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WASTE Journal

Browse the failure-mode index

12,240 real negative results, null findings, and replication failures in Medicine. Search the index →

WASTE indexes published research — it does not host or republish full papers. Each entry is a metadata record compiled from open scholarly databases; the abstract is shown in full only where the paper is openly licensed, otherwise a short excerpt under fair use. Classifications are automated and approximate.

Negative / Null Result ReportMedicine

Clinical outcomes of endovascular treatment in patients with large ischemic strokes selected by non-contrast computed tomography within the extended time window.

Jiang, Zhu, Gan et al. · 2026 · European journal of radiology

This study aimed to investigate the effectiveness and safety of endovascular treatment (EVT) in patients with large ischemic strokes assessed by non-contrast CT (NCCT) within the extended time window. This study was a sub-analysis of a…

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Negative / Null Result ReportMedicine

Effect of a Multidimensional Digital Health Intervention on Quality of Life in Breast Cancer Survivors: A Randomized Controlled Trial.

Fuentes-Expósito, Frid, Muñoz-Mateu et al. · 2026 · JCO clinical cancer informatics

We evaluated whether offering access to a multicomponent mHealth app improves quality of life (QoL) and psychosocial outcomes among breast cancer survivors under pragmatic, nonprescriptive conditions. In this single-center, randomized,…

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Negative / Null Result ReportMedicine

7-mm-Diamater Versus 5-mm-Diameter Immediate Post-Extraction Implants in the Molar Region: 1-Year Results from a Multicenter Randomized Controlled Trial.

Esposito, Bocari, Cho et al. · 2026 · The International journal of oral & maxillofacial implants

This multicenter randomized controlled trial compared the clinical effectiveness of 7.0-mm wide-diameter implants with 5.0-mm conventional-diameter implants placed immediately after molar extraction. Thirty-nine patients needing a single…

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Negative / Null Result ReportMedicine

Effects of fermented Arundo donax juice on growth performance, immunocompetence, antioxidant capacity, and intestinal digestive enzyme activity in Arbor Acres broilers.

Li, Ma, Liu et al. · 2026 · Tropical animal health and production

In this study, we used lactic acid bacteria to ferment the byproduct of Arundo donax papermaking, Arundo donax juice (ADJ), to obtain fermented Arundo donax juice (FADJ). We aimed to investigate the effects of FADJ on the growth…

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Negative / Null Result ReportMedicine

Beyond peak wavelength: spectral bandwidth of blue and red-blue laser diodes modulates photosynthesis, canopy architecture, chlorophyll maintenance, and whole-plant growth.

Li, Sugita, Togawa et al. · 2026 · Frontiers in plant science

High planting densities in indoor horticulture often accelerate lower-leaf chlorophyll degradation, increasing trimming frequency, reducing effective photosynthetic area, and raising labor costs. While spectral composition has been widely…

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Negative / Null Result ReportMedicine

Deep and repetitive transcranial magnetic stimulation improves motor dysfunction after basal ganglia infarction: preliminary findings on efficacy and electrophysiological mechanisms.

Yang, Zhu, Chen et al. · 2026 · Frontiers in neuroscience

To observe the therapeutic effects of deep transcranial magnetic stimulation (dTMS) and repetitive transcranial magnetic stimulation (rTMS) on upper and lower limb motor dysfunction in patients with basal ganglia infarction, and to…

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Negative / Null Result ReportMedicine

Connective tissue graft with injectable platelet rich fibrin for treatment of RT1 gingival recession by tunnel technique: a randomized clinical and immunohistochemical study.

Mahmoud, Elrefaei, Shata et al. · 2026 · Frontiers in oral health

The literature regarding the use of injectable platelet- rich fibrin (i-PRF) for root coverage is scarce. Therefore, this RCT aimed to evaluate and compare the effect of using connective tissue graft (CTG) with and without i-PRF using the…

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Negative / Null Result ReportMedicine

Association of achieved LDL-C levels with global coagulability and clinical outcomes in patients with acute coronary syndrome receiving PCSK9 inhibitors: a prospective cohort study.

Fu, Yao, Zhang et al. · 2026 · Frontiers in cardiovascular medicine

The safety of achieving ultra-low low-density lipoprotein cholesterol (LDL-C) levels in acute coronary syndrome (ACS) patients on dual antiplatelet therapy (DAPT), particularly regarding global coagulability, specific platelet reactivity,…

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Negative / Null Result ReportMedicine

Overexpression of PtrPIP2:4 Accelerates Adventitious Root Emergence, Promotes Adventitious Root Elongation, and Increases Lateral Root Number in Poplar.

Cheng, Zhao, Li et al. · 2026 · Plants (Basel, Switzerland)

Plasma membrane intrinsic proteins (PIPs), a subfamily of aquaporins (AQPs), play critical roles in various physiological processes in plants, including the transport of water and CO 2 , regulation of stomatal movement, absorption of…

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Negative / Null Result ReportMedicine

Comparison of Neuromuscular Control Characteristics in Forehand Stroke Between International- and National-Level Squash Players: An sEMG-Based Analysis of Muscle Synergy and Intermuscular Coherence.

Zhang, Wang, Tong et al. · 2026 · Sensors (Basel, Switzerland)

This study aimed to compare the neuromuscular control characteristics of international- and national-level squash players during forehand strokes using a multichannel surface electromyography (sEMG)-based sensing framework. By integrating…

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Negative / Null Result ReportMedicine

Effect of Boswellia serrata on Pain Intensity, Central and Peripheral Sensitization, and Pain Modulation in Healthy Volunteers-A Randomized, Double-Blind, Placebo-Controlled, Cross-Over Pilot Trial.

Hammer, Reiser, Bader et al. · 2026 · Nutrients

Boswellia serrata has traditionally been used in Ayurvedic medicine for its anti-inflammatory and antioxidant properties. Although several studies support clinical analgesic efficacy, the underlying mechanisms have not been investigated in…

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Negative / Null Result ReportMedicine

Remaining Root Filling Material in Oval Canals After Retreatment Using MicroMega Remover and Reciproc Blue Systems with and Without Passive Ultrasonic Irrigation: A Micro-CT Study.

Konus, Oztekin · 2026 · Journal of clinical medicine

Background/Objectives : The aim of this study was to compare the effectiveness of the Reciproc Blue (RB) and MicroMega Remover (MR) systems in removing root canal filling material and to evaluate the effect of passive ultrasonic irrigation…

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Negative / Null Result ReportMedicine

Comparison of Early Postoperative Recovery and Radiologic Outcomes Between Microscopic and Unilateral Biportal Endoscopic Posterior Cervical Foraminotomy for Cervical Radiculopathy.

Han, Lee, Jang et al. · 2026 · Journal of clinical medicine

Objective : This study aimed to compare the clinical and radiological outcomes between microscopic and unilateral biportal endoscopic (UBE) posterior cervical foraminotomy (PCF). Methods : This study included 73 patients who underwent…

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Negative / Null Result ReportMedicine

Effect of Failed Debridement, Antibiotics, and Implant Retention on Subsequent Two-Stage Reimplantation for Periprosthetic Joint Infection Following Total Knee Arthroplasty: A Retrospective Cohort Study.

Kim, Lee, Ko et al. · 2026 · Journal of clinical medicine

Background : Periprosthetic joint infection (PJI) following total knee arthroplasty (TKA) is a serious complication associated with substantial morbidity and healthcare costs. Although two-stage revision arthroplasty is widely accepted as…

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