12,248 real negative results, null findings, and replication failures in Medicine. Search the index →
WASTE indexes published research — it does not host or republish full papers. Each entry is a metadata record compiled from open scholarly databases; the abstract is shown in full only where the paper is openly licensed, otherwise a short excerpt under fair use. Classifications are automated and approximate.
Wang Y, Kong X, Wei H et al. · 2025 · Haemophilia : the official journal of the World Federation of Hemophilia
Introduction The Bethesda assay (BA) and the Nijmegen-Bethesda assay (NBA) are commonly used to measure inhibitors in patients with haemophilia A (HA). The laboratory results of inhibitor assays have been demonstrated to be highly…
View details →Hall AD, Whitehurst DA, Mortensen JE et al. · 2025 · Journal of infection and chemotherapy : official journal of the Japan Society of Chemotherapy
Malaria remains a significant public health concern in sub-Saharan Africa, particularly in Ethiopia where Plasmodium falciparum and Plasmodium vivax are co-endemic. Most cases in the United States are acquired abroad and imported.…
View details →Atencia S, Mateu N, Rodríguez-Cobos A et al. · 2025 · Veterinary research communications
Bordetella bronchiseptica (Bb) is a frequent pathogen in dogs and a component of the Canine Infectious Respiratory Disease Complex (CIRDC). However, it can also be detected in the lower respiratory tract of healthy animals, complicating…
View details →Kaya G, Yüksel H, Taneli F et al. · 2026 · Clinical and translational science
In cat sensitized children, decision to eliminate exposure to cats depends on the clinical outcome. In this study, we aimed to examine the relationship between molecular cat allergen sensitization and exhaled breath condensate (EBC) IL-4,…
View details →Khin STMM, Jafar SM, Ju M et al. · 2025 · Journal of virological methods
Feline morbillivirus (FeMV) is a globally emerging virus that has been linked to chronic kidney disease (CKD) in infected cats. Immunological assays, such as enzyme-linked immunosorbent assay (ELISA), are important for studying the virus…
View details →Lagström RMB, Bräuner KB, Frandsen MN et al. · 2026 · Endoscopy international open
Background and study aims Because most colorectal polyps are diminutive and carry minimal cancer risk, artificial intelligence (AI) might enable diagnostic strategies such as leave-in-situ and resect-and-discard, provided it meets…
View details →Javaugue V, Pascal V, Nasr SH et al. · 2025 · Kidney international
Introduction Proliferative glomerulonephritis with monoclonal immunoglobulin deposits (PGNMID) is classified within the spectrum of monoclonal gammopathy of renal significance (MGRS). However, PGNMID features an unexpected low rate of…
View details →Calabrese V, Metro D, Alibrandi A et al. · 2025 · Nefrologia
The Classification and Regression Tree (CART) is a supervised learning approach useful used to segment the space of and the predictors/features space into smaller homogeneous regions that are, represented in a decision tree. It computes…
View details →Costa TH, Bonet-Bub C, Kutner JM · 2024 · Hematology, transfusion and cell therapy
Background and objectives The identification of platelet antibodies is essential for diagnosing and managing conditions such as fetal and neonatal alloimmune thrombocytopenic purpura, post-transfusion purpura, and immune platelet…
View details →Epchtien RE, Temkin E, Masarwa S et al. · 2025 · European journal of clinical microbiology & infectious diseases : official publication of the European Society of Clinical Microbiology
We evaluated whether skin sampling with E-swabs is an effective alternative to pre-moistened sponges for detecting carbapenem-resistant Acinetobacter baumannii (CRAB) carriage. Skin samples were collected by sponges with enrichment and…
View details →Cullinane A, Nelly M, Dayot L et al. · 2025 · Viruses
This study describes a comparison of the detection of rotavirus in clinical samples from foals using two commercially available rapid antigen detection (RAD) kits, with the detection of rotavirus nucleic acid via a laboratory-based,…
View details →Chen Z, Trivedi AN, Rahman M et al. · 2026 · JAMA internal medicine
Importance On May 12, 2023, the Medicare program reinstated the long-standing 3-day hospitalization rule for skilled nursing facility (SNF) care after it had been waived for more than 2 years during the COVID-19 pandemic. This abrupt…
View details →Hayden JE, Deane CS · 2026 · Current opinion in clinical nutrition and metabolic care
Purpose of review To critically review recent findings related to the effects of omega-3 fatty acid supplementation on skeletal muscle, with a particular focus on skeletal muscle protein turnover and mitochondrial function. Recent findings…
View details →Chei CL, Nakamura S, Watanabe K et al. · 2025 · International journal of cancer
Chest x-ray (CXR) is widely used for lung cancer screening in Japan. We evaluated the sensitivity and specificity of CXR in detecting early lung cancer and its histological types. We cross-referenced lung cancer municipality screening data…
View details →Shi Q, Bao J, Li J et al. · 2025 · Respirology case reports
Occult bronchial foreign bodies are extremely rare in adults. Affected patients typically lack a clear history of aspiration, exhibit no characteristic clinical signs and present with unremarkable chest imaging, often leading to…
View details →Liang S, Wang J, Fu W et al. · 2026 · Diagnostics (Basel, Switzerland)
Objective: The integration of artificial intelligence (AI) into computer-aided detection (CAD) is a major innovation in lung cancer diagnosis. However, its reliability in detecting the earliest radiographic sign-faint ground-glass…
View details →Asanoma K, Yahata H, Kodama K et al. · 2025 · Asian journal of endoscopic surgery
Introduction This study examined factors that affected sentinel lymph node (SLN) identification of patients with endometrial cancer having a preoperative estimation of low recurrent risk. Methods This study included 97 patients with…
View details →Zhang Z, He S, Li X et al. · 2024 · Zhonghua yi xue yi chuan xue za zhi = Zhonghua yixue yichuanxue zazhi = Chinese journal of medical genetics
Objective To assess the value of optical genome mapping (OGM) for the detection of chromosomal structural abnormalities including ring chromosomes, balanced translocations, and insertional translocations. Methods Clinical data of four…
View details →Esmeraldo MA, Chambers S, Kravutske Y et al. · 2026 · Brain informatics
Purpose MELD Graph is a state-of-the-art artificial intelligence (AI) model for automated detection of focal cortical dysplasia (FCD), but its performance remains limited, highlighting the need to investigate which aspects of the pipeline…
View details →Andová N, Repiská V, Priščáková P et al. · 2026 · Case reports in women's health
False-negative results in non-invasive prenatal testing are rare but clinically significant, particularly in the presence of biological factors such as feto-placental mosaicism. This report describes a pregnancy affected by fetal trisomy…
View details →Okuno-Ozeki N, Kohama Y, Taguchi H et al. · 2025 · Scientific reports
Reducing salt intake is crucial for managing hypertension. While efforts to reduce salt intake are based on the assumption that people have a preference for salt, it is also important to acknowledge that there is an aversion to high levels…
View details →Eremichev R, Nikolaeva N, Khandokhin M et al. · 2025 · Biology
Recent discovery of menstruation in the Egyptian spiny mouse ( Acomys cahirinus) highlighted this species as a feasible model for the study of menstrual cycle physiology. However, reports on active menstrual bleeding in this animal were…
View details →Yang R, Wang Y, Fu Q et al. · 2026 · BMJ open
Objectives To establish optimal pre-pregnancy body mass index (BMI)-specific gestational weight gain (GWG) ranges for twin pregnancies and compare their association with maternal and neonatal adverse outcomes against Institute of Medicine…
View details →Saito A, Terai H, Kim TJ et al. · 2024 · Cancer medicine
Background Companion diagnostic tests play a crucial role in guiding treatment decisions for patients with non-small cell lung cancer (NSCLC). The Oncomine Dx Target Test (ODxTT) Multi-CDx System has emerged as a prominent companion…
View details →Awaly M, Norton M, Ahmed D et al. · 2025 · Cureus
Midline laparotomy remains essential in gynecological oncology, and rectus sheath catheters (RSCs) are commonly used for postoperative analgesia. We report the case of a 46-year-old woman who underwent midline laparotomy for a suspected…
View details →Salimkhanov R, Utkina M, Bagirova H et al. · 2025 · Frontiers in endocrinology
Multiple endocrine neoplasia type 1 (MEN-1; OMIM 131100) is a rare, autosomal dominant syndrome caused by heterozygous inactivating mutations in the MEN1 tumor suppressor gene (11q13; OMIM 613733). MEN-1 is characterized by polyglandular…
View details →Miquel-Rodríguez R, González-Toledo B, Pérez-Gómez MV et al. · 2024 · International journal of molecular sciences
Autosomal polycystic kidney disease (ADPKD) is the most common genetic form of kidney failure, reflecting unmet needs in management. Prescription of the only approved treatment (tolvaptan) is limited to persons with rapidly progressing…
View details →Vinyard DJ, Govindjee G · 2024 · Photosynthesis research
Photosystem II (PSII) uses light energy to oxidize water and to reduce plastoquinone in the photosynthetic electron transport chain. O 2 is produced as a byproduct. While most members of the PSII research community agree that O 2…
View details →Halalsheh H, Odeh N, Kiswani A et al. · 2026 · Cancers
Background Accurate staging is vital for optimizing outcomes in pediatric rhabdomyosarcoma (RMS). While [ 18 F]-FDG PET/CT is increasingly utilized, its specific impact on clinical management and its prognostic value compared to…
View details →De Ryst JE, Bergström S, Mravinacova S et al. · 2026 · Fluids and barriers of the CNS
Background Aquaporin-4 (AQP4) is crucial for brain fluid regulation and glymphatic system function. Idiopathic normal pressure hydrocephalus (INPH) is characterized by impaired CSF flow and is treated with shunt surgery. This study…
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