e-ISSN: Pending
WASTE Journal

Browse the failure-mode index

12,246 real negative results, null findings, and replication failures in Medicine. Search the index →

WASTE indexes published research — it does not host or republish full papers. Each entry is a metadata record compiled from open scholarly databases; the abstract is shown in full only where the paper is openly licensed, otherwise a short excerpt under fair use. Classifications are automated and approximate.

Negative / Null Result ReportOpen accessMedicine

Do the Pre-Existing Class III and Class V Composite Restorations Affect the Sealing Ability and Integrity of 3D-Printed Laminate Veneer Margins? An In Vitro Study.

Qaraghuli AM, Cagidiaco EF, Ferrari M · 2026 · Journal of functional biomaterials

Background: The application of veneer restorations over previously composite-restored anterior teeth presents significant clinical challenges, particularly in achieving optimal marginal sealing. Aim: This in vitro study aimed to evaluate…

View details →
Negative / Null Result ReportOpen accessMedicine

Current status of 5-aminosalicylic acid in Crohn's disease treatment: a nationwide survey and analysis of perspectives and practice patterns among inflammatory bowel disease physicians.

Li Y, Chen C, Wang C · 2026 · Frontiers in gastroenterology (Lausanne, Switzerland)

Objective To investigate the perspectives and clinical practice patterns of inflammatory bowel disease (IBD) physicians regarding the use of 5-aminosalicylic acid (5-ASA) in Crohn's disease (CD). Methods A 21-item questionnaire was…

View details →
Negative / Null Result ReportMedicine

Acute effects of the FIFA 11 + kids warm-up program compared with a judo-specific warm-up on explosive and functional performance in youth judo athletes: a randomized crossover study.

Mor H, Şar H, Arslan T et al. · 2026 · BMC sports science, medicine & rehabilitation

Background The FIFA 11 + Kids (FIFA 11+) warm-up program is effective for injury prevention and to enhance sports performance, including vertical jump (VJ), sprint, balance, and agility. However, no previous study has examined the acute…

View details →
Negative / Null Result ReportOpen accessMedicine

Non-tobacco nicotine dependence is associated with increased complications following clavicle open reduction internal fixation.

Adio AA, Goyal RK, Skiena A et al. · 2026 · Archives of orthopaedic and trauma surgery

Background Tobacco dependence is well established to impair bone healing and increase postoperative complications. However, the independent effects of nicotine, separate from combustion-related factors, remain unclear. This study aimed to…

View details →
Abandoned HypothesisMedicine

[Clinical and genetic characteristics of infantile-onset Pompe disease​ and long-term efficacy of enzyme replacement therapy].

Sun YM, Wang YJ, Wang HF et al. · 2026 · Zhonghua er ke za zhi = Chinese journal of pediatrics

Objective: To analyze the clinical and genetic characteristics of infantile-onset Pompe disease (IOPD) and evaluate the long-term efficacy of enzyme replacement therapy (ERT). Methods: A retrospective cohort study was conducted on 24 IOPD…

View details →
Negative / Null Result ReportOpen accessMedicine

Effects of Defatted Black Soldier Fly (<i>Hermetia illucens</i>) Meal on the Performance, Digestibility and Blood Parameters of Weaned Piglets.

Parreiras M, Pinheiro V, Moreira O et al. · 2026 · Animals : an open access journal from MDPI

This study investigated the effects of different inclusion levels of defatted black soldier fly ( Hermetia illucens : BSF) larval meal on growth performance, haematological and biochemical blood parameters, and nutrient digestibility in…

View details →
Negative / Null Result ReportMedicine

Exploratory Study of Radiation Exposure between Image Intensifier-Equipped C-Arm and a Flat Panel Detector During Volar Plate Fixation of the Distal Radius.

Honda Y, Kaida E, Miyazaki Y et al. · 2026 · The journal of hand surgery Asian-Pacific volume

Background: To compare the amount of radiation exposure received by the surgeon during volar locking plate fixation for distal radius fractures using an image intensifier (II) and a flat panel detector (FPD). Methods: We included 40…

View details →
Negative / Null Result ReportOpen accessMedicine

Evaluation of the effects of different irrigation activation techniques on the surface roughness of dentin and blood clot in regenerative endodontic models.

Bulak Yeliz S, Uğur Aydın Z · 2026 · Lasers in medical science

Regenerative endodontic treatment (RET) is a biologically based approach aiming to restore the pulp-dentin complex in immature permanent teeth with necrotic pulps. In this procedure, a blood clot is induced within the canal to serve as a…

View details →
Negative / Null Result ReportOpen accessMedicine

Clinical Status and Salivary aMMP-8 Evaluation of 0.12% Chlorhexidine Versus MicroRepair<sup>®</sup> ABX Mouthwash in the Non-Surgical Management of Plaque-Induced Gingivitis: A Randomized Controlled Trial.

Scribante A, Pascadopoli M, Pellegrini M et al. · 2026 · Dentistry journal

Objectives : To compare the adjunctive efficacy of a MicroRepair ® mouthwash containing an antibacterial complex (ABX), composed of cetylpyridinium chloride, magnolol, and honokiol, with 0.12% chlorhexidine (CHX) in the management of…

View details →
Negative / Null Result ReportOpen accessMedicine

Safety of flexible bronchoscopy in elderly patients.

Spiegel S, Hübner RH, Schürmann D et al. · 2026 · BMC pulmonary medicine

Background Flexible bronchoscopy is an indispensable tool in respiratory medicine. In the context of an aging society and increasing life expectancy, the number of elderly, often multimorbid patients is growing. This raises important…

View details →
Negative / Null Result ReportOpen accessMedicine

Effect of conventional warm-up versus stretching warm-up on physical performance in children soccer players: a randomized crossover trial.

Hernandez-Martínez J, Cid-Calfucura I, Perez-Carcamo J et al. · 2026 · Frontiers in physiology

Introduction To evaluate the effects of the conventional warm-up (CC) compared to warm-ups that included static (SSC), dynamic (DSC), or ballistic (BSC) stretching on jump performance (CMJ, SJ, DJ), curve sprint speed, agility (ICODT), and…

View details →
Negative / Null Result ReportOpen accessMedicine

Assessment of pain and post-injection induration in children: A comparative study of cold application, manual pressure, and shot blocker techniques.

Sasireka V, Bhuvaneswari G, Babu S · 2026 · Journal of education and health promotion

Background Intramuscular (IM) injections are widely used in pediatric care but often cause pain and distress. Effective management is essential to improve children's healthcare experiences. Non-pharmacological methods, including Cold…

View details →
Negative / Null Result ReportOpen accessMedicine

Critical care ultrasound evaluation of snuffbox artery vascular tension: a prospective observational study between healthy volunteers and intensive care unit patients.

Qin Y, Zhu Y, Dai X et al. · 2026 · Frontiers in medicine

Background Systemic vascular resistance is conventionally assessed using invasive methods; the snuffbox artery resistance index (RI) is a superior non-invasive predictor of lactate clearance in septic shock patients to the perfusion index.…

View details →
Negative / Null Result ReportOpen accessMedicine

Deficit irrigation and grafting effects on soil attributes, vegetative growth, yield components, and quality of 'Crimson Seedless' grapevines under a semiarid region.

Salama AM, Al-Obeed RS, Helmy A et al. · 2026 · Frontiers in plant science

This study evaluated the combined effects of grafting and deficit irrigation (DI) on soil attributes, vegetative growth, yield components, fruit quality, and water productivity of 'Crimson Seedless' grapevines under semiarid conditions. It…

View details →
Negative / Null Result ReportMedicine

Comparison of the efficacy of posterior lumbar interbody fusion and transforaminal lumbar interbody fusion in the treatment of double-level lumbar spondylolisthesis combined with spinal stenosis: a retrospective comparative study.

Ma Z, Luan H, Abulimiti K et al. · 2026 · BMC surgery

Objective To compare the clinical and radiographic outcomes of posterior lumbar interbody fusion (PLIF) and transforaminal lumbar interbody fusion (TLIF) in the treatment of double-level lumbar spondylolisthesis combined with spinal…

View details →
Negative / Null Result ReportMedicine

The Effect of Preoperative Tranexamic Acid on Blood Transfusions in Geriatric Hip Fracture Surgery: A Randomized Controlled Trial.

Sullivan M, Perea LL, Bradburn E et al. · 2026 · Journal of orthopaedic trauma

Objectives To evaluate whether preoperative intravenous tranexamic acid (TXA) reduces postoperative blood transfusion rates in geriatric patients undergoing operative treatment for hip fracture. Methods Design Prospective, double-blinded,…

View details →