Methods Dead-EndMedicine
Ribeiro, Lima · 2026 · ACS omega
Protein interactions are dynamic processes that are influenced by chemical and physical variables. While variable temperatures play an important role in understanding biological processes, their use in protein crystallography has been…
View details →Negative / Null Result ReportMedicine
Raal, Meos, Ainsaar et al. · 2026 · ACS omega
Ascorbic acid (AA) is a key phytochemical marker of rosehip ( Rosa spp.) fruits, but its functional behavior in complex plant matrices remains unclear. Here, we analyzed AA variability in fruits of 14 Rosa spp. (0.26-5.57% dry weight) and…
View details →Negative / Null Result ReportMedicine
Huang, Fu, Yang et al. · 2026 · Neuromodulation : journal of the International Neuromodulation Society
The study aimed to investigate the effects and mechanisms of high-frequency short-pulse gastric electrical stimulation (GES) on gastric emptying and specific myenteric neurons of the gastric antrum in healthy beagle dogs. Four healthy…
View details →Negative / Null Result ReportMedicine
Sabet, Young, Lowder et al. · 2026 · Journal of surgical orthopaedic advances
This study examines the impact of social determinants of health (SDoH) on cardiovascular complications after hand surgery, focusing on income, unemployment, insurance, and education. Using PearlDiver data (2011 - 2022), adult patients with…
View details →Negative / Null Result ReportMedicine
Song, Li, Yao et al. · 2026 · Plants (Basel, Switzerland)
SND (Secondary wall-associated NAC domain) transcription factors are core regulators of secondary cell wall formation in plants. To identify key genes involved in wood formation in Pinus massoniana Lamb. and elucidate the molecular…
View details →Negative / Null Result ReportMedicine
Li, Zhan, Zhang et al. · 2026 · Molecules (Basel, Switzerland)
The present study investigates the effect of 1,8-cineole on improving lipid metabolism disorder by regulating oxidative stress and inflammation via the TLR4/MyD88/NF-κB pathway. 1,8-Cineole is a monoterpene compound widely found in…
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Wang, Ding, Jing et al. · 2026 · IEEE transactions on neural systems and rehabilitation engineering : a publication of the IEEE Engineering in Medicine and Biology Society
Wearable exoskeletons have shown efficacy in gait rehabilitation and locomotor enhancement. Despite much work on the physiological and biomechanical aspects of human-exoskeleton interaction, systematic investigations into how exoskeleton…
View details →Negative / Null Result ReportMedicine
Acipinar, Deveci, Balel · 2026 · Journal of imaging informatics in medicine
This retrospective study aimed to evaluate the effects of diabetes mellitus and periodontitis on alveolar bone density and trabecular bone quality using cone-beam computed tomography (CBCT) and to compare fractal analysis with Hounsfield…
View details →Negative / Null Result ReportMedicine
Brandl, Schmidt, Schleip et al. · 2026 · Journal of bodywork and movement therapies
Recent research has pointed to a crucial role of intra- and extramuscular fascial tissue in force transmission. The paraspinal fascia has been shown to contribute to the maintenance of spinal stability and paraspinal muscle activity. This…
View details →Negative / Null Result ReportMedicine
Tay, Mehta · 2026 · Journal of refractive surgery (Thorofare, N.J. : 1995)
To investigate the safety and efficacy of Nd:YAG capsulotomy to treat posterior capsule opacification in eyes implanted with the IC-8 Apthera intraocular lens (IOL) (Bausch Surgical). This was a retrospective, non-randomized,…
View details →Replication FailureMedicine
Gao, Guan, Lv et al. · 2026 · Frontiers in plant science
To address the issues of imbalanced fertilizer application ratios and low nutrient use efficiency during the seedling stage of daylily, this study used 'Datong Huanghua' as the plant material. A pot experiment was conducted based on local…
View details →Negative / Null Result ReportMedicine
van Zadelhoff, van der Heijden, Bierma-Zeinstra et al. · 2025 · Osteoarthritis imaging
This paper summarizes the current evidence on genicular artery embolization (GAE) for the treatment of knee osteoarthritis (OA). The goal of this minimally invasive treatment is to reduce synovitis by embolizing peri‑genicular…
View details →Negative / Null Result ReportMedicine
Li, Shi, Chen et al. · 2026 · Frontiers in medicine
Pulmonary alveolar proteinosis (PAP) is a rare respiratory disorder characterized by the excessive accumulation of surfactant material on alveolar surfaces and the dysfunction of alveolar macrophages. Indium-tin-oxide (ITO), a substance…
View details →Negative / Null Result ReportMedicine
Alabrash, Khalil · 2026 · Cureus
This study aimed to assess transverse skeletal differences between Class I and Class II malocclusion using the J-J/Ag-Ag ratio derived from frontal cephalometric analysis. A retrospective cross-sectional study was conducted on 28 patients…
View details →Negative / Null Result ReportMedicine
Chiarelli, Lynd, Bergamo et al. · 2026 · Metabolic engineering communications
Glycolysis is central to Clostridium thermocellum metabolism; however, strains engineered for high ethanol titer exhibit a decrease in the conversion of cellobiose to ethanol (i.e., cellobiose-to-ethanol yield), suggesting the presence of…
View details →Negative / Null Result ReportMedicine
Guan, Li, Wu et al. · 2026 · Zhongguo shi yan xue ye xue za zhi
To evaluate the effects of Bone Morphogenetic Protein 4( BMP4 ) overexpression mediated by an adenoviral vector on immunophenotype features, migration ability, colony-forming ability, and early osteogenic differentiation potential of human…
View details →Negative / Null Result ReportMedicine
Saied, Yousuf, Rahman et al. · 2026 · Journal of advanced veterinary and animal research
Objectives: This study aimed to determine the optimal dose of quercetin (plant origin) on growth performance, nutrient digestibility, meat composition, shank mineralization, and production costs in broilers. Materials and Methods: A total…
View details →Negative / Null Result ReportMedicine
Afari, Hang, Su et al. · 2026 · Food microbiology
This study provides the first systematic, commercial-scale evaluation of Listeria innocua survival on multiple pear cultivars under long-term storage. We investigated its fate on three pear varieties (d'Anjou, Bartlett, and Bosc) across…
View details →Negative / Null Result ReportMedicine
García-Pintos, Menchaca · 2026 · Veterinary and animal science
This study aimed to assess the impact of foot-and-mouth disease (FMD) vaccination on milk production in dairy cows. In Experiment 1, 593 lactating Holstein cows (37.2 ± 0.3 kg/day), housed in a free-stall system, were randomly…
View details →Negative / Null Result ReportMedicine
Clemen, Humbsch, Berwanger et al. · 2026 · Physiological reports
The cross-sectional Master Athletic Laboratory Study of Intramuscular Connective Tissue (MALICoT, DRKS00015764) examined effects of athletic exercise and age on endomysium content in human soleus muscle. Forty-three clinically healthy male…
View details →Negative / Null Result ReportMedicine
Ramezankhani, Hadaegh, Esmaeili · 2026 · BMC cardiovascular disorders
Studies evaluating the longitudinal relationship between plasma free fatty acids (FFAs) and subclinical atherosclerosis remain limited. We investigated the prospective association between serum FFA levels and the progression of coronary…
View details →Negative / Null Result ReportMedicine
Xie, Chen, Xie et al. · 2026 · Scientific reports
The triglyceride-glucose (TyG) index is a simple surrogate marker for insulin resistance (IR), but its longitudinal stability and clinical predictive value in patients with cancer remain poorly understood. To evaluate whether cancer and…
View details →Negative / Null Result ReportMedicine
Ferreira, Marques, Neves et al. · 2026 · JACC. Heart failure
Hypertension and heart failure with preserved ejection fraction (HFpEF) often coexist, and sodium retention is a common feature of both conditions. Renin levels are suppressed in the setting of sodium overload and may modulate the blood…
View details →Negative / Null Result ReportMedicine
Seņkovs, Nikolajeva, Rubene et al. · 2026 · Pathogens (Basel, Switzerland)
The increasing demand for sustainable plant protection products has intensified interest in microbial biocontrol agents (BCAs). This study aimed to evaluate the antifungal activity of selected Streptomyces , Bacillus , and Trichoderma…
View details →Negative / Null Result ReportMedicine
Schlemmer, Hammer, Fandler-Höfler et al. · 2026 · Nutrients
Background : The plant Griffonia simplicifolia is marketed as a dietary supplement; it is said to have antidepressant and sleep-promoting properties. Its main ingredient, 5-hydroxytryptophan (5-HTP), is the immediate precursor of serotonin…
View details →Negative / Null Result ReportMedicine
Rovira-Lastra, ElOtmani-Sabiri, Ustrell-Barral et al. · 2026 · Diagnostics (Basel, Switzerland)
Background/Objectives : This clinical study assessed the validity of articulating paper for detecting occlusal contacts points, including examining the effects of clinical technique, paper thickness, and the arch. Methods : This…
View details →Negative / Null Result ReportMedicine
Ahmed, Nath, Jahan et al. · 2026 · International journal of environmental research and public health
Conventional anthropometric measures used to predict dyslipidemia, such as body mass index and waist circumference, vary over time and may not fully capture early-life influences on metabolic risk. Fixed skeletal proportions, including…
View details →Negative / Null Result ReportMedicine
Reysner, Ciftci, Alver et al. · 2026 · Journal of clinical medicine
Background: The pericapsular nerve group block provides motor-sparing analgesia after total hip arthroplasty, but the optimal injectate volume and the role of dexamethasone remain unclear. Methods: In this prospective, randomized,…
View details →Negative / Null Result ReportMedicine
Marici, Marina, Cormoș · 2026 · Behavioral sciences (Basel, Switzerland)
This study aimed to develop and validate a brief measure of hope for romantic relationships (HRR), conceptualized as a future-oriented evaluation of relational continuity and quality. The sample consisted of 525 participants. Exploratory…
View details →Negative / Null Result ReportMedicine
Kandemir, Yüksel, Çam Yanık et al. · 2026 · Pain management nursing : official journal of the American Society of Pain Management Nurses
Patients undergoing open-heart surgery often experience procedural pain and anxiety during chest tube removal (CTR), which can lead to serious complications, along with potential changes in hemodynamic parameters such as blood pressure,…
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