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WASTE Journal

Browse the failure-mode index

12,240 real negative results, null findings, and replication failures in Medicine. Search the index →

WASTE indexes published research — it does not host or republish full papers. Each entry is a metadata record compiled from open scholarly databases; the abstract is shown in full only where the paper is openly licensed, otherwise a short excerpt under fair use. Classifications are automated and approximate.

Negative / Null Result ReportMedicine

Inhibitory Effects of Oxytocin on Jejunal Migrating Myoelectric Complex Activity in Fasted Rats: Role of Oxytocin and GLP-1 Receptors.

Balcı, Saltık, Aktemur et al. · 2026 · Life (Basel, Switzerland)

The migrating myoelectric complex (MMC) is the electrical basis of fasting small intestinal motility. Although oxytocin (OT) regulates gastrointestinal functions through oxytocin receptors (OTRs), its effect on jejunal MMC activity during…

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Negative / Null Result ReportMedicine

[Impact of tirofiban on outcomes in STEMI patients across different levels of inflammation: a stratified analysis based on complete blood count-derived inflammatory markers].

Lin, Dong, Yang et al. · 2026 · Zhonghua xin xue guan bing za zhi

Objective: To investigate through stratified analyses based on complete blood count-derived inflammatory markers, the effects of tirofiban on in-hospital all-cause mortality and one-year composite endpoint events in patients with…

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Negative / Null Result ReportMedicine

Olfactory notes in the mind space: A registered report.

Caldana M, Rusconi E · 2026 · Cortex; a journal devoted to the study of the nervous system and behavior

Olfaction is an archaic sense but its central mechanisms are lesser known than those of other senses. Here we address a possible link between olfactory stimuli and mental spatial representations. Although olfactory percepts are not…

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Negative / Null Result ReportMedicine

Toxicity assessment of green energy by-product, lithium, using a novel suite of eight Australian aquatic-species tests from a Global Biodiversity Hotspot.

Nice, Storer, Fisher et al. · 2026 · Environmental toxicology and chemistry

Due to recent advances in green energy initiatives in response to climate change impacts, lithium exploration and production are rapidly increasing, with concomitant elevated lithium in discharges to waterways. However, lithium toxicity to…

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Negative / Null Result ReportMedicine

Effect and safety of Neiguan acupoint injection with astragalus injection for chronic heart failure with qi-deficiency and blood-stasis syndrome: a randomized controlled trial.

Gou, He, Zhuo · 2026 · Frontiers in medicine

To investigate the effect and safety of astragalus injection at Neiguan (PC6) for chronic heart failure (CHF; HF) with qi-deficiency and blood-stasis syndrome, and its effect on the renin-angiotensin-aldosterone system (RAAS). A…

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Negative / Null Result ReportMedicine

Does Gestational Diabetes Increase Urinary Incontinence During Pregnancy? A Cross-Sectional Study of Symptom Patterns and Incontinence-Related Quality of Life.

Özel, Efiloğlu, Cim et al. · 2026 · Neurourology and urodynamics

This study aimed to evaluate the association between gestational diabetes mellitus and urinary incontinence during pregnancy, including symptom subtype, symptom severity, and incontinence-related quality of life. This cross-sectional study…

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Negative / Null Result ReportMedicine

Overcoming donor-specific anti-human leukocyte antigen antibodies with desensitisation in adult ex-vivo T-cell depleted haploidentical haematopoietic stem cell transplantation: a real-world analysis.

Tham, Linn, Koh et al. · 2026 · Transplantation and cellular therapy

The presence of anti-human leukocyte antigen (HLA) antibodies directed against donor HLA (HLA-DSA) in HLA-mismatched haematopoietic stem cell transplantation (HCT) can affect engraftment and transplant outcomes. Desensitisation treatment…

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Negative / Null Result ReportMedicine

Knowledge of oxygen therapy among healthcare professionals in non-intubated patients: a cross-sectional study in Somalia.

Duman Aydin, Küçükosman, Mohamed et al. · 2026 · BMC medical education

Although oxygen therapy (OT) is a fundamental and life-saving intervention in the management of hypoxemia, it may lead to serious complications when applied incorrectly or in an uncontrolled manner. The aim of this study is to evaluate the…

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Negative / Null Result ReportMedicine

ClassPass Memberships to Improve Well-Being Among Psychiatry Residents: A Pilot Randomized Controlled Trial.

Yang, Mueller, D'Andrea et al. · 2026 · Academic psychiatry : the journal of the American Association of Directors of Psychiatric Residency Training and the Association for Academic Psychiatry

Resident physicians experience high rates of depression, anxiety, burnout, and loneliness, yet few evidence-based interventions have been evaluated in this population. This randomized controlled pilot trial examined the feasibility,…

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Negative / Null Result ReportMedicine

vNOTES Pelvic Reconstruction and Presacral-Uterosacral Ligament Compound Suspension for Treatment of Multicompartment Pelvic Organ Prolapse: A Three-Year, Three-Arm, Open-Label, Randomized Controlled Trial.

Peng, Wang, Xiao et al. · 2026 · Journal of minimally invasive gynecology

To compare the effectiveness and safety of transvaginal natural orifice transluminal endoscopic surgery (vNOTES) pelvic reconstruction (PRC), vNOTES presacral-uterosacral ligament suspension (PULS), and sacrospinous ligament fixation…

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Negative / Null Result ReportMedicine

Material fracture/retention rates of occluso-proximal composite resin restorations with polyethylene fibers in primary molars: an interim randomized controlled trial.

Rocha, Dos Anjos, Pinho et al. · 2026 · Journal of dentistry

This 12-month, double-blind, parallel, randomized controlled trial compared the material fracture/retention rates of occluso-proximal direct composite resin restorations associated with polyethylene fiber (CR+PF; Ribbond®) with…

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Negative / Null Result ReportMedicine

Generative Artificial Intelligence for Orthognathic Planning: Patient-Specific 3-Dimensional Jaw Reference Forms Conditioned on the Cranial Base.

Kim, Yang, Kuang et al. · 2026 · Journal of oral and maxillofacial surgery : official journal of the American Association of Oral and Maxillofacial Surgeons

Conventional cephalometry relies on measurements derived from a limited set of landmarks and population-based norms, which may not fully capture individual skeletal form. Although evaluated independently, many cephalometric variables…

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Negative / Null Result ReportMedicine

Using a hand-held pupillometer to quantify pupil constriction as part of the accommodation reflex.

Olson, Perera, Kamal et al. · 2026 · Journal of clinical neuroscience : official journal of the Neurosurgical Society of Australasia

Quantitative pupillometry (QP) provides a reliable measure of the pupillary light reflex. The pupil accommodation reflex (P-AR) occurs when there is a change in visual focus from near to far or from far to near. The ability to measure the…

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