Replication FailureMedicine
Van Brussel L, Geurden T · 2026 · Ticks and tick-borne diseases
Background Rapid and high efficacy against ticks after attachment has the potential to aid in the prevention of tick-borne pathogen transmission. The objective of the study was to assess the speed-of-kill of Simparica Trio® against Ixodes…
View details →Negative / Null Result ReportOpen accessMedicine
Leal Barbosa V, Westenhofen D, Scherdien Silva P et al. · 2026 · Lasers in medical science
Purpose To evaluate the efficacy of 8% arginine-based desensitizing toothpaste and photobiomodulation (PBM), used alone or in combination, in the treatment of dentin hypersensitivity (DH). Materials and methods This randomized,…
View details →Negative / Null Result ReportMedicine
van Lohuizen Q, Fransen SJ, Yiasemis G et al. · 2026 · European radiology
Objectives To determine whether AI-reconstructed prostate MRI at reduced acquisition times maintains prostate cancer (PCa) detection performance comparable to conventional scans. Materials and methods This multicenter, retrospective,…
View details →Negative / Null Result ReportMedicine
Akay T, Arslan RS · 2026 · Scientific reports
Patients with deep perianal abscess (DPA) and transsphincteric fistula typically require incision and drainage as emergency treatment. However, recurrent abscesses and fistulas are common. This study aimed to evaluate the impact of…
View details →Negative / Null Result ReportMedicine
Verhulst E, Ten Broek R, Bislenghi G et al. · 2026 · Techniques in coloproctology
Postoperative intraabdominal adhesions remain one of the most common and clinically significant complications following abdominal and pelvic surgery. Adhesions contribute to adhesive small bowel obstruction (aSBO), chronic abdominal pain,…
View details →Negative / Null Result ReportMedicine
Ichie K, Asomugha A, Okafor I · 2026 · BMC neuroscience
Background Parkinson's disease (PD) is a progressive neurodegenerative disorder strongly associated with dopaminergic neuronal degeneration and alpha-synuclein pathology. Paraquat (PQ) has been implicated in Parkinsonian neurodegeneration;…
View details →Negative / Null Result ReportMedicine
Somerville E, Bollinger RM, Haxton M et al. · 2026 · OTJR : occupation, participation and health
Interventions to address polypharmacy and improve adherence are insufficient for community-dwelling older adults. To examine the feasibility, acceptability, and preliminary efficacy of a tailored medication management intervention (TIMM)…
View details →Negative / Null Result ReportMedicine
Koubek CT, Aghaee MA · 2026 · Journal of economic entomology
Lygus hesperus Knight (Hemiptera: Miridae) is a major pest of California strawberries, where feeding injury from nymphs and adults leads to fruit deformation and economic losses. Management relies heavily on insecticides, with supplemental…
View details →Negative / Null Result ReportMedicine
Li Z, Li X, Yang B et al. · 2026 · Frontiers in oncology
Background Multidisciplinary team (MDT) care is widely advocated for soft tissue sarcoma (STS), yet real-world evidence in high-grade disease remains limited and subject to confounding. We investigated whether pre-treatment MDT care was…
View details →Negative / Null Result ReportMedicine
Shah M, Burshtein J, Zakria D et al. · 2026 · Journal of drugs in dermatology : JDD
Background Mineral sunscreens are increasingly favorable among consumers. However, mineral sunscreens typically cause a white cast that can impact consumer selection and application. Objective This study measured the whitening effect of…
View details →Negative / Null Result ReportMedicine
Wei W, Shi Y, Hu Q · 2026 · Cirugia y cirujanos
Objectives This study aimed to evaluate and compare the effects of prolonged daily wear of a surgical mask (SM) versus a KN95 respirator on tear film stability in healthcare workers. Methods Forty-eight healthcare workers (96 eyes) were…
View details →Negative / Null Result ReportMedicine
Hamersma S, McFarlane M · 2026 · The Milbank quarterly
Policy Points Reimposing work requirements for the Supplemental Nutrition Assistance Program-by removing temporary, location-based waivers-causes a decline in food assistance participation among childless women. This loss of nutritional…
View details →Negative / Null Result ReportOpen accessMedicine
Elsamalouty I, Gupta A, Whitmore M et al. · 2026 · Cureus
Background Laparoscopic bile duct exploration (LBDE) enables single-stage management of common bile duct (CBD) stones. However, large or impacted stones often necessitate choledochotomy, which is associated with increased morbidity and…
View details →Negative / Null Result ReportMedicine
Dobrzycka M, Wołoszyn P, Prud M et al. · 2026 · Journal of clinical medicine
Background : Frailty is associated with adverse postoperative outcomes and functional decline in older adults undergoing colorectal cancer (CRC) surgery. The long-term course of frailty and functional outcomes among patients undergoing…
View details →Negative / Null Result ReportMedicine
Kalkan H, Akbaş S, Pelvan SO et al. · 2026 · Scientific reports
Biomechanical analyses identify approach velocity-particularly in the final meters-as the primary mechanical determinant of vertical displacement in pole vault; yet how this velocity changes across repeated attempts performed below…
View details →Negative / Null Result ReportMedicine
Becker ES, Lum J, Mousley J et al. · 2026 · Journal, physical therapy education
Introduction Leadership development (LD) is important in preparing leaders to successfully navigate the future of health care. Measuring the outcome of LD is vital in ensuring that LD programs effectively meet their intended learning…
View details →Negative / Null Result ReportMedicine
Ben-Ami E, Raveh E, Harpaz E et al. · 2026 · Pharmaceutical medicine
Background Eye movement biomarkers are emerging as promising tools for monitoring neurodegenerative diseases in clinical trials. Saccadic hypometria, the reduced saccade amplitude leading to undershooting visual targets, is a recognized…
View details →Negative / Null Result ReportOpen accessMedicine
Lee D, Lee GW, Yoon SH · 2026 · BMC ophthalmology
BACKGROUND: This study aimed to investigate whether the blood supply associated with the rectus muscles may influence corneal and conjunctival temperature by comparing the changes in ocular surface temperature, estimated by infrared…
View details →Negative / Null Result ReportOpen accessMedicine
Türkoğlu F, Sarı S, Gencer EN et al. · 2026 · Journal of clinical medicine
Background/Objectives : While bariatric surgery is known to improve plantar pressure distribution and reduce foot-related symptoms, its impact on radiographic forefoot alignment parameters, such as the intermetatarsal angle (IMA) and…
View details →Negative / Null Result ReportOpen accessMedicine
Stapleton JR, Heilmann NZ, Cattell K et al. · 2026 · JBMR plus
As HR-pQCT increases in popularity for studying bone dynamics, it becomes increasingly important to quantify the factors that impact rigor and reproducibility in research, particularly for longitudinal studies. Previously reported data for…
View details →Negative / Null Result ReportMedicine
Abdul-Kafi O, Chedid M, Ansani T et al. · 2026 · Cardiovascular revascularization medicine : including molecular interventions
Background Patients with severe aortic valve stenosis and concomitant mild to moderate mitral stenosis (MS) or mitral regurgitation (MR) from mitral annular calcification (MAC) often undergo aortic valve replacement (AVR) while sparing the…
View details →Negative / Null Result ReportMedicine
Morishita T, Takada D, Itoshima H et al. · 2026 · Cardiovascular intervention and therapeutics
Japan introduced nationwide physician work-hour limits in April 2024. Because cardiovascular emergencies require continuous in-hospital availability, concerns existed that restricting duty hours could reduce access to revascularization or…
View details →Negative / Null Result ReportOpen accessMedicine
Kucukosmanoglu M, Ardıc ML, Koca F et al. · 2026 · Journal of cardiovascular development and disease
Introduction: Prolongation of the QT interval and QRS duration, which are markers of ventricular repolarization and depolarization, has been reported in patients receiving flecainide therapy. However, the effects of flecainide on the QRS-T…
View details →Negative / Null Result ReportMedicine
Arfaee F, Shariati S, Armin A · 2026 · Veterinary ophthalmology
Objective Mydriatic and cycloplegic agents are widely used in veterinary ophthalmology to enable posterior segment examination. This study evaluated the effects of topical 1% cyclopentolate on intraocular pressure (IOP), horizontal pupil…
View details →Negative / Null Result ReportMedicine
Xu HJ, Liu QL, Zhang YF et al. · 2026 · International journal of molecular sciences
Dendrobium huoshanense water extract (DHWE) exhibits hypoglycemic effects in streptozotocin-induced type 1 diabetic (STZ-T1D) rats. However, its regulatory impact on the gut microbiota of T1D rats remains largely unclear. In this study,…
View details →Negative / Null Result ReportMedicine
Sayyed-Hosseinian SH, Samadi S, Yazdi P et al. · 2026 · BMC musculoskeletal disorders
Background Calcaneal fractures, the most common tarsal fractures, often result in significant long-term disability and impose substantial healthcare burdens. Surgical intervention aims to restore hindfoot anatomy, but the role of…
View details →Negative / Null Result ReportMedicine
Parikh P, Zeilani M, Pieret A et al. · 2026 · Nutrition reviews
Malaria and malnutrition adversely affect maternal and neonatal health in Sub-Saharan Africa. While intermittent preventive treatment of malaria in pregnancy (IPTp) is widely used to reduce malaria incidence, the potential additional…
View details →Negative / Null Result ReportMedicine
Eze CE, Alveo R, Barria L et al. · 2026 · Functional plant biology : FPB
Mitigating the negative impact of climate change on tropical forests requires a comprehensive understanding of the direct and indirect effects of climate variables such as temperature and vapor pressure deficit (VPD). We investigated the…
View details →Negative / Null Result ReportMedicine
Cheung J, Huang T, Tarar A et al. · 2026 · Clinical nutrition ESPEN
Background Neurocritically ill patients often face challenges in achieving adequate nutrition due to hypermetabolism and feeding difficulties, which may influence neurological recovery and overall clinical outcomes. Methods This…
View details →Negative / Null Result ReportMedicine
Emori H, Shiono Y, Yamanobe H et al. · 2026 · International journal of cardiology
Background Intravascular lithotripsy (IVL) and rotational atherectomy (RA) are established plaque-modifying strategies for heavily calcified coronary lesions. Despite their different mechanisms, the incidence of significant periprocedural…
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