12,266 real negative results, null findings, and replication failures in Medicine. Search the index →
WASTE indexes published research — it does not host or republish full papers. Each entry is a metadata record compiled from open scholarly databases; the abstract is shown in full only where the paper is openly licensed, otherwise a short excerpt under fair use. Classifications are automated and approximate.
Mei JJ, Zhu JS · 2025 · Medicine
The aim of this study was to assess whether diabetes mellitus is a potential causal factor in the development of meniscal injuries by means of Mendelian randomization (MR). Independent genetic variants strongly associated with diabetes…
View details →Donegan KR, Hossein S, Panny BM et al. · 2025 · Translational psychiatry
Cognitive impairments have been observed in patients with depression. These include deficits in inhibition, shifting, and updating; cognitive processes that are critical for goal-directed control over behavior ('model-based planning').…
View details →Nocini R, Lippi G, Mattiuzzi C · 2024 · Current oncology (Toronto, Ont.)
Thyroid cancer is relatively rare in the general population compared to other malignancies, but its incidence appears to have increased in recent decades [...].
View details →Friend MM, Nicodemus MC, Cavinder CA et al. · 2025 · Journal of equine rehabilitation
The use of psychotherapy incorporating equine interaction (PIE) is becoming widely utilized for the treatment of a range of conditions; however, evidence supporting the efficacy of this treatment is highly variable, inconsistently defined,…
View details →Civile C · 2026 · Perception
This study investigated the role of perceptual learning in the composite face effect (CFE), which is characterized by reduced accuracy in recognizing the top half of a face when it is combined with the bottom half of another face,…
View details →Kerns EV, Engel S, Codner PA et al. · 2026 · PeerJ
Schistocephalus solidus , a parasitic cestode with a multi-host life cycle, reproduces in its terminal host either by outcrossing with similarly sized individuals or selfing. Previous work found that selfing greatly depresses egg hatching…
View details →Dhanani NH, Lyons NB, Lee KH et al. · 2025 · HCA healthcare journal of medicine
Background Biologic mesh is often used in complex hernia repair, but there has been limited clinical evidence to date to support this practice. The aim of this study was to compare clinical and patient-reported outcomes of biologic versus…
View details →Ratner K, Zhu G, Li Q et al. · 2024 · Journal of research on adolescence : the official journal of the Society for Research on Adolescence
Derailment is the sense of being "off-course" in life. But what could this mean for adolescents, who are often establishing identity and self-direction for the first time? We examined the structure and correlates of the Derailment Scale…
View details →Duster NA, Grossestreuer AV, Sorcher JL et al. · 2025 · Pediatric critical care medicine : a journal of the Society of Critical Care Medicine and the World Federation of Pediatric Intensive and Critical Care Societies
Objectives To explore the association of intra-arrest sodium bicarbonate (SB) use with outcomes in pediatric in-hospital cardiac arrest (p-IHCA) when accounting for the timing of initial SB administration. We hypothesized that…
View details →Cao X, Yi H · 2024 · Otology & neurotology : official publication of the American Otological Society, American Neurotology Society [and] European Academy of Otology and Neurotology
Objective The purpose of this study was to investigate the incidence rate and audiological characteristics of sudden sensorineural hearing loss (SSHL) before the COVID-19 pandemic, during the COVID-19 pandemic, and after inactivated…
View details →Saccone G, Berghella V, Gulersen M et al. · 2026 · International journal of gynaecology and obstetrics: the official organ of the International Federation of Gynaecology and Obstetrics
Progesterone plays a key role in the establishment and maintenance of pregnancy and its deficiency has been associated with early pregnancy loss. Progestogen supplementation has therefore been widely investigated as a preventive strategy…
View details →Wöhner S, Luckow J, Brandt M et al. · 2024 · Journal of experimental psychology. Human perception and performance
Semantic context effects in picture naming and categorization tasks are central to the development and evaluation of current models of word production. When pictures are named in a semantically blocked context, response latencies are…
View details →Dexter F, Rolfzen ML, Hoffman J et al. · 2025 · Anesthesia and analgesia
Background Earlier studies have not examined the extent to which reducing postoperative opioid use after patient discharge would improve the quality of life of opioid naïve patients, knowledge needed for economic evaluations of drugs and…
View details →Mortimer AJ, Sander CF, Parmar AR et al. · 2026 · Scientific reports
Gene therapies are promising for diseases previously considered incurable. Adeno-associated virus serotype 9 (AAV9) demonstrates remarkable tropism for motor neurons (MNs) and represents an exciting candidate to target genetic causes of…
View details →Béna J, Lacassagne D, Corneille O · 2025 · Quarterly journal of experimental psychology (2006)
The contribution of uncontrolled processes to evaluative learning has been examined in evaluative conditioning procedures by comparing evaluations of conditioned stimuli between tasks or within tasks but between learning instruction…
View details →Chacón DA, Shrestha S, Dillon BW et al. · 2026 · Neurobiology of language (Cambridge, Mass.)
At first glance, the brain's language network appears to be universal, but languages clearly differ. Does the brain adapt to the specific details of individual grammatical systems? Here, we present a magnetoencephalography (MEG) study on…
View details →Borghi A, Guarneri F, Pacetti L et al. · 2024 · Italian journal of dermatology and venereology
Background The pathophysiology of sensitive skin is largely unknown and no univocal data on the role of the epidermal barrier impairment have been identified. The aim of this study was to assess whether subjects with or without sensitive…
View details →Melini CM, Kikuti M, Yue X et al. · 2026 · Pathogens (Basel, Switzerland)
Porcine reproductive and respiratory syndrome virus (PRRSV)-positive pigs can be exposed to high concentration of gases, such as ammonia and hydrogen sulfide when manure and urine stored in the pits beneath them is agitated and pumped.…
View details →Arcos K, Covarrubias R, Storm BC · 2025 · Behavioral sciences (Basel, Switzerland)
First-generation students can experience a cultural mismatch between their values and those that colleges and universities tend to prioritize. This mismatch can increase cognitive load, leaving fewer resources available for learning.…
View details →Bellew SD, Kahler Z, Hamm J et al. · 2024 · The Journal of emergency medicine
Background In April of 2022, the COVID-19 pandemic resulted in a global shortage of intravenous contrast media (ICM), which led our health care system to implement rationing measures. Study objectives We set out to determine if the…
View details →Freeman SE, Staples AD, Loverich TM et al. · 2025 · Frontiers in global women's health
Introduction Emotion regulation (ER) abilities predict positive outcomes among children. While parenting behaviors that promote young children's ER development have been widely studied, less is known about how a parent's history of early…
View details →Barzaghi L, Paoletti M, Monforte M et al. · 2024 · Muscle & nerve
Introduction/aims Muscle diffusion tensor imaging has not yet been explored in facioscapulohumeral muscular dystrophy (FSHD). We assessed diffusivity parameters in FSHD subjects compared with healthy controls (HCs), with regard to their…
View details →Hackländer RPM, Schlüter H, Rolke AK et al. · 2025 · Experimental psychology
Not all information encountered is equally important to remember. Some information may be valuable, while others may be irrelevant. Importantly, retrieving and acting upon some information may even have negative consequences. Research has…
View details →Robertson I, Taylor D, Chong J · 2025 · Journal of rehabilitation medicine
Background Rehabilitation is vital for optimizing recovery following neurological injuries. However, much of what is done for the paediatric population relies heavily on the adult literature or is based on expert opinion. No previous…
View details →McDonald A, Corbin W · 2025 · Psychology of addictive behaviors : journal of the Society of Psychologists in Addictive Behaviors
Objective Building upon prior research, the present study tested coping motives as a mediator of relations between both negative urgency and internalizing symptoms (depression, anxiety, and stress), and alcohol-related consequences using…
View details →Snippe E, Elmer T, Ceulemans E et al. · 2024 · Journal of consulting and clinical psychology
Objective Despite the importance for understanding mechanisms of change, little is known about the order of change in daily life emotions, cognitions, and behaviors during treatment of depression. This study examined the within-person…
View details →Jones GA · 2025 · Critical criminology
Failure is taboo. Yet as researchers we often encounter failure in the field and engage in confessional conversations with colleagues about 'what went wrong'. Failure is regarded as an unfortunate and unproductive part of research. Better…
View details →Al-Maghrabi M, Mamede S, Schmidt HG et al. · 2024 · Advances in medical education and practice
Background Literature suggest that physicians' high level of confidence has a negative impact on medical decisions, and this may lead to medical errors. Experimental research is lacking; however, this study investigated the effects of high…
View details →Jeffrey CE, Andrews T, Godden SM et al. · 2024 · Journal of dairy science
The primary objective of this cross-sectional observational study was to determine whether bulk tank milk quality, udder health, udder hygiene, and milk production outcomes were associated with facility type on organic dairies. A secondary…
View details →Vollebregt PF, Goh YL, Bagul A et al. · 2025 · Colorectal disease : the official journal of the Association of Coloproctology of Great Britain and Ireland
Aim Sacral neuromodulation (SNM) is considered the first-line surgical treatment in adults with refractory faecal incontinence (FI). However, its clinical efficacy has not been rigorously tested in a trial setting. Method Randomised,…
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