Negative / Null Result ReportOpen accessMedicine
Özen GY, Özen AK, Bilge NH · 2026 · Diagnostics (Basel, Switzerland)
Background: The anatomical position of the hyoid bone and the morphological characteristics of the soft palate play a key role in upper airway patency, craniofacial balance, and the coordination of functional structures. These features may…
View details →Negative / Null Result ReportMedicine
Clarke G, Shuweihdi F, Relton SD et al. · 2026 · The British journal of general practice : the journal of the Royal College of General Practitioners
Background Primary palliative care is symptom support and care for people with life-limiting illnesses incorporated within standard primary care. Early identification of needs is best practice. There is limited research concerning…
View details →Negative / Null Result ReportOpen accessMedicine
Hallab A · 2026 · Thyroid research
Thyroid hormones modulate brain structures during neurogenesis and impact cognition and emotions during the lifetime. Hypothyroidism is commonly associated with lower gray matter volume. Fewer studies, however, highlighted significant…
View details →Negative / Null Result ReportMedicine
Ojo EO, Xie R, Ng BP et al. · 2026 · Research in gerontological nursing
Purpose The current study aimed to examine the association between cognitive function, fear of falling, and physical activity and assess the moderating effect of physical activity on the association between cognitive function and fear of…
View details →Negative / Null Result ReportMedicine
Dornelas R, Marins I, Rodrigues TS et al. · 2025 · Journal of voice : official journal of the Voice Foundation
Objective To analyze the auditory perception of Korean pop (K-pop) singers' voices to identify vocal characteristics associated with gender neutrality. Study design This is a cross-sectional observational study. Methods The inclusion…
View details →Negative / Null Result ReportOpen accessMedicine
Sugimoto K, Minami T, Nukaya T et al. · 2025 · Cancer diagnosis & prognosis
Background/aim Immune checkpoint inhibitors (ICIs) have improved survival in metastatic renal cell carcinoma (mRCC), with nivolumab (NIVO) plus ipilimumab (IPI) showing benefits in intermediate- and poor-risk patients. Despite first-line…
View details →Negative / Null Result ReportMedicine
Matouskova L, Kralova R, Parobkova E et al. · 2026 · Andrology
Background Despite robust data showing strong potential to improve diagnosis and disease monitoring in testicular germ cell tumors (TGCTs), miR-371a-3p testing has not yet been implemented in routine clinical practice. Cell-free DNA…
View details →Negative / Null Result ReportOpen accessMedicine
Sakulsriprasert P, Bunprajun T, Hengsomboon N et al. · 2026 · Scientific reports
This study evaluated floor and ceiling (F/C) effects within the Tampa Scale for Kinesiophobia (TSK) and examined item-level correlations with total TSK scores and pain intensity in individuals with knee osteoarthritis (KOA). A…
View details →Failed Experiment ReportMedicine
Düsünen E, Tural E, Yonak AK et al. · 2026 · The National medical journal of India
Background Diabetic foot ulcers are an important problem for people with diabetes mellitus. We aimed to determine the mortality rate in patients with diabetic foot ulcers and assess the relationship between mortality, the Wagner…
View details →Negative / Null Result ReportMedicine
Meade-Aguilar JA, Stovall R, Ramiro S et al. · 2026 · Joint bone spine
Objectives There are limited data on how NSAID use and dosage influence hypertension risk in axial spondyloarthritis (axSpA). We evaluated the association between NSAID use and incident hypertension in a longitudinal axSpA inception…
View details →Negative / Null Result ReportOpen accessMedicine
Gonzalez DE, Dickerson BL, Hines K et al. · 2026 · Sports (Basel, Switzerland)
There are concerns that high-dose and/or long-term creatine monohydrate supplementation (CrM) leads to greater side effects (SEs) compared to placebo. This analysis investigated whether the dose or duration of CrM was associated with SEs.…
View details →Negative / Null Result ReportMedicine
Aljarallah S, Aldeligan SH, Almarshed A et al. · 2026 · Neurological sciences : official journal of the Italian Neurological Society and of the Italian Society of Clinical Neurophysiology
PURPOSE.: Restless legs syndrome (RLS) is a common but under-recognised non-motor symptom in multiple sclerosis (MS), potentially linked to central nervous system lesion distribution. This study aimed to assess the anatomical distribution…
View details →Negative / Null Result ReportMedicine
Yıldız P, Yurtseven A, Turan C et al. · 2026 · BMC pharmacology & toxicology
Methylphenidate is widely prescribed for attention-deficit/hyperactivity disorder, and its use has increased substantially in recent years. Although generally considered safe within therapeutic ranges, supratherapeutic ingestion may result…
View details →Negative / Null Result ReportMedicine
Haksever M, Taşdemir D · 2026 · BMC pregnancy and childbirth
To evaluate the association between maternal hemoglobin and ferritin levels and fetal cortical maturation assessed by neurosonography between 30 and 34 weeks of gestation. This prospective observational study included 187 singleton…
View details →Negative / Null Result ReportOpen accessMedicine
Kaushik A, Jaiswal A, Priya B et al. · 2025 · Journal of family medicine and primary care
Background Breast cancer is the most common cancer in women across the world. Immune cells can detect and destroy cancer cells. However, cancer cells acquire certain immune evasion mechanisms such as PD-1+ T-cells, to combat immune…
View details →Negative / Null Result ReportOpen accessMedicine
Zhou X · 2026 · Translational psychiatry
Low titers of blood circulating natural anti-NMDAR1 autoantibodies were reported in ~10% of the general human population. Their potential effects on NMDAR functions in the brain, however, remain unknown. We developed a new method to more…
View details →Negative / Null Result ReportOpen accessMedicine
Hiroshimaya T, Iwai K, Marutani M et al. · 2026 · Scientific reports
This study aimed to clarify the relationship between periodontitis and non-alcoholic fatty liver disease (NAFLD). A survey was conducted with 2,453 participants who visited the dental clinic at the Asahi University Hospital. Periodontitis…
View details →Replication FailureOpen accessMedicine
Amuji DN, Iweala EEJ · 2026 · BMC cancer
BACKGROUND: Breast cancer (BC) is a major cause of cancer-related mortality among women worldwide. Genetic polymorphisms, such as those in the Mesenchymal Epithelial Transition factor (MET) proto-oncogene, may influence cancer risk and…
View details →Replication FailureOpen accessMedicine
Liu Y, Zhong S, Zhong K et al. · 2026 · Frontiers in endocrinology
Aim To investigate the association between history of gestational diabetes mellitus (GDM) and the risk of hypertensive disorders of pregnancy in subsequent pregnancy (s-HDP). Methods A retrospective cohort of 5, 928 women with two…
View details →Negative / Null Result ReportOpen accessMedicine
Haddad A, Zabari Parnis E, Stein N et al. · 2026 · Vaccines
Background/Objective : The emergence of the COVID-19 pandemic has raised significant concerns regarding its impact on immune-mediated diseases, particularly with respect to disease induction and exacerbation. We aimed to investigate the…
View details →Negative / Null Result ReportMedicine
Wu Z, He S, Zhu F et al. · 2026 · Frontiers in endocrinology
Objective Copper overload has been implicated in impaired β -cell function and insulin resistance through oxidative stress and inflammatory pathways. As a major lipoprotein component involved in lipid oxidation, apolipoprotein B (apoB) may…
View details →Negative / Null Result ReportOpen accessMedicine
Macian N, Dualé C, Delay M et al. · 2026 · European journal of pain (London, England)
Background Fibromyalgia is a syndrome characterised by widespread chronic pain, which is believed to be mediated by a state of central sensitisation (CS). Based on the hypothesis that CS itself could have genetic determinants, our aim was…
View details →Negative / Null Result ReportOpen accessMedicine
Alharthy N, Alreefi M, Alsenani M et al. · 2026 · Pediatric health, medicine and therapeutics
Background Among children younger than 5 years, infectious conditions account for the majority of pediatric emergency department visits. Due to nonspecific presentation, early identification of Sepsis and serious bacterial infection is…
View details →Negative / Null Result ReportMedicine
Önder N, Muratoglu K · 2026 · Food additives & contaminants. Part A, Chemistry, analysis, control, exposure & risk assessment
Peanuts are among the most clinically important food allergens and may cause severe reactions even at very low exposure levels. This study investigated the presence of peanut residues in packaged baby biscuits marketed on the European side…
View details →Negative / Null Result ReportMedicine
Mirmosayyeb O, Barzegar M, Rezaei M et al. · 2026 · Neurologia
Purpose Multiple sclerosis (MS) is a debilitating disease accompanied by physical and mental comorbidities. Little is known about the relation between different comorbidities and health-related quality of life (HRQOL) in people with MS…
View details →Negative / Null Result ReportMedicine
Kanani P, Shinde V, Bhimani K et al. · 2026 · Annals of African medicine
Background Shock is a critical, life-threatening syndrome defined by a state of global hypoperfusion that results in inadequate oxygen and nutrient delivery to tissues, leading to cellular dysfunction and ultimately, organ failure. Despite…
View details →Negative / Null Result ReportOpen accessMedicine
Kądziela M, Migdalska-Sęk M, Domańska-Senderowska D et al. · 2026 · International journal of molecular sciences
Vitiligo is a chronic autoimmune skin disorder characterized by progressive melanocyte loss and depigmented skin lesions, whose pathogenesis has been attributed to genetic and immunological factors. The aim of this exploratory study was to…
View details →Negative / Null Result ReportMedicine
Anderson N, Kimlin K, O'Rourke JL et al. · 2026 · Pediatric research
Background Congenital hearing loss can significantly affect childhood development, yet more than half of affected infants present without identifiable risk factors. A possible association between maternal diabetes and congenital hearing…
View details →Negative / Null Result ReportMedicine
Li Y, Zhu YX, Qiu Y et al. · 2026 · Clinical nephrology
Objective The association between the atherogenic index of plasma (AIP) and chronic kidney disease (CKD) among individuals with different metabolic syndromes remains inadequately characterized. The aim of this study is to assess the…
View details →Negative / Null Result ReportMedicine
Mostofi K, Caragliano G · 2026 · The Journal of hospital infection
Background Surgical site infections (SSIs) are a major complication of spinal surgery. The influence of tattoos overlying the operative incision has not been previously evaluated as a risk factor in this context. Methods Retrospective…
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