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WASTE Journal

Browse the failure-mode index

12,263 real negative results, null findings, and replication failures in Medicine. Search the index →

WASTE indexes published research — it does not host or republish full papers. Each entry is a metadata record compiled from open scholarly databases; the abstract is shown in full only where the paper is openly licensed, otherwise a short excerpt under fair use. Classifications are automated and approximate.

Negative / Null Result ReportMedicine

Comparison of decentration, tilt, and dynamic stability between retropupillary iris claw and scleral fixated intraocular lenses with flanged haptics.

Zeilinger J, Regitnig P, Kronschläger M et al. · 2026 · Journal of cataract and refractive surgery

Purpose To compare decentration, tilt, and dynamic stability ("wobble") between retropupillary fixated iris claw intraocular lenses (IOL) and double needle flanged scleral fixated technique. Setting Vienna Institute for Research in Ocular…

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Negative / Null Result ReportOpen accessMedicine

Alfentanil May Reduce Early Postoperative Nausea and Vomiting in Moderate-to-High Risk Patients Undergoing Gastrointestinal Endoscopy: A Prospective Double-Blind Randomized Study.

Gu XY, Cao JF, Zhang XY et al. · 2026 · Drug design, development and therapy

Objective This trial aimed to compare the effects of alfentanil and sufentanil on postoperative nausea and vomiting (PONV) in patients at moderate-to-high risk undergoing sedated gastrointestinal endoscopy. Methods Two hundred and eighteen…

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Negative / Null Result ReportOpen accessMedicine

Morphometrıc evaluatıon of patıents wıth mandıbular hypomobılıty due to coronoıd process hyperplasıa usıng cone beam computed tomography.

Kurt Akgül Ş, Boylu ÖF · 2026 · Surgical and radiologic anatomy : SRA

PURPOSE: Mandibular hypomobility is a condition in which the jaw joint is restricted due to various causes, including temporomandibular joint disorders (TMD), ankylosis, head and neck infections and tumors, coronoid processes hyperplasia…

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Negative / Null Result ReportOpen accessMedicine

Evaluation of multiple freeze-thaw cycles on growth factor and cytokine stability in canine platelet lysate: PDGF, TGF-<i>β</i>, and TNF-<i>α</i> preservation across cycles.

Sumner SM, Naskou MC · 2026 · Frontiers in veterinary science

Introduction Platelet-rich plasma (PRP) and platelet lysate (PL) are biologically active products used in regenerative medicine because of their high concentrations of growth factors, cytokines, and other bioactive molecules that promote…

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Negative / Null Result ReportMedicine

Observation on the clinical effects of four kinds of root canal filling materials in the treatment of chronic periapical periodontitis.

Wang K, Chen Y, Fu H et al. · 2026 · American journal of translational research

Objective To compare the clinical efficacy of four root canal filling materials for the treatment of chronic periapical periodontitis. Methods The clinical data of 200 patients with chronic periapical periodontitis from January 2023 to…

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Negative / Null Result ReportMedicine

Residual gastric content after holding of glucagon-like peptide-1 receptor agonists before elective surgery: a cross-sectional study - the RESIDUAL study.

Boudreau C, Couture M, Rousseau-Saine N et al. · 2026 · BMC anesthesiology

Introduction Glucagon-like peptide-1 receptor agonists (GLP-1 RA) are now increasingly used for glycemic control in type 2 diabetes mellitus as well as for weight loss. Their effect on gastric emptying may increase the risk of aspiration…

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Negative / Null Result ReportMedicine

Desflurane versus sevoflurane and postoperative inflammatory biomarkers in older adults undergoing minor- to moderate-risk noncardiac surgery.

Adamowitsch N, Reiterer C, Fleischmann E et al. · 2026 · Scientific reports

Volatile anesthetics modulate inflammatory responses, but it remains unclear whether desflurane and sevoflurane differ in their effects on postoperative inflammation. We evaluated in this secondary analysis of a prospective randomized…

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Negative / Null Result ReportOpen accessMedicine

Maternal vaginal colonization screening for term singleton pregnancy: comparative evaluation of metagenomic next-generation sequencing (mNGS) versus real-time quantitative PCR (qPCR).

Zhang J, Liang J, Lv F et al. · 2026 · Practical laboratory medicine

Objective To investigate the distribution characteristics of potential high-risk pathogens for early-onset neonatal infection in maternal vaginal secretions, and to perform a head-to-head comparative evaluation of detection performance for…

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Negative / Null Result ReportMedicine

Striving for trueness: Effect of face scanning on implant planning and interim prosthesis in implant supported prosthesis; A parallel randomized blinded clinical trial.

Abd Allah DAE, Abdelfattah AM, Nawar NH et al. · 2026 · The Journal of prosthetic dentistry

Statement of problem The effect of integrating facial scans into digital planning on the accuracy of placement of dental implants and the preplanned interim prosthesis in maxillary complete arch implant rehabilitations has not been clearly…

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Negative / Null Result ReportOpen accessMedicine

Effectiveness of physio-cognitive dual-task training on improving global cognition, health-related quality of life, and physical outcomes among older adults with neurocognitive disorders: an umbrella review.

Chern CWJ, Cheng LJ, Chiang GSW et al. · 2026 · Age and ageing

Background Physio-cognitive dual-task training (PCDT), combining physical and cognitive tasks, is a promising approach. However, clarity regarding its effectiveness and evidence credibility remains limited. Objective To evaluate PCDT…

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Negative / Null Result ReportOpen accessMedicine

Medical students perceptions of spiritual care.

Prihanti GS, Firmansyah FH · 2026 · Frontiers in medicine

Introduction This study aimed to assess medical students' perceptions of spiritual care using a culturally adapted Muslim-context version of the Spirituality and Spiritual Care Rating Scale (SSCRS). Methods A cross-sectional study was…

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Negative / Null Result ReportMedicine

The Mediating Role of Eudaimonic Well-Being in the Effect of Perceived Poverty on Quality of Life in the Elderly.

Aydin MA, Aydoğdu NG, Kizilarslan V et al. · 2026 · Psychogeriatrics : the official journal of the Japanese Psychogeriatric Society

Background This study was conducted to examine the mediating role of eudaimonic well-being in the effect of perceived poverty on quality of life in the elderly. Methods This descriptive cross-sectional study was conducted with 523 elderly…

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Negative / Null Result ReportOpen accessMedicine

Arbuscular mycorrhizal symbiosis enhances the cadmium stress tolerance of Medicago sativa in association with regulation of the aminolevulinic acid pathway.

Li Y, Wang Z, Xu T et al. · 2026 · BMC plant biology

Arbuscular mycorrhizal (AM) fungi can effectively enhance the photosynthesis and antioxidant capacity of plants under cadmium stress; however, the underlying regulatory mechanisms remain poorly understood. This study focuses on the…

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Negative / Null Result ReportOpen accessMedicine

Methane mitigation, nutritional evaluation, and in vitro degradation kinetics of diets based on tropical grass haylage treated with xylanase.

Duarte ABA, Dias-Silva TP, Viana WCC et al. · 2026 · Tropical animal health and production

The aim of this study was to evaluate the effect of xylanase addition (1.8 g/kg dry matter [DM]) to tropical grass haylage used in total mixed rations (TMR) on in vitro organic matter degradability, ruminal fermentation kinetics, and…

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