12,380 real negative results, null findings, and replication failures in Medicine. Search the index →
WASTE indexes published research — it does not host or republish full papers. Each entry is a metadata record compiled from open scholarly databases; the abstract is shown in full only where the paper is openly licensed, otherwise a short excerpt under fair use. Classifications are automated and approximate.
Aung T, Cheah JX · 2025 · Cureus
Livedoid vasculopathy (LV) is a rare, chronic occlusive dermopathy causing recurrent painful ulcerations, impaired healing, and significant morbidity. Historically considered a thrombotic microangiopathy, emerging evidence suggests an…
View details →Ayusso LL, Girol AP, Ribeiro Souza H et al. · 2024 · Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie
We assessed in vivo the protective effects and underlying antioxidant and anti-inflammatory properties of dry green tee extract (GTE) on glomerular and tubular kidney function and structure in an experimental model of gentamicin…
View details →de Lazzari E, Nomah DK, Blanco JL et al. · 2024 · International journal of infectious diseases : IJID : official publication of the International Society for Infectious Diseases
Objectives The prevalence and risk factors of SARS-CoV-2 infection among unvaccinated people living with HIV (PWH) are not well understood, and the protective role of tenofovir remains controversial. This study aimed to assess the…
View details →Gabaldon-Albero A, Martin-Grau C, Marti-Masanet M et al. · 2024 · Pediatric rheumatology online journal
Background Aicardi-Goutières Syndrome is a monogenic type 1 interferonopathy with infantile onset, characterized by a variable degree of neurological damage. Approximately 7% of Aicardi-Goutières Syndrome cases are caused by pathogenic…
View details →Tang F, Zhang L, Lu S et al. · 2026 · Cancer reports (Hoboken, N.J.)
Background Hyperbaric oxygen therapy (HBOT) is widely used as a therapeutic intervention for various types of wounds. Studies have shown that in addition to improving local oxygen supply to the wound site, HBOT can also influence cytokine…
View details →Gao J, Mathias RT, Varadaraj K et al. · 2025 · Investigative ophthalmology & visual science
Purpose The lens has a feedback control system made by transient receptor potential vanilloid 4 (TRPV4) and TRPV1 to sense pressure and activate ion transport to maintain intracellular hydrostatic pressure close to zero at the lens…
View details →Cropper E, Riley P, Simon AG · 2024 · Journal of forensic sciences
There are many factors that may affect the longevity of or guide the use of canine training aids. Literature to date has mainly focused on identifying the headspace volatiles associated with training aids or odors and only minimal research…
View details →Carr JF, Basurto De Santiago C, Bhut SA et al. · 2026 · mBio
In gram-negative bacteria, the outer membrane (OM) acts in conjunction with the peptidoglycan (PG) cell wall as a barrier against physical, osmotic, and chemical environmental stressors, including antibiotics. SanA, an inner membrane…
View details →Bastia L, Garberi R, Querci L et al. · 2024 · Journal of clinical monitoring and computing
To determine how percutaneous tracheostomy (PT) impacts on respiratory system compliance (C rs ) and end-expiratory lung volume (EELV) during volume control ventilation and to test whether a recruitment maneuver (RM) at the end of PT may…
View details →Nemets VV, Grinevich VP, Petrunina EN et al. · 2025 · Cells
Recent studies indicated a connection between trace amine-associated receptor 5 (TAAR5) and emotional behaviors related to anxiety and depression; however, the neurobiological basis of this link is still unclear. Using mutant TAAR5…
View details →Yurttutan S, Geçkil E · 2026 · Journal of pediatric nursing
Aim This study aimed to evaluate the effects of a Mindfulness-Based Stress Reduction (MBSR) program on depression, anxiety, stress, and hopelessness among parents of children with autism (Autism Spectrum Disorder [ASD]). Method A…
View details →Çelik I, Sarıçoban C · 2023 · British poultry science
1. The aim of this study was to utilise low-value spent hen meat and investigate the possibility of using chia (Salvia hispanica L.) as a mucilage-based edible film to prevent loss of quality in meat products. For this purpose, spent hen…
View details →Baghdadi MA, do Carmo Las Casas PHF, Mbemba E et al. · 2026 · Cancers
Background/Objectives : Tissue factor (TF)-expressing cancer cells and their extracellular vesicles (CaCe-dEVs) are key drivers of cancer-associated hypercoagulability and vascular dysfunction. While low-molecular-weight heparins (LMWHs)…
View details →Ahmed Eltayeb S, Dressler JM, Schlatt L et al. · 2024 · Archives of toxicology
Oxaliplatin (OHP) is effective in colorectal cancer treatment but induces peripheral neurotoxicity (OHP-induced peripheral neurotoxicity, OIPN), diminishing survivor quality of life. Organic cation transporter 2 (OCT2) is a key OHP uptake…
View details →Martindale DM, Haraschak JL, Thiel AJ et al. · 2024 · Journal of veterinary emergency and critical care (San Antonio, Tex. : 2001)
Objective To describe the presentation, management, and postmortem examination findings in a dog with confirmed lisdexamfetamine dimesylate (LDX) toxicosis. Case summary A 3-year-old female neutered mixed breed dog initially presented with…
View details →Nasir S, Mehfooz S, Basu S et al. · 2025 · Taiwan journal of ophthalmology
Purpose Rhegmatogenous retinal detachments (RRD) are the most common and sight-threatening complication of acute retinal necrosis (ARN). This study aims to analyze the clinical characteristics, treatment outcomes, and factors influencing…
View details →Lee CT, Tran D, Tsukiboshi Y et al. · 2023 · Journal of clinical periodontology
Aim This randomized controlled trial aimed to investigate the efficacy of soft-tissue augmentation (STA) with a subepithelial connective tissue graft (SCTG) or an acellular dermal matrix (ADM) on reducing tissue alterations at an immediate…
View details →Hansen RH, Rölfing JD, Nielsen CL et al. · 2023 · Journal of clinical medicine
Intertrochanteric femoral fractures are commonly treated with intramedullary nails (IMNs). A tip-apex distance (TAD) of more than 20-25 mm is associated with an increased risk of cut-out. The Stryker Adaptive Positioning System (ADAPT) is…
View details →Neubauer HR, Ogunyemi IM, Wood AK et al. · 2026 · Infection and immunity
Clostridioides difficile and vancomycin-resistant Enterococcus faecium (VRE) are commonly co-isolated from hospitalized patients. We sought to develop a co-culture biofilm model to characterize interactions between these two opportunistic…
View details →Takemura K, Murakawa Y, Kono H et al. · 2026 · Case reports in oncology
Introduction Fruquintinib is a selective vascular endothelial growth factor receptor inhibitor approved for metastatic colorectal cancer (mCRC) that is refractory to standard therapies. While its efficacy and safety have been demonstrated…
View details →Matta G, Edwards A, Roelands B et al. · 2026 · Research quarterly for exercise and sport
The physiological and placebo effects of beetroot juice remain unclear in settings outside traditional laboratory environments. Using a randomized, between-participant balanced placebo design, we asked 67 trained cyclists to complete…
View details →Pokhrel P, Phillips KT, Phillips MM et al. · 2026 · Addiction (Abingdon, England)
Background and aims Co-use of cannabis and e-cigarettes for nicotine is increasing among younger adults in the United States (US). This study aimed to determine (1) the patterns of cannabis and e-cigarette use and co-use over time and (2)…
View details →Fiebig N, Bartsch L, Klötzer C et al. · 2026 · Headache
Objective To evaluate the effects of a short, structured multimodal day-clinic program on health-related quality of life and disability in patients with primary headache disorders. Background Although monoclonal antibodies targeting the…
View details →Jean J, Klein JI, Karashchuk N et al. · 2026 · Headache
Objective To determine if there is increased headache burden and disability among women with and without migraine during an in vitro fertilization (IVF) cycle. Background Migraine and infertility commonly impact women of childbearing age.…
View details →Arko L, Nguyen TH, Stoffel M et al. · 2026 · AMIA Joint Summits on Translational Science proceedings. AMIA Joint Summits on Translational Science
Documentation burden and cognitive load contribute to clinician burnout, and ambient AI scribes offer a promising solution, though real-world evaluations remain limited. This study evaluated the impact of an ambient AI scribe on…
View details →Gambale C, Faranda A, Ambrogio A et al. · 2026 · European journal of endocrinology
Objective Several patients with medullary thyroid carcinoma (MTC) are not cured after surgery. Disease persistence/recurrence is monitored by measuring calcitonin (CTN) and carcinoembryonic antigen (CEA) and by imaging. The role of…
View details →Zhang W, Guh DP, Tam ACT et al. · 2026 · Health affairs scholar
Introduction Evidence on the launch and diffusion of therapeutically important new medicines is limited. We examined the launch and diffusion of new patented medicines in 14 countries by therapeutic value. Methods We analyzed IQVIA MIDAS®…
View details →Yılmaz NA, Caner İ · 2026 · BMC medical education
Innovative educational strategies are increasingly needed in physiotherapy education to support students' learning and professional development. Game-based learning (GBL) is an interactive, student-centered approach that may enhance…
View details →Schwab ME, Stottlemyre R, Khan FA · 2026 · Journal of pediatric surgery
Purpose In patients with congenital lung malformations (CLM), prenatal imaging is used to risk stratify patients and delineate algorithms for delivery planning and neonatal care. Most algorithms include a chest x-ray immediately after…
View details →Ziraldo ER, Yang Y, Arcand J et al. · 2026 · Public health nutrition
Objectives To assess changes in (1) Na content of processed foods in the Canadian food supply and (2) the proportion of products meeting Health Canada's voluntary Na reduction targets (SRT) between 2010 and 2020. Design This repeated,…
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