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WASTE Journal

Browse the failure-mode index

12,382 real negative results, null findings, and replication failures in Medicine. Search the index →

WASTE indexes published research — it does not host or republish full papers. Each entry is a metadata record compiled from open scholarly databases; the abstract is shown in full only where the paper is openly licensed, otherwise a short excerpt under fair use. Classifications are automated and approximate.

Negative / Null Result ReportOpen accessMedicine

Looking for Biomarkers Which May Explain Idiopathic Environmental Intolerance Attributed to Electromagnetic Fields (IEI-EMF): Does RF-EMF Exposure Influence Salivary Cortisol Response?

Verrender A, Manley J, Wallace NK et al. · 2025 · Bioelectromagnetics

In order to understand Idiopathic Environmental Intolerance attributed to Electromagnetic Fields (IEI-EMF), it has been argued that it is crucial to test for effects of radiofrequency electromagnetic fields (RF-EMF) on biomarkers, given…

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Negative / Null Result ReportOpen accessMedicine

Repeated Tetrahydrocannabinol Injections Induce Tolerance but Do Not Disrupt Ongoing Behaviour Upon Withdrawal in Male and Female Rats With Inflammatory Pain.

Morgan MM, Hickey CM · 2026 · European journal of pain (London, England)

Background Many people use cannabis to self-medicate for pain. Little is known about the impact of pain on tolerance and spontaneous withdrawal to delta-9-tetrahydrocannabinal (THC), the primary psychoactive compound in cannabis. Our…

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Negative / Null Result ReportMedicine

Variation in Maternal Effort, Activity Budgets, and Feeding Behavior in Wild Saddleback Tamarins (Leontocebus weddelli) in Northwestern Bolivia.

Erb WM, Porter LM, Voyt R et al. · 2025 · American journal of primatology

Among primates, maternal infant care may vary in response to several factors including litter size, reproductive history, and health status. In cooperative breeders, maternal investment may also depend on the amount of help their group…

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Negative / Null Result ReportMedicine

Transition from classic to expanded Denver screening criteria for blunt cerebrovascular injury: lessons from a high-volume level I trauma center.

Casado-Ruiz J, Castaño-Leon AM, García-Escudero L et al. · 2025 · Journal of neurosurgery

Objective Blunt cerebrovascular injuries (BCVIs) are associated with significant morbidity and mortality. To identify patients with BCVI who were undetected using the classic criteria, researchers designed the expanded Denver screening…

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Negative / Null Result ReportMedicine

Childhood poverty and its impact on financial decision making under threat: A preregistered replication of Griskevicius et al. (2011b).

Gladstone JJ, Lehman M, Decker M · 2025 · Journal of experimental psychology. Applied

We investigated the influence of childhood poverty on financial decision making under threat by replicating the findings of Griskevicius et al. (2011b), which found that individuals from lower socioeconomic backgrounds tend to make riskier…

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Negative / Null Result ReportOpen accessMedicine

A Comparison of Vessel Density in Primary Open-Angle Glaucoma and Normal-Tension Glaucoma Patients Using OCT Angiography.

Zehavi-Dorin T, Kutzscher AE, Badr M et al. · 2026 · Clinical ophthalmology (Auckland, N.Z.)

Purpose To compare global peripapillary and perifoveal vessel densities between primary open-angle glaucoma (POAG) and normal-tension glaucoma (NTG) patients with the same glaucoma severity using optical coherence tomography angiography…

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Negative / Null Result ReportOpen accessMedicine

Cognitive Therapy vs. Short-Term Dynamic Psychotherapy in a Community Mental Health Setting: A Preliminary Analysis of Effects in Several Severity Domains.

Gibbons MBC, Kodkany N, Liow Y et al. · 2026 · Clinical psychology & psychotherapy

Objective To investigate the effectiveness of cognitive therapy (CT) and short-term dynamic psychotherapy (STDP) among patients with greater severity, defined in several ways, in a community mental health setting. Method Using data from a…

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Negative / Null Result ReportMedicine

White matter integrity and verbal memory following a first episode of psychosis: A longitudinal study.

Ghanem J, Totzek JF, Henri-Bellemare C et al. · 2025 · Progress in neuro-psychopharmacology & biological psychiatry

Psychotic disorders are heterogeneous disorders for which there is evidence of structural and functional brain abnormalities. The role of white matter integrity, often measured via Fractional Anisotropy (FA), has played a controversial…

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Negative / Null Result ReportOpen accessMedicine

Plasma Neurofilament Light Chain Is Associated with Cognitive Functions but Not Patient-Reported Outcomes in Multiple Sclerosis.

Nicolella V, Novarella F, Falco F et al. · 2025 · Neurology international

Objective We aimed to explore associations between plasma neurofilament light chain (pNfL) and cognition through patient-reported outcomes (PROs) in multiple sclerosis (MS). Methods In this cross-sectional study, we included 211 people…

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Negative / Null Result ReportOpen accessMedicine

Cryoanalgesia to treat phantom limb pain following a trans-femoral (above-knee) amputation: a randomized, sham-controlled pilot study.

Ilfeld BM, Finneran JJ, Abdullah B et al. · 2026 · Regional anesthesia and pain medicine

Background A previous clinical trial applied percutaneous cryoneurolysis to lower limb amputees with phantom pain. The primary outcome measure was negative, but a secondary analysis suggested that patients with a below-knee amputation…

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Negative / Null Result ReportMedicine

Face masks and protection against COVID-19 and other viral respiratory infections: Assessment of benefits and harms in children.

Sandlund J, Duriseti R, Ladhani SN et al. · 2025 · Paediatric respiratory reviews

Mask mandates for children were implemented at schools and childcare centers during the COVID-19 pandemic, and the US continues to recommend masking down to the age of two in certain settings. Medical interventions should be informed by…

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Negative / Null Result ReportOpen accessMedicine

Model-based planning is unaffected by ketamine, antidepressant and internet delivered cognitive behavioural therapy treatments in depression.

Donegan KR, Hossein S, Panny BM et al. · 2025 · Translational psychiatry

Cognitive impairments have been observed in patients with depression. These include deficits in inhibition, shifting, and updating; cognitive processes that are critical for goal-directed control over behavior ('model-based planning').…

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Negative / Null Result ReportOpen accessMedicine

No Impact of COVID-19 Pandemic on Early Mortality for Thyroid Cancer in the US. Comment on Lee et al. Impact of the COVID-19 Pandemic on Thyroid Cancer Surgery. <i>Curr. Oncol.</i> 2024, <i>31</i>, 3579-3590.

Nocini R, Lippi G, Mattiuzzi C · 2024 · Current oncology (Toronto, Ont.)

Thyroid cancer is relatively rare in the general population compared to other malignancies, but its incidence appears to have increased in recent decades [...].

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Negative / Null Result ReportOpen accessMedicine

Cognitive and physiological impacts of psychotherapy incorporating human-equine interactions during substance withdrawal: A scoping review.

Friend MM, Nicodemus MC, Cavinder CA et al. · 2025 · Journal of equine rehabilitation

The use of psychotherapy incorporating equine interaction (PIE) is becoming widely utilized for the treatment of a range of conditions; however, evidence supporting the efficacy of this treatment is highly variable, inconsistently defined,…

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