Negative / Null Result ReportMedicine
Chang HH, Chun YM, Kim SJ et al. · 2026 · Arthroscopy : the journal of arthroscopic & related surgery : official publication of the Arthroscopy Association of North America and the International Arthroscopy Association
Purpose To compare clinical and radiologic outcomes among patients undergoing double-row suture bridge (DRSB) repair alone, DRSB with platelet-rich plasma (PRP) augmentation, and DRSB with bone marrow stimulation (BMS) augmentation.…
View details →Negative / Null Result ReportMedicine
El Ayat N, Boutalline M, Tannouche A · 2026 · BMC psychiatry
Background Autism Spectrum Disorder (ASD) affects 1 in 100 children globally, yet early detection remains challenging due to reliance on subjective behavioral assessments and limited specialist availability, particularly in…
View details →Negative / Null Result ReportMedicine
Schneider BS, Pfaehler CD, Hao KA et al. · 2026 · The Journal of the American Academy of Orthopaedic Surgeons
Background Although os acromiale is often noted on preoperative imaging in patients undergoing reverse total shoulder arthroplasty (rTSA), its clinical significance is ill-defined. The purpose of this study was to compare the clinical…
View details →Negative / Null Result ReportMedicine
Cacciatore S, Abbatecola G, Calvani R et al. · 2026 · Medical sciences (Basel, Switzerland)
Background/objectives Ozone therapy has been proposed across multiple clinical conditions based on hormetic, antioxidant, and immunomodulatory effects, but its efficacy and safety remain controversial. We conducted an umbrella review to…
View details →Negative / Null Result ReportMedicine
Maseroli E, Alfaroli C, Cirillo M et al. · 2026 · Journal of endocrinological investigation
Purpose To assess whether the Ketogenic Diet (KD) is associated with improvements in biochemical markers of hyperandrogenism in women diagnosed with Polycystic Ovary Syndrome (PCOS) with obesity or overweight. Methods A systematic search…
View details →Negative / Null Result ReportOpen accessMedicine
Belgioia L, D'Onofrio I, Filauro M et al. · 2026 · Acta otorhinolaryngologica Italica : organo ufficiale della Societa italiana di otorinolaringologia e chirurgia cervico-facciale
Objective To evaluate the impact of postoperative radiotherapy (PORT) on survival outcomes in patients with laryngeal cancer treated with partial laryngectomy. Methods In this retrospective multicentre study, 312 patients with supraglottic…
View details →Negative / Null Result ReportMedicine
Cui Y, Liu JL, Jiang CH et al. · 2026 · Diabetes, obesity & metabolism
Background Early dual antiplatelet therapy (DAPT) after intravenous thrombolysis is safe but ineffective in improving 90-day functional outcomes in minor stroke. Given the effect of diabetes mellitus (DM) with antiplatelet treatment, we…
View details →Negative / Null Result ReportMedicine
Chi SY, Chou SE, Chou FF et al. · 2026 · World journal of surgery
Background Thyroidectomy for Graves' disease (GD) is associated with an increased risk of intraoperative bleeding, particularly in patients with enlarged and hypervascular thyroid glands. This retrospective cohort study evaluated factors…
View details →Negative / Null Result ReportMedicine
Honda K, Furukawa S · 2026 · JASA express letters
This study addresses methodological issues in the modulation-masking paradigm for future clinical applications for assessing modulation filters. The aim of the paradigm is to determine a target-modulation threshold in a fixed-depth masker.…
View details →Negative / Null Result ReportMedicine
Hayes MW, Porter WM, Snider JL et al. · 2026 · Field Crops Research.
The rising cost of crop inputs has driven farmers to reduce costs. One area they have focused on is the seeding rate in an effort to minimize seed cost. Numerous studies have been completed every few years to evaluate optimum seeding rates…
View details →Negative / Null Result ReportMedicine
Goda S, Yamada T, Goto Y et al. · 2026 · BMC pulmonary medicine
Background The neutrophil-to-lymphocyte ratio (NLR) is a marker of systemic inflammation, with prognostic value in interstitial lung disease (ILD). However, the association between baseline NLR and the therapeutic efficacy of nintedanib…
View details →Negative / Null Result ReportMedicine
Esmeray A, Yazili HB, Gelmis M et al. · 2026 · The Canadian journal of urology
Objectives Supracostal access during percutaneous nephrolithotomy (PCNL) increases the risk of pulmonary complications. Although routine postoperative thoracic imaging is commonly performed to detect these events, its clinical necessity…
View details →Negative / Null Result ReportMedicine
Alhammadi S, Chalk C · 2026 · The Canadian journal of neurological sciences. Le journal canadien des sciences neurologiques
Myasthenia gravis (MG) is an autoimmune neuromuscular disorder characterized by fatigable weakness and increased perioperative vulnerability. Postoperative myasthenic crisis, defined as respiratory failure requiring prolonged ventilation…
View details →Negative / Null Result ReportMedicine
Tsukagoshi J, Penaloza N, Laico AJ et al. · 2026 · Annals of vascular surgery
Background While carotid endarterectomy (CEA) and carotid artery stenting (CAS) reduce the long-term risk of stroke, patients with a short life expectancy or multiple medical comorbidities, including end-stage renal disease (ESRD), may not…
View details →Negative / Null Result ReportMedicine
Davies F, Butler MK · 2026 · Eye (London, England)
Introduction This real-world, retrospective review of SLT outcomes at Lancashire Teaching Hospitals NHS Foundation Trust aimed to establish whether there is any net benefit in using topical drop treatment prior to SLT compared with…
View details →Negative / Null Result ReportOpen accessMedicine
Pellegrino N, Eliasziw M, Fortinsky R et al. · 2026 · Scientific reports
Exposure to particulate matter is associated with adverse health outcomes such as cardiovascular and neurological diseases. However, there are few intervention studies that have examined short-term changes in air particulate exposure and…
View details →Negative / Null Result ReportMedicine
Tlili S, Ben Mahfoudh H, Zoudji B · 2025 · Perceptual and motor skills
Generated drawing is a specific instructional approach that has been investigated in academic settings. However, in sports, tactical drawings are often presented based more on coaches' preferences than on empirical evidence. This study…
View details →Failed Experiment ReportMedicine
Schmidt ME, Gargano C, Zhou X et al. · 2026 · European neuropsychopharmacology : the journal of the European College of Neuropsychopharmacology
JNJ-42165279 is a potent, selective inhibitor of fatty acid amide hydrolase (FAAH), the enzyme responsible for degradation of the endocannabinoid N-arachidonoylethanolamide (anandamide), which plays a role in regulation of fear and anxiety…
View details →Negative / Null Result ReportMedicine
Scherer C, Fung V, Anzellini D et al. · 2026 · Breast cancer (Tokyo, Japan)
Background We report outcomes of patients who received intraoperative radiation therapy (IORT) using 50 kV after lumpectomy and sentinel lymph node biopsy. Methods Women with age > 45 and post-menopausal status, localized, unifocal,…
View details →Negative / Null Result ReportMedicine
Kanthar T, Vatcharavongvan P, Prasert V · 2025 · Journal of evaluation in clinical practice
Rationale The global prevalence rate of glaucoma blindness is extremely high and is a leading cause of irreversible blindness. Despite many advancements in treatment, evaluating glaucoma blindness remains challenging due to the long time…
View details →Negative / Null Result ReportMedicine
Blin P, Danchin N, Benichou J et al. · 2026 · American journal of cardiovascular drugs : drugs, devices, and other interventions
Introduction Antiplatelet therapy with low-dose aspirin, alone or as dual antiplatelet therapy (DAPT) with a P2Y 12 inhibitor, is used in secondary prevention following myocardial infarction (MI). However, the optimal duration of DAPT is…
View details →Negative / Null Result ReportMedicine
Romagnoli A, Marcellusi A, Lasala R · 2025 · Recenti progressi in medicina
Introduction Rapid access to safe and effective oncological therapies is crucial. In recent years, many expensive drugs have been commercialized, making it essential to prioritize those with significant clinical benefits. For this purpose,…
View details →Negative / Null Result ReportOpen accessMedicine
Yang M, Yang S, Zhang W et al. · 2026 · BMC cancer
AIM: The role of prophylactic hyperthermic intraperitoneal chemotherapy (HIPEC) in elderly patients with locally advanced colorectal cancer (LACRC) remains controversial. This study aimed to evaluate the perioperative safety and survival…
View details →Negative / Null Result ReportMedicine
Leggett CL, Plowman RS, Surace L et al. · 2026 · Gastrointestinal endoscopy
Background and aims Computer-aided polyp detection (CADe) systems can enhance polyp detection, although their performance has largely been evaluated at academic rather than community practices. This randomized controlled trial evaluated…
View details →Negative / Null Result ReportMedicine
Gupta Y, Baranwal M, Chudasama B · 2025 · Biotechnology journal
Despite the challenge in generating adequate immunogenicity, peptide-based vaccines offer a significant benefit in terms of improving immunity when combined with conjugates. In previous studies, three computationally designed immunogenic…
View details →Negative / Null Result ReportMedicine
Muste JC, Schulgit MJ, Perkins S et al. · 2026 · Ophthalmology. Retina
Objective To evaluate outcomes and complications of pars plana vitrectomy (PPV) for nonclearing vitreous hemorrhage (NCVH) secondary to proliferative diabetic retinopathy (DR) in the small-gauge, anti-VEGF era. Design Retrospective…
View details →Negative / Null Result ReportMedicine
Marzi Manfroni A, Scaccini OP, Ceccariglia F et al. · 2026 · Head & neck
Background Margin control is a crucial prognostic factor in head and neck oncological surgery. This retrospective case-control study aims to assess the superiority of computer-assisted surgery compared to traditional surgery in achieving…
View details →Negative / Null Result ReportOpen accessMedicine
Camilli M, Abbate A · 2026 · Cardio-oncology (London, England)
In cardio-oncology, the gap between mechanistic studies and pharmacological trials impedes the delineation of effective cardioprotective strategies. The angiotensin-receptor/neprilysin inhibitor (ARNI) have shown beneficial effects in…
View details →Negative / Null Result ReportMedicine
Lee J, Kim J, Lee K · 2026 · Journal of physical activity & health
Background Although previous studies have identified a positive relationship between physical activity (PA) participation and cognitive function in older adults, further research is needed to determine the level of PA necessary to…
View details →Negative / Null Result ReportOpen accessMedicine
Alvey E, Fielding L, Dennis D et al. · 2025 · Open veterinary journal
Background Intranasal lidocaine (LID) administration is a common treatment used to facilitate the passing of endoscopes and nasogastric tubes in horses. However, no research has supported its use in equine practice. Aim To compare patient…
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