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Browse the failure-mode index

12,254 real negative results, null findings, and replication failures in Medicine. Search the index →

WASTE indexes published research — it does not host or republish full papers. Each entry is a metadata record compiled from open scholarly databases; the abstract is shown in full only where the paper is openly licensed, otherwise a short excerpt under fair use. Classifications are automated and approximate.

Negative / Null Result ReportMedicine

Changing the narrative: stories reduce biases against anomalous faces.

Bilici N, Paruzel-Czachura M, Workman CI et al. · 2026 · BMC psychology

Facial anomalies, such as scars, are often linked to an "anomalous-is-bad" stereotype, in which people with visible differences are seen as less warm or less moral. We developed the "Normalizing Anomalies with Mobile Exposure" (NAME)…

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Negative / Null Result ReportMedicine

Randomized controlled trial of Understanding Social Situations versus problem-solving training in improving social function in people with psychosis.

Fiszdon JM, Wang K, Fulford D et al. · 2026 · Journal of the International Neuropsychological Society : JINS

Objectives Poor social function in people with psychosis has been linked to impairments in social cognition and neurocognition, which in turn have been identified as promising treatment targets. We developed a novel social cognitive…

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Negative / Null Result ReportMedicine

Changes in corneal astigmatism, axial length and anterior chamber depth after vitrectomy and phacovitrectomy in rhegmatogenous retinal detachment.

Liu N, Zhao J, Wu B et al. · 2026 · International ophthalmology

Purpose To evaluate the changes in corneal astigmatism, axial length and anterior chamber depth following vitrectomy versus phacovitrectomy in patients with rhegmatogenous retinal detachment (RRD) under more detail group.To discuss how to…

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Negative / Null Result ReportMedicine

A Virtual Tai Chi Intervention for Older Adults with Mobility Disabilities: Results from a Single-Arm Clinical Trial with the TechSAge Tele Tai Chi Program.

Mitzner TL, Remillard ET, Mumma KT et al. · 2026 · Healthcare (Basel, Switzerland)

Background/Objectives : Telewellness programs can expand access to exercise and social opportunities for older adults, especially those with mobility disabilities. The TechSAge Tele Tai Chi clinical trial assessed whether the Tai Chi for…

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Negative / Null Result ReportMedicine

Experience With Performing Rheocarna Therapy via the Single-Needle Method for Treatment of Chronic Limb-Threatening Ischemia.

Yamauchi Y, Tanaka R, Kawahira R et al. · 2026 · Therapeutic apheresis and dialysis : official peer-reviewed journal of the International Society for Apheresis, the Japanese Society for Apheresis, the Japanese Society for Dialysis Therapy

Introduction This study investigated the safety and efficacy of single-needle Rheocarna therapy for chronic limb-threatening ischemia (CLTI) with wounds. Methods Six patients with CLTI involving ulcers unresponsive to revascularization…

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Negative / Null Result ReportMedicine

Effects of High-Impact Exercise on Bone Marker Concentrations During Controlled Low Energy Availability in Recreational Female Runners.

Sterringer T, Sale C, Morozov A et al. · 2026 · Calcified tissue international

Exposure to low energy availability (LEA) can stimulate metabolic adaptations that have been shown to disrupt bone remodeling as suggested by suppressed markers of bone formation and/or increased markers of bone resorption. Previous…

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Negative / Null Result ReportMedicine

Observation of Altered Iron Status Development During Noncompetitive Season Training in NCAA Division I Female Acrobatics and Tumbling Athletes.

Pickler MC, Funderburk LK, Lee KM et al. · 2026 · Journal of strength and conditioning research

Abstract Pickler, MC, Funderburk, LK, Lee, KM, Bolden, LK, Chapman-Lopez, TJ, Heileson, JL, and Gallucci, AR. Observation of altered iron status development during noncompetitive season training in NCAA Division I female acrobatics &…

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Negative / Null Result ReportMedicine

Voice and Swallowing in Professional Voice Users: The Effect of Therapy Methods.

Özcan Ulubeli P, Aydoğan Z, Karakaya Gojayev E et al. · 2026 · Folia phoniatrica et logopaedica : official organ of the International Association of Logopedics and Phoniatrics (IALP)

Introduction This study aimed to evaluate pain complaints, as well as voice and swallowing functions, in professional voice users, and to compare the effectiveness of three therapeutic approaches: vocal hygiene (VH), vocal function…

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Negative / Null Result ReportMedicine

Quantitative and Comparative Analysis of Dream Content in Parkinson's Disease Patients Undergoing Deep Brain Stimulation: A Pilot Study.

Joswig H, Oreizi-Esfahani S, Medack S et al. · 2026 · World neurosurgery

Background Parkinson's disease (PD) is a neurodegenerative disorder characterized by the loss of dopaminergic neurons in the substantia nigra, resulting in motor and nonmotor symptoms including diminished sleep quality and altered dream…

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Negative / Null Result ReportMedicine

Psychopathological correlates of early childhood sleep terror: associations with nutritional biomarkers, behavioral dysregulation, and sleep disturbance.

Esen Öksüzoğlu M, Kabukçu HO · 2026 · BMC psychiatry

Background Sleep terror (ST) is a common NREM parasomnia in early childhood and may be associated with broader emotional and behavioral dysregulation. However, its links with psychopathological symptoms and nutritional biomarkers remain…

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Negative / Null Result ReportMedicine

Airway Mucus Occlusions in Ex-Smokers with and Without COPD.

Tcherner S, Durom E, Peters J et al. · 2026 · COPD

In patients with moderate-to-severe COPD, airway mucus-occlusions correlate with airflow limitation, exacerbation and mortality-risk. However, the clinical relevance of mucus-plugs in milder COPD is not well-understood. We evaluated…

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Negative / Null Result ReportMedicine

The Effect of Pessary Insertion on Pelvic Anatomy: A Prospective Observational Study Using Upright MRI.

Steen AV, Simmering JA, Perik M et al. · 2026 · BJOG : an international journal of obstetrics and gynaecology

Objective To determine the anatomical effect of pessaries in the upright position in women with pelvic organ prolapse (POP). Design Prospective observational cohort study. Setting Outpatient clinic of our gynaecology department. Population…

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Negative / Null Result ReportMedicine

Potential usefulness of [123I]I-MIBG SPECT/CT with AC Quant protocols in diagnostics and treatment monitoring of children with neuroblastoma.

Śliwińska A, Świtaj K, Durma AD · 2026 · Nuclear medicine review. Central & Eastern Europe

Background Neuroblastoma (NB) is the most common extracranial solid tumor in children. Metaiodobenzylguanidine (MIBG) selectively accumulates in adrenergic tissue, enabling its use for diagnostic imaging of NB. The implementation of new…

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Negative / Null Result ReportMedicine

Driving Cerebellar Theta Oscillations Interferes With Voluntary Neck Movements in Cervical Dystonia.

Costa D, Guerra A, Birreci D et al. · 2026 · Movement disorders : official journal of the Movement Disorder Society

Background Cervical dystonia (CD) is a movement disorder with a complex pathophysiology, including cerebellar abnormalities. Transcranial alternating current stimulation (tACS), a noninvasive neuromodulation technique capable of entraining…

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