12,241 real negative results, null findings, and replication failures in Medicine. Search the index →
WASTE indexes published research — it does not host or republish full papers. Each entry is a metadata record compiled from open scholarly databases; the abstract is shown in full only where the paper is openly licensed, otherwise a short excerpt under fair use. Classifications are automated and approximate.
Alghizzi TM, Alshahrani TM · 2024 · Heliyon
Despite considerable evidence that supports the use of grading rubrics (GRs) as tools for written corrective feedback, there is a paucity of research that investigates which of the different types of GRs best develops learners'…
View details →Bousamaki J, Maciag G, Petersen AG et al. · 2026 · Basic & clinical pharmacology & toxicology
Nintedanib, a multitargeted tyrosine kinase inhibitor, is approved for idiopathic pulmonary fibrosis (IPF) for its ability to slow lung function decline. This study systematically evaluated the effects of nintedanib across three…
View details →Güngör HS, Łabuz G, Yildirim TM et al. · 2024 · Journal of refractive surgery (Thorofare, N.J. : 1995)
Purpose To investigate how varying levels of longitudinal chromatic aberration (LCA) affect visual quality in patients with trifocal intraocular lenses (IOLs). Methods Twenty-nine patients implanted with trifocal IOLs were assessed for…
View details →Hui Q, Xiang T, Qinglan X et al. · 2026 · Food science & nutrition
The link between Vitamin D (Vit D) deficiency and sudden sensorineural hearing loss (SSNHL), especially regarding recurrence and age-related disparities, remains unclear. Recurrence and age-specific risks of SSNHL are under addressed,…
View details →Tanabe S, Shi Y · 2024 · The American journal of case reports
BACKGROUND Retained products of conception (RPOC) is a rare complication following second-trimester delivery or pregnancy termination, often leading to significant hemorrhage. Diagnosed via ultrasound or CT, RPOC requires surgical…
View details →Hyun J, Cerino ES, Katz MJ et al. · 2025 · The journals of gerontology. Series B, Psychological sciences and social sciences
Objectives Investigating social determinants of health and related outcomes may help identify effective and sustainable intervention targets. This study examined whether contextual-level social capital (bonding and bridging capital) and…
View details →Kumekawa T, Akaihata H, Natsuya H et al. · 2024 · IJU case reports
Introduction Human T-cell lymphotropic virus type 1 infection can cause HTLV-1-associated myelopathy/tropical spastic paraparesis, characterized by spastic paralysis of both lower limbs. More than 90% of HAM/TSP patients show lower urinary…
View details →Nikolaeva A, Vandeputte M · 2025 · Endocrinology, diabetes & metabolism case reports
Summary Semaglutide, a GLP-1 receptor agonist (RA), is approved for the treatment of type 2 diabetes and obesity. However, its increasing off-label use, particularly for cosmetic weight loss, raises concerns considering its potential…
View details →El Idrissi Y, El Moudden H, Belhoussaine O et al. · 2025 · Chemistry & biodiversity
This study investigates for the first time the effects of UV light exposure on the chemical composition of artisanal and cold-pressed culinary and cosmetic argan oils, as well as their quality and biological activities. We ascertained the…
View details →Jhaj J, Woolner B, Rankin S et al. · 2025 · Shoulder & elbow
This study evaluated the outcome and recurrence rates after hydrodilatation (HD) in patients with frozen shoulder (FS), comparing the effects of injecting 25 mL or more of fluid versus lower volumes. A total of 132 shoulders (130 patients)…
View details →Banerjee S, Berry Y, Fisher E et al. · 2025 · Neuroscience letters
Genetic leukoencephalopathy (gLE) is a white matter disorder affecting the central nervous system, causing hypomyelination, developmental delays, motor deterioration, and cognitive, visual, and hearing impairments. Its clinical variability…
View details →Alsheekh A, Kibrik P, Marks N et al. · 2025 · Vascular
BackgroundThe minimally invasive procedures of venous ablation and iliac vein stenting are evolving treatment options for venous insufficiency. Yet, there are no studies directly comparing the outcome of these procedures. We performed a…
View details →Altamirano F, Gonzalez E, Oke I · 2024 · Digital journal of ophthalmology : DJO
A healthy 4-year-old boy referred for evaluation of an abnormal red reflex in the left eye was noted, on fundus examination, to have extensive white, striated lesions surrounding the optic nerve that involved the superior and inferior…
View details →Hata Y, Iida O, Torii S et al. · 2026 · European heart journal. Case reports
Background The long-term vascular response to paclitaxel-eluting stents (PESs) in infrapopliteal (IP) lesions remains histologically uncharacterized. Case summary A 78-year-old woman with chronic limb-threatening ischaemia underwent…
View details →Agergaard J, Gunst JD, Schiøttz-Christensen B et al. · 2023 · International journal of infectious diseases : IJID : official publication of the International Society for Infectious Diseases
Objectives Knowledge is limited on how changing SARS-CoV-2 variants may translate into different characteristics and affect the prognosis of patients with long COVID, especially following Omicron variants. We compared long-term prognosis…
View details →Pyzer AR, Dillon LW, Sharon E et al. · 2025 · Blood advances
Abstract We conducted a multicenter, open-label, randomized phase 2 study to assess the efficacy of nivolumab (Nivo) as maintenance therapy for patients with acute myeloid leukemia (AML) in first complete remission (CR) or CR with…
View details →Markou M, Katsouda A, Papaioannou V et al. · 2024 · Phytotherapy research : PTR
Obesity is a major source of morbidity worldwide with more than 2 billion adults being overweight or obese. The incidence of obesity has tripled in the last 50 years, leading to an increased risk for a variety of noncommunicable diseases.…
View details →Carroll AM, Pruitt DT, Riley JR et al. · 2024 · Scientific reports
Learning new skills requires neuroplasticity. Vagus nerve stimulation (VNS) during sensory and motor events can increase neuroplasticity in networks related to these events and might therefore serve to facilitate learning on sensory and…
View details →Langley C, Plakotaris E, Rogers NE · 2025 · Case reports in dermatology
Introduction Lichen planopilaris (LPP) is a well-known cicatricial alopecia with a frontal fibrosing variant. LPP has a prevalence rate of 13.4 per 100,000 persons. It is understood that LPP favors the female populations. What is not…
View details →Panca M, Serfaty M, Satchell J et al. · 2026 · BJPsych open
Background Crime has significant impact on older victims. High rates of anxiety and depression may be associated with crimes. Aims This paper aims to evaluate the cost-effectiveness of a victim improvement package (VIP) for the reduction…
View details →Fernandes Cabral DT, Fernández-de Thomas RJ, Alattar A et al. · 2024 · Neurosurgical focus: Video
Odontoid pannus is an abnormal collection of degenerative or inflammatory tissue on the C1-dens joint that can result in severe spinal cord compression myelopathy. Treatment options vary depending on severity and etiology. In cases of…
View details →Story BD, Thomasy SM, Randolph MW et al. · 2024 · Frontiers in veterinary science
Sjogren's disease, well-described in people, is rarely identified in veterinary species. In people, Sjogren's disease is one of the most common systemic autoimmune disorders with an incidence of 0.5% in the female population. The hallmark…
View details →Sood M, Hegde V, Prabhu N et al. · 2026 · Journal of Indian Prosthodontic Society
Aim This study aimed to assess the shear bond strength between three-dimensional (3D)-printed acrylic denture base resin and 3D-printed teeth with and without ridge lap surface modifications. Materials and methods The investigation…
View details →Bhatia A, Chen Z, Zhang Y et al. · 2026 · Cancer
Background Ataxia telangiectasia Rad3-related (ATR) protein kinase regulates DNA damage response and is essential for tumor cell survival. Preclinically, ATR inhibition can sensitize tumor cells to radiation and chemotherapy. The authors…
View details →Gass R, Plachi F, Silva FOB et al. · 2025 · Respiratory physiology & neurobiology
Excess exercise ventilation (high ventilation (V̇ E )/carbon dioxide output (V̇CO 2 )) contributes significantly to dyspnea and exercise intolerance since the earlier stages of chronic obstructive pulmonary disease (COPD). A selective…
View details →Karajannis MA, Onar-Thomas A, Lin T et al. · 2025 · Neuro-oncology
Background The outcome for pediatric patients with high-grade glioma (HGG) remains poor. Veliparib, a potent oral poly(adenosine diphosphate-ribose) polymerase (PARP) 1/2 inhibitor, enhances the activity of radiotherapy and DNA-damaging…
View details →Pickard S, Speach D, Hauber K et al. · 2026 · Interventional pain medicine
Background Low back injury is one of the leading causes of work-related injuries, disability, and lost productivity. Patients with lumbar radiculopathy are a subgroup of patients within work related low back injury. To our knowledge, there…
View details →Luo JY, Xiang J, Hong XL et al. · 2026 · The American journal of case reports
BACKGROUND Epidermal growth factor receptor (EGFR) is a key driver gene in non-small-cell lung cancer (NSCLC), and EGFR tyrosine kinase inhibitors (TKIs) are the standard treatment for classical mutations, including exon 19 deletion and…
View details →Raj AK, Pedersen SJ, Mainsbridge C et al. · 2024 · Ergonomics
Prolonged sitting is postulated to influence musculoskeletal performance (cervical flexor endurance, balance, and agility), discomfort and alter cervical spine angles during work-based computer use. Stair climbing breaks may be a great…
View details →Li N, Wu C, Cao P et al. · 2024 · Access microbiology
Background Rhodococcus equi is one of the most important causes of zoonotic infections from grazing animals. It poses a particular risk to immunocompromised individuals, including those who are undergoing long-term immunosuppressive…
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