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Browse the failure-mode index

12,248 real negative results, null findings, and replication failures in Medicine. Search the index →

WASTE indexes published research — it does not host or republish full papers. Each entry is a metadata record compiled from open scholarly databases; the abstract is shown in full only where the paper is openly licensed, otherwise a short excerpt under fair use. Classifications are automated and approximate.

Negative / Null Result ReportOpen accessMedicine

Does Pain Self-efficacy influence Initial Forward Bending in Adults with Chronic Low Back Pain following Exercise? A Cohort Study.

McManus F, Pranata A, Simpson JA et al. · 2025 · International journal of sports physical therapy

Background/purpose Chronic low back pain affects how individuals bend. Whether pain self-efficacy, a term describing one's confidence in their ability to perform activities despite experiencing pain, affects how much people with chronic…

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Negative / Null Result ReportOpen accessMedicine

Woody seeds and seedlings are unresponsive to herbivore kairomones.

Headrick KC, Pellegrini BA, Santiago EM et al. · 2026 · AoB PLANTS

Herbivory is particularly threatening to young plants that lack the resources needed to survive an attack. Seeds and seedlings should thus benefit greatly from using pre-attack cues to induce defence before damage. Locomotion mucus from…

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Negative / Null Result ReportOpen accessMedicine

Does civilian oversight impact police legitimacy?

Schiff KJ, Schiff DS, Moy BJ et al. · 2025 · PNAS nexus

Does the implementation of external oversight in policing improve public perceptions of police legitimacy? Civilian review boards (CRBs) are frequently promoted as mechanisms to enhance the legitimacy of police agencies by providing…

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Negative / Null Result ReportOpen accessMedicine

Infants Do Not Reliably Track When Bilingual Speakers Switch Languages.

Potter CE, Lew-Williams C · 2025 · Behavioral sciences (Basel, Switzerland)

It is a widely held belief that bilingual infants benefit from hearing each of their languages spoken by different people, as speakers could serve as a cue for separating the two languages. However, it is not yet known whether infants…

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Negative / Null Result ReportOpen accessMedicine

Fascia-Focused Versus Conventional Physiotherapy for Chronic Low Back Pain and Comorbid Depression in Psychosomatic Inpatients.

Overmann L, Steinmeier K, Brandl A et al. · 2026 · Journal of clinical medicine

Background: Chronic low back pain (CLBP) and depression often co-occur. This study compared a fascia-focused physiotherapeutic program with a conventional physiotherapeutic and relaxation-based program in psychosomatic inpatients with CLBP…

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Negative / Null Result ReportOpen accessMedicine

Impact of Stroke History on the Risk of Recurrent Hip Fracture or Major Osteoporotic Fractures among Patients with Incident Hip Fracture: A Nationwide Cohort Study.

Hjelholt TJ, Johnsen SP, Brynningsen PK et al. · 2023 · Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research

Considerable uncertainty prevails regarding risk factors for recurrent fracture among older patients with hip fracture. We aimed to investigate the relationship between prefracture stroke history, baseline mobility, and the risk of…

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Negative / Null Result ReportOpen accessMedicine

Plasma adiponectin levels and risk of heart failure, atrial fibrillation, aortic valve stenosis, and myocardial infarction: large-scale observational and Mendelian randomization evidence.

Nielsen MB, Çolak Y, Benn M et al. · 2024 · Cardiovascular research

Aims Adiponectin may play an important protective role in heart failure and associated cardiovascular diseases. We hypothesized that plasma adiponectin is associated observationally and causally, genetically with risk of heart failure,…

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Negative / Null Result ReportOpen accessMedicine

Can trade and security alliance help reduce interstate war?

Choi SW · 2024 · PloS one

This study explains how the gap between theory and empirical research hinders scientific progress in the area of international political economy. To demonstrate this point, I use Chen's Extended Dependence Theory, which challenges liberal…

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Negative / Null Result ReportOpen accessMedicine

Comparison of oncological outcomes between wedge resection and segmentectomy for T1a/bN0M0 non-small-cell lung cancer: a population-based retrospective cohort study.

Zhang Z, Lian H, Huang L et al. · 2026 · International journal of surgery (London, England)

Background Sublobar resection, including wedge resection (WR) and segmental resection (SR) has been considered for early-stage non-small-cell lung cancer (NSCLC). However, the optimal sublobar approach continues to be a subject of…

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Negative / Null Result ReportOpen accessMedicine

No evidence that averaging voices influences attractiveness.

Ostrega J, Shiramizu V, Lee AJ et al. · 2024 · Scientific reports

Vocal attractiveness influences important social outcomes. While most research on the acoustic parameters that influence vocal attractiveness has focused on the possible roles of sexually dimorphic characteristics of voices, such as…

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Negative / Null Result ReportOpen accessMedicine

Parietal theta burst TMS does not modulate bistable perception.

Schauer G, Grassi PR, Gharabaghi A et al. · 2024 · Neuroscience of consciousness

The role of the parietal cortex in perceptual awareness and in resolving perceptual ambiguity is unsettled. Early influential transcranial magnetic stimulation studies have revealed differences in conscious perception following parietal…

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Negative / Null Result ReportOpen accessMedicine

The relationship between aging out of the special supplemental nutrition program for women, infants, and children assistance and weight status in kindergarten.

Lazic A, Thomsen MR, Brown CC et al. · 2025 · Preventive medicine reports

Objective The Supplemental Nutrition Program for Women, Infants, and Children (WIC) provides access to nutritional resources to low-income children starting at birth through enrollment in kindergarten or turning five years old. The…

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Negative / Null Result ReportOpen accessMedicine

Biomechanical Factors Associated with Intraindividual Differences in Running Economy Across Advanced Footwear Technology Models in Long-Distance Runners.

Fohrmann D, Schaffarczyk M, Menge C et al. · 2026 · Sports medicine - open

Background Advanced footwear technology (AFT) can enhance long-distance running performance by improving running economy (RE). However, the range of the individual improvements is large. Different intra-individual responses in running…

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