Failed Experiment ReportMedicine
Hennigar SR, Miller KM, Murphy RD et al. · 2026 · The Journal of nutrition
Background Iron deficiency (ID) is associated with decreased appetite and altered mood, which can contribute to feelings of early satiety and reduced overall well-being. Few studies have examined differences in appetite, satiety, and mood…
View details →Negative / Null Result ReportMedicine
Keskimölö T, Kiviaho A, Karppinen J et al. · 2026 · Aerospace medicine and human performance
Introduction Fighter pilots are exposed to high +Gz forces, helmet-mounted equipment, and extreme head positions that potentially cause cervical spine degeneration and pain. This study aimed to investigate whether individual +Gz exposure,…
View details →Negative / Null Result ReportMedicine
Taymur BD, Toklucu G, Gunkaya OS et al. · 2026 · Journal of the College of Physicians and Surgeons--Pakistan : JCPSP
Objective To evaluate the association between Selenium (Se) and other micronutrients (iron, ferritin, copper, zinc, and vitamin B12) and the development of preeclampsia (PE), and to assess their predictive performance. Study design An…
View details →Negative / Null Result ReportMedicine
Szabóová S, Duraníková O, Örzsik B et al. · 2026 · Lipids in health and disease
Background Cardiometabolic factors may influence migraine biology through metabolic, inflammatory, and vascular mechanisms, but studies examining insulin resistance and dyslipidaemia in migraine have yielded inconsistent results, partly…
View details →Negative / Null Result ReportMedicine
Rivas-Nieto AC, Alver SK, Mooney SJ et al. · 2026 · Journal of physical activity & health
Background Physical activity (PA) may be a modifiable factor for chronic kidney disease (CKD) prevention, but evidence specific to Hispanic/Latino populations is limited. Our objective was to examine associations between PA type/volume…
View details →Negative / Null Result ReportMedicine
de Freitas JJA, Nardotto DDMP, Netto LC et al. · 2026 · Infection
Purpose Although advances in intensive care have improved survival of patients with severe leptospirosis, it remains with high mortality. We aimed to identify factors associated with in-hospital mortality among patients with severe…
View details →Negative / Null Result ReportMedicine
Demirci SC, Aşik UB, Menkü BE et al. · 2026 · BMC psychiatry
Background Symptoms of attention-deficit/hyperactivity disorder (ADHD) are commonly observed in individuals with substance use disorders (SUD) and may be associated with increased addiction severity. Time perspective is a potential…
View details →Negative / Null Result ReportMedicine
Gillikin AP, Rabinovich EP, Barajas-Gamboa JS et al. · 2026 · Surgical endoscopy
Background Post-discharge venous thromboembolism (VTE) chemoprophylaxis after metabolic and bariatric surgery is variably implemented in clinical practice, although the optimal pharmacologic agent and dosing regimen remain unclear. This…
View details →Negative / Null Result ReportMedicine
Montalva-Valenzuela F, Guzmán-Muñoz E, Castillo-Paredes A et al. · 2026 · Healthcare (Basel, Switzerland)
Background: The standing long jump (SLJ) is a field-based test of lower-limb muscular fitness in youth and a proposed indicator of health-related physical fitness. However, evidence on its relationship with psychological, sleep, dietary,…
View details →Negative / Null Result ReportMedicine
de Ruyter H, Aitokari L, Iqbal A et al. · 2026 · The Journal of pediatrics
Objective To investigate associations of perinatal and lifestyle factors with alanine aminotransferase (ALT) levels as an early indicator of metabolic dysfunction-associated steatotic liver disease (MASLD). Study design Data from the…
View details →Replication FailureMedicine
Castillo F, Tafur M, Lin C et al. · 2026 · Canadian Association of Radiologists journal = Journal l'Association canadienne des radiologistes
Introduction Nondiagnostic results after thyroid fine-needle aspiration (FNA) are common and may delay diagnosis. Purpose To identify demographic and sonographic predictors of nondiagnostic cytology at repeat thyroid FNA and to report…
View details →Replication FailureMedicine
Rotevatn AØ, Eagan TM, McCann A et al. · 2026 · BMC pulmonary medicine
Background and aim Short-chain fatty acids (SCFAs) are metabolites largely produced by the gut microbiota, except for formate, which is also produced by the host. SCFAs may influence COPD development by modulating the immune system. This…
View details →Negative / Null Result ReportMedicine
Kim BI, Cheng R, Grabov E et al. · 2026 · The Journal of arthroplasty
Background Larger femoral heads have been proposed to reduce dislocation risk following total hip arthroplasty (THA). While the benefit of increasing head size from 28 or 32 mm to ≥ 36 mm is well established, it remains unclear whether…
View details →Negative / Null Result ReportMedicine
Toptas GR, Firatligil FB, Ozdal BB et al. · 2026 · International journal of gynaecology and obstetrics: the official organ of the International Federation of Gynaecology and Obstetrics
Objective To investigate the association between systemic inflammatory indices, including the systemic immune-inflammation index (SII), systemic inflammation response index (SIRI), and aggregate index of systemic inflammation (AISI), and…
View details →Replication FailureMedicine
Soler-Blasco R, Lozano M, González-Safont L et al. · 2026 · Environmental research
Prenatal cadmium (Cd) exposure may impair placental function and disrupt biological processes relevant to foetal neurodevelopment, including oxidative stress and metal homeostasis, but epidemiological evidence linking Cd to childhood…
View details →Negative / Null Result ReportMedicine
Wang Y, Islam RM, Hodge A et al. · 2026 · Fertility and sterility
Objective To determine the associations between the sex steroids and sexual function and difficulties in a national, community-based sample of women aged 40 to 69 years according to menopausal status. Design This was a prespecified…
View details →Negative / Null Result ReportMedicine
Jamieson A, Kwon J, Gao T et al. · 2026 · Gynecologic oncology
Background Race, ethnicity, and geography can impact cancer management, genomics and outcomes. We aimed to determine the ethnic and geographic diversity of endometrial carcinoma (EC) patients in our province and their impact on molecular…
View details →Negative / Null Result ReportMedicine
Chisompola D, Luwaya E, Chalwe JM et al. · 2026 · Scientific reports
Interleukin-17A (IL-17A) is a key cytokine in inflammation and autoimmunity. However, its systemic correlates, particularly in a high HIV burden population, are not fully elucidated. This study aimed to identify the sociodemographic,…
View details →Negative / Null Result ReportMedicine
Murakami K, Shinozaki N, Livingstone MBE et al. · 2026 · The British journal of nutrition
While chrono-nutrition behaviors are inter-related, few studies examined patterns of chrono-nutrition behaviors using a comprehensive set of these behaviors. This study aimed to identify chrono-nutrition behavior patterns and examine their…
View details →Negative / Null Result ReportMedicine
Kleckner AS, Zhou Y, Diaz-Mercado Y et al. · 2026 · Chronobiology international
Circadian rest-activity rhythms, or a person's consistency in their daily activity and rest patterns, can be quantified using various parametric and non-parametric methods. However, these methods are seldom applied to understand symptoms…
View details →Negative / Null Result ReportMedicine
Tsuboi H, Sakakibara H, Minamida-Urata Y et al. · 2026 · Neuro endocrinology letters
Objective Emerging evidence suggests that low-grade systemic inflammation contributes to depressive symptoms; however, population-based longitudinal evidence, particularly from community samples, remains limited. This study examined the…
View details →Negative / Null Result ReportMedicine
Fursule A, Athalye-Jape G, Deepak D et al. · 2026 · Journal of perinatology : official journal of the California Perinatal Association
Objective To assess whether early hypernatremia (HN) and/or hyperglycemia (HG) in the first postnatal week are associated with adverse neurodevelopmental outcomes in extremely preterm (EP; Study design This was a single-center…
View details →Negative / Null Result ReportMedicine
Chegondi M, Jawahar A, Badheka A et al. · 2026 · Perfusion
IntroductionBleeding and clotting phenotypes are common in patients supported with Extracorporeal Membrane Oxygenation (ECMO) and are associated with increased mortality. However, tools to distinguish bleeding from clotting phenotypes…
View details →Negative / Null Result ReportMedicine
Matejak NJ, Ngolobe H, O'Connell CT et al. · 2026 · International journal of infectious diseases : IJID : official publication of the International Society for Infectious Diseases
Objectives Sickle Cell Disease (SCD), characterized by persistently low hemoglobin (Hb) and hematocrit levels, is among the leading causes of under-five mortality in high prevalence countries. Sub-Saharan Africa bears the highest burden of…
View details →Negative / Null Result ReportMedicine
Ada G, Duray M · 2026 · Physiotherapy theory and practice
Background Cervical and trunk proprioceptive deficits resulting from impaired sensorimotor integration post-stroke may contribute to deficiencies in balance reactions and tone regulation. Purpose: To examine relationships between cervical…
View details →Negative / Null Result ReportMedicine
Fredhoff B, Bernstetter A, Fotiou H et al. · 2026 · Complementary therapies in clinical practice
Background and purpose Nutrition likely influences pain, but the role of patient beliefs remains understudied in musculoskeletal conditions. This study examined whether beliefs about the role of nutrition in pain, diet quality, and eating…
View details →Negative / Null Result ReportMedicine
Amodeo AL, Giaquinto V, Reginelli F et al. · 2026 · Psychological reports
The present study examines the associations between other-oriented perfectionism and individual stress within romantic relationships, focusing on the intervening role of social media use as a relational context. Data were collected through…
View details →Failed Experiment ReportMedicine
Portero-Prados FJ, Pabón-Carrasco M, Ponce-Blandón JA · 2026 · Intensive & critical care nursing
Objectives To compare the effectiveness and dermatological safety of chlorhexidine gluconate (CHG)-impregnated dressings versus conventional transparent dressings in preventing central line-associated bloodstream infection (CLABSI) in…
View details →Negative / Null Result ReportMedicine
Jeremias Macedo M, Beirão B, Rodrigues R et al. · 2026 · Blood purification
Introduction Depression is the most prevalent psychiatric disorder among patients with end-stage renal disease receiving hemodialysis (HD), associated with reduced quality of life, poor treatment adherence, higher hospitalization rates,…
View details →Negative / Null Result ReportMedicine
Streubel PN, Sahoo S, Zhang C et al. · 2026 · Journal of shoulder and elbow surgery
Background This study aimed to investigate the associations of general patient and disease-specific factors with baseline patient reported outcome measures (PROMs) in patients undergoing revision rotator cuff repair (RCR). Baseline…
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