 2025 · International journal of toxicology
Anaerostipes caccae CLB101 (CLB101) is an obligate, anaerobic bacteria that was isolated from the stool of a healthy infant. Due to its ability to produce butyrate and its potential promotion of microbiome health through multiple…
View details →Miravalles C, Kane R, Rossier AT et al. · 2026 · Journal of affective disorders
Background Current treatments for depressive episodes in bipolar disorder are often limited by partial efficacy or delayed therapeutic response. Intravenous scopolamine, a pan-muscarinic antagonist, has shown rapid antidepressant effects…
View details →Grote A, Genther-Schroeder O, Wilson BK et al. · 2025 · Applied Animal Science
Our objective was to determine the effect of plane of nutrition through 92 d of age on subsequent finishing performance, feed efficiency, and carcass characteristics in beef × dairy crossbred steers. Beef × dairy crossbred steers (n = 109)…
View details →Gündüz N, Duran M, Erdal AI et al. · 2026 · The Journal of craniofacial surgery
Facial fractures are a significant aspect of pediatric trauma cases. The impact of intermaxillary fixation (IMF) using screws on dental development, particularly in pediatric patients undergoing primary and mixed dentition, remains a…
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