12,244 real negative results, null findings, and replication failures in Medicine. Search the index →
WASTE indexes published research — it does not host or republish full papers. Each entry is a metadata record compiled from open scholarly databases; the abstract is shown in full only where the paper is openly licensed, otherwise a short excerpt under fair use. Classifications are automated and approximate.
Arije D, Bista P, Gautam S et al. · 2026 · Field Crops Research.
Cultivated soils in arid and semi-arid regions are vulnerable to soil organic carbon (SOC) loss due to variable crop yields, residue removal, and frequent fallowing. Replacing fallow periods with cover crops has been promoted to increase…
View details →Yi Y, Yano K · 2025 · Physiologia plantarum
Elevated CO 2 (eCO 2 ) can enhance plant growth, but it may also accelerate senescence, which could offset the growth benefits. Phosphorus (P) supply can enhance the photosynthetic rate under eCO 2 conditions and promote biomass…
View details →Gupta N, Seo J, Phan F et al. · 2026 · Heart rhythm
Background Lead dwell time (DT) is associated with increased complexity of cardiac implantable electronic device (CIED) extraction. Optimal strategies for risk mitigation are not well studied. Objective This study aimed to evaluate the…
View details →Chen YF, Kou HW, Chen TH et al. · 2026 · Journal of gastrointestinal cancer
Purpose Radical surgery is the primary treatment for localized gastric cancer (GC), but the benefit of adjuvant chemotherapy in stage IB GC remains unclear. This study evaluates its impact on recurrence and survival post-gastrectomy.…
View details →Andrade A, Mureb M, Karaman N et al. · 2026 · Journal of neuro-oncology
PURPOSE: KRAS G12C mutations occur in approximately 11% of non-small-cell lung cancer (NSCLC) patients and are associated with aggressive disease and poor prognosis. Although KRAS G12C-inhibitors are now approved, their impact on Gamma…
View details →Mikami R, Imai S, Hayakawa M et al. · 2025 · Die Pharmazie
This study aimed to evaluate the temporal effect of a serum creatinine (SCr) correction intervention in critically ill patients with daily muscle wasting. A total of 5,355 critical care days in 574 patients with creatinine clearance (Clcr)…
View details →Montenegro J, Oliveira CL, Nguyen NK et al. · 2026 · The Journal of nutrition
Background Excess body weight is associated with chronic low-grade inflammation and metabolic abnormalities, such as insulin resistance, and dyslipidemia. Objectives This study aimed to assess the impact of a soy protein-yogurt-honey…
View details →Bliesner RK, Stevens AA, Holling L et al. · 2026 · Cureus
Background Being in the large majority, right-handed people are not required to use their nondominant hands throughout their daily lives, resulting in a loss of motor dexterity. As technology continues to advance, improving motor dexterity…
View details →Nascimento GO, Otávio KS, Ferreira J et al. · 2026 · Tropical animal health and production
Bioactive peptides (BP) have been investigated as potential functional feed additives due to their reported immunomodulatory and metabolic properties. This study evaluated the effects of dietary BP supplementation on growth performance,…
View details →Tortajada M, Rodríguez-Larios J, Martínez-Pérez V et al. · 2026 · Journal of cognitive neuroscience
Recent findings have shown the influential role of theta-gamma cross-frequency coupling in the maintenance of items in working memory (WM). Specifically, it has been proposed that individual items are represented within gamma oscillations…
View details →Kim SB, Lopez A, Gu X et al. · 2026 · Journal of vitreoretinal diseases
Purpose: To evaluate real-world differences in treatment frequency, appointment compliance, and visual outcomes among patients with DME or RVO whose eyes either remained on antivascular endothelial growth factor (anti-VEGF) therapy or were…
View details →Sobel Misieczko M, Barber SJ · 2026 · Neuropsychology, development, and cognition. Section B, Aging, neuropsychology and cognition
Affective forecasting, the process of predicting future feelings, is key for decision-making, but prone to errors. Prior research suggests that age differences in forecasting accuracy vary by event valence such that older adults tend to be…
View details →Alberts KO, Espiritu IJ, Castel AD · 2026 · Experimental aging research
Background Young and older adults are often victimized by various forms of scams and fraud. However, little research has been conducted on how a scam prevention intervention may impact young and older adults' accuracy and confidence in…
View details →Brisola GMP, da Cruz AL, Belorio LGDS et al. · 2026 · Journal of strength and conditioning research
Abstract Brisola, GMP, da Cruz, AL, Belorio, LGdS, Grossi, JP, De Poli, RAB, Zagatto, AM, Esco, MR, and Mendes, OdC. Effects of dry-land versus in-water resistance priming exercise on performance parameters of young female water polo…
View details →Arraes Rocha Felix V, Rohani P, Drake JM · 2026 · Journal of the Royal Society, Interface
Infectious disease forecasting is important to public health decision-making, particularly for mitigating the burden of seasonal influenza. We propose and evaluate comprehensive autoregressive modelling approaches (autoregressive…
View details →Hill CR, Balmer L, Abbiss H et al. · 2026 · Food & function
S -Methyl cysteine sulfoxide (SMCSO) is an organosulfur compound with demonstrated hypocholesterolemic, anti-diabetic, and antioxidant benefits in rodents. However, the doses used have limited translatability for humans. We explored…
View details →Vargas Ribera PR, Nogales A, Calvet C et al. · 2026 · Applied Soil Ecology.
Crop rotation enhances agroecosystem sustainability by reducing nutrient loss, improving soil fertility, and decreasing crop evapotranspiration. Arbuscular mycorrhizal fungi (AMF) inoculation further supports enhanced nutrient and water…
View details →Di Cesare B, Mancini GF, Parente M et al. · 2026 · Life sciences
Aims Metabolic syndrome (MetS) is characterized by several metabolic alterations that may increase the risk of memory alterations. While metabolic consequences of MetS are well documented, its memory impact remains underexplored. This…
View details →Leal RMS, Campos MCBP, Copelli FA et al. · 2026 · International endodontic journal
Aim To evaluate the endodontic retreatment of S-shaped mesial root canals of mandibular molars using the Reciproc Blue R25 and R40 instruments, with or without the use of an orange oil solvent, and to assess the effect of additional apical…
View details →Ko E, Kim YH, Lee S et al. · 2025 · The Journal of surgical research
Introduction Sepsis is a severe pathological crisis marked by infection and systemic inflammation with high mortality rates. Sepsis induces microcirculatory dysfunction and oxidative stress, which share pathophysiological features with…
View details →Dong Z, Wu L, Du H et al. · 2026 · Gastroenterology
Background & aims Evidence about the effect of artificial intelligence (AI) on upper endoscopy in multicenter, randomized controlled trials is lacking. We aimed to explore whether AI can enhance gastric neoplasm detection. Methods…
View details →Greistofer E, Taher F, Assadian A et al. · 2026 · Annals of vascular surgery
Background The objective of this study was to evaluate the prognostic value of routine postoperative laboratory parameters including renal function, inflammatory markers, and hematologic indices in patients undergoing fenestrated…
View details →Lee TY, Hunter DA, Perez R et al. · 2026 · The Journal of hand surgery
Purpose Polyethylene glycol (PEG) fusion has been reported to restore axonal continuity after nerve repair if initiated before Wallerian degeneration (WD). Sterile α and Toll/Interleukin-1 Receptor motif-containing 1 (SARM1) inhibition can…
View details →Umbricht D, Abt M, Derks M et al. · 2026 · The Journal of clinical psychiatry
Objective: Cognitive impairment associated with schizophrenia (CIAS) is a key driver of functional deficits in patients with this disorder. CIAS may involve deficient NMDA receptor-dependent neurotransmission. Negative allosteric…
View details →Kitowski A, Heise C, Sperling S et al. · 2026 · British journal of pharmacology
Background and purpose Nano-formulated chemotherapeutics prolong systemic availability of drugs and can reduce systemic toxicity, but their accumulation in solid tumours is often limited and unpredictable. Broadly applicable strategies to…
View details →Talathi R, Hubbard RA, Somasundar P et al. · 2026 · Surgery
Background The Surgery With or Without Neoadjuvant Chemotherapy in High Risk RetroPeritoneal Sarcoma (STRASS 2) trial is evaluating the impact of neoadjuvant chemotherapy versus surgery in patients with high-risk, resectable…
View details →Zhao A, Chen W, Liang Y et al. · 2026 · Cancer treatment and research communications
Objective To compare and analyze the efficacy and safety of an overall strategy of immunotherapy combined with chemoradiotherapy in patients with limited-stage small cell lung cancer (LS-SCLC)-including induction immunotherapy plus…
View details →Sarica C, Darmani G, Ramezanpour H et al. · 2026 · Science translational medicine
Transcranial ultrasound stimulation (TUS) is a promising noninvasive technique for modulating deep brain targets and circuits with high spatial precision. For its successful clinical translation, confirmation of target engagement, together…
View details →Riestra JM, Levin-Carrion Y, Sutar R et al. · 2026 · Human psychopharmacology
Treatment-resistant depression (TRD) remains a formidable challenge in psychiatry, with nearly one-third of patients with major depressive disorder (MDD) failing to respond adequately to first-line pharmacological treatments.…
View details →Nandi D, Gajarski RJ, Zhao H et al. · 2026 · Pediatric transplantation
Purpose Human Leukocyte Antigen (HLA) sensitization can adversely impact heart transplant (HTx) outcomes. We evaluated the effect of panel-reactive antibody (PRA) and desensitization (DS) strategies on outcomes of pediatric HTx recipients…
View details →