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Browse the failure-mode index

102 real negative results, null findings, and replication failures in Dentistry. Search the index →

WASTE indexes published research — it does not host or republish full papers. Each entry is a metadata record compiled from open scholarly databases; the abstract is shown in full only where the paper is openly licensed, otherwise a short excerpt under fair use. Classifications are automated and approximate.

Negative / Null Result ReportOpen accessDentistry

Evaluation of hardness and wear resistance of interim restorative materials

Omid Savabi, Farahnaz Nejatidanesh, Mohamad Hossein Fathi et al. · 2013 · Dental Research Journal

Background: The interim restorative materials should have certain mechanical properties to withstand in oral cavity. The aim of this study was to evaluate the hardness and wear resistance of interim restorative materials. Materials and Methods: Fifteen identical rectangular shape specimens with dimensions of 2 mm × 10 mm × 30 mm were made from 7 interim materials (TempSpan, Protemp 3 Garant, Revotek, Unifast LC, Tempron, Duralay, and Acropars). The Vickers hardness and abrasive wear of specimens were tested in dry conditions and after 1 week storage in artificial saliva. The depth of wear was

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Negative / Null Result ReportOpen accessDentistry

Effect of adhesive type and silane application on the repair bond strength of aged bulk-fill composites

Atefeh Yousefi Jordehi, Saeed Abdollahi, Ghazal Golshahirad et al. · 2025 · Journal of Dental Materials and Techniques

Objective: This study evaluated the effects of different adhesive strategies and silane application on the repair bond strength of bulk-fill composites.Methods: Seventy specimens were prepared using a bulk-fill condensable composite. After thermocycling, they were randomly divided into five groups (n = 14) based on the bonding protocol: Group 1: Gluma Bond 5 (two-step etch-and-rinse), Group 2: Silane + Gluma Bond 5, Group 3: Gluma Bond Universal (self-etch mode), Group 4: Silane + Gluma Bond Universal (self-etch mode), and Group 5: Gluma Bond Universal (etch-and-rinse mode). The repair process

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Negative / Null Result ReportOpen accessDentistry

Relationship between the Apical Preparation Diameter and the Apical Seal: An In Vitro Study

Kaoutar Laslami, Sara Dhoum, Amine El Harchi et al. · 2018 · International Journal of Dentistry

Objectives. The aim of the study is to define the relationship between the apical preparation diameter and the apical sealing ability to highlight the importance of the preservation of the diameter and the original position of the apical foramen. Materials and Methods. 50 extracted maxillary incisors were randomly allocated into three groups of 15 teeth each (n = 15) according to the apical preparation size: Group 1: finishing file F1 corresponding to size 20 reached the working length (ProTaper Universal system Dentsply®); Group 2: prepared up to size 30 corresponding to finishing file F30; G

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Negative / Null Result ReportOpen accessDentistry

Influence of Digit Sucking Habit on Masseter Muscle Thickness and Upper Airway Dimensions in Nigerian Children

Ada Njokanma, Olayinka Otuyemi, Kikelomo Kolawole · 2023 · Nigerian Dental Journal

Background: Digit sucking habit (DSH) generates functional forces that can influence craniofacial morphology. Although the dental effects have been widely reported, its influence on the masseter muscle thickness (MMT) and upper airway (UA) dimensions is not well known. Methods: Thirty (30) children selected from the orthodontic clinic (OAUTHC), with a DSH were matched with a group of 30 children without a DSH. Each group comprised of 16 males and 14 females. Ultrasonographic evaluation of the masseter muscle (MM) was performed to measure the left and right MMT in the relaxed and contracted sta

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Negative / Null Result ReportOpen accessDentistry

Sealing ability of a new calcium silicate based material as a dentin substitute in class II sandwich restorations: An in vitro study

Raji Viola Solomon, Parupalli Karunakar, Deepthi Sarvani Grandhala et al. · 2014 · Journal of Oral Research and Review

Background: Class ll sandwich restorations are routinely performed where conventional Glass ionomer cement (GIC) or Resin-modified GIC (RMGIC) is used as a base or dentin substitute and a light curing composite resin restorative material is used as an enamel substitute. Various authors have evaluated the microleakage of composite resin restorations where glass ionomer cement has been used as a base in class II sandwich restorations, but a literature survey reveals limited studies on the microleakage analysis of similar restorations with biodentine as a dentin substitute, as an alternative to g

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Negative / Null Result ReportOpen accessDentistry

Shear Bond Strength of Universal Adhesives with Different Methods of Zirconia Ceramic Preparation after Thermocycling: A Laboratory Study

Ebrahim Yarmohammadi, Shiva Kavousinejad · 2024 · Journal of Dental School

Objectives The present study aimed to assess the level of shear bond strength (SBS) of universal adhesives (G-premio Bond Universal (GBU) and All Bond Universal (ABU) on zirconia without surface preparation, zirconia sandblasted by 50-micron aluminum oxide particles, and zirconia glazed by low-fusing ceramics after the thermocycling process. Methods Two Ceramill ZI zirconia blocks were used to prepare 18 cubes with dimensions of 10×10×10 mm. Then, based on the type of surface preparation, these 18 sintered zirconia cubes were classified into three groups of six, including the control group, sa

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Negative / Null Result ReportOpen accessDentistry

In Vitro Evaluation of the Effect of Different Sandblasting Times on the Bond Strength of Feldspathic Porcelain to Composite Resin

Ebrahim Amin Salehi, Haleh Heshmat, Elham Moravej Salehi et al. · 2013 · Journal of Islamic Dental Association of Iran

Background and Aim: Intraoral repair of fractured porcelain is an acceptable method to avoid replacement and therefore saving time and cost. The purpose of this study was to determine the in-vitro shear bond strengths of composite resin to feldspathic porcelain after different durations of sandblasting and to compare the effect of sandblasting with that of hydrofluoric acid (HF ). Materials and Methods : In this in-vitro study, 40 porcelain disks were fabricated and randomly divided into 4 groups (n=10). Porcelain surface in group 1 was etched with 9.5% HF for 2 minutes. Groups 2, 3 and 4 were

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Negative / Null Result ReportOpen accessDentistry

Marginal gap of zirconia and lithium disilicate frameworks produced by the CAD-CAM technique through a comparator microscope – in vitro analysis

Ellen Christine Rodrigues Abreu, Vicente Colussi Ferreira , Karina Andrea Novaes Olivieri et al. · 2024 · Brazilian Dental Science

Objective: The aim of this study was to evaluate the marginal gap of frameworks produced using the CAD-CAM system, from zirconia and lithium disilicate blocks, adapted to a tooth preparation and a gypsum die. Material and Methods: For this study, a human first molar tooth was used as a master model with a full crown preparation. It was molded 20 times to obtain the gypsum die and randomly divided into 2 groups (n=10) for the fabrication of zirconia and lithium disilicate frameworks. The frameworks were made using pre-sintered zirconia blocks and lithium disilicate blocks, both CAD-CAM systems.

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Negative / Null Result ReportOpen accessDentistry

Minimal alterations on the enamel surface by micro-abrasion: in vitro roughness and wear assessments

Marcela Charantola Rodrigues, Rafael Francisco Lia Mondelli, Gabriela Ulian Oliveira et al. · 2013 · Journal of Applied Oral Science

Objective: To evaluate the in vitro changes on the enamel surface after a micro-abrasion treatment promoted by different products. Material and Methods: Fifty (50) fragments of bovine enamel (15 mm × 5 mm) were randomly assigned to five groups (n=10) according to the product utilized: G1 (control)= silicone polisher (TDV), G2= 37% phosphoric acid (3M/ESPE) + pumice stone (SS White), G3= Micropol (DMC Equipment), G4= Opalustre (Ultradent) and G5= Whiteness RM (FGM Dental Products). Roughness and wear were the responsible variables used to analyze these surfaces in four stages: baseline, 60 s an

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Negative / Null Result ReportOpen accessDentistry

Genotoxicity effects of nano bioactive glass and Novabone bioglass on gingival fibroblasts using single cell gel electrophoresis (comet assay): An in vitro study

Mohammad Tavakoli, Ensiyeh Bateni, Mansour Rismanchian et al. · 2012 · Dental Research Journal

Background: The greater surface of bioactive glass nanoparticles presents an incomparable and promising feature similar to the biological apatite. Nanoparticles improve cellular adhesion, enhance osteoblast proliferation and differentiation, and increase biomineralization for periodontal regeneration and dental implants. Considering the fact that interaction between periodontal cells and bone graft materials are important for periodontal lesion regeneration, the present study was undertaken to investigate the genotoxicity of a novel synthesized nanoscale bioactive glass and compared it with No

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Negative / Null Result ReportOpen accessDentistry

Correlation of CD10 immunoexpression and eosinophil count in stromal tissue as predictors of prognosis of squamous cell carcinoma of the oral cavity

Deece Patuti, Harmas Yazid Yusuf, Bethy Suryawathy Hernowo · 2010 · Padjadjaran Journal of Dentistry

Introduction: CD10 can also facilitate the ability of tumour metastasis by its ability to invade blood vessel walls.Correlation of CD10 immunoexpression and eosinophil count in stromal tissue as predictors of prognosis of squamous cell carcinoma of the oral cavity. Methods: This study was preceded by collecting data on squamous cell carcinoma of the oral cavity in the medical record and paraffin blocks in the Anatomy Pathology section of 15 samples with enlarged regional lymph nodes and 15 samples without enlargement of regional lymph nodes. Then two preparations were made, the first preparati

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Failed Experiment ReportOpen accessDentistry

Evaluating the effectiveness of advanced platelet-rich fibrin, photobiomodulation, pentoxifylline, and Alveogyl in the treatment of alveolar osteitis: a randomized controlled clinical trial

Alper Yuzbasioglu, Cennet Neslihan Eroglu · 2024 · BMC Oral Health

Abstract Background Alveolar osteitis is a type of small-scale osteomyelitis of the alveolar bone that occurs after tooth extraction, the etiology of which remains unknown, and alternative methods are being investigated for its treatment. The aim of this study was to compare the effectiveness of advanced platelet-rich fibrin (A-PRF), photobiomodulation (PBM), and Alveogyl (butamben, idoform, eugenol), which have shown success in the treatment of alveolar osteitis, with that of pentoxifylline (PTX) to determine whether PTX could be an alternative treatment for alveolar osteitis. Methods This st

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Negative / Null Result ReportOpen accessDentistry

Addition of bone morphogenetic protein type 2 to ascorbate and -glycerophosphate supplementation did not enhance osteogenic differentiation of human adipose-derived stem cells

Ariadne Cristiane Cabral Cruz, Mariana Lúcia Silva, Thiago Caon et al. · 2012 · Journal of Applied Oral Science

Bone morphogenetic protein type 2 (BMP-2) is a potent local factor, which promotes bone formation and has been used as an osteogenic supplement for mesenchymal stem cells. OBJECTIVES: This study evaluated the effect of a recombinant BMP-2 as well as the endogenous BMP-4 and BMP-7 in the osteogenic differentiation of adipose-derived stem cells (ASCs) in medium supplemented with ascorbate and -glycerophosphate. MATERIAL AND METHODS: Human ASCs were treated with osteogenic medium in the presence (ASCs+OM+BMP-2) or absence (ASCs+OM) of BMP-2. The alkaline phosphatase (ALP) activity was determined

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Negative / Null Result ReportOpen accessDentistry

Effect of addition of polymerized polymethyl methacrylate (PMMA) and zirconia particles on impact strength, surface hardness, and roughness of heat cure PMMA: An in vitro study

Duaa Subhi Rasan, Firas Abdulameer Farhan · 2023 · Dental Hypotheses

Introduction: This study was designed to examine the effects of addition of the combination of polymerized polymethyl methacrylate (PMMA) and zirconia (ZrO2) particles to heat cure PMMA resin on impact strength, surface hardness, and roughness. Methods: The 70% (w/w) of polymerized PMMA powder (particle size: 0.70 µm) was mixed with 30% (w/w) of zirconia powder (ZrO2) (1 µm) to produce PMMA-ZrO2 filler. Ninety acrylic specimens created were divided into three groups containing 0% wt (Control group), 2% wt, and 4% wt, PMMA-ZrO2 filler. Ten specimens were used for impact strength, surface hardne

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Negative / Null Result ReportOpen accessDentistry

Morphological and dimensional characteristics of dental arch in children with beta thalassemia major

Disha Kumar, Anant Gopal Nigam, Nikhil Marwah et al. · 2018 · Journal of Indian Society of Pedodontics and Preventive Dentistry

Background and Objectives: The aim of this study was to examine the arch dimensions of beta thalassemia major patients in comparison with normal individuals. Materials and Methods: Dental arch dimensions were compared between thalassemic patients and normal individuals in the age group of 12–16 years in the maxillary and mandibular arch corresponding to each other regarding age, sex and Angle's molar relationship. A total number of sixty cases in each group were taken. Maxillary and mandibular impressions were made with alginate for all the sixty participants in each group and poured with die

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Negative / Null Result ReportOpen accessDentistry

Biofilm forming capacity of Enterococcus faecalis on Gutta-percha points treated with four disinfectants using confocal scanning laser microscope: An in vitro study

Polavarapu Venkata Ravi Chandra, Vemisetty Hari Kumar, Surakanti Jayaprada Reddy et al. · 2015 · Dental Research Journal

Background: The aim of this study was to evaluate and compare the in vitro biofilm forming capacity of Enterococcus faecalis on Gutta-percha points disinfected with four disinfectants. Materials and Methods: A total of 50 Gutta-percha points used in this study were divided into four test groups based on disinfectant (5.25% sodium hypochlorite, 2% chlorhexidine gluconate, 20% neem, 13% benzalkonium chloride [BAK]), and one control group. The Gutta-percha points were initially treated with corresponding disinfectants followed by anaerobic incubation in Brain Heart Infusion broth suspended with h

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Negative / Null Result ReportOpen accessDentistry

Orthodontic treatment outcomes obtained by application of a finishing protocol

Alvaro Carvajal-Flórez, Diana María Barbosa-Lis, Oscar Arturo Zapata-Noreña et al. · 2016 · Dental Press Journal of Orthodontics

ABSTRACT Objective: To evaluate the results of a finishing protocol implemented in patients treated in the Orthodontics graduate program at Universidad de Antioquia. Evaluation was carried out by means of the criteria set by the Objective Grading System (OGS) of the American Board of Orthodontics (ABO). Methods: Cast models and panoramic radiographs of 34 patients were evaluated. The intervention group (IG) consisted of 17 patients (19.88 ± 4.4 years old) treated under a finishing protocol. This protocol included training in finishing, application of a finishing guide, brackets repositioning a

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Negative / Null Result ReportOpen accessDentistry

Influence of film thickness of one and two-step universal adhesives on dentin bond strength

Selin Yalnız, Hayal Boyacıoglu, Lezize Sebnem Turkun · 2026 · BMC Oral Health

Abstract Background To investigated the combined effect of adhesive type and film thickness on dentin bond strength by comparing one and two-step universal adhesives applied in single and double layers. Methods Forty caries-free human third molars were collected and standardized Class I cavities were prepared. Specimens were restored using one-step (Clearfil Tri-S Bond Universal, Japan) and two-step (G2-Bond Universal, Japan) universal adhesive systems. Each group was subdivided into single and double-layer applications, light-cured, and restored with a universal composite resin. Sticks with a

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Negative / Null Result ReportOpen accessDentistry

The association between sedentary behavior and obstructive sleep apnea: a cross-sectional study from the NHANES (2007–2008 to 2015–2020)

Song Cai, SiYu Li, YaShi Zhou et al. · 2024 · BMC Oral Health

Abstract Background Sedentary behavior (SB) may contribute to obesity and lower extremity fluid retention, which may favor the development of obstructive sleep apnea (OSA). However, linking sedentary behavior to OSA is unclear. The purpose of this study was to determine if there is an association between SB and OSA. Methods Three typical questions in the NHANES questionnaire(①The frequency of feeling excessively sleepy per month. ②The frequency of gasping, snorting or stopping breathing per week. ③The frequency of snoring per week.) have been used for the assessment of OSA. A physical activity

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Negative / Null Result ReportOpen accessDentistry

Bell’s Palsy: A Prospective Study

Ahmed Hassan Kamil Mustafa, Ahmed Mohammed Suleiman · 2020 · International Journal of Dentistry

Background. Bell’s palsy is an acute idiopathic facial nerve paralysis of sudden onset. It is the most common cause of lower motor neuron facial nerve paralysis with an annual incidence of 15–30 per 100,000 population. The objective of this work is to study the grade of the attack and the associated symptoms of Bell’s palsy in a group of Sudanese patients. The study type is an analytical prospective-based study. The study was carried out at Khartoum Teaching Dental Hospital, Khartoum General Teaching Hospital. In this prospective of the study, 48 patients with Bell’s palsy were evaluated using

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Negative / Null Result ReportOpen accessDentistry

Effect of a metal artifact removal algorithm on visibility of the second mesiobuccal canal of maxillary molars on cone-beam computed tomography scans: multilevel mixed-effects ordered logistic regression

Hamed Kalhor, Mamak Adel, Maryam Tofangchiha et al. · 2026 · Annali di Stomatologia

Objectives: This study aimed to assess the effect of a metal artifact removal (MAR) algorithm on the visibility of the second mesiobuccal canal (MB2) of maxillary molars on cone-beam computed tomography (CBCT) scans. Materials and Methods: This cross-sectional study evaluated 41 CBCT scans of patients retrieved from the radiology clinic’s archives. The CBCT scans were saved with and without the MAR algorithm applied. The images were coded and evaluated by two endodontists to assess MB2 detection in maxillary molars and its visibility level using a 5-point Likert scale. Of the 164 samples, 32 w

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Negative / Null Result ReportOpen accessDentistry

Comparison of Shear Bond Strengths of Orthodontic Brackets Bonded with Three Different Curing Techniques

Hakan Türkkahraman, Cenker Küçükeşmen · 2005 · Turkish Journal of Orthodontics

The aim of our study was to compare shear bond strengths of orthodontic brackets bonded with chemically cured, halogen light cured and LED cured adhesive systems. 45 extracted human premolar teeth were randomly divided into 3 groups. Bicuspid metal brackets were bonded on first group of teeth with chemically cured bonding system (Rely-a-Bond). Second group were bonded with halogen light cured bonding system (Light Bond). Last group were bonded with LED light cured bonding system (Light Bond). Each specimen was then loaded to universal testing machine. Bond strength was determined in the shear

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Negative / Null Result ReportOpen accessDentistry

The association between oral inflammatory load and semen and sperm functional analysis: A cross-sectional study

Reza Pourabbas, Samin Farajzadeh, Amirreza Babaloo et al. · 2023 · Journal of Dental Research, Dental Clinics, Dental Prospects

Background. Studies have suggested a correlation between periodontitis and reduced male fertility. Inflammation has been described as the link between these ailments. Oral inflammatory load (OIL) can be measured through oral polymorphonuclear neutrophil (oPMN) count, which is associated with periodontal diseases. This cross-sectional study assessed the possible correlation between OIL and the functional parameters of sperm cells. Methods. In 229 volunteers, oral rinse and semen samples were assessed for oPMN, semen polymorphonuclears (sPMNs), sperm concentration, total sperm count, motility, m

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Negative / Null Result ReportOpen accessDentistry

Oral Health Related Quality of Life of Patients Using Conventional Dentures versus Implant-Supported Overdentures

Ramtin Azar, Hassan Semyari, Mohamad Javad Kharazifard · 2020 · Frontiers in Dentistry

Objectives: This study aimed to compare the oral health related quality of life (OHRQoL) of patients using conventional dentures versus implant-supported overdentures. Materials and Methods: This study evaluated the OHRQoL of 90 patients between 35 to 75 years who were selected from several public and private dental clinics in Tehran in 2018. Of all, 45 had conventional dentures of both jaws, and 45 had a mandibular overdenture supported by two implants at the site of mandibular canine teeth and a conventional maxillary denture. The OHRQoL of patients was determined using the Oral Health Impac

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Negative / Null Result ReportOpen accessDentistry

The keratinized mucosa width at partially edentulous molar sites and its associated factors: a pilot study

Ziyao Han, Cui Wang, Yiping Wei et al. · 2022 · BMC Oral Health

Abstract Background Assessment of the keratinized mucosa width (KMW) at edentulous sites is important for the subsequent implant treatment design. This pilot study aimed to evaluate the characteristics of the KMW at edentulous molar sites and explore the associated factors. Methods A total of 150 patients with 222 edentulous molar sites were included. The buccal KMW of the edentulous molar sites was measured during implant treatment planning. Potentially associated factors, including age, sex, smoking status, location, reasons for tooth loss/extraction, gingival phenotype (GP) and keratinized

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Negative / Null Result ReportOpen accessDentistry

Musculoskeletal disorders in upper limbs in dental students: exposure level to risk factors

Patrícia Petromilli Nordi Sasso Garcia, Camila Pinelli, Juliana dos Reis Derceli et al. · 2015 · Brazilian Journal of Oral Sciences

Aim: This study assessed the risk factors of undergraduate students to develop musculoskeletal disorders (MSD) in the upper limbs, regarding gender, type of dental clinical procedure, mouth region treated, and the four-handed dentistry practice. Methods: Dental students enrolled in the 8th semester in the Araraquara School of Dentistry, UNESP, Brazil, were photographed while practicing 283 dental procedures. The Rapid Upper Limb Assessment (RULA) method was used to evaluate the working postures of each student. The photographs were evaluated and a final risk score was attributed to each analyz

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Negative / Null Result ReportOpen accessDentistry

Is there any Association between Dental Caries and Body Mass Index among 8–10 Years Pediatric Clinic Attenders in Chandigarh Area? A Correlation Study

Leena Verma, Ravi Sharma, Sidhi Passi et al. · 2023 · Journal of South Asian Association of Pediatric Dentistry

Aim: To evaluate the correlation between dental caries and obesity in 8–10 years school children of Chandigarh, India. Materials and methods: Around 100 children of the age range of 8–10 years who attended the Pediatrics OPD of Dr Harvansh Singh Judge Institute of Dental Sciences & Hospital, Chandigarh, India were selected. Four groups were made group I—25 healthy teeth and nonobese (HNO) children, group II—25 carious teeth and nonobese (CNO) children, group III—25 healthy teeth and obese (HO) children, and group IV—carious teeth and obese (CO) children. Caries score was recorded after careful

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Negative / Null Result ReportOpen accessDentistry

Correlation between salivary zinc levels and salivary volume on taste disorders in elderly patients

Dewi Kania Intan Permatasari, Tenny Setiani Dewi, Dewi Marhaeni Diah Herawati · 2021 · Dental Journal

Background: Taste disorders often occur in the elderly, which can have serious consequences on their health status. Zinc and saliva volume have a role in maintaining taste acuity, especially in the elderly. Purpose: This study was to determine the correlation between salivary zinc levels, salivary volume, and taste disorders in elderly patients. Methods: This was a cross-sectional research. Elderly patients with and without taste disorders were included in this study. Salivary zinc levels were measured using the Atomic Absorption Spectrometry (AAS) method. Salivary volume was measured using th

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Negative / Null Result ReportOpen accessDentistry

Evaluation of tongue/mandible volume ratio in children with obstructive sleep apnea

Kavita Hotwani, Krishna Sharma, Arpan Jaiswal · Dental Press Journal of Orthodontics

ABSTRACT Objective: The present study was an attempt to investigate tongue/mandible volume ratio in children, using volumetric magnetic resonance imaging (MRI) for early screening and to aid in treatment planning. Methods: Volumetric evaluation of tongue volume/mandible volume ratio (TV/MV ratio) in children with obstructive sleep apnea (OSA) using MRI was carried out retrospectively on available DICOM MR images of children in the age group of 10-14 years. MRI image records of patients diagnosed with OSA were obtained from interventional radiology department records, at Sharad Pawar Dental Col

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Negative / Null Result ReportOpen accessDentistry

Examination of gutta-percha cones for microbial contamination during chemical use

Guven Kayaoglu, Mügem Gürel, Hüma Ömürlü et al. · 2009 · Journal of Applied Oral Science

OBJECTIVE: The aim of this study was to evaluate the degree of microbial contamination in packaged gutta-percha cones before and during use in clinical conditions. MATERIAL AND METHODS: Sealed packages of #15-40 gutta-percha cones were opened under aseptic laboratory conditions. Two gutta-percha cones from each size were randomly drawn and added to tubes containing glass beads and 750 µL of saline. The tubes were vortexed, serially diluted and samples of 250 µL were cultured on agar plates. The plates were incubated at 37ºC for 3 days and colonies were counted. The initially sampled packages w

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