12,380 real negative results, null findings, and replication failures in Medicine. Search the index →
WASTE indexes published research — it does not host or republish full papers. Each entry is a metadata record compiled from open scholarly databases; the abstract is shown in full only where the paper is openly licensed, otherwise a short excerpt under fair use. Classifications are automated and approximate.
Kemp LT, Smeets T, Jansen A et al. · 2026 · Journal of behavior therapy and experimental psychiatry
While studying appetitive and aversive conditioning is common in psychopathology research, studies that measure both types of learning simultaneously are rare. To gain insight into the role of appetitive and aversive learning in the…
View details →Del Grosso SJ, Nichols KL, Delgado JA et al. · 2025 · Nutrient cycling in agroecosystems.
Grassland soils managed with livestock grazing can act as sources and sinks for methane (CH₄) and nitrous oxide (N₂O), but, in aggregate, are typically a source of N₂O and a sink for CH₄. Previously, we observed higher N₂O losses from…
View details →Arriero-Cabañero A, Díaz-Rubio N, Talabán-Rocha C et al. · 2025 · Molecular neurobiology
Pyruvate kinases are key enzymes of glycolytic metabolism of neurons and glia. One of them, pyruvate kinase M2 (PKM2) can also act as a transcriptional regulator and in this function has been implicated in several neurodegenerative…
View details →Moreau AL, Rappaport BI, Saturday ML et al. · 2026 · Journal of psychiatric research
Intolerance of uncertainty (IU) is an individual difference dimension reflecting negative cognitive, emotional, and behavioral responses to uncertainty. IU is an important etiological and maintaining mechanism of internalizing…
View details →Elster A, Ron L · 2026 · Journal of personality
Introduction Behavior is not solely determined by individual dispositions or situational demands, but by the dynamic interplay between them. The current research investigates the contextual sensitivity of behavioral determinants by…
View details →Ye J, Hoàng DĐ, Liu X et al. · 2025 · Biochemical and Biophysical Research Communications
Schisandrin B (SchB), a natural lignan with reported organ-protective effects, was hypothesized to ameliorate severe acute pancreatitis (SAP). We investigated the effects of SchB (30 and 60 mg/kg) in a caerulein-induced mouse model of SAP…
View details →Raidl P, Vogl A, Dreisörner A et al. · 2026 · Psychophysiology
Prior evidence suggests that individuals with higher fitness exhibit attenuated endocrine and autonomic responses to acute psychological and physical stressors. However, it remains unclear whether this stress-buffering effect depends on…
View details →Varden Gjerde K, Bartz-Johannessen C, Løberg EM et al. · 2026 · Schizophrenia research
Background Schizophrenia patho-etiology may involve endothelial inflammation and blood-brain barrier (BBB) dysregulation with cellular adhesion molecules (CAMs) as important mediators. CAMs are essential for cellular integrity but can show…
View details →Chhabra BR, Madan AK, Tichansky DS · 2025 · Cureus
Introduction Relationships with industry may create a potential conflict of interest (COI). Disclosure of COI is essential for integrity of educational programming. In 2013, Center for Medicare and Medicaid Services (CMS) developed the…
View details →Weerakoon SM, Henson-Garcia M, Rose R et al. · 2025 · Community health equity research & policy
BackgroundBlack and Latinx youth are disproportionately exposed to neighborhood violence and related mental health challenges. Racial-ethnic identity shapes how adolescents perceive, interpret, and cope with stressful environmental…
View details →van Witteloostuijn M, Blom E · 2025 · Journal of communication disorders
Multilingual children naturally encounter language mixing in their environment. Since children's language development depends on their language input, and processing language mixing in the input may be cognitively demanding, the amount of…
View details →Pizzolla E, Fiorio M, Marotta A et al. · 2026 · Quarterly journal of experimental psychology (2006)
Fatigue has a profound impact on various sensory and perceptual processes; yet, its effects differ depending on whether it arises from physical or mental exertion. While physical fatigue is known to alter body weight perception, it remains…
View details →Traylor DA, Nunes EA, Lees MJ et al. · 2026 · Health science reports
Background and aim Testosterone is an important hormone in male physiology, playing a key role in reproductive function, muscle growth, bone mineral density, and metabolic regulation. Cold exposure is celebrated in fitness and wellness…
View details →Ye J, Huang Y, Liu X et al. · 2025 · Biochemical and biophysical research communications
Schisandrin B (SchB), a natural lignan with reported organ-protective effects, was hypothesized to ameliorate severe acute pancreatitis (SAP). We investigated the effects of SchB (30 and 60 mg/kg) in a caerulein-induced mouse model of SAP…
View details →Magura T, Mizser S, Horváth R et al. · 2026 · Insects
Urbanization is a major and rapidly expanding form of land-use change worldwide and is one of the main drivers of the decline in arthropod diversity. Within urban matrices, remnants of natural or semi-natural habitats serve as important…
View details →Frish Simcovich Y, Eigner E, Joskowicz L et al. · 2026 · The Journal of hand surgery, European volume
We examined the correlations between the surface morphology of acute scaphoid fractures and their stability. Our hypothesis was that a more irregular fracture surface would have a stabilizing effect on the fracture. A total of 75 isolated…
View details →Li YC, Lemaire KK, Bruijn SM et al. · 2025 · Neuroscience
Walking without falling requires correcting the deviations of the centre of mass (CoM) trajectory relative to the base of support. This process is partially under feedback control. We investigated whether vestibular afference contributes…
View details →Brink KJ, Wiles TM, Stergiou N et al. · 2025 · Human movement science
The Optimal Movement Variability Hypothesis posits that healthy movements exhibit an optimal structure of variability, characterized by fractal patterns, which confer both stability and flexibility in motor control. This optimal,…
View details →Weber RE, Schulze KM, Kenney NJ et al. · 2025 · American journal of cancer research
Breast cancer patients' maximal O 2 uptake (V̇O 2 max) values average 60-80% of age-predicted values which is often attributed to adjuvant therapy rather than risk factors, comorbidities, or the tumor and associated factors (e.g.,…
View details →Erickson MG, Reinhardt LA, Svaren L et al. · 2024 · Journal of dairy science
Reducing dietary CP is a well-established means to improve N use efficiency. Yet, few studies have considered if transient restrictions in dietary CP could reduce the environmental footprint of late-lactation cows. We hypothesized that the…
View details →Colomer-Poveda D, Mera-González I, Marcos-Frutos D et al. · 2026 · European journal of applied physiology
PURPOSE: The aim of this triple-blind, placebo-controlled study was to determine the effects of anodal transcranial direct current stimulation (a-tDCS) applied over the primary motor cortex (M1) and the dorsolateral prefrontal cortex…
View details →Agir M, Sahin K, Pulatkan A et al. · 2026 · JSES international
Background Rotator cuff tears are a leading cause of shoulder pain, with high rerupture rates despite advancements in surgical techniques. Tendon-to-bone healing failure is often attributed to insufficient fibrocartilage regeneration at…
View details →Meier K, van Hoeken D, Kager CCM et al. · 2025 · The International journal of eating disorders
Objective This study examined the impact of the COVID-19 pandemic on incidence rates of anorexia nervosa (AN) and bulimia nervosa (BN) in Dutch primary care by comparing pre-pandemic (2015-2019) and in-pandemic (2020-2022) periods. We…
View details →Haucke M, Heinz A, Heinzel S et al. · 2025 · European archives of psychiatry and clinical neuroscience
Adverse alcohol consumption is a major public health concern, which might have been further increased by the COVID-19 pandemic. In this study we investigated the impact of a lockdown stage on the association between alcohol consumption,…
View details →Hascher K, Brown R, Janulis P et al. · 2026 · Biopsychosocial science and medicine
Objective Sexual minority (SM) populations experience worse cardiovascular health than heterosexual populations. One potential pathway is the effects of disclosure (sharing) or concealment (withholding) of SM identity due to anticipated…
View details →Kweon J, Ganesh P, Brown JC · 2025 · Transcranial magnetic stimulation (2024)
Health and behavioral factors likely influence repetitive transcranial magnetic stimulation (rTMS) effectiveness, though clear support is lacking. Since habitual caffeine use has been found to impair corticomotor plasticity, we…
View details →Chung YH, Williams LH, Brady TF et al. · 2025 · Journal of experimental psychology. General
Across many studies, verbal labels have been shown to significantly affect perceptual and cognitive processes. Here, we ask whether verbal labels can also improve visual working memory performance by making objects more recognizable. In a…
View details →Popovic D, Reddy YNV, Omar M et al. · 2025 · Mayo Clinic proceedings
Objective Myeloperoxidase (MPO) is a heme peroxidase that scavenges nitric oxide and contributes to microvascular dysfunction. Patients with heart failure and preserved ejection fraction (HFpEF) have microvascular dysfunction that leads to…
View details →Cohen M, Orgel E, Nevarez-Mejia J et al. · 2025 · EJHaem
Introduction Obesity contributes to poorer clinical outcomes in patients with acute lymphoblastic leukemia. We have shown that adipocytes cause anthracycline resistance by absorbing and metabolizing them into less-active alcohol…
View details →Więcławski W, Smus A, Binder M · 2025 · Vision research
Pupillary light response (PLR) is modulated by the allocation of spatial attention. Larger pupil constrictions for bright stimuli presented on the left side are considered indicative of pseudoneglect, a subtle attentional bias observed in…
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