Negative / Null Result ReportOpen accessDiseases of the circulatory (Cardiovascular) system
Pankaj Puar, Nikhil Mistry, Kim A. Connelly et al. · 2023 · ESC Heart Failure
Abstract Aims Given recent suggestions that serum levels of insulin‐like growth factor‐binding protein 7 (IGFBP7) may identify patients who derive greater cardiorenal benefits from treatment with sodium‐glucose transport 2 inhibitors (SGLT2i), this exploratory sub‐analysis of the EMPA‐HEART CardioLink‐6 randomized controlled trial evaluated the association between serum levels of IGFBP7 and empagliflozin‐mediated left ventricular mass regression. Methods and results The EMPA‐HEART CardioLink‐6 trial used gold‐standard cardiac magnetic resonance imaging to detect change in left ventricular mass
View details →Negative / Null Result ReportOpen accessDiseases of the circulatory (Cardiovascular) system
Baravan Al-Kassou, Hasanin Al-Shaikh, Adem Aksoy et al. · 2023 · International Journal of Cardiology: Heart & Vasculature
Background: Vascular injury and bleeding complications remain frequent after transcatheter aortic valve replacement (TAVR). Whether the access-site of preprocedural coronary angiography (CAG) affects TAVR-related complications is not known. The aim of this study was to evaluate the impact of transradial (TRA) versus transfemoral access (TFA) for preprocedural CAG on outcomes in patients undergoing subsequent TAVR. Methods: The study cohort included 1002 patients undergoing transfemoral TAVR, of whom 39.4% (395/1002) had undergone radial and 60.6% (607/1002) femoral access for pre-TAVR CAG. The
View details →Negative / Null Result ReportOpen accessDiseases of the circulatory (Cardiovascular) system
Babak B. Navi, Mitchell S. V. Elkind, Cenai Zhang et al. · 2025 · Journal of the American Heart Association: Cardiovascular and Cerebrovascular Disease
Background Approximately 50% of strokes in patients with cancer are classified as cryptogenic after standard evaluation. Atrial cardiopathy could explain some cancer‐related cryptogenic strokes. However, the relationship between cancer and atrial cardiopathy is uncertain. Methods AND RESULTS We conducted a post hoc cross‐sectional analysis of baseline data collected from participants enrolled in ARCADIA (Atrial Cardiopathy and Antithrombotic Drugs in Prevention After Cryptogenic Stroke), a clinical trial conducted from 2018 to 2023 at 185 sites. The analytical cohort presented herein included
View details →Negative / Null Result ReportOpen accessDiseases of the circulatory (Cardiovascular) system
Shih-Hao Chen, Hung-Chieh Chang, Po-Wei Chiu et al. · 2023 · BMC Cardiovascular Disorders
Abstract Background Fever can occur after acute myocardial infarction (MI). The influence of body temperature (BT) after hospital arrival on patients with acute MI has rarely been investigated. Methods Patients who were diagnosed with acute MI in the emergency department (ED) of a tertiary teaching hospital between 1 January 2020 and 31 December 2020 were enrolled. Based on the tympanic temperature obtained at the ED triage, patients were categorized into normothermic (35.5°C-37.5°C), hypothermic ( 37.5°C) groups. The primary outcome was in-hospital cardiac arrest (IHCA), while the secondary o
View details →Negative / Null Result ReportOpen accessDiseases of the circulatory (Cardiovascular) system
Jing Zhang, Chengcheng Shao, Jiajia Zhu et al. · 2025 · Frontiers in Cardiovascular Medicine
BackgroundThis study investigated the clinical characteristics of in-hospital cardiac arrest (IHCA) in patients with acute myocardial infarction (AMI) complicated by cardiogenic shock and assessed the related in-hospital and post-discharge mortality.MethodsThis study included 148 patients with AMI complicated by cardiogenic shock who were admitted to the Cardiac Critical Care Center, Department of Cardiology, Beijing Anzhen Hospital, Capital Medical University between September 1, 2021 and July 31, 2024. Study participants were divided into two groups according to the occurrence of IHCA (IHCA
View details →Negative / Null Result ReportOpen accessDiseases of the circulatory (Cardiovascular) system
Oh Young Bang, Mi Ji Lee, Sookyung Ryoo et al. · 2015 · Journal of Stroke
Patent foramen ovale (PFO) is growing in clinical interest because of a renewed focus on embolic stroke of undetermined source (ESUS), the PFO attributable fraction (the 10-point Risk of Paradoxical Embolism score), technical advances in PFO diagnosis, and the emergence of endovascular device closure as a treatment option. However, recent randomized controlled trials of the management of patients with ESUS and PFO failed to demonstrate the superiority of closure over medical treatment. The mechanisms of stroke other than paradoxical embolism may be important in patients with ESUS and PFO. This
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