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Browse the failure-mode index

12,264 real negative results, null findings, and replication failures in Medicine. Search the index →

WASTE indexes published research — it does not host or republish full papers. Each entry is a metadata record compiled from open scholarly databases; the abstract is shown in full only where the paper is openly licensed, otherwise a short excerpt under fair use. Classifications are automated and approximate.

Negative / Null Result ReportMedicine

Effect of Thermal Processing on the Nutritional Composition and Bioactive Compounds of 'Largueta' Almonds (<i>Prunus dulcis</i>).

Fernández-León MF, Flórez Acosta LR, Fernández-León AM · 2026 · Foods (Basel, Switzerland)

Almond ( Prunus dulcis ) is a highly nutritious nut, rich in unsaturated fatty acids, fibre, and bioactive compounds such as tocopherols, phenolic compounds, and carotenoids. Processing methods commonly applied in the almond industry,…

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Negative / Null Result ReportMedicine

Evaluation of the first edition of the 'Spirituality in medicine' programme implemented for medical students at the Nicolaus Copernicus University, Collegium Medicum in Bydgoszcz, Poland. Pre- and post-test research.

Fopka-Kowalczyk M, Krajnik M · 2026 · BMC medical education

Background This article presents an evaluation of the first obligatory programme on 'Spirituality in Medicine' for medical students in Poland, implemented at the Collegium Medicum in Bydgoszcz of the Nicolaus Copernicus University in…

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Failed Experiment ReportMedicine

Effects of a 15-week recreational football programme on insulin resistance and glycaemic control in inactive premenopausal women with mild arterial hypertension: A randomised controlled trial.

Póvoas S, Castagna C, Connolly LJ et al. · 2026 · Journal of sports sciences

This study aimed to investigate the impact of a 15-week recreational football intervention on insulin resistance and glycaemic control in inactive premenopausal women with mild hypertension. A total of 41 women, aged 35-50 years, were…

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Failed Experiment ReportOpen accessMedicine

A comparison of student evaluations of teaching and learning in the inverted classroom model versus traditional lectures in dental education.

Reuter AK, Deschner J, Schütz L et al. · 2026 · BMC medical education

Introduction The inverted classroom model (ICM) is a learner-centred approach that aims to promote engagement, independence and deeper understanding by shifting knowledge acquisition to self-directed learning before class and using class…

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Failed Experiment ReportMedicine

Reflectance confocal microscopy for monitoring treatment response in superficial basal cell carcinoma: diagnostic challenges due to scar formation.

Clark M, Wuennenberg J, Maghfour J et al. · 2026 · Clinical and experimental dermatology

Background Reflectance confocal microscopy (RCM) criteria for the in vivo diagnosis of superficial basal cell carcinoma (sBCC) lesions have been validated, with studies indicating a high level of diagnostic sensitivity. However, there…

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Negative / Null Result ReportMedicine

Hepatic inflammation after exposure to a mixture of low-dose arsenic and cadmium in a murine model of fatty liver disease.

Subramaniam NK, Gagnon N, Guilbert C et al. · 2026 · Toxicological sciences : an official journal of the Society of Toxicology

Metabolic dysfunction-associated steatotic liver disease (MASLD) is a growing global health burden and major contributor to chronic liver disease. Evidence suggests arsenic (As) and/or cadmium (Cd) exposure may influence MASLD development,…

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Negative / Null Result ReportMedicine

Test-Retest reliability of performance, knee functionality and movement quality biomechanics in agility T-test using markerless motion capture.

Wen Z, Claeys K, García JG et al. · 2026 · Journal of electromyography and kinesiology : official journal of the International Society of Electrophysiological Kinesiology

The purpose of this study was to assess reliability of performance, knee functionality and movement quality parameters in agility T-test using markerless motion capture. Seventeen healthy participants performed two sessions of agility…

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Negative / Null Result ReportMedicine

Heterogeneous rebound patterns of foodborne diseases after COVID-19 non-pharmaceutical interventions, South Korea, 2005-2024.

Kim S, Chun BC · 2026 · International journal of infectious diseases : IJID : official publication of the International Society for Infectious Diseases

Objectives To characterize pathogen-specific patterns of foodborne diseases across the full COVID-19 pandemic period, including post-non-pharmaceutical intervention (NPI) relaxation through 2024. Methods We conducted interrupted time…

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Negative / Null Result ReportMedicine

Effects of a Self-Management Program for Temporomandibular Myalgia in Patients With Fibromyalgia: A Single-Arm Study.

Ferrández-Gómez JE, Baño-Alcaraz A, Gacto-Sanchez M · 2026 · Pain management nursing : official journal of the American Society of Pain Management Nurses

Purpose Myogenic temporomandibular disorder frequently co-occurs with fibromyalgia and is associated with pain, disability, and maladaptive pain cognitions. This study evaluated the short- and long-term effects of an online Pain…

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Negative / Null Result ReportMedicine

Angiotensin (1-7) exaggerates albuminuria and nephrin gene expression but does not modulate renal function-specific microRNAs expressions in kidneys of db/db mice.

Malatiali S, Khamisi S, Kilarkaje N · 2026 · Acta diabetologica

Aim This study investigated the effects of angiotensin (1-7) on diabetes-induced renal injury and renal miRNA levels in obese type 2 diabetic db/db mice. Methods Treatment with angiotensin (1-7) (500 μg/kg; i.p.) was started when the mice…

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Negative / Null Result ReportMedicine

Effect of different positions of lumbar traction on pain, function, and range of motion in adults with non-specific low back pain: a randomized clinical trial.

Mahmoud WS, Alhowimel A, Almotery A et al. · 2026 · Scientific reports

Non-specific low back pain (NSLBP) represents about 80-95% of all LBP cases, yet the optimal lumbar traction position for effective treatment remains debated. To investigate the effect of different positions during lumbar traction on pain,…

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Negative / Null Result ReportMedicine

Thermographic response to acute muscle fatigue and delayed onset soreness (DOMS) following a protocol until exhaustion with concentric exercises in the triceps suralis.

Cabizosu A, Zoffoli A, Mevi R et al. · 2026 · Physiological measurement

Objective. Infrared thermography is projected as an innovative and very promising tool for the observation of muscle response to fatigue. The aim of this study was to observe the skin temperature (Tsk) by thermography about acute muscle…

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Negative / Null Result ReportMedicine

Changes in sulphur content, uptake, internal efficiency index, harvest index and N:S ratio in pea plants from the four-leaf stage to full maturity.

Wysokinski A, Wiśniewska-Kadżajan B, Łozak I · 2026 · BMC plant biology

Background Sulphur is an important macronutrient for legume plants because it influences the formation and functioning of root nodules, the activity of enzymes reducing molecular nitrogen to available forms for plants, the formation of…

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Negative / Null Result ReportMedicine

Clinical course of Graves' orbitopathy in children with newly diagnosed hyperthyroidism: a prospective observational study.

Tepe D, Deligozoglu D, Baskan C et al. · 2026 · Journal of pediatric endocrinology & metabolism : JPEM

Objectives Although Graves' orbitopathy (GO) in childhood is generally considered milder than in adults, data regarding its clinical course and relationship with thyroid autoimmunity remain limited. This study aimed to evaluate the…

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