12,375 real negative results, null findings, and replication failures in Medicine. Search the index →
WASTE indexes published research — it does not host or republish full papers. Each entry is a metadata record compiled from open scholarly databases; the abstract is shown in full only where the paper is openly licensed, otherwise a short excerpt under fair use. Classifications are automated and approximate.
Nageswaran S, Easterling D, Skaar JE et al. · 2025 · Pediatrics
Background and objectives Improving home health (HH) care for children with medical complexity (CMC) is critical. We developed ICollab, a care model involving collaboration between a children's hospital's complex care clinicians, HH…
View details →Nahmias J, Stopenski S, Jebbia M et al. · 2025 · JAMA surgery
Importance Traumatic rib fractures are associated with significant morbidity, including pulmonary complications and prolonged opioid use. Identifying adjunctive treatments that can reduce opioid consumption without compromising safety…
View details →Cariou B, Thys A, Oliveira AR et al. · 2025 · Diabetes, obesity & metabolism
Aims Postprandial hyperlipidaemia (PPL), characterized by elevated triglyceride (TG) concentrations after a meal, is common in type 2 diabetes (T2D) and is often recognized as an independent cardiovascular risk factor. Here, we aimed to…
View details →Wynberg E, Mishra A, Liverani M et al. · 2026 · International journal of infectious diseases : IJID : official publication of the International Society for Infectious Diseases
Objectives Poorly targeted antibiotic use in primary care is a driver of antimicrobial resistance. Electronic clinical decision support algorithms (eCDSAs) integrating point-of-care tests may improve prescribing. We evaluated the impact of…
View details →Larsen M, Underdal M, Salvesen Ø et al. · 2025 · Sexual & reproductive healthcare : official journal of the Swedish Association of Midwives
Objective Long latent phase of labor with subsequent prolonged total labor duration increases the risk of obstetric interventions and complications. We explored whether Proactive Support of Labor (PSL) compared to Standard Support of Labor…
View details →Fujii T, Kitadani Y, Tanaka A et al. · 2025 · Journal of pediatric surgery
Background The effectiveness of prophylactic antibiotics in pediatric inguinal hernia repair remains unclear. As the procedure is considered clean, the necessity of prophylactic antibiotics is debated. Methods We conducted a retrospective…
View details →de Souza Freire T, Kawakami MD, de Almeida MF et al. · 2026 · Jornal de pediatria
Objective To determine whether the use of an electrocardiogram monitor in newborns receiving positive pressure ventilation (PPV) at birth affects the frequency of tracheal intubation in the delivery room. Methods Retrospective cohort of…
View details →Veale JP, Shawdon A, D'Alessandro P et al. · 2025 · Sports (Basel, Switzerland)
A history of anterior cruciate ligament reconstruction (ACLR) during the Australian Football (AF) talent pathway may impact draft prospects and increase the risk of a second injury during a professional career. This study investigated…
View details →Meer R, Xu JY, Newsom SP et al. · 2026 · The American journal of clinical nutrition
Background Medial arterial calcification (MAC) and increased arterial stiffness contribute to cardiovascular disease risk in type 2 diabetes mellitus (T2DM). Experimental studies suggest that magnesium supplementation may halt arterial…
View details →Sigera C, Oliveira CB, Melman A et al. · 2026 · NPJ digital medicine
This study evaluated the effectiveness of a virtual hospital model of care (Back@Home) for low back pain (LBP). We conducted an observational study across four hospitals in the Sydney Local Health District, Australia. We included patients…
View details →Ozden Yuce M, Simsek B, Dadas OF et al. · 2026 · Journal of oral and maxillofacial surgery : official journal of the American Association of Oral and Maxillofacial Surgeons
Background Preoperative anxiety in patients undergoing third molar extraction can influence pain perception. Limited evidence suggests Reiki therapy may help manage anxiety and pain, but its effectiveness in dentistry is unclear. Purpose…
View details →Seefeldt CS, Knievel J, Deeb M et al. · 2025 · JAMA surgery
Importance Chronic postoperative pain and recurrence are relevant complications after inguinal hernia repair. Biological meshes have been proposed as a resorbable alternative to synthetic implants that may reduce postoperative pain.…
View details →Bonasia K, Luong S, Stairs J et al. · 2026 · International urogynecology journal
Introduction and hypothesis Obstetric anal sphincter injuries (OASIs) are associated with increased risk of postpartum complications, including short- and long-term dyspareunia and sexual dysfunction. The primary aim of this analysis is to…
View details →Wang Y, Jia Z, Jiao J et al. · 2025 · Gynecologic oncology
Objective To assess the use of prophylactic ureteral stent for preventing ureteral injury in patients with cervical cancer undergoing radical hysterectomy. Methods This retrospective study included 304 patients with cervical cancer who…
View details →Li YC, Wang JY, Lei MJ et al. · 2026 · Health science reports
Background and aims To inquire the effect of extending the duration of dual antiplatelet therapy (DAPT) to 18-24 months on the prognosis of patients with ST segment elevation myocardial infarction (STEMI) undergoing percutaneous coronary…
View details →Idoudi S, Hassan AF, Kheraldine H et al. · 2026 · Scientific reports
Ketamine (KET) exhibits potential anticancer activity, with enhanced cytotoxicity against melanoma cells when combined with the permeation enhancer dodecyl maltoside (DDM). To support clinical translation, this study evaluated the…
View details →Griffin AJ, Jungers JM · 2025 · Field Crops Research.
Intermediate wheatgrass (Thinopyrum intermedium; IWG) is a perennial, cool-season grass undergoing domestication as a grain and forage crop. Intercropping perennial legumes with IWG could reduce synthetic N fertilizer inputs, improve…
View details →Moraes LGDS, Oliveira VC, Macedo AP et al. · 2025 · The International journal of prosthodontics
Purpose To evaluate the antibiofilm action of 2.5 mg/mL peracetic acid (PA), 0.5 mg/mL cetylpyridinium chloride (CPC), and 160 mg/mL N-acetylcysteine (NAC) against multispecies biofilm of Streptococcus mutans, Staphylococcus aureus,…
View details →Bouman Z, De Vries F, De Ruiter M et al. · 2026 · Endoscopy international open
Background and study aims Esophagogastroduodenoscopy is a widely used medical examination. Despite the short duration of this procedure, many patients experience anxiety, pain, and discomfort. The aim of this study was to examine effects…
View details →García-García M, Mosqueda J, Escobar-Cabrera JE et al. · 2025 · Toxicon : official journal of the International Society on Toxinology
A recent clinical case involving a Poecilotheria regalis bite was treated with Mexican L. mactans antivenom (Aracmyn Plus, Silanes, Mexico), resulting in the improvement of some of the symptoms. This could be attributed to cross-reactivity…
View details →Baumann AN, Chatzis K, Son E et al. · 2026 · Spine
Study design Retrospective single-center study. Objective We aim to compare the prognostic capacity of postoperative T4-L1PA mismatch versus T4PA and L1PA alone. Summary of background data The assessment of T4-L1PA mismatch, the difference…
View details →Li YH, Cheng YC, Chang CY et al. · 2026 · Diagnostics (Basel, Switzerland)
Objectives: Multimodal large language models (MLLMs) have shown potential for medical image classification. We evaluated four optimization strategies in two MLLMs-GPT-4o (gpt-4o-2024-08-06) and Gemini 2.5 Flash-Lite-for ultrasound-based…
View details →Klaps S, Verbrugghe J, Goossens N et al. · 2026 · BMC sports science, medicine & rehabilitation
Background To compare the effects of a multimodal whole-body high-intensity training (HIT) program versus a moderate-intensity training (MIT) program on inspiratory muscle function in persons with chronic nonspecific low back pain…
View details →Biccirè FG, Arbustini E, Ozaki Y et al. · 2026 · Atherosclerosis
Background and aims Atherosclerotic plaque rupture is largely acknowledged as the main mechanism of acute coronary syndrome. However, the prognostic significance of plaque rupture detected in nonculprit coronary sites remains largely…
View details →Wisetmongkolchai T, Somboonchai P, Piromlertamorn W et al. · 2026 · JBRA assisted reproduction
Objective To investigate the effects of quercetin supplementation in aging mice on the oocyte number and in vitro fertilization outcomes. Methods Thirty-two to forty-week-old aging female mice were randomly assigned into two groups, with…
View details →Virhammar J, Fasth O, Ekblom M et al. · 2026 · The Lancet. Neurology
Background Idiopathic normal pressure hydrocephalus is a potentially reversible cause of gait disturbance, cognitive impairment, and urinary incontinence, typically in adults aged 60 years or older. Ventriculoperitoneal shunt surgery…
View details →Vasileiou D, Tsironi K, Konstantonis D et al. · 2026 · European journal of orthodontics
Objectives To evaluate the validity of digital manual and automated structural superimposition on the anterior cranial base using Björk's two-dimensional (2D) cephalometric method. Secondary aims included assessing repeatability and…
View details →Gilbert DL, Aschbacher-Smith LE, Migneault KY et al. · 2026 · Pediatric neurology
Background Children and youth with neurofibromatosis type 1 (NF1) commonly experience motor, behavioral, and cognitive problems. Promising findings from an NF1 mouse model suggested that the antioxidant N-acetylcysteine (NAC) might address…
View details →Fellers C, Storm BC · 2026 · Journal of experimental psychology. Learning, memory, and cognition
Across two experiments, we investigated the effects of cognitive offloading on prospective memory (PM). Participants performed two PM tasks, either relying on internal memory for both (Dual PM condition) or using an external reminder for…
View details →Benomar A, Fahed R, Omar AT et al. · 2026 · Journal of neurointerventional surgery
Background The Alberta Stroke Program Early CT Score (ASPECTS) and CT angiography (CTA) Collateral Score (CS) are routinely used to estimate ischemic core burden and collateral status in acute ischemic stroke due to large vessel occlusion,…
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