12,263 real negative results, null findings, and replication failures in Medicine. Search the index →
WASTE indexes published research — it does not host or republish full papers. Each entry is a metadata record compiled from open scholarly databases; the abstract is shown in full only where the paper is openly licensed, otherwise a short excerpt under fair use. Classifications are automated and approximate.
Cheng V, Sayre EC, Amiri N et al. · 2026 · Journal of autoimmunity
Objectives While targeted synthetic disease-modifying antirheumatic drugs (tsDMARDs) have advanced autoimmune disease management, the paucity of perinatal safety data limits evidence-based decision-making in pregnancy. We aimed to…
View details →Berto LG, da Silva CL, Durante MV et al. · 2026 · Pediatric surgery international
Objective Acute appendicitis is the leading cause of abdominal surgery. This study evaluated outcomes of transumbilical single-incision laparoscopic appendectomy (TSILA) compared with conventional laparoscopy and open surgery. Methods A…
View details →Alogaili MH, Hussein ZA, Alsallami AA et al. · 2026 · BMC medical education
Background Time management involves using time efficiently to complete specific tasks and the grade point average (GPA) is a summary statistic that represents students' average academic performance over a specific period. Both the…
View details →Ji J, Sun CL, Dale W et al. · 2026 · GeroScience
Among older adults with early breast cancer, the risk of chemotoxicity can vary widely despite similar chronological age. Here, we evaluated whether epigenetic indicators of biological age can stratify the risk of chemotoxicity in this…
View details →Götz N, Völkerer A, Hofer H et al. · 2026 · Scandinavian journal of gastroenterology
Background Barrett's esophagus (BE) is a premalignant condition associated with gastroesophageal reflux disease (GERD) and an increased risk of esophageal adenocarcinoma (EAC). While Helicobacter pylori ( H. pylori ) has been proposed as a…
View details →Benvenuti L, Digennaro V, Colangelo A et al. · 2026 · European journal of orthopaedic surgery & traumatology : orthopedie traumatologie
Purpose The influence of polyethylene (PE) insert thickness on long-term implant survival after total knee arthroplasty (TKA) remains controversial. Thicker PE inserts are generally reserved for cases in which adequate ligament balance…
View details →Garcia-Ruiz MP, Torres-Bautista RM, Lopez-Franco MD et al. · 2026 · Journal of clinical medicine
Objectives: The general objective of the study was to analyze the influence of sociodemographic factors and care and hygiene practices on the appearance of Incontinence-Associated Dermatitis (IAD). The specific objectives were to identify…
View details →Wu W, Fan Y · 2026 · Medicine
Anesthesia is indispensable to modern surgical practice and clinical care; however, its potential impact on neurodevelopment and behavioral outcomes has raised growing concerns. Discrepancies among previous studies may partly arise from…
View details →Dorofte L, Davidsson S, Carlsson J et al. · 2026 · Cancers
Background Penile squamous cell carcinoma is an uncommon neoplasm that arises via two carcinogenic pathways, one linked to HPV infection and the other to chronic inflammation and p53 alterations. Objective/methods We assessed the…
View details →Devlin H, Bedi R · 2026 · British dental journal
Aims To assess whether area-level deprivation predicts the population-adjusted distribution of National Health Service (NHS) dental practices within a socioeconomically diverse English local authority.Methods Analysis of dental practice…
View details →Parveen A, Jatoi R, Haya A et al. · 2026 · Cureus
Background and aim Postpartum depression (PPD) is a mental health condition that adversely affects both maternal and infant well-being. Kangaroo Mother Care (KMC), involving skin-to-skin contact and exclusive breastfeeding, has shown…
View details →Izquierdo JA, Kerbel J, Apodaca G et al. · 2026 · Cureus
Background Intraoperative periprosthetic femoral fracture is an uncommon but clinically significant complication of total hip arthroplasty (THA) that may compromise implant stability and increase the risk of early revision surgery. Several…
View details →Wang Y, Zhang Y, Lan Y · 2026 · Scientific reports
The mental health of young people serves as a social barometer, reflecting societal conditions. However, the relationship between social inequality and youth mental health remains a contested issue. This study uses data from the China…
View details →Chen Z, Zhang L, Liang Y et al. · 2026 · Digestive diseases and sciences
Background and aims Post-ESD esophageal stricture remains a major complication despite steroid prophylaxis. Temporary stent placement has been proposed as an adjunctive strategy in high-risk cases, yet its independent effect remains…
View details →Yubaitsa CN, Gani KS, Mitchel M et al. · 2026 · Cureus
Background Musculoskeletal problems in the elderly pose a significant challenge for healthcare providers, as they constitute a vulnerable group. Fractures are often undetected, leading to a reduced quality of life due to increased…
View details →Bastian MB, Kyriakou I, Rosar F et al. · 2026 · The quarterly journal of nuclear medicine and molecular imaging : official publication of the Italian Association of Nuclear Medicine (AIMN) [and] the International Association of Radiopharmacology (IAR), [and] Section of the Society of...
Background Papillary thyroid carcinoma (PTC) with a BRAFV600E mutation is linked to more aggressive tumor characteristics, as well as a higher likelihood of recurrence and disease-specific mortality. This study aimed to investigate the…
View details →Park JE · 2026 · Korean journal of community nutrition
Objectives This study aimed to evaluate the relationship between oxidative balance score (OBS), a metric indicating an individual's oxidative balance status, and the number of teeth in a sample of Korean adults. Methods This…
View details →Hacıvelioğlu D, Turan Tercan A, Tuna Oran N · 2026 · BMC public health
This study examined xenophobia and empathic tendency among 724 midwifery students from different regions of Turkey. Data were collected online using the Student Information Form, the Empathic Tendency Scale, and the Xenophobia Scale, and…
View details →Skowron AT, Childers K, Rose CM et al. · 2026 · The Prostate
Purpose Germline genetic testing in patients with advanced prostate cancer (PCa) is underutilized and hypothesized to be impacted by socioeconomic and demographic factors. This single institution, retrospective study assessed the…
View details →Pisanu C, Squassina A, Perera-Bel J et al. · 2026 · Medicina (Kaunas, Lithuania)
Background and Objectives : Treatment-resistant depression (TRD) is a major clinical challenge in the management of major depressive disorder (MDD). While pharmacogenetics has been suggested to be clinically useful in guiding…
View details →Madsen TE, Raker CA, Pavlovic JM et al. · 2026 · Neurology
Background and objectives Migraine is a known risk factor for stroke in women of reproductive age, although its relationship with stroke among postmenopausal women remains unclear. We assessed the association between migraine history and…
View details →Healey J, Singh M, Richards C et al. · 2026 · BMC medicine
Background Among women in the UK, over 186,000 new cancer diagnoses and around 78,000 cancer deaths occurred annually from 2017 to 2019. Evidence suggests that pregnancy complications are linked to mortality and morbidity risks in later…
View details →Laowong O, Sonsuwan N, Chaiworawitkul M · 2026 · Sleep & breathing = Schlaf & Atmung
PURPOSE: This study investigated anatomical factors associated with obstructive sleep apnea (OSA) in children with unilateral cleft lip and palate (UCLP), focusing on tongue, airway, and hyoid height, using cone-beam computed tomography…
View details →Anees R, Chaudhary MAG, Fatima SK · 2026 · Scientific reports
Facial aesthetics depends on the harmony between facial features and dental morphology, specifically the link between face shape and maxillary central incisor form. Classical theories propose that tooth form corresponds to face outline;…
View details →Alibrahim T, Johnston Y · 2026 · Journal of gerontological nursing
Purpose To examine fall-related medications and fall risk as predictors of fall-related hospitalizations among a cohort of community-dwelling older adults in the southern tier of New York State. Method Participants comprised 8,499 patients…
View details →Pande S, Dakhore S, Arora D et al. · 2026 · Cureus
Background Breast cancer is the most common malignancy among women worldwide and remains a leading cause of cancer-related mortality. In India, delayed presentation and limited access to organised screening programmes contribute to poorer…
View details →Vilsmeier J, Büchele G, Rehm M et al. · 2026 · BMC medical research methodology
Background In the EvaCoM project, a retrospective cohort study of Germany-wide health insurance data of 29607 geriatric patients with fractures, the use of different time scales led to contradicting estimates in the Cox proportional…
View details →Davis AE, Su Y, Dallas R et al. · 2026 · Emerging microbes & infections
Human astroviruses are a common cause of viral gastroenteritis and are often underdiagnosed. While infections are typically mild or asymptomatic in immunocompetent hosts, astrovirus can cause prolonged and severe disease in…
View details →Mittal A, Malhotra K, Panwar V et al. · 2026 · Urology research & practice
Objective: This retrospective cross-sectional analytical study evaluated the clinicopathological associations of programmed death ligand 1 (PD-L1) and human epidermal growth factor receptor 2 (HER2/neu) expression in 250 patients with…
View details →Qiao X, Wang Y, Tian Z et al. · 2026 · Frontiers in psychiatry
Aim To explore the symptom distress and quality of life status of patients with Chronic Kidney Disease (CKD) Stage 5 undergoing hemodialysis in China, and their correlation. Methods The Dialysis Symptom Index (DSI) and the Kidney Disease…
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