Negative / Null Result ReportOpen accessMedicine
fatemeh marhemati, reza mir arab razi, mostafa azizi · 2020 · آموزش پزشکی
Background and Objective: Creating and developing self-directed learning skills has become one of the goals of education in recent decades, and today's students need to learn and acquire comprehensive information in this regard, or better to say, learn information and communication technology skills, to Be able to use electronic services. The purpose of this study was to investigate the relationship between electronic citizenship knowledge and self-directed learning of students of University of Mazandaran and Babol University of medical sciences. Methods: This study is descriptive-analytical i
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Justin Fulkerson, MSN, Robert Lowe, BSN, Tristan Anderson, BSN et al. · 2016 · Western Journal of Emergency Medicine
Introduction: This study compared the effects of vasopressin via tibial intraosseous (IO) and intravenous (IV) routes on maximum plasma concentration (Cmax), the time to maximum concentration (Tmax), return of spontaneous circulation (ROSC), and time to ROSC in a hypovolemic cardiac arrest model. Methods: This study was a randomized prospective, between-subjects experimental design. A computer program randomly assigned 28 Yorkshire swine to one of four groups: IV (n=7), IO tibia (n=7), cardiopulmonary resuscitation (CPR) + defibrillation (n=7), and a control group that received just CPR (n=7).
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Zainab Y. Ejam, Şevki Adem, Asmaa Kadhim Gatea · 2024 · Medical Journal of Babylon
Background: Vascular endothelial growth factor (VEGF) is crucial for the implantation of a fertilized egg and for the development of placental blood vessels. This study was conducted to detect the serum VEGF level of pregnant with different types of assisted reproductive techniques in relation to the age group, body mass index (BMI), and type of infertility. Objectives: The aim of this study was to determine the levels of serum VEGF in different types of assisted pregnancy. Materials and Methods: Enzyme-linked immunosorbent assay was used for the detection of VEGF levels in the serum of pregna
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Pius Pum Tseuguem, Télesphore Benoît Nguelefack, Elvine Pami Nguelefack-Mbuyo et al. · 2026 · Scientific Reports
Abstract Extracts of Paullinia pinnata have demonstrated therapeutic effects in monosodium urate (MSU)-induced gout in rats, notably by reducing inflammation and hyperalgesia, as well as enhancing antioxidant activity in vivo. However, their in vitro antioxidant potential and their effects on MSU-stimulated macrophages remain insufficiently explored. This study aims to investigate the in vitro antioxidant properties of P. pinnata, with a particular focus on MSU uptake in stimulated macrophages. The in vitro antioxidant activities of aqueous (AEPP) and methanolic (MEPP) extracts of P. pinnata l
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Yuchun Liu, Ning Wang, Changsong Jiang et al. · 2020 · Scientific Reports
Abstract Among surface irrigation systems, long border and furrow are more adaptive to mechanized farming but may cause a non-uniform distribution of water and nutrients. In this study, field experiments were carried out in a flat silage corn field in Hebei, China to investigate the uniformity along the length of border or furrow to understand the spatial and temporal distribution characteristics of soil water, electrical conductivity, and nitrate. This will guide irrigation and fertigation management recommendations, land consolidation, and high standard farmland construction. Border and furr
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Bing-Hui Li, Tong Deng, Qiao Huang et al. · 2019 · American Journal of Men's Health
The objective of this study was to evaluate association between body mass index (BMI) and prostate volume (PV), international prostate symptom scores (IPSS), maximum urinary flow rate ( Q max ), and post-void residual (PVR) of Chinese benign prostatic hyperplasia (BPH) patients. All newly diagnosed BPH patients between September 2016 and August 2018 were selected and 788 patients were included. According to BMI, the patients were categorized into four groups, while according to PV, IPSS, Q max , and PVR, they were categorized into two groups based on clinical significant cutoffs. Univariable a
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Han Yuan, Maeng-Kyu KIM · 2025 · Scientific Reports
Abstract This study investigated neuromuscular variations across low to moderate target force levels, three knee joint angles and tibial rotation positions, examining their correlations with muscle morphology and their collective impact on force steadiness (FS). Twelve young adult males performed knee extension tasks under three different tibial rotation conditions: internal rotation (IR), neutral rotation (NR), and external rotation (ER). All tasks involved submaximal isometric contractions at the knee joint. Participants performed submaximal isometric contractions at three knee joint angles
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Akihiko Kimura, Yuko Ishida, Mizuho Nosaka et al. · 2023 · Scientific Reports
Abstract Estimating time of death is one of the most important problems in forensics. Here, we evaluated the applicability, limitations and reliability of the developed biological clock-based method. We analyzed the expression of the clock genes, BMAL1 and NR1D1, in 318 dead hearts with defined time of death by real-time RT-PCR. For estimating the time of death, we chose two parameters, the NR1D1/BMAL1 ratio and BMAL1/NR1D1 ratio for morning and evening deaths, respectively. The NR1D1/BMAL1 ratio was significantly higher in morning deaths and the BMAL1/NR1D1 ratio was significantly higher in e
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Ayoola Ibifubara Aiyegbusi, Bosede Abidemi Tella, Ganiyat Adebanke Sanusi · 2020 · Nigerian Postgraduate Medical Journal
Background: Achilles tendinopathy (AT) is one of the most frequently reported ankle and foot overuse injuries. Prior studies have reported altered biomechanical variables of the lower limb as risk factors for the prevalence and severity of AT in athletes, especially in Caucasians, but there are few reports on African elite athletes. Because it is established that anthropometric and biomechanical values vary with racial disposition, this study was designed to investigate the association between selected physical and biomechanical variables of the lower limb and the prevalence and severity of AT
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Maryam Rad, Arash Shahravan, Ali Akbar Haghdoost · 2017 · Journal of Oral Health and Oral Epidemiology
BACKGROUND AND AIM: Foods containing carbohydrates have a major effect on the pathogenesis of dental caries. There is a direct correlation between frequency of consumption of foods containing sugar and dental caries. The purpose of this study was to evaluate the dietary patterns of 12-year-old children and their awareness about the effect of diet on oral health in Iran. METHODS: A cross-sectional survey was conducted on 1554 children aged 12 years in 5 provinces in Iran. Subjects were selected based on a multistage stratified cluster random sampling procedure. Data were collected by a cultural
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Amrita S Kumar, A Geetha, Jim Joe et al. · 2021 · Journal of Clinical and Diagnostic Research
Introduction: Blood donation is one of the most significant contributions that a person can make towards the society. A donor generally donates maximum 450 mL of blood at the time of donation. If 450 mL of blood is taken in a donation, men lose 242±17 mg and women lose 217±11 mg of iron. Hence, adequate iron stores are very important in maintenance of the donor’s health. Aim: To assess the influence of frequency of blood donation on iron levels of blood donors by estimating Haemoglobin (Hb) and other blood indices which reflect iron status of blood and serum ferritin which reflects body iron s
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Giuseppe Carruba, Maria Luisa Calagna, Ildegarda Campisi et al. · 2022 · Diseases
This paper presents a multi-professional integrated approach toward the recognition and management of the nutritional and psychological needs of cancer patients. In particular, the patients undertook a multi-professional, multistep process that included the collection of both personal and clinical data, the evaluation of anthropometric measures, nutritional status and psychometric indices, and an ensuing personalized nutritional prescription and psychological support, ultimately leading to combined nutritional and psychological interventions to control their adherence to a nutritional program
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Davis C Woodworth, Adelle Dagher, Adam Curatolo et al. · 2018 · PLoS ONE
The Multidisciplinary Approach to the Study of Chronic Pelvic Pain (MAPP) Research Network has yielded neuroimaging and urinary biomarker findings that highlight unique alterations in brain structure and in urinary proteins related to tissue remodeling and vascular structure in patients with Urological Chronic Pelvic Pain Syndrome (UCPPS). We hypothesized that localized changes in diffusion tensor imaging (DTI) measurements might be associated with corresponding changes in urinary protein levels in UCPPS. To test this hypothesis, we created statistical parameter maps depicting the linear corre
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Hana Wakasa, Satoshi Sunohara, Takashi Kimura et al. · 2025 · PLoS ONE
Obesity is a growing global health concern and has been associated with increased mortality from various cancer types, including hematological malignancies. However, evidence for this association in Asian populations, particularly among Japanese adults, remains limited. Thus, this study aimed to examine the association between obesity and mortality due to hematological malignancies. Data from 97,073 participants in the Japan Collaborative Cohort (JACC) Study were analyzed. The participants were followed for a mean duration of 17 years. Body mass index (BMI) was calculated using self-reported h
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Muhammad Hussain Iqbal, Tanveer Hussain, Fariha Khalid et al. · 2020 · Pakistan Armed Forces Medical Journal
Objective: To determine the frequency of diastasis recti abdominis and its associated risk factors in postpartum women. Study Design: Cross-sectional study. Place and Duration of Study: Omar Medical Center Lahore, Yaseen Medical Center Lahore and Social Security Hospital Lahore, from Sep 2019 to Dec 2019. Methodology: This study included 128 participants fulfilling the eligibility criteria. The assessment of diastasis recti abdominis was done manually by a female physiotherapist using single finger, double finger and three finger methods on abdomen at three levels: at the umbilicus, 4.5 cm bel
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Tao Li, Xiaodong Zhou, Zhi Wang et al. · 2016 · PLoS ONE
To evaluate retinal thickness (RT), retinal volume (RV) and choroidal thickness (ChT) in Chinese children using Cirrus-HD optical coherence tomography (OCT), and assess their associations with spherical equivalent (SE), age and gender.This was a prospective study that recruited 193 healthy Chinese children (193 eyes) with no ophthalmic disease history between December 2012 and December 2013. RT and RV were acquired using OCT. Subfoveal ChT (SFCT) and ChT1-mm and 2-mm temporal, nasal, superior and inferior to the fovea were measured manually.RT in the inner temporal and nasal regionsdiffered si
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Shanshan Shi, Xiuchun Zhang, M Alejandra Mandel et al. · 2017 · PLoS ONE
Cassava (Manihot esculenta) is an important tropical subsistence crop that is severely affected by cassava brown streak disease (CBSD) in East Africa. The disease is caused by Cassava brown streak virus (CBSV) and Ugandan cassava brown streak virus (UCBSV). Both have a (+)-sense single-stranded RNA genome with a 5' covalently-linked viral protein, which functionally resembles the cap structure of mRNA, binds to eukaryotic translation initiation factor 4E (eIF4E) or its analogues, and then enable the translation of viral genomic RNA in host cells. To characterize cassava eIF4Es and their potent
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Linh Tran, Jeah Jung, Roger Feldman et al. · 2022 · PLoS ONE
Purpose Chronic hepatitis C virus (HCV) infection is an important public health concern. Limited information exists on disparities in the quality of HCV care. We examine disparities in genotype or quantitative HCV ribonucleic acid testing before and after starting HCV treatment, and screening for hepatocellular carcinoma (HCC) in HCV patients with cirrhosis. Methods This national study included Medicare beneficiaries with HCV between 2014 and 2017. We used bivariate probit to estimate the probability of receiving recommended tests before and after HCV treatment by patient race/ethnicity, urban
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F. E. Kocak, M. Yöntem, Ö. Yücel et al. · 2013 · Biochemia Medica
Introduction: Today, the pneumatic tube transport system (PTS) is used frequently because of its advantages related to timing and speed. However, the impact of various types of PTS on blood components is unknown. The aim of this study was…
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Sigrid Børte, Bendik S Winsvold, Synne Øien Stensland et al. · 2017 · PLoS ONE
Background There is little knowledge about how factors early in life affect the development of migraine and tension-type headache. We aimed to examine whether growth restriction in utero is associated with development of migraine and frequent tension-type headache in adults. Methods The population-based Nord-Trøndelag Health Study (HUNT 3) contained a validated headache questionnaire, which differentiated between migraine and tension-type headache. These data were linked to information on weight and gestational age at birth from the Norwegian Medical Birth Registry. In total 4557 females and 2
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Rob Janssen, Jef Serré, Ianthe Piscaer et al. · 2020 · ERJ Open Research
Background Vitamin D supplementation lowers exacerbation frequency in severe vitamin D-deficient patients with COPD. Data regarding the effect of vitamin D on elastin degradation are lacking. Based on the vitamin's anti-inflammatory properties, we hypothesised that vitamin D supplementation reduces elastin degradation, particularly in vitamin D-deficient COPD patients. We assessed the effect of vitamin D status and supplementation on elastin degradation by measuring plasma desmosine, a biomarker of elastin degradation. Methods Desmosine was measured every 4 months in plasma of 142 vitamin D-na
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Luis M. Pérez-Belmonte, José David Torres-Peña, María D. López-Carmona et al. · 2020 · BMC Medicine
Abstract Background Limited evidence exists on the role of glucose-lowering drugs in patients with COVID-19. Our main objective was to examine the association between in-hospital death and each routine at-home glucose-lowering drug both individually and in combination with metformin in patients with type 2 diabetes mellitus admitted for COVID-19. We also evaluated their association with the composite outcome of the need for ICU admission, invasive and non-invasive mechanical ventilation, or in-hospital death as well as on the development of in-hospital complications and a long-time hospital st
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Xin Zhao, Chaoxuan Wang, Jian Wang et al. · 2026 · Scientific Reports
Abstract Sarcopenia, the progressive loss of muscle mass and function, is a significant health concern in middle-aged and older adults, potentially linked to adverse outcomes like falls and fractures. A cohort study was conducted utilizing participants aged ≥ 45 years from CHARLS. Sarcopenia was defined using established criteria. Primary outcomes were isolated falls, isolated hip fractures, and composite outcomes. Associations were assessed using multivariable Cox regression (adjusted for confounders), propensity score matching (PSM), and inverse probability weighting (IPW), reporting hazard
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H. Henjum, Karoline Mo Feten, Erlend Hartvigsen et al. · 2025 · Acta oncologica
Background and purpose Proton Arc Therapy (PAT) is an emerging proton therapy treatment modality with the potential to reduce radiation exposure to healthy tissues compared to conventional Intensity-Modulated Proton Therapy (IMPT) with…
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Artha Falentin Putri Susilo, Hanom Husni Syam, Hartanto Bayuaji et al. · 2024 · Scientific Reports
Abstract Vitamin D and calcium in follicular fluid play an important role in modulating steroidogenesis, folliculogenesis, and oocyte quality determination. Both collaborate to produce top-quality embryos (TQE) during in vitro fertilization (IVF). In this study, we compared free 25(OH)D3 and calcium levels in follicular fluid between TQE and non-TQE groups. This cross-sectional study included women who underwent IVF procedures at tertiary hospitals in Bandung, Indonesia. Ovarian follicular fluid was collected during the ovum pick-up procedure. The examination of 25(OH)D3 levels, vitamin d-bind
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Sarah Moreira de Sousa Gomes, Paulo César Apolinário de Souza, Cassiane Freitas Rodrigues et al. · 2026 · DST
Introduction: Women living with HIV/AIDS (WLHA) are more vulnerable to human papillomavirus (HPV) infection, particularly by high-risk oncogenic subtypes, due to HIV-associated immunosuppression. Objective: To assess the prevalence and distribution profile of HPV subtypes in WLHA, correlating findings with CD4 levels and age group. Methods: A cross-sectional study was conducted with 184 WLHA receiving care at a public referral center in Juiz de Fora, Minas Gerais, from May 2021 to May 2022. Self-collected vaginal samples were analyzed by RT-PCR to detect HPV subtypes. Associations between HPV
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Gieira S Jones, Heather Spencer Feigelson, Roni T Falk et al. · 2019 · PLoS ONE
Background Breast density, as estimated by mammography, is a strong risk factor for breast cancer in pre- and postmenopausal women, but the determinants of breast density have not yet been established. The aim of this study was to assess if urinary estrogens or gut microbiota alterations are associated with mammographic density in postmenopausal women. Methods Among 54 cancer-free, postmenopausal controls in the Breast and Colon Health study, we classified low- versus high-density women with Breast Imaging Reporting and Data System (BI-RADS, 5th edition) mammographic screening data, then asses
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Memota Laishram, Krishnagopal Srikanth, AR Rajalakshmi et al. · 2017 · Journal of Clinical and Diagnostic Research
Introduction: Macular disease is the leading cause of low vision in the Western world. Drusen and pigmentary irregularities are common among the rural Northern Indian population. The disease process leads to loss of central vision, metamorphopsia, macropsia or micropsia and colour vision defect. Aim: To study the retinal sensitivity changes in macular diseases using microperimetry. Materials and Methods: It was an observational study, conducted in the Department of Ophthalmology at a rural tertiary care hospital. This study was started from December 2014 until June 2016, in all patients with m
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Tiara Sekar Ayudhipasha, Menik Herdwiyanti, Sedayu Sedayu · 2025 · GHMJ (Global Health Management Journal)
Background: West Java ranks the highest Province with Human Immunodeficiency Virus (HIV) case in 2023. An estimated 1.648 patients estimated receive antiretroviral therapy (ART). Kidney disease contributes mortality amongst people living with HIV/AIDS (PLWH). Tenofovir disoproxil fumarate (TDF)-based ART was associated as risk factor of kidney disorders, indicate by declining glomerular filtration rate (GFR). However, there is limited study whether kidney disease among PLWH were related to ART use in Indonesia. Aims: To determine correlation between duration of antiretroviral therapy and glome
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Derya Koyun, Gokhan Nergizoglu, Kemal Metin Kir · 2018 · Saudi Journal of Kidney Diseases and Transplantation
The loss of muscle mass and cachexia is commonly seen in hemodialysis (HD) patients and contribute to morbidity and mortality. The exact mechanism of this fact is multifactorial and still unclear. Myostatin, a transforming growth factor-ß family ligand, is released from the skeletal and heart muscle and may be responsible for muscle degradation and atrophy. The aim of this study is evaluation of the relationship between muscle mass and serum myostatin level in chronic HD patients. One hundred and forty HD patients (79 males, 28 diabetic, mean age; 53.96 ± 13.6) were included in this cross-sect
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