12,266 real negative results, null findings, and replication failures in Medicine. Search the index →
WASTE indexes published research — it does not host or republish full papers. Each entry is a metadata record compiled from open scholarly databases; the abstract is shown in full only where the paper is openly licensed, otherwise a short excerpt under fair use. Classifications are automated and approximate.
Patel SA, Roy JM, Musmar B et al. · 2024 · Neurosurgical focus
Objective Preclinical studies suggest that robotic carotid artery stenting (CAS) could be superior to manual CAS. However, very limited comparative data exist for patients who have undergone robotic versus manual CAS. In addition, no data…
View details →Goudman L, Pilitsis JG, Billet B et al. · 2024 · Anaesthesia
The numerical rating scale and visual analogue scale are used to quantify pain intensity. However, it has not yet been explored whether these scores are interchangeable in adults with chronic pain. Data from the prospective multicentre…
View details →Millan B, Hoogenes J, Uy M et al. · 2025 · Canadian Urological Association journal = Journal de l'Association des urologues du Canada
Introduction We aimed to assess early and late continence rates post-robot-assisted radical prostatectomy (RARP), comparing posterior reconstruction (PR) urethrovesical anastomosis (UVA) to conventional urethrovesical anastomosis (C-UVA).…
View details →Caldani S, Khoury E, Delorme R et al. · 2025 · Brain sciences
Background/Objectives: Children with dyslexia report poor motor control; several studies have shown poor eye movements control during reading and important body instability in these children. The present study aimed to test in children…
View details →Egger M, Bergmann J, Krewer C et al. · 2024 · Journal of neurologic physical therapy : JNPT
Background and purpose Functional recovery after stroke is often limited, despite various treatment methods such as robot-assisted therapy. Repetitive sensory stimulation (RSS) might be a promising add-on therapy that is thought to…
View details →Vuppu DP, Rajanbabu A, Nair IR et al. · 2025 · Ecancermedicalscience
The latest International Federation of Gynaecology and Obstetrics (FIGO) staging for endometrial cancer incorporated molecular profiles and histopathological factors into the basic staging framework. This study was done to determine its…
View details →Marouf SP, Meskar Z, Rezaei N · 2026 · Discover oncology
Insulin resistance (IR) has emerged as a metabolically relevant contributor to the development and progression of breast cancer (BC), with a case fatality of nearly 15%. IR mainly shows a relationship with obesity, type 2 diabetes mellitus…
View details →Ariizumi Y, Asakage T · 2024 · Japanese journal of clinical oncology
Olfactory neuroblastoma is a rare sinonasal malignancy arising from the olfactory epithelium that is characterized by skull base involvement and a modest natural history. Because of its rarity and long course, identification of independent…
View details →Listiyani P, Sanjaya R, Nathanael J et al. · 2025 · Molecular and cellular biochemistry
T2DM is a serious global health problem and usually caused by unhealthy diet, such diet with high carbohydrate or monosodium glutamate (MSG). In this study, we used the T2DM mice (BALB/c) model by exposing the mice with foods high in…
View details →Markar S, Markar S, Mariette C et al. · 2025 · Diseases of the esophagus : official journal of the International Society for Diseases of the Esophagus
Background Malnutrition is common with esophagogastric cancers and is associated with negative outcomes. We aimed to evaluate if immunonutrition during neoadjuvant treatment improves patient's health-related quality of life (HRQOL) and…
View details →Perugini A, Iandoli J, Pelz N et al. · 2025 · Trauma surgery & acute care open
Background Segmental rib fractures in blunt thoracic trauma present with increased morbidity and mortality with an association of increased pulmonary insult and concomitant injuries. There is a paucity within the literature regarding the…
View details →Zhang LY, Li QJ, Zhou Q et al. · 2025 · International journal of ophthalmology
Aim To determine whether chronic smoking affects fundus blood flow density using optical coherence tomography angiography (OCTA) based on artificial intelligence (AI). Methods All participants underwent a comprehensive ophthalmological…
View details →Kutukoglu MU, Altuntas T, Sekerci CA et al. · 2025 · BMC pediatrics
Background To demonstrate that the CA19-9/creatinine level could be a potential biomarker in children with obstruction by including ureteropelvic junction obstruction (UPJO) patients and comparing them not only with healthy controls but…
View details →Sharma S, Narwariya KS, Shakya R et al. · 2025 · Bioinformation
Acute intestinal obstruction presents a clinical challenge, and the optimal management approach remains uncertain. Therefore, it is of interest to compare outcomes of conservative versus surgical management in 100 patients with acute…
View details →Sinka GC, Pavlik A, Mayer Á et al. · 2026 · Sports (Basel, Switzerland)
Background Anterior cruciate ligament (ACL) injuries in youth athletes are multifactorial, and the relative contributions of neuromuscular and neurocognitive variables remain inadequately comprehended. Methods In this prospective cohort…
View details →Abushouk A, Layoun H, Harb SC et al. · 2024 · Journal of cardiac failure
Novel transcatheter therapies for tricuspid regurgitation (TR) appear promising, yet their applicability to an all-comer TR population remains unclear. We aimed to assess the feasibility of emerging transcatheter tricuspid therapies in a…
View details →Cardani S, Janes TA, Asif R et al. · 2026 · Acta physiologica (Oxford, England)
Aim Rhythmic breathing movements driven by the brainstem rely on chemosensory inputs to homeostatically adjust motor output to the prevailing metabolic demand. The central CO 2 chemoreflex is a critical component of this neural circuitry,…
View details →Chaccour C, Nicolas P, Martinho S et al. · 2025 · EClinicalMedicine
Background Endectocides are a novel vector control tool that reduce the survival and fertility of blood sucking arthropods that feed upon treated humans or animals. Ivermectin mass drug administration is under evaluation as a complementary…
View details →Antunes FTT, Gadotti VM, Zamponi GW · 2025 · Molecular brain
Alpha-bisabolol and camphene have demonstrated analgesic effects in inflammatory pain models by blocking Cav3.2 calcium channels. As the pain pathway overlaps with mechanisms for itch, and because Cav3.2 channels have been associated with…
View details →Yang W, Ding X, Yu Y et al. · 2024 · Clinical radiology
Aims To investigate the long-term prognostic value of coronary computed tomography angiography (CCTA)-derived high-risk attributes and radiomic features of pericoronary adipose tissue (PCAT) in diabetic patients for predicting major…
View details →Deering TF, Reiffel JA, Solomon AJ et al. · 2023 · The American journal of cardiology
Atrial fibrillation (AF) is a potentially serious health risk, both because of its symptoms and because of its association with an increased risk for heart failure, hospitalization, thromboembolism, and death. Chapter 2 discusses selection…
View details →Hamby M, Egleston BL, Frosch ZAK et al. · 2026 · Blood cancer journal
Plasmablastic lymphoma (PBL) is a rare, aggressive AIDS-related lymphoma observed in patients with immunosuppressed states as well as in immunocompetent individuals. We sought to determine survival outcomes, prognostic factors, and optimal…
View details →Bhuvana J, Shivhare V, Rath S et al. · 2025 · Journal of cancer research and therapeutics
Objectives Medullary thyroid carcinoma (MTC) accounts for only about 5% of total thyroid cancers. It usually presents as an advanced disease carrying a poor prognosis than well-differentiated thyroid cancers. While the treatment of choice…
View details →Park SK, Chung Y, Oh CM et al. · 2026 · Gut and liver
Background/aims Studies have demonstrated that gastroesophageal reflux disease has an unfavorable effect on sleep. However, it is largely unknown whether erosive esophagitis (EE) is associated with sleep issues. Methods Study participants…
View details →Cheng CM, Tsai MJ, Tseng CC et al. · 2026 · Journal of the Chinese Medical Association : JCMA
Agitation is a frequently occurring and challenging neuropsychiatric symptom of Alzheimer's disease (AD) that substantially affects quality of life, caregiver burden, and healthcare utilization. Nonpharmacological interventions, especially…
View details →Stitt GA, Hall MW, Diliberto MA et al. · 2025 · The journal of pediatric pharmacology and therapeutics : JPPT : the official journal of PPAG
Objectives Primary objective: to quantify tocilizumab (TCZ) use in pediatric inpatients. Secondary objectives: to explore safety and clinical outcomes. Methods This retrospective cohort study took place in a free-standing, 564-bed…
View details →Kern DM, Bohn J, Maher MP et al. · 2026 · BMJ open
Objective To use best practices in pharmacoepidemiology to assess the association between new use of brain-penetrant calcium channel blockers (BP-CCBs) compared with use of non-brain-penetrant CCBs (NP-CCBs) and the incidence of…
View details →Deodato M, Melcher D · 2024 · Journal of cognitive neuroscience
The brain organizes the continuous flow of sensory input by parsing it into discrete events. In the case of two flashes separated by a brief ISI, for example, perception may be of a single flash or two distinct flashes, depending on the…
View details →Ambasta A, Grenet G, Otte J et al. · 2025 · African journal of primary health care & family medicine
Thyroid hormones regulate essential metabolic processes and development. The hypothalamic-pituitary-thyroid axis regulates hormone production, with thyroid-stimulating hormone (TSH) levels being a key indicator of thyroid function in…
View details →Neul JL · 2024 · The Journal of clinical investigation
Fragile X syndrome (FXS), the most common inherited cause of intellectual disability and the single-gene cause of autism, is caused by decreased expression of the fragile X messenger ribonucleoprotein protein (FMRP), a ribosomal-associated…
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