12,266 real negative results, null findings, and replication failures in Medicine. Search the index →
WASTE indexes published research — it does not host or republish full papers. Each entry is a metadata record compiled from open scholarly databases; the abstract is shown in full only where the paper is openly licensed, otherwise a short excerpt under fair use. Classifications are automated and approximate.
Lowe BG, Woolgar A, Smit S et al. · 2026 · Cortex; a journal devoted to the study of the nervous system and behavior
Sustaining attention is effortful but crucial for daily life. Despite this, attentional lapses are common and can have fatal consequences (e.g., when driving). The spontaneous nature of these lapses makes studying their underlying…
View details →Klement RJ, Sweeney RA · 2026 · Strahlentherapie und Onkologie : Organ der Deutschen Rontgengesellschaft ... [et al]
Purpose Ketogenic diets (KDs) have been proposed to target glycolytic cancer metabolism and synergize with radio- and chemotherapy. We herein report survival outcomes of rectal and head and neck cancer (HNC) patients who followed a KD…
View details →Peirano G, Walker SD, Duong MS et al. · 2026 · European journal of clinical microbiology & infectious diseases : official publication of the European Society of Clinical Microbiology
Introduction Metallo-β-lactamase (MBL)-producing Enterobacterales are increasing in frequency and treatment options are limited. Aztreonam/avibactam (AZA) and aztreonam (ATM) plus ceftazidime/avibactam (CZA) showed activities against these…
View details →Hayashi T, Mizobuchi K, Higa N et al. · 2026 · Ophthalmic genetics
Purpose To assess the detectability of the pathogenic RP1 Alu insertion using the PrismGuide™ inherited retinal dystrophy (IRD) panel, which targets 82 IRD genes, and whole-exome sequencing (WES). Methods A girl diagnosed with early-onset…
View details →Nichols S, Estandía A, Young CM et al. · 2026 · International journal for parasitology
Parasites are ubiquitous and exert varied ecological and evolutionary pressures on their hosts. Yet, characterising parasite diversity and distributions can be challenging and costly. Leveraging existing data to identify parasites is thus…
View details →He C, Gu X, Liu Y et al. · 2026 · Frontiers in cellular and infection microbiology
Objective This study aims to investigate the impact of mutations within the major hydrophilic region (MHR) of the hepatitis B virus (HBV) S gene on the expression, secretion, and antigenicity of hepatitis B surface antigen (HBsAg), and…
View details →Jimenez CM, Kreizinger Z, Gyuranecz M et al. · 2026 · Poultry science
The control and prevention of Mycoplasma (M.) synoviae infections have been significantly improved by the use of the MS-H live vaccine strain. This vaccine has been used globally for decades; therefore, many technical approaches have been…
View details →Zhang H, Wu W, Xu J · 2026 · Frontiers in oncology
Early ampullary tumors are challenging to diagnose due to their complex surrounding structures and deep anatomical location. We report a rare case in which enhanced computed tomography (CT), magnetic resonance imaging (MRI), magnetic…
View details →An SY, Kim I, Hong SH et al. · 2026 · Protein science : a publication of the Protein Society
Anti-CRISPR (Acr) proteins are phage-encoded anti-defense factors that suppress CRISPR-Cas immunity in bacteria. AcrIIA8 was previously identified as an inhibitor of Streptococcus pyogenes Cas9 (SpyCas9) through functional assays of…
View details →Nie YH, Li Q, Lu YJ et al. · 2026 · Protein expression and purification
C14orf119 is a functionally uncharacterized mitochondrial protein potentially implicated in ischemic stroke pathogenesis. To enable comprehensive biological studies, we developed and validated a specific polyclonal antibody against this…
View details →Hilgendorf J, Calisto V, Cardoso DN et al. · 2025 · Environmental toxicology and pharmacology
Sediments play a key role in chemical partitioning in aquatic ecosystems, acting as sinks for lipophilic and persistent compounds. However, sediment hazard assessment is limited, often underestimating risks by focusing on short-term,…
View details →Ito T, Yoshie T, Yoshimura S et al. · 2025 · Studies in health technology and informatics
In this study, we combined automatically generated labels from large language models (LLMs) with a small number of manual annotations to classify adverse event-related treatment discontinuations in Japanese EHRs. By fine-tuning JMedRoBERTa…
View details →Das D, Chawla B, Lomi N et al. · 2025 · Cureus
Introduction Artificial intelligence (AI) is increasingly being integrated into ophthalmic diagnostics, offering potential for efficient screening of common retinal diseases. The Medios AI system by Remidio (Singapore, Singapore), designed…
View details →Qiu W, Yan YK, Kang JP et al. · 2025 · Clinical laboratory
Background Nucleated red blood cells (NRBCs) play a crucial role in automated blood analysis, particularly in the diagnosis and monitoring of blood disorders. This study examines the limitations of the Sysmex XN-9000 fully automated…
View details →Salahat D, Mujahed R, Jaber M et al. · 2026 · Oxford medical case reports
Tuberous Sclerosis Complex (TSC) is a rare genetic disorder characterized by the development of benign tumors in multiple organs. This report presents an unusual case of early-onset renal cystic disease in a 1-year-old male with TSC,…
View details →Saad F, Shams S, Ayaz S et al. · 2025 · Journal of medical virology
Cytomegalovirus (CMV) poses significant risks to infants and immunocompromised individuals. This study investigated the prevalence, associated risk factors, and phylogenetic profile of CMV DNA in the breast milk of lactating mothers in…
View details →Ueda M, Mitani H, Nakaki Y et al. · 2025 · Interventional radiology (Higashimatsuyama-shi (Japan)
Purpose: To evaluate the performance of automated tumor-feeder detection software in transarterial chemoembolization for hepatocellular carcinoma using angio-computed tomography. Material and Methods: This was a retrospective study of 107…
View details →Mottaghi M, Manda P, Morton EA et al. · 2025 · Cureus
We report the case of a 58-year-old woman who initially presented to the emergency department with intermittent nausea, vomiting, and left upper quadrant abdominal pain for six days. As part of the abdominal pain workup in the emergency…
View details →Smith BJ, Stafne ET, Read QD · 2025 · PhytoFrontiers™
Phytophthora root rot is a major disease of blueberry that relies on cultural practices, including soil amendments, for disease management. We evaluated the effect of three cover crops on the establishment and growth of southern highbush…
View details →Ruiz-Rebollo ML, Muñoz-Moreno MF · 2025 · Medicina clinica
Background Acute pancreatitis can affect elderly people. Conflicting results have been published regarding the role of age in the course of this life-threatening disease. Aim To assess the clinical outcomes of acute pancreatitis in…
View details →Wilmshurst P · 2026 · Clinical medicine (London, England)
One-quarter of adults have a persistent (patent) foramen ovale (PFO). Right-to-left shunting through a PFO can facilitate paradoxical thromboembolism, cryptogenic stroke, paradoxical gas embolism, decompression sickness, arterial…
View details →Wei Q, Wang SA, Garcia-Manero G et al. · 2025 · Modern pathology : an official journal of the United States and Canadian Academy of Pathology, Inc
Identification of cytogenetic abnormalities is critical for the classification and risk stratification of myelodysplastic syndromes (MDS). Optical genome mapping (OGM) is an emerging cytogenomic platform that enables high-resolution…
View details →Noorelahi Y · 2025 · Radiology research and practice
Objective Accurate meniscal tear diagnosis is essential for proper knee injury management. While MRI is the gold standard, ultrasound (US) offers a cost-effective alternative. However, its accuracy compared to arthroscopy remains…
View details →Dachraoui K, Ben Osman R, Ben Slama S et al. · 2025 · Vector borne and zoonotic diseases (Larchmont, N.Y.)
A total of 20 horses belonging to the Pasteur Institute of Tunis used for the production of therapeutic serum antiscorpion venom were tested for the presence of antibodies anti-West Nile virus (WNV) during the 2023 outbreak of West Nile…
View details →Nkoy AB, Mumaka FM, Matoka TT et al. · 2026 · Pediatric nephrology (Berlin, Germany)
Background Serum creatinine (SCr), the most used biomarker to evaluate glomerular filtration rate (GFR), might be inaccurate in children with sickle cell anemia (SCA). In this context, cystatin C (SCys) could be of interest. This study…
View details →Hagenbeek A, Masukagami Y, Palanichamy P et al. · 2026 · BMC genomics
The intracellular endosymbiont Candidatus Lariskella (Alphaproteobacteria, Candidatus Midichloriaceae) has been found across a wide diversity of terrestrial arthropods, including ticks, true bugs, beetles, fleas, wasps and moths. Despite…
View details →Wang Y, Kong X, Wei H et al. · 2025 · Haemophilia : the official journal of the World Federation of Hemophilia
Introduction The Bethesda assay (BA) and the Nijmegen-Bethesda assay (NBA) are commonly used to measure inhibitors in patients with haemophilia A (HA). The laboratory results of inhibitor assays have been demonstrated to be highly…
View details →Hall AD, Whitehurst DA, Mortensen JE et al. · 2025 · Journal of infection and chemotherapy : official journal of the Japan Society of Chemotherapy
Malaria remains a significant public health concern in sub-Saharan Africa, particularly in Ethiopia where Plasmodium falciparum and Plasmodium vivax are co-endemic. Most cases in the United States are acquired abroad and imported.…
View details →Atencia S, Mateu N, Rodríguez-Cobos A et al. · 2025 · Veterinary research communications
Bordetella bronchiseptica (Bb) is a frequent pathogen in dogs and a component of the Canine Infectious Respiratory Disease Complex (CIRDC). However, it can also be detected in the lower respiratory tract of healthy animals, complicating…
View details →Al Sawafi M, Potdar S · 2025 · Trauma case reports
Background Focused Assessment with Sonography for Trauma (FAST) is a cornerstone in the early assessment of trauma patients. However, a negative initial FAST does not always rule out intra-abdominal injury. Case presentation A middle-aged…
View details →