e-ISSN: Pending
Negative / Null Result ReportMedicine

Neuroprotective mechanisms of Thai traditional brain tonic Phy-Blica-O against LPS-induced neuroinflammation: Inhibition of NF-κB in microglia and mice.

Kaewmanee; Ganesan; Choochana; Na-Phatthalung; Kehinde; Chusri · 2026 · PloS one

WASTE classifies this as Negative / Null Result Report · AI classification, approximate

The study found no significant effect — useful as a negative control or null benchmark for your own design.

Abstract (excerpt)

Phy-Blica-O (PBO) is a traditional Thai polyherbal formulation historically regarded as a brain tonic and memory enhancer. Despite its long-standing ethnomedicinal use, its neuroprotective mechanisms have not been scientifically validated.…

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Metadata source: PubMed · DOI 10.1371/journal.pone.0352429