12,244 real negative results, null findings, and replication failures in Medicine. Search the index →
WASTE indexes published research — it does not host or republish full papers. Each entry is a metadata record compiled from open scholarly databases; the abstract is shown in full only where the paper is openly licensed, otherwise a short excerpt under fair use. Classifications are automated and approximate.
Gao R, Zhang X, Li G et al. · 2026 · BMC cancer
Background Betel nut chewing (BNC) is a prevalent risk factor for oral squamous cell carcinoma (SCC) in South and Southeast Asia, yet its influence on response to neoadjuvant immunochemotherapy remains unexplored. This study aimed to…
View details →Yoon S, Chang Y, Chang OD et al. · 2026 · Child maltreatment
Understanding how protective factors and strengths operate to promote positive youth development is critical for supporting youth who have experienced childhood maltreatment. Guided by the Resilience Portfolio Model, including the…
View details →Çelik B, İşevi C, Pirzirenli MG et al. · 2026 · The Journal of surgical research
Introduction This study evaluated the effect of preoperative smoking cessation duration on postoperative complications after lung cancer surgery. Materials and methods In this single-center prospective cohort study, 156 patients undergoing…
View details →Eraghi NG, Sefati N, Ghaffari MK et al. · 2026 · Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association
Alcohol Use Disorder (AUD) is a complex condition marked by physical and psychological dependence, often accompanied by lasting changes in brain regions such as the hippocampus that contribute to memory and cognitive impairments. Emerging…
View details →Umutoni V, Eavou R, Almirol E et al. · 2026 · Journal of acquired immune deficiency syndromes (1999)
Background Black and Hispanic/Latino sexual gender minorities are disproportionately affected by HIV. Structural determinants of health, such as health insurance coverage, drive care engagement and improve HIV care outcomes. Methods Black…
View details →Rusu RV, Rusu DO, Delcea C · 2026 · Behavioral sciences (Basel, Switzerland)
Adverse childhood experiences (ACEs) have been associated with increased vulnerability to depressive symptoms during pregnancy and may also be related to emerging prenatal relational processes. This cross-sectional study examined whether…
View details →Friedrich L, Walgenbach M, O Connor M et al. · 2026 · Journal of interventional cardiac electrophysiology : an international journal of arrhythmias and pacing
BACKGROUND: Left ventricular lead (LVL) implantation can be challenging in Cardiac Resynchronization Therapy (CRT). Therefore, contrast is commonly used to visualize the coronary venous system. However, contrast use is correlated with…
View details →Barrett AE, Soulie B, Mimbs H et al. · 2026 · International journal of aging & human development
Drowsy driving is a major cause of motor vehicle injuries and fatalities, yet little is known about its impact on older adults. This group may face heightened risk due to age-related sleep issues. Using survey data from 3,411 Floridians…
View details →Garrido-Castro AC, Graham N, Li KX et al. · 2026 · Nature communications
This multi-institutional randomized phase II clinical trial (NCT03414684) investigated the efficacy and safety of carboplatin plus nivolumab compared to carboplatin in metastatic triple-negative breast cancer (mTNBC). The primary endpoint…
View details →Tomoi Y, Takahara M, Soga Y et al. · 2026 · Journal of cardiology
Background Although sodium-glucose cotransporter-2 inhibitors (SGLT2i) are recommended for patients with diabetes mellitus (DM) and peripheral artery disease (PAD), their effects on limb-related outcomes remain uncertain, and their use…
View details →Karaca BŞ, Alşen Güney S · 2026 · Child neuropsychology : a journal on normal and abnormal development in childhood and adolescence
This study examined the association between caregiver anxiety, ADHD symptom severity, and metacognitive awareness in children with attention-deficit/hyperactivity disorder (ADHD), and evaluated whether metacognitive awareness mediates the…
View details →Kim HC, Park KJ · 2026 · Physical therapy in sport : official journal of the Association of Chartered Physiotherapists in Sports Medicine
Objectives To evaluate the effect of the 'Get Set-Train Smarter' warm-up program on injury incidence, type, and severity in elite Adolescent and Young Adult (AYA) Taekwondo athletes. Design Cluster-randomized controlled trial. Setting…
View details →Zhao T, Dewitte L, McKenna-Plumley PE et al. · 2026 · Psychological reports
Existential isolation (EI) has been linked to depressive symptoms, yet evidence suggests it is not always distressing and can be meaningful for some individuals by satisfying their desire for uniqueness. To explore the mechanism between EI…
View details →Tian W, Wang Y, Wang Y · 2026 · Acta psychologica
Inclusive education, extending beyond classroom access to emphasize affective support, equitable participation, and learner diversity, frames this study of university English as a foreign language (EFL) learning in the age of artificial…
View details →Sari O, Ure UB · 2026 · JPMA. The Journal of the Pakistan Medical Association
To assess data on transfusion requirements and burdens after autologous stem cell transplantation for haematological malignancy, and to investigate the impact of transfusion requirements and burdens on patient survival outcomes. The…
View details →Veternik M, Simera M, Martvon L et al. · 2026 · Respiratory physiology & neurobiology
Cough and expiration reflex (ER) are two fundamental airway defense mechanisms traditionally considered distinct motor behaviors. This study examined their temporal and functional interaction using an anesthetized cat model to elucidate…
View details →Bellout H · 2026 · Investigational new drugs
A common, often unstated paradigm in T-cell engager (TCE) translation assumes that target-antigen density and drug exposure are the main efficacy drivers, with effector context secondary. This paradigm is visible in dose-escalation…
View details →Yue J, Kim KO, Yeo YH · 2026 · Frontiers in psychology
Introduction As public services in South Korea rapidly digitalize, adults with disabilities remain at heightened risk of digital exclusion beyond access barriers. This study aims to identify joint profiles of digital attitudes and digital…
View details →Park S · 2026 · Journal of the Air & Waste Management Association (1995)
In recent years, environmental policies aimed at reducing the use of plastic bags have received considerable attention. However, few studies have investigated whether these policies can effectively reduce vinyl waste generation over time.…
View details →Chabbert MC, Voillequin S, Hot N et al. · 2026 · Midwifery
Objective To determine the psychological factors associated with antenatal depressive symptoms and to assess whether psychological flexibility moderates the relationship between negative anticipation and fear of childbirth and depressive…
View details →Tayeva A, Kulazhanov T, Dikhanbayeva F et al. · 2026 · Foods (Basel, Switzerland)
Iodine deficiency remains a major nutritional concern worldwide, and fermented dairy products are considered promising vehicles for iodine fortification. However, the chemical form of iodine may influence the physicochemical and…
View details →Hong JW, Bright T, Tucker C et al. · 2026 · JCO oncology practice
Purpose Taxanes are associated with a higher incidence of immediate hypersensitivity reactions (HSRs) compared with other classes of chemotherapeutic agents, even with premedication. This study evaluates whether a titrated infusion…
View details →Zheng S, Shi Y, Feng Z et al. · 2026 · Journal of wound care
Objective The efficacy of acellular dermal matrix (ADM) in immunocompromised patients' wounds has been little studied. The present study aimed to determine the wound healing effects of ADM in immunocompromised patients compared with…
View details →Olejua P, McLain AC, Ghosal R et al. · 2026 · Parkinsonism & related disorders
Introduction Postural instability and gait dysfunction (PIGD) subtype of PD has been associated with a more rapid progression of cognitive and motor dysfunction while tremor dominant (TD) subtype is associated with more severe tremors and…
View details →Portell AL, Niec LN · 2026 · Behavior modification
Time-out from positive reinforcement (TOPR) is an effective limit-setting strategy for decreasing disruptive behaviors in young children. However, most publicly available information on TOPR (e.g., social media and other internet outlets)…
View details →Khury F, Antonioli S, Ruff G et al. · 2026 · European journal of orthopaedic surgery & traumatology : orthopedie traumatologie
Background Testosterone replacement therapy (TRT) may cause side effects after orthopedic procedures. With total hip arthroplasty (THA) rates increasing, this study evaluates the relationship between TRT and postoperative complications in…
View details →Prado GFA, de PB, Dias SG et al. · 2026 · EuroIntervention : journal of EuroPCR in collaboration with the Working Group on Interventional Cardiology of the European Society of Cardiology
Background Whether the anatomical complexity of percutaneous coronary intervention (PCI) in acute coronary syndromes (ACS) influences the effects of antiplatelet therapy remains unknown. Aims We aimed to evaluate the impact of coronary…
View details →Young TJ, Eckert TL, Burke SE · 2026 · School psychology (Washington, D.C.)
Acceptability, defined as the perception that an intervention is appropriate, fair, and reasonable, is crucial to assess during implementation (Kazdin, 1981). Despite its original conceptualization as a dynamic process, repeated…
View details →Mechdoud S, Berton Q, Arrighi M et al. · 2026 · Archives de pediatrie : organe officiel de la Societe francaise de pediatrie
Background Few studies have examined the quality of life (QOL) of children undergoing surgery for non-syndromic craniosynostosis (NSC), with no age-specific assessment in France. Objective The CRANIOQUALITY study aimed to assess QOL across…
View details →Jovanovic K, Jovanovic N, Dabovic L et al. · 2026 · Annals of vascular surgery
Objective To assess the predictive value of neutrophil-to-lymphocyte ratio (NLR), platelet-to-lymphocyte ratio (PLR), and systemic inflammatory response index (SIRI), for short-term morbidity and mortality in patients undergoing ruptured…
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