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Browse the failure-mode index

12,380 real negative results, null findings, and replication failures in Medicine. Search the index →

WASTE indexes published research — it does not host or republish full papers. Each entry is a metadata record compiled from open scholarly databases; the abstract is shown in full only where the paper is openly licensed, otherwise a short excerpt under fair use. Classifications are automated and approximate.

Negative / Null Result ReportOpen accessMedicine

Does Conflictual Dialogue Improve a Story?

Berks JW, Williams MN · 2026 · Europe's journal of psychology

According to creative writing experts, adding conflict to dialogue improves story quality and audience reaction to that story. This idea draws from the widely held theory that conflict is vital for dramatic stories. Yet despite conflict's…

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Replication FailureOpen accessMedicine

Liposomal Bupivacaine versus Ropivacaine with Dexamethasone in Rectus Sheath Block for Laparoscopic Gastrectomy: A Randomized Controlled Trial.

Yi K, Zhan Y, Wei A et al. · 2026 · Drug design, development and therapy

Background The optimal analgesia regimen for patients undergoing laparoscopic gastrectomy is still unclear. This study evaluated the efficacy of ultrasound-guided rectus sheath block (RSB) with liposomal bupivacaine in providing sustained…

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Negative / Null Result ReportOpen accessMedicine

Preschoolers' Early Sentence Comprehension: Comparing Bilingual and Monolingual Children and the Role of Executive Function and Vocabulary Development.

Rodenhurst N, Messenger K · 2026 · Developmental science

Previous research into children's comprehension of syntactic structures has investigated early awareness of transitive and intransitive structures amongst monolingual children but research into bilingual children's understanding of the…

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Negative / Null Result ReportOpen accessMedicine

Mortality risks associated with short-term exposure to ultrafine particles in London and the West Midlands.

Nenon D, Fuller G, Masselot P et al. · 2026 · Environmental epidemiology (Philadelphia, Pa.)

Background Some research has suggested that ultrafine particles (UFP), with an aerodynamic diameter less than 100 nm, might be the most harmful component of ambient particulate matter air pollution on human health. In the United Kingdom,…

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Negative / Null Result ReportMedicine

Reward learning and attention in risky alcohol use: Absence of Pavlovian influences but altered response bias in high-risk drinkers.

Van der Wielen I, Mrkonja L, Wiers R et al. · 2026 · Behavioural brain research

Reward learning can contribute to addictive behaviors by shaping attention and action selection. While reward-associated stimuli are known to capture attention, it remains unclear whether such learning can also guide behavior without…

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Negative / Null Result ReportMedicine

Vitamin Supplementation and Cardiovascular Disease.

Lipman ET, Frishman WH · 2026 · Cardiology in review

Cardiovascular disease remains the leading cause of morbidity and mortality worldwide. Given the global burden, the potential role of micronutrients-particularly vitamins-in modifying cardiovascular risk has been a topic of intense…

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Negative / Null Result ReportOpen accessMedicine

Healthy Food Voucher Programs: Global Evidence on Structure, Implementation, and Nutrition-Related Outcomes.

Lara-Arevalo J, Corvalan C, Pemjean I et al. · 2025 · Advances in nutrition (Bethesda, Md.)

Healthy food voucher programs (HFVPs) provide lower-income participants with benefits to purchase healthy, nutrient-dense foods and are a promising strategy for improving dietary and nutritional outcomes. HFVPs can complement policies…

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Negative / Null Result ReportMedicine

Do Anti-immigration Rhetoric and Policy Impact Reporting of Intimate Partner Violence To Police Among Latina/e Survivors in the United States? A Comparative Interrupted Time Series Study.

Bevilacqua K, Gemmill A, Jackson D et al. · 2026 · Journal of immigrant and minority health

Latina/e women in the United States (US) experience intimate partner violence (IPV) at similar or lower rates than other women but worse IPV-related health outcomes, perhaps due to barriers to help-seeking. IPV reporting to police is one…

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Negative / Null Result ReportMedicine

Is selenate a diabetogenic form of selenium? Evidence from a natural experiment in Northern Italy.

Vinceti M, Vicentini M, Ottone M et al. · 2026 · Journal of trace elements in medicine and biology : organ of the Society for Minerals and Trace Elements (GMS)

Background Consistent evidence from randomized controlled trials has shown that overexposure to selenium induces type 2 diabetes. However, uncertainties remain about the specific species and doses of selenium that trigger such diabetogenic…

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Negative / Null Result ReportMedicine

Geomagnetic Constraints on Millicharged Dark Matter.

Arza A, Gong Y, Shu J et al. · 2026 · Physical review letters

Millicharged particles are well-motivated dark matter candidates arising in many extensions of the standard model. We show that, despite their tiny coupling e_{m} to photons, millicharged dark matter (mDM) in the Earth's geomagnetic field…

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Negative / Null Result ReportMedicine

Association of oral metoprolol exposure during heart failure hospitalization with death or readmission at 28-days and 6-months using a propensity score overlap-weighted EHR analysis.

Ishaqui AA, Alsaleh EA, Khalil AAA et al. · 2026 · Naunyn-Schmiedeberg's archives of pharmacology

Heart failure (HF) hospitalization is a high-risk transition period with frequent early post-discharge events; we evaluated whether oral metoprolol exposure during the index HF hospitalization is associated with lower all-cause death…

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Negative / Null Result ReportOpen accessMedicine

No Evidence That Women's Sociosexuality or Self-Perceived Mate Value Predict Their Preferences for Men's Face-Shape Masculinity.

Lee P, Li J, Jones BC et al. · 2025 · Evolutionary psychology : an international journal of evolutionary approaches to psychology and behavior

Researchers have suggested that men with more masculine facial characteristics have stronger immune systems but are perceived to be less likely to invest resources in partners and offspring. How women resolve this putative trade-off…

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