Negative / Null Result ReportOpen accessMedicine
Champion S, Bilton R, Gordon S · 2026 · Australasian journal on ageing
Objectives This study evaluated the outcomes for individuals who completed an Innovator Training Program (ITP) funded by the Commonwealth Government of Australia and delivered by Aged Care Research & Industry Innovation Australia (ARIIA).…
View details →Failed Experiment ReportOpen accessMedicine
Kloc K, Toumi M, Łukomska E et al. · 2026 · Journal of market access & health policy
The Joint Clinical Assessment (JCA) evaluates the relative effectiveness (RE) of interventions over comparators. While randomised control trials (RCTs) are considered the gold standard, single-arm trials (SATs) require an external control…
View details →Null DatasetMedicine
Iqbal U, Manga YB, Nkhoma DE et al. · 2026 · NPJ digital medicine
Digital health interventions (DHIs) are increasingly used to strengthen patient engagement. However, despite its rapid growth, DHIs remain unevenly evaluated and poorly standardized. Six databases were searched to generate an evidence gap…
View details →Methods Dead-EndOpen accessMedicine
Maldonado M, Boedeker P, Kusnoor AV · 2026 · The clinical teacher
Background Management reasoning (MR), the component of clinical reasoning concerned with treatment planning, patient preferences and resource considerations, develops later than diagnostic reasoning and remains underemphasised in medical…
View details →Abandoned HypothesisOpen accessMedicine
Costa T · 2026 · Frontiers in psychology
Across psychology, bold empirical claims often outpace the evidential support on which they rest. The replication crisis has shown that statistical significance alone provides little guidance about what should rationally be believed. To…
View details →Abandoned HypothesisOpen accessMedicine
Werneburg F, Zeh A, Gutteck N et al. · 2026 · Journal of bone and joint infection
Topical intrawound vancomycin powder has been widely adopted in orthopaedic surgery as an adjunct for the prevention of surgical site infection (SSI) and periprosthetic joint infection (PJI). Retrospective cohorts and derived meta-analyses…
View details →Negative / Null Result ReportMedicine
Larvie DY, Güitrón Leal CE, Venkatramanan S et al. · 2026 · The Cochrane database of systematic reviews
Rationale Vitamin B 12 deficiency is an important public health problem in children, and has been associated with anaemia and impaired growth, cognition, and development. Vitamin B 12 deficiency may develop in children due to lower content…
View details →Negative / Null Result ReportOpen accessMedicine
Shu W, Zhou Y, Sun E et al. · 2026 · Journal of medical Internet research
Background Embodied intelligence-artificial intelligence instantiated in physical or virtual bodies that can perceive, communicate, and interact with users and their environments-has been increasingly applied in health care. However, the…
View details →Negative / Null Result ReportMedicine
Scurich N, Albright TD · 2026 · Proceedings of the National Academy of Sciences of the United States of America
Proficiency testing is widely used to assess expertise in medicine, engineering, and other high-stakes fields. In forensic science, such tests are often cited in court as evidence that pattern-comparison methods are accurate and reliable.…
View details →Negative / Null Result ReportMedicine
Stewart JJ, Allen BS, Polutchko SK et al. · 2026 · Journal of experimental botany
Refilling of xylem embolism during recovery from drought has been studied for decades, although the legitimacy of supporting evidence has been debated in recent years due to potentially widespread methodological artifacts associated with…
View details →Negative / Null Result ReportOpen accessMedicine
van der Steege AE, Humuza J, Shyirambere C et al. · 2026 · BMJ global health
Introduction The WHO Model Lists of Essential Medicines (MLEM and MLEMc) guide national medicine selection, particularly in low-income and lower middle-income countries (LMICs). Concerns exist about the adequacy and transferability of…
View details →Negative / Null Result ReportMedicine
Ganguly A, Bhowmik S, Hajra A · 2026 · Therapeutic hypothermia and temperature management
Shivering is a common complication of targeted temperature management (TTM), which could undermine its neuroprotective benefits by increasing cerebral oxygen consumption and metabolic demand. Buspirone, a 5-HT1A receptor partial agonist,…
View details →Negative / Null Result ReportMedicine
Simone J, Cooke C, Lee S et al. · 2026 · Sexually transmitted infections
Congenital syphilis (CS) has been rapidly re-emerging as a public health crisis across North America. The present standard of care treatment for CS involves a 10-day hospitalisation for intravenous penicillin G, which is costly for…
View details →Negative / Null Result ReportMedicine
Jin X, Shen T, Wang Y et al. · 2026 · JBI evidence implementation
Introduction Auditory hallucinations, persistent and distressing symptoms in patients with schizophrenia, are often poorly controlled by antipsychotics. Structured non-pharmacological interventions remain limited in routine clinical…
View details →Negative / Null Result ReportMedicine
Black CFD, Phillips C, Sanders IA et al. · 2026 · Child maltreatment
It is unclear whether research has generated causal evidence about the impact of mandatory reporting (MR) policies on reporting outcomes. This scoping review applied concepts from the NIH Stage Model to map and organize five decades of…
View details →Negative / Null Result ReportMedicine
Gao Y, Liu M, Li L et al. · 2026 · The Cochrane database of systematic reviews
Background Triple-negative breast cancer (TNBC), an aggressive subtype lacking oestrogen and progesterone receptors and amplification of HER2 receptors, accounts for 12% to 17% of breast cancers. Adjuvant and neoadjuvant chemotherapy…
View details →Negative / Null Result ReportMedicine
Brock AS · 2026 · American journal of speech-language pathology
Purpose The objective of this review article is to examine and describe the literature on training speech-language pathology students on the principles of evidence-based practice (EBP). Method A scoping literature review was undertaken in…
View details →Negative / Null Result ReportOpen accessMedicine
Yao S, Xu L · 2026 · Frontiers in medicine
Background Idiopathic granulomatous mastitis (IGM) is a rare chronic inflammatory breast disease characterized by a prolonged clinical course with recurrent episodes, and the optimal treatment remains controversial. Multiple systematic…
View details →Negative / Null Result ReportMedicine
Riestra-Ayora J, Fernández-Navarro C, Martín-Sanz E et al. · 2026 · Diving and hyperbaric medicine
Introduction Fitness-to-dive after otologic surgery is often approached conservatively, with some procedures historically labelled as absolute contraindications despite limited empirical evidence. The available literature is heterogeneous…
View details →Negative / Null Result ReportMedicine
De Santis KK, Matthias K, Nikoyan K et al. · 2026 · Journal of prevention (2022)
Cochrane reviews provide high-quality evidence syntheses. To guide the production and dissemination of new Cochrane reviews, an evidence map based on the characteristics of existing reviews is necessary. This study is a scoping review that…
View details →Negative / Null Result ReportOpen accessMedicine
Yang M, Lovrenert K, Thirumavalavan N et al. · 2026 · Basic and clinical andrology
Background Male infertility affects approximately 10% of men globally, yet approximately 70% of cases lack a definitive genetic diagnosis. Next-generation sequencing has identified numerous monogenic causes, many of which are linked to…
View details →Negative / Null Result ReportMedicine
Hu JX, Wen Q, Zhou H et al. · 2026 · Geriatric nursing (New York, N.Y.)
Objective To systematically synthesize the best available evidence on nonpharmacological interventions in traditional Chinese medicine (TCM) for cognitive impairment in patients with Alzheimer's disease (AD). Methods Guided by the "6S"…
View details →Negative / Null Result ReportMedicine
Belančić A, Rogoznica Pavlović M, Fajkić A et al. · 2026 · Rheumatology international
Obstructive sleep apnoea (OSA) and spondyloarthritis (SpA) are chronic inflammatory disorders associated with substantial cardiometabolic morbidity and impaired quality of life. Increasing evidence suggests that these conditions frequently…
View details →Negative / Null Result ReportMedicine
Gopinath D, On CY, Veettil SK et al. · 2026 · Oral diseases
Background The cumulative evidence from meta-analyses on interventions for oral submucous fibrosis (OSF) remains uncertain in terms of strength, precision, and quality. This umbrella review synthesizes the current evidence on available…
View details →Negative / Null Result ReportOpen accessMedicine
Qiu F, Ling C, Wang S et al. · 2026 · Molecules (Basel, Switzerland)
Mulberrofuran A (MFA), a natural product originally isolated from the root bark of Morus alba L. (Sang-Bai-Pi), is a structurally distinctive mulberry-derived 2-arylbenzofuran bearing a prenyl-related side chain. Although MFA has attracted…
View details →Negative / Null Result ReportOpen accessMedicine
Chauhan V, Goyal D, Thakur S et al. · 2026 · The western journal of emergency medicine
Introduction Organophosphate (OP) poisoning is a significant global health issue, particularly in tropical regions. Despite established treatments such as atropine and oximes, the effectiveness of other interventions remains uncertain.…
View details →Negative / Null Result ReportOpen accessMedicine
Gazit N, Ben-Gal G, Eliashar R · 2026 · JMIR medical education
Background Assessment of technical aptitude, cognitive abilities, and personality characteristics is important in selecting candidates for surgical training. Currently, the selection of surgical training candidates does not systematically…
View details →Negative / Null Result ReportOpen accessMedicine
Du Y, Xu Z, Wen T et al. · 2026 · Diabetes, metabolic syndrome and obesity : targets and therapy
Purpose The care of diabetic foot ulcers (DFU) continues to be a notable clinical challenge. The efficacy and safety of stem cell therapies versus conventional treatments for DFU are debated. Cross-sectional analyses of meta-analyses…
View details →Negative / Null Result ReportOpen accessMedicine
Zhang Y, Wu Z · 2026 · Frontiers in public health
Background Digital technologies in oncology require patients and health workers to possess adequate electronic health literacy (eHealth literacy). Yet, the extent to which this literacy influences cancer-specific insights, ranging from…
View details →Negative / Null Result ReportMedicine
Hou YN, Gubili J, Mao JJ · 2026 · Seminars in radiation oncology
Studies show that patients with cancer use herbal products more often than the general population. Lowering the risk of disease recurrence, symptom control, and improving quality of life are often the reasons cited for such use. However, a…
View details →