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Browse the failure-mode index

12,260 real negative results, null findings, and replication failures in Medicine. Search the index →

WASTE indexes published research — it does not host or republish full papers. Each entry is a metadata record compiled from open scholarly databases; the abstract is shown in full only where the paper is openly licensed, otherwise a short excerpt under fair use. Classifications are automated and approximate.

Negative / Null Result ReportMedicine

Does Red Cell Distribution Width Have a Predictive Role in Anastomotic Leak after Right Hemicolectomy for Colon Cancer?

Sevik HO, Aytepe O, Kilic MK et al. · 2026 · Journal of laparoendoscopic & advanced surgical techniques. Part A

Introduction Red cell distribution width (RDW) has recently emerged as a potential biomarker reflecting nutritional and inflammatory status in surgical oncology. While anastomotic leakage (AL) remains a devastating complication after right…

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Negative / Null Result ReportMedicine

Prolonged Mismatch Negativity Latencies in Intensive Care Unit Patients With Active Delirium.

Chen YC, Chang HJ, Chang CW et al. · 2026 · Journal of clinical neurophysiology : official publication of the American Electroencephalographic Society

Introduction Delirium is a common and serious complication in critically ill patients, associated with higher mortality, prolonged intensive care unit (ICU) stays, and cognitive impairments. Furthermore, renal dysfunction is a…

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Negative / Null Result ReportMedicine

Clinical outcomes and haemodynamic response after blinded stress assessment of moderate aortic stenosis.

Eerdekens R, Johnson NP, Adrichem R et al. · 2026 · EuroIntervention : journal of EuroPCR in collaboration with the Working Group on Interventional Cardiology of the European Society of Cardiology

Background Assessing aortic stenosis (AS) haemodynamics under stress may distinguish physiological responses beyond traditional severity metrics. Aims We aimed to evaluate symptomatic patients with moderate AS and preserved left…

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Negative / Null Result ReportMedicine

Temperature at admission and mortality in older adults with infection: Limited prognostic value in non-sepsis cases.

Nielsen FE, Abdullah OB, Chafranska L et al. · 2026 · The American journal of emergency medicine

Background Temperature abnormalities are established prognostic markers in sepsis, but their predictive value in older adults with infection without sepsis remains unclear. Objective To examine the association between arrival temperature…

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Negative / Null Result ReportMedicine

The impact of exposure to additional languages and cognitive factors on narrative macrostructure in autistic and neurotypical children.

Wolfer P, Tselekidou F, Baumeister F et al. · 2026 · Journal of communication disorders

This study adopts a twofold approach to examine how bilingual exposure and (socio-)cognitive factors influence narrative macrostructure in children. First, it investigated the impact of Exposure to Additional Languages (EtAL) on the…

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Negative / Null Result ReportMedicine

Forecasting Local Surges in COVID-19 Hospitalizations through Adaptive Decision Tree Classifiers.

Murray-Watson RE, Guaracha X, Bilinski A et al. · 2026 · Medical decision making : an international journal of the Society for Medical Decision Making

IntroductionDuring the COVID-19 pandemic, many communities across the United States experienced surges in hospitalizations, which strained the local hospital capacity. Some risk metrics, such as the Center for Disease Control and…

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Negative / Null Result ReportMedicine

Usefulness of uric acid-to-high-density lipoprotein cholesterol ratio for the evaluation of insulin resistance in healthy normoglycaemic and normoinsulinaemic men.

Kaneva AM, Bojko ER · 2026 · Experimental and clinical endocrinology & diabetes : official journal, German Society of Endocrinology [and] German Diabetes Association

Uric acid-to-high-density lipoprotein cholesterol ratio (UHR) is a novel and promising marker for metabolic abnormalities. Recent studies have demonstrated that UHR is related to a number of diseases that are caused by insulin resistance.…

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Negative / Null Result ReportMedicine

What works for whom in outpatient cognitive-behavioral therapy? Integration of techniques from different therapeutic orientations and their interactions as predictors of treatment outcome in different diagnostic groups.

van Alebeek H, D'Errico L, Delgadillo J et al. · 2026 · Journal of consulting and clinical psychology

Objective The mechanisms underlying psychotherapy's effects remain debated, with some emphasizing theory-specific therapeutic techniques and others highlighting common factors like therapeutic alliance. Evidence is inconclusive partially…

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Negative / Null Result ReportMedicine

Container Mosquito Abundance in Brooklyn Community Gardens.

Kelley AT, Boger R · 2025 · EcoHealth

Community gardens in urban Brooklyn, New York are social spaces that provide food sovereignty to many New Yorkers, but the arrival of the mosquito Aedes albopictus and longtime presence of Culex pipiens makes socializing in these spaces…

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Negative / Null Result ReportMedicine

Views of aging and symptoms of posttraumatic stress disorder among older adult war veterans in the context of renewed war.

Avidor S, Shenkman G, Shrira A et al. · 2026 · The journals of gerontology. Series B, Psychological sciences and social sciences

Objectives For aging combat veterans, experiencing renewed war in old age can exacerbate coping with age-related challenges. The present study sought to examine how past and current war-related stressors affect long-term trajectories of…

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Negative / Null Result ReportMedicine

Does earlier mobilization reduce venous thromboembolism after spine surgery?

Ng MK, Mathew J, Dalton J et al. · 2026 · European spine journal : official publication of the European Spine Society, the European Spinal Deformity Society, and the European Section of the Cervical Spine Research Society

PURPOSE: Venous thromboembolism (VTE) is an uncommon but potentially devastating complication following spine surgery. Although early mobilization is encouraged as a preventive measure, the influence of inpatient physical therapy on VTE…

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Negative / Null Result ReportOpen accessMedicine

Childhood Linear Growth and Early Morbidity as Predictors of Adolescent Cognitive Ability in Malawi: A Prospective Observational Study.

Videman K, Leppänen JM, Hallamaa L et al. · 2026 · Acta paediatrica (Oslo, Norway : 1992)

Aim Growth faltering and loss of development potential are common in low- and middle-income countries. We aimed to study whether linear growth before and after 2 years, height-for-age Z-score (HAZ) from 1 month until 13 years and morbidity…

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