Joint Clinical Assessment in the EU HTA Regulation-Would Drugs Supported by Single-Arm Trials Fit Under Evaluation?
Kloc K; Toumi M; Łukomska E; Kowalska M; Tyrała-Chowaniec I; Simoens S; Wasem J; Boyer L · 2026 · Journal of market access & health policy
WASTE classifies this as Failed Experiment Report · AI classification, approximate
An experimental approach did not work as intended — learn what to avoid before investing the same effort.
Abstract (excerpt)
The Joint Clinical Assessment (JCA) evaluates the relative effectiveness (RE) of interventions over comparators. While randomised control trials (RCTs) are considered the gold standard, single-arm trials (SATs) require an external control…
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Metadata source: Europe PMC · DOI 10.3390/jmahp14020036