e-ISSN: Pending
WASTE Journal

Browse the failure-mode index

12,368 real negative results, null findings, and replication failures in Medicine. Search the index →

WASTE indexes published research — it does not host or republish full papers. Each entry is a metadata record compiled from open scholarly databases; the abstract is shown in full only where the paper is openly licensed, otherwise a short excerpt under fair use. Classifications are automated and approximate.

Negative / Null Result ReportOpen accessMedicine

Impact of Coronary Lesion Stability on the Benefit of Emergent Percutaneous Coronary Intervention After Sudden Cardiac Arrest

Louis Pechmajou, Éloi Marijon, Olivier Varenne et al. · 2020 · Circulation Cardiovascular Interventions

Background: Conflicting data exist regarding the benefit of urgent coronary angiogram and percutaneous coronary intervention (PCI) after sudden cardiac arrest, particularly in the absence of ST-segment elevation. We hypothesized that the…

View details →
Negative / Null Result ReportOpen accessMedicine

Chemoradiation ± Atezolizumab in Limited-Stage Small Cell Lung Cancer: Results of NRG Oncology/Alliance LU005

Kristin A. Higgins, Chen Hu, Helen J. Ross et al. · 2026 · Journal of Clinical Oncology

PURPOSE NRG Oncology/Alliance LU005 (ClinicalTrials.gov identifier: NCT03811002 ) tested the addition of atezolizumab to concurrent chemoradiation (CRT) in this open-label, phase III international trial. METHODS Patients with limited-stage…

View details →
Negative / Null Result ReportMedicine

Significant effects of lymph and blood vascular invasion on the prognosis of early‐stage cervical squamous cell carcinoma

Yanna Zhang, Ming Yan, Jiehua He et al. · 2010 · Journal of obstetrics and gynaecology research

AIM: In the past 10 years, therapeutic advances have led to improved short-term efficacy for cervical carcinoma; however, the 5-year survival rate was not significantly enhanced. To investigate the effects of blood vessel invasion (BVI)…

View details →
Null DatasetOpen accessMedicine

Causes and Outcomes of Admission and Investigation of Tuberculosis in Adults with Advanced HIV in South African Hospitals: Data from the TB Fast Track Trial

Peter Beckwith, Mpho Tlali, Salome Charalambous et al. · 2021 · American Journal of Tropical Medicine and Hygiene

Tuberculosis (TB) remains the leading cause of hospitalization and in-hospital mortality in HIV-positive adults. Using data from hospital and clinic files, research databases, and autopsy, we describe causes and outcomes of admissions, and…

View details →
Negative / Null Result ReportOpen accessMedicine

Development of a tailored intervention targeting sedentary behavior and physical activity in people with stroke and diabetes: A qualitative study using a co-creation framework

Stefan Sjørslev Bodilsen, Mette Aadahl, Troels Wienecke et al. · 2023 · Frontiers in Rehabilitation Sciences

Purpose: Type 2 diabetes and sedentary behavior pose serious health risks in stroke survivors. Using a co-creation framework, this study aimed to develop an intervention in collaboration with stroke survivors with type 2 diabetes, relatives, and cross-sectoral health care professionals to reduce sedentary behavior and increase physical activity. Materials and methods: = 10) to develop the intervention. A content analysis was used to analyze data. Results: The developed "Everyday Life is Rehabilitation" (ELiR) intervention consisted of a tailored 12-week home-based behavior change intervention

View details →
Negative / Null Result ReportOpen accessMedicine

Does gender have a significant effect on normal nerve conduction studies values?

Kawthar Al-Salmi, Farook S Wali, Ahmed Sameer Nadeem et al. · 2019 · Journal of Neurology & Stroke

Background: nerve conduction study (NCS) is a neurophysiologic medical diagnostic test used commonly to evaluate the function of the peripheral nerves. It is an extension to the clinical examination and extremely useful to diagnose and…

View details →
Negative / Null Result ReportMedicine

The relationship between appetite hormones and body mass index in children with intoxication type metabolic diseases.

Koç, Konyalıgil, Özen Yeşil et al. · 2026 · Orphanet journal of rare diseases

The aim of this study is to comparatively examine the effects of appetite loss and insufficient energy intake, which trigger poor metabolic control parameters, on appetite hormones and body mass index in children with intoxication-type…

View details →
Negative / Null Result ReportMedicine

The Effect of the Temporal Position of a Gap on Its Automatic Detection.

Omidvar, Campbell, Alain et al. · 2026 · The European journal of neuroscience

The presentation of a rarely occurring auditory stimulus that contains a silent interval (or gap) among a sequence of frequently occurring stimuli that do not contain a gap can elicit a negative-going event-related potential known as the…

View details →
Negative / Null Result ReportMedicine

Prognosis of ER-positive, HER2-negative postmenopausal early breast cancer patients based on response to neoadjuvant endocrine therapy and multigene assay results: findings from the NEOS trial.

Iwata, Masuda, Yamamoto et al. · 2026 · Breast cancer (Tokyo, Japan)

We previously reported the 21-gene Oncotype DX® assay results from TransNEOS in patients enrolled in the phase 3 NEOS trial. However, the association between assay results and long-term prognosis has remained unclear. Of the 296…

View details →
Negative / Null Result ReportMedicine

Clinically indicated versus routine replacement of peripheral intravenous cannulas in elderly patients: Secondary analysis of a multi-center randomized controlled trial in mainland China.

Jiang, Wang, Wei et al. · 2026 · Geriatric nursing (New York, N.Y.)

Peripheral Intravenous Cannulas (PIVCs) are extensively used for infusion therapy. Although current evidence suggests that adult patients may have PIVCs removed based on clinical indications, the indication in elderly patients remains…

View details →
Negative / Null Result ReportMedicine

CT Perfusion Blood Flow Provides an Early Response Marker for Progression-free Survival in a Prospective Randomized Clinical Trial of Metastatic Renal Cell Carcinoma.

Ng, Chen, Wei et al. · 2026 · Technology in cancer research & treatment

IntroductionThere is currently no biomarker for progression-free survival (PFS) for patients undergoing treatment for metastatic renal cell carcinoma (RCC). The aim of our study was to evaluate computed tomography perfusion (CTp) blood…

View details →
Negative / Null Result ReportMedicine

The Utility of Large Language Models to Assist With Emergency Triage Decisions Within Otolaryngology.

Hack, Attal, Steckbeck et al. · 2026 · Otolaryngology--head and neck surgery : official journal of American Academy of Otolaryngology-Head and Neck Surgery

To determine whether contemporary large language models can match clinician performance in evaluating the urgency of emergency otolaryngology referrals. Blinded cross-sectional diagnostic reasoning study. Simulated emergency referral…

View details →
Negative / Null Result ReportMedicine

Relation between forearm flexor-pronator muscle elasticity and ulnar collateral ligament laxity of the elbow joint in high school pitchers with and without medial elbow tenderness: evaluation using shear wave elastography.

Tajika, Shitara, Hatori et al. · 2026 · JSES international

The forearm flexor-pronator muscle contributes to the dynamic stabilizer against valgus stress at the elbow during pitching motion. This study used shear wave ultrasonography to assess the relation between the elasticity of each forearm…

View details →
Negative / Null Result ReportMedicine

Differences in gut microbiome of Hanwoo (Korean indigenous cattle) calves as driven by bovine rotavirus and bovine coronavirus infection.

Ku, Lee, Jung et al. · 2026 · Journal of animal science and technology

The gut microbiome of cattle suppresses pathogens and aids host immunity. However, the gut microbiome of newborn calves is still developing; therefore, diarrhea caused by pathogen infection is common. Rapid changes in the gut microbiome…

View details →
Negative / Null Result ReportMedicine

External Validation of a Deep Learning-Based Artificial Intelligence System for Ultrasound Diagnosis of Thyroid Nodules: A Two-Center Retrospective Study.

Tang, Xu, Zhao et al. · 2026 · Journal of clinical ultrasound : JCU

To investigate the performance of an artificial intelligence (AI) diagnostic system for thyroid nodule sonography based on deep learning convolutional neural network (CNN). We retrospectively included 485 thyroid nodules with definite…

View details →
Negative / Null Result ReportMedicine

Robotic vs. open liver resection after neoadjuvant therapy for hepatocellular carcinoma: a propensity score-matched analysis of short- and long-term outcomes.

Zhang, Li, Chen et al. · 2026 · Surgical endoscopy

Neoadjuvant therapy is recommended for hepatocellular carcinoma at advanced stages. It is unknown whether robotic liver resection (RLR) is superior to open liver resection (OLR) after neoadjuvant therapy. We analyzed consecutive RLR and…

View details →
Negative / Null Result ReportMedicine

Association of ultra-processed foods (UPFs) with hypertriglyceridemic waist (HTGW) phenotype, oxidative stress, and inflammation in Iranian adults: a cross-sectional study.

Rostamian, Moabedi, Poursalehi et al. · 2026 · Food & function

In this study, we evaluated the association between UPFs with HTGW in relation to oxidative stress and inflammation in Iranian adults, as no previous study had assessed these altogether. This cross-sectional study consisted of a sample of…

View details →