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Browse the failure-mode index

12,244 real negative results, null findings, and replication failures in Medicine. Search the index →

WASTE indexes published research — it does not host or republish full papers. Each entry is a metadata record compiled from open scholarly databases; the abstract is shown in full only where the paper is openly licensed, otherwise a short excerpt under fair use. Classifications are automated and approximate.

Negative / Null Result ReportOpen accessMedicine

Effects of acute HMB-FA supplementation on antioxidant status and muscle damage in Elite Judoka: a randomized pilot trial.

Tayebi SM, Mirzaei M, Stout JR · 2026 · Journal of the International Society of Sports Nutrition

Purpose High-intensity judo bouts induce oxidative stress and muscle damage, impairing recovery. This randomized, double-blind, placebo-controlled pilot trial examined whether acute β -hydroxy- β -methylbutyrate free acid (HMB-FA)…

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Negative / Null Result ReportOpen accessMedicine

CO<sub>2</sub>-Extract-Based Phytopreparation from <i>Arctium tomentosum</i> Mill. Root Exhibits No Acute and Subacute Toxicity and Suppresses Xylene-Induced Ear Edema and LPS-Induced Acute Inflammation in Mice.

Aitynova A, Dyusebaeva M, Issayeva D et al. · 2026 · Molecules (Basel, Switzerland)

A phytopreparation based on the CO 2 extract of Arctium tomentosum Mill. root (AT) was evaluated for its safety and anti-inflammatory potential in Swiss albino mice. Acute and 28-day subacute oral toxicity studies demonstrated that AT, at…

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Negative / Null Result ReportMedicine

Parameter Specific Modulation of Neuronal Firing and Extracellular Action Potential Dynamics by Transcranial Focused Ultrasound Stimulation in Rat Motor Cortex.

Huang H, Smets C, Chen L et al. · 2026 · Brain stimulation

Background Transcranial focused ultrasound stimulation (TUS) has emerged as a promising tool for noninvasive neuromodulation. However, the specific effects of stimulation parameters on neural activity remain incompletely understood.…

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Negative / Null Result ReportMedicine

Exploring the Association of Religion and Religiosity on Mammography Screening Among White and Black Women: Results from the Brazilian Longitudinal Study of Aging (Elsi-Brazil).

Dias CS Jr, Verona AP, Leocádio V · 2026 · Journal of religion and health

This study examines the relationship between religious denomination, religious attendance, and mammography screening among White and Black women in Brazil, using baseline data from the Brazilian Longitudinal Study of Aging (ELSI-Brazil,…

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Negative / Null Result ReportMedicine

Effect of a 3.5 mm Tibial Plateau Leveling Osteotomy Locking Compression Plate on Serial Postoperative Tibial Plateau Angle Maintenance, Short-Term Osteotomy Healing, and Complication Rates in 45 to 70 kg Dogs.

Acuña J, Barnhart MD, Kennedy SC et al. · 2026 · Veterinary and comparative orthopaedics and traumatology : V.C.O.T

To evaluate the effect of a 3.5 mm tibial plateau leveling osteotomy (TPLO) locking compression plate on serial postoperative tibial plateau angle (TPA) maintenance, short-term osteotomy healing, and complication rates in dogs weighing 45…

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Negative / Null Result ReportMedicine

Investigation of Metabolites and Mineral Content in Blood Serum of Dairy Cows of the Simmental Breed in Samsun Province During the Transition Period.

Ormancı N, Bölükbaş B, Waqas M et al. · 2026 · Biological trace element research

This study evaluated the metabolic and mineral profiles in the blood serum of Simmental dairy cows during the transition period to assess their energy, protein, and mineral status. A total of 78 cows from 10 farms in Samsun Province were…

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Negative / Null Result ReportMedicine

How does organizational sacralization affect healthcare professionals' work engagement and turnover intentions through perceived organizational support?

Şengüllendi MF · 2026 · Journal of health organization and management

Purpose In recent years, the migration of healthcare professionals from developing countries to developed countries has accelerated. Türkiye is one of the countries negatively affected by the migration of healthcare professionals. This…

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Negative / Null Result ReportMedicine

Seems Like a Touch? Comparing Emotional Experience and Illusion of Touch of Visual and Haptic Presentations of Mediated Social Touch in VR.

Tietenberg J, Furtges T, Masuch M · 2026 · IEEE transactions on visualization and computer graphics

Social virtual reality (VR) applications enable users to experience highly immersive mediated interactions and social experiences. Especially embodied nonverbal communication, like mediated social touch, is mostly unique to social VR and…

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Negative / Null Result ReportMedicine

Exploring the impact of sleep apnea on renal transplant outcomes.

Satuluru S, Brower D, Mehta V et al. · 2026 · The American journal of the medical sciences

Background Sleep apnea (SA), a common diagnosis, has been shown to exhibit increased prevalence in patients with end-stage renal disease (ESRD). There is no clear consensus on the impact of SA on renal transplant outcomes. Methods We…

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Negative / Null Result ReportMedicine

Prewarming and thermal manipulation of long stored eggs: effect on embryonic development, hatching traits, body weight, rectal temperature, carcass, and organ traits at 3 days of age in broiler chickens.

Abdallah N, Baylan M, Kursun K et al. · 2026 · Journal of thermal biology

This study investigated the effect of prewarming (PD) and thermal manipulation (TM) of long-stored eggs on embryonic development, hatching traits, body weight (BW), rectal temperature (RT), carcass, and organ traits in broilers at 3 days…

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Negative / Null Result ReportOpen accessMedicine

Perfluorooctanoic acid (PFOA) induces lipid accumulation, oxidative stress, and reduced neurogenesis in primary human neuronal progenitor cells.

Marinello WP, Zylka MJ · 2026 · Frontiers in toxicology

Introduction Per- and polyfluoroalkyl substances (PFAS), particularly perfluorooctanoic acid (PFOA), are persistent environmental contaminants known for bioaccumulation and adverse health effects, including neurodevelopmental toxicity.…

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Replication FailureMedicine

Facial shape and self-perceived personality traits in young adults.

Gkantidis N, Tsikouriadou E, Halazonetis D et al. · 2026 · Scientific reports

The present study investigated the association between facial shape and self-perceived personality and psychosocial traits. The study population consisted of 613 young adults (399 females and 214 males) aged 21-35 years, with similar…

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