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WASTE Journal

Browse the failure-mode index

12,246 real negative results, null findings, and replication failures in Medicine. Search the index →

WASTE indexes published research — it does not host or republish full papers. Each entry is a metadata record compiled from open scholarly databases; the abstract is shown in full only where the paper is openly licensed, otherwise a short excerpt under fair use. Classifications are automated and approximate.

Negative / Null Result ReportMedicine

Real-world impact of artificial intelligence on adenoma detection: A cross-sectional study at a single center in Lima, Peru.

Guillen B, Zambrano-Huailla R, Chirinos JA · 2026 · Revista de gastroenterologia de Mexico (English)

Introduction The use of artificial intelligence (AI) in endoscopic studies has grown in recent years. The present study evaluates the performance of AI in detecting polyps and adenomas in daily clinical practice. Materials and methods A…

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Negative / Null Result ReportMedicine

A Follow-Up Study of the Supraaortic and Intracranial Vessels, Cerebrovascular Reactivity, Brain Vascular Lesions and Atrophy in Patients with Rheumatoid Arthritis.

Sas A, Jónyer D, Valikovics A et al. · 2026 · Journal of clinical medicine

Background/Objectives: Rheumatoid arthritis (RA) has been associated with accelerated atherosclerosis and cerebrovascular alterations. Our 2017 study compared 60 RA patients to healthy controls, assessing vascular, neurological, and…

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Negative / Null Result ReportMedicine

Risk of major bleeding events associated with concomitant use of selective serotonin reuptake inhibitors and anti-thrombotic drugs: a nationwide case-case-time-control study.

Kim S, Kim JH, Shin JY et al. · 2026 · Age and ageing

Background Depression is common in older adults, who are also at elevated risk of bleeding due to age-related physiological changes and comorbidities. Concerns have been raised regarding potential bleeding risk from concomitant use of…

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Negative / Null Result ReportOpen accessMedicine

Postoperative radiotherapy improves overall survival and was not associated with a statistically significant increase in cardiac-specific mortality in thymoma patients: a propensity score-matched analysis of the SEER database.

Wang R, Dai P, Deng X et al. · 2026 · Journal of thoracic disease

Background Thymoma is an uncommon cancer of the thymus and postoperative radiotherapy (PORT) is often considered for selected patients with high-risk or locally advanced thymoma after resection. The effect of PORT on overall survival (OS)…

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Negative / Null Result ReportOpen accessMedicine

Evaluation of Differences in Imaging Findings on Stress-MRI in Throwing Athletes With and Without a History of Ulnar Collateral Ligament Reconstruction.

Patel M, Schwartz K, Schenk M et al. · 2026 · Orthopaedic journal of sports medicine

Background Ulnar collateral ligament (UCL) reconstruction (UCLR) of the elbow is common in throwing athletes and reliably allows return to play. The literature supports stress imaging of the elbow to evaluate the integrity of the UCL. The…

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Negative / Null Result ReportOpen accessMedicine

Impact of a Routine Third Trimester Ultrasound Policy on Obstetric, Neonatal and Service Delivery Outcomes in an Australian Tertiary Centre.

Kumar P, Gordon A, Fisher E et al. · 2026 · The Australian & New Zealand journal of obstetrics & gynaecology

Background Routine third trimester ultrasound scans have been introduced in several maternity centres to increase detection of fetal growth disorders and improve perinatal outcomes. Aims To assess changes in obstetric and neonatal outcomes…

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Negative / Null Result ReportOpen accessMedicine

Photobiomodulation at 830 nm with 5 J/cm<sup>2</sup> does not promote PI3K/AKT/mTOR signalling pathway activation in hyperglycemic wounded cells.

Kasowanjete P, Dhilip Kumar SS, Houreld N · 2026 · Lasers in medical science

The phosphatidylinositol 3-kinase (PI3K), protein kinase B (AKT), mammalian target of rapamycin (mTOR) (PI3K/AKT/mTOR) pathway regulates cell survival, proliferation, and the synthesis of protein. Photobiomodulation (PBM) stimulates…

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Negative / Null Result ReportOpen accessMedicine

The effect of sodium bicarbonate mini-tablets in a carbohydrate hydrogel on prolonged high-intensity cycling performance and metabolism in acute normobaric hypoxia.

Shannon ES, Sparks SA, McNaughton LR et al. · 2026 · European journal of applied physiology

PURPOSE: Hydrogen cation (H+) accumulation is exacerbated in hypoxia. Sodium bicarbonate (NaHCO3) ingestion can reduce fatigue associated with high-intensity exercise performance by counteracting H+ ion accumulation. The present study…

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Negative / Null Result ReportMedicine

Multidimensional Predictors of Ranking-Based Competitive Success in National-Level Junior Tennis Players: Evidence for the Dominant Role of Physical Performance.

Géczi R, Géczi G, Tóth L · 2026 · Sports (Basel, Switzerland)

The aim of this study was to examine the relative contribution of physical performance, executive functions, and competitive anxiety to competitive success in junior tennis players. A total of 39 national-level junior athletes (20 males,…

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Negative / Null Result ReportMedicine

Assessment of the relationship between sustainable and healthy eating behaviours, acceptance of alternative protein sources (plant-based products, mushroom protein, algae, artificial meat, edible insects) and food neophobia in young adults.

Karahan Yılmaz S, Güldüren S · 2026 · Nutricion hospitalaria

Introduction Introduction: a growing world population, constraints on natural resources and changing nutritional preferences all point to the need to find an alternative to traditional animal protein sources however food neophobia can come…

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Negative / Null Result ReportMedicine

Conversion Rates From Initial Consultation to Bariatric Surgery: A Single-Center Community Practice Experience.

McDonough W, Gevorkian J, Wong D et al. · 2026 · Surgical laparoscopy, endoscopy & percutaneous techniques

Background As part of the accreditation process for bariatric surgery, patients must go through a preoperative pathway. There will inevitably be patients who are seen in the clinic but never undergo surgery. This rate of attrition is…

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Negative / Null Result ReportOpen accessMedicine

Pemafibrate therapy increases serum zinc levels in patients with metabolic dysfunction-associated steatohepatitis: a prospective study.

Wakui N, Ogino Y, Nagumo H et al. · 2026 · BMC gastroenterology

Background Zinc deficiency is common in chronic liver disease and is closely associated with the progression of hepatic fibrosis and metabolic dysfunction. Although pemafibrate, a selective peroxisome proliferator-activated receptor alpha…

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Negative / Null Result ReportOpen accessMedicine

The effect of a community intervention based on protection motivation theory on brucellosis preventive behaviors in rural residents.

Ebrahimi S, Tehrani H, Ghavami V et al. · 2025 · Journal of education and health promotion

Background Brucellosis is a major bacterial infectious disease common to human beings and animals. It is considered a prevalent infection in developing countries. The present research was carried out to explore the effect of an educational…

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