12,379 real negative results, null findings, and replication failures in Medicine. Search the index →
WASTE indexes published research — it does not host or republish full papers. Each entry is a metadata record compiled from open scholarly databases; the abstract is shown in full only where the paper is openly licensed, otherwise a short excerpt under fair use. Classifications are automated and approximate.
Ashmore S, Russo D, Hornbach A et al. · 2026 · Urogynecology (Philadelphia, Pa.)
Importance Surgeons traditionally place the synthetic midurethral sling (MUS) after completing the apical suspension procedure during surgical procedures for pelvic organ prolapse (POP) and stress urinary incontinence (SUI). We hypothesize…
View details →Çetin OG, Gülgöz S · 2026 · Memory (Hove, England)
The role of agency in collective memory is largely unexplored, and evidence that schema-congruent collective events are more readily integrated than incongruent ones remains largely correlational. Studying these factors experimentally is…
View details →Kawasaki Y, Suzuki Y, Miyazaki K et al. · 2026 · Fukushima journal of medical science
Aim To clarify the change in characteristics and body mass index standard deviation (BMI-SD) after guanfacine extended-release (GXR) administration for attention-deficit/hyperactivity disorder (ADHD) children, we undertook a clinical…
View details →Lu C, Gil D, Lefeuvre M et al. · 2026 · The Journal of experimental biology
Climate variability and unpredictability present animals with challenging physiological and behavioural demands. However, empirical studies on endotherms involving manipulated environmental variability remain limited. This study…
View details →Niemann AS, Ramon R, Mayor J et al. · 2026 · Life (Basel, Switzerland)
(1) Background: The reconstruction of periacetabular defects after tumor resection remains one of the most challenging procedures in orthopaedic oncology. The modular LUMiC ® system was designed to improve fixation stability and reduce…
View details →Koumpias AM, Kirch M, Steppe E et al. · 2026 · Journal of women's health (2002)
Background Obtaining a National Institutes of Health (NIH) career development (K) award is a pivotal milestone for early-career faculty, contributing not only to individual career progression but also to the diversity of the biomedical…
View details →Comlekci M, Yıldız AE, Demirel A · 2026 · BMC sports science, medicine & rehabilitation
Background Ankle sprains are among the most common injuries in athletes, accounting for approximately 80% of all athletic injuries. Recurrent ankle sprains often progress to chronic ankle instability (CAI), which can impair athletic…
View details →Abdelnaby EA, Alhaider AK, Emam IA · 2026 · Veterinary sciences
This current study aimed to determine the impact of Mitoquinone (MitoQ) on the quality of frozen-thawed donkey semen. Ejaculates were collected from six male donkeys ( Equus asinus ), and ejaculates were polled and aliquoted into 12…
View details →Trakarnvanich T, Nochaiwong S, Ruengorn C et al. · 2026 · Scientific reports
To date, little is known regarding the treatment effects of different timed-dosing antihypertensive medications among hypertensive patients with albuminuria. We aimed to investigate whether morning or evening dosing of antihypertensive…
View details →Randunu RS, Huber LA, Van Vliet BN et al. · 2026 · The Journal of nutrition
Background Developmental programming is a key determinant of adult hypertension. Total parenteral nutrition (TPN) can exert nutritional stress during development and cause irreversible programming of metabolism via epigenetic…
View details →Abe I, Kubo K, Fujita Y et al. · 2026 · Drug discoveries & therapeutics
The metabolic and endocrinological effects in patients with adult growth hormone deficiency (AGHD) who switched from daily growth hormone (GH) replacement therapy to weekly GH replacement therapy with somapacitan were evaluated and…
View details →Weldon K, O'Meara C, Lonergan P et al. · 2026 · Animal reproduction science
Extremolytes are compatible solutes that protect macromolecules and cell structures under extreme stress. The objectives of this study were to assess the biocompatibility of the extremolyte ectoine with bull sperm during cryopreservation,…
View details →Dialoke NG, Murata K, Zhang Y et al. · 2026 · The journal of poultry science
From an animal welfare perspective, thirst avoidance is an important criterion for the poultry industry. Neuropeptide Y (NPY) and α-melanocyte-stimulating hormone (α-MSH) play critical roles in regulating food intake, which is closely…
View details →Li F, Du C, Yu Q et al. · 2026 · Diabetes, obesity & metabolism
Aim Evaluate ecnoglutide (XW003) effects on rosuvastatin and digoxin pharmacokinetics (PKs) in healthy adults. Methods This was an open-label, single-sequence crossover Phase 1 study. Eligible participants received rosuvastatin (10 mg,…
View details →Matsuda S, Nakano K · 2026 · The Journal of eukaryotic microbiology
In Tetrahymena, autophagy appears to be involved in the integrity of the mitochondria which supply energy for active ciliary movement on the cell surface, the maintenance of various structures such as cilia, and cell shape changes…
View details →Lin M, Tapuc A, Matyjek M et al. · 2026 · Comprehensive psychiatry
Autistic traits are associated with atypical social behaviors, particularly in approach-avoidance tendencies. However, the differential impact of these traits on responses to social versus non-social stimuli, and the variation of these…
View details →Geng F, Guo R, Shao Y · 2026 · Journal of psychiatric research
Background The jumping-to-conclusions (JTC) bias, which involves making hasty decisions based on limited evidence, has been extensively studied in schizophrenia spectrum disorders but remains under-explored in affective disorders,…
View details →Khan H, Ghafoor T, Khattak TA et al. · 2026 · Transplantation and cellular therapy
Infantile Osteopetrosis is a rare inherited bone disorder characterized by a reduced or complete lack of osteoclast function, leading to defective bone resorption and increased bone density. The defective osteoclast differentiation or…
View details →Incerti Parenti S, Evangelisti E, Maglioni A et al. · 2026 · Cranio : the journal of craniomandibular practice
Objective To investigate whether fixed orthodontic treatment affects sleep and awake bruxism activities, temporomandibular disorder (TMD) prevalence, and pressure pain thresholds (PPTs) of masticatory muscles in healthy adults. Methods In…
View details →Jacob G, Lourenço PR, Diniz FMM et al. · 2026 · Journal of esthetic and restorative dentistry : official publication of the American Academy of Esthetic Dentistry ... [et al.]
Objective This study evaluated the effect of calcium hydroxide-based intracanal medication protocols on the sealer-dentin interface, considering bond strength, adhesive interface adaptation, failure pattern, and dentin gelatinolytic…
View details →Jian PT, Lin YW · 2026 · Contact dermatitis
Background Hairdressers often reuse disposable gloves, yet the effect of repeated washing on protection against oxidative hair-dye sensitizers is unclear. Objectives To determine how reuse and wash type influence the permeation of…
View details →Soares EADS, Crisp AH, Fernandes PT et al. · 2026 · Scandinavian journal of psychology
Premenstrual syndrome (PMS) is a set of symptoms related to hormonal changes occurring during the premenstrual period. Effective coping strategies for managing PMS have not been clearly established, and it remains unclear whether these…
View details →Mies F, Olchowik-Grabarek E, Crutzen R et al. · 2026 · Biochemical and biophysical research communications
In this report we demonstrate that iodogallic acid (IGA) and iodoferulic acid (IFA) do not acutely affect transepithelial cation transport, however, prolonged basolateral application of IFA induced a delayed decrease in open-circuit…
View details →Bodilsen TS, Andreasen TH, Olsen MH et al. · 2026 · Acta neurochirurgica
Background Invasive multimodal neuromonitoring (MMNM) is standard of care in many neuro-intensive care units for patients with severe acute brain injury. MMNM is used for monitoring of early signs of secondary brain injury. Still, the…
View details →Lindhard K, Hansen HP, Gliese K et al. · 2026 · Clinical journal of the American Society of Nephrology : CJASN
Introduction In patients on hemodialysis, the risk of arteriovenous fistula (AVF) failure is unacceptably high. Up to 67% of AVFs need an intervention within one year after placement. There are no effective treatments to prolong AVF…
View details →Goto K, Ishizuka S, Nakamura-Takahashi A et al. · 2026 · Journal of oral biosciences
Objectives Hypophosphatasia (HPP) is a congenital disease caused by mutations in the tissue non-specific alkaline phosphatase gene. HPP is characterized by impaired hard tissue mineralization and premature tooth loss. Mild-type HPP…
View details →Van Daele A, Labarque V, Dereymaeker A et al. · 2026 · Neuropediatrics
Background Neonatal stroke is a rare but potentially severe condition that may lead to long-term neurological impairment. Several factors may influence both its occurrence and outcomes. Methods In this retrospective, single-center cohort…
View details →Zeni NG, Perricone V, Tognoli C et al. · 2026 · Poultry science
The poultry sector faces increasing sustainability challenges related to feed-food competition, volatility in the cereal markets and the environmental impact of poultry production. In this context, the use of products from the bakery and…
View details →Flämig L, Felix Zhu W, Hoffmann K et al. · 2026 · Organic & biomolecular chemistry
Agonists of the κ-opioid receptor are useful drugs for the treatment of severe pain, itching skin diseases and inflammatory and immunological diseases. Herein, novel κ agonists with the κ-pharmacophoric ethylenediamine system embedded in a…
View details →Chiang YW, Chang JY, Yeh KL et al. · 2026 · Investigative ophthalmology & visual science
Purpose To investigate whether exposure to artificial lighting with different correlated color temperatures (CCTs) affects ocular structure and myopia-related molecular signaling pathways before axial elongation in a murine model. Methods…
View details →