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Browse the failure-mode index

12,263 real negative results, null findings, and replication failures in Medicine. Search the index →

WASTE indexes published research — it does not host or republish full papers. Each entry is a metadata record compiled from open scholarly databases; the abstract is shown in full only where the paper is openly licensed, otherwise a short excerpt under fair use. Classifications are automated and approximate.

Failed Experiment ReportOpen accessMedicine

The Assessment of the Effect of Gaze Direction Instruction on the Stabilisation During Artistic Gymnastic Landing.

Pavlasová K, Bizovská L, Rupčík L et al. · 2026 · European journal of sport science

The aim of this study was to assess the effect of gaze direction instruction on postural stabilisation and muscle activity during landings after various motor tasks in artistic gymnastics. Eighteen female gymnasts (aged 14.0 ± 2.7 years)…

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Negative / Null Result ReportMedicine

The tipping point: Friction and thigh length influence imminent falls from a tilting ski lift chair.

Talhelm J, Srivastava S, Ostrander J et al. · 2026 · Proceedings of the Institution of Mechanical Engineers. Part H, Journal of engineering in medicine

Falls by subjects riding a ski lift while in transit are rare but can cause significant injury. Falls can occur at variable heights and can occur to small children to adults of both genders. The current study was designed to investigate…

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Negative / Null Result ReportOpen accessMedicine

The Geographical Variation of Colour Change in the Arabian Killifish (<i>Aphaniops dispar</i> Sensu Lato) From Freshwater and Marine Ecosystems.

Alfakih A, Nadeau NJ, Watt PJ · 2026 · Ecology and evolution

Widely distributed animals may exhibit substantial plastic physiological, morphological and behavioural responses to environmental changes. One such extraordinary form of plasticity is colour change, which varies substantially among most…

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Negative / Null Result ReportMedicine

Visual-Spatial Influences on Vocal Intensity: Effects of Speaker-to-Listener Distance and Room Size in Immersive Virtual Reality.

Daşdöğen Ü, Hitchcock J, Ahn S et al. · 2026 · Journal of speech, language, and hearing research : JSLHR

Objectives The aim of this study was to investigate the effects of speaker-to-listener distance versus room size on individuals' voice perception and production using immersive virtual reality (IVR). Method Fifteen vocally healthy…

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Negative / Null Result ReportOpen accessMedicine

Temporal shift in task factor influence across the stretch reflex.

Torell F, Rohlén R, Dimitriou M · 2026 · PloS one

Mechanical perturbations applied to the arm can elicit reflexive actions. These rapid corrective responses include the stretch reflex, which consists of different components: the short-latency reflex (SLR) and the early and late…

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Negative / Null Result ReportOpen accessMedicine

Up to 30 years of clinical performance of double-crown-retained removable dental prostheses with spark-eroded friction pins placed in a general dental practice.

Zierden K, Werdecker S, Wöstmann B et al. · 2026 · Clinical oral investigations

Purpose The purpose of this retrospective cohort study was to investigate the clinical performance and longevity of double-crown-retained removable-dental-prostheses (DCR-RDP) with spark-eroded friction pins inserted in a general dental…

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Negative / Null Result ReportOpen accessMedicine

Effects of maternal dental anxiety on the time of first dental visit and dental caries status of children.

Mohammadpour N, Shirdel M, Hekmatfar S · 2026 · Journal of education and health promotion

Background This study aimed to assess the effects of maternal dental anxiety on the time of first dental visit and dental caries status of children. Materials and methods This cross-sectional study was conducted on 220 children between 3…

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Negative / Null Result ReportMedicine

The effect of the liquid motion bubbler timer soothing sensory toy on children's fear and anxiety levels during blood sampling: a randomized clinical trial.

Sariali̇oğlu A, Oluç T · 2026 · BMC psychology

Background Blood sampling is one of the invasive procedures in a hospital setting that can cause fear, anxiety, and stress in children. Aim The study aimed to determine the effect of the Liquid Motion Bubbler Timer Soothing Sensory Toy on…

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Negative / Null Result ReportOpen accessMedicine

An improved translational approach to studying persistence-strengthening effects of differential reinforcement of alternative behavior.

Layton KL, Edwards TL, Foster TM · 2026 · Journal of the experimental analysis of behavior

Translational research investigating traditional differential reinforcement of alternative behavior (DRA) suggests that such procedures increase the persistence of target behavior relative to when the alternative behavior is first…

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Failed Experiment ReportOpen accessMedicine

Do Forms of Silicon Other than Orthosilicic Acid, Application Date and Dose Have a Beneficial Effect on Sugar Beet Yield?

Artyszak A, Gozdowski D, Litwińczuk-Bis M · 2026 · Plants (Basel, Switzerland)

In 2017-2019, in a field experiment in Sahryń, Poland (50°40'42″ N, 23°47'35″ E), the effect of foliar application of various forms of silicon (calcium silicate-CS, sodium metasilicate-SM, and micronized silica-MS) and the timing of their…

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Negative / Null Result ReportOpen accessMedicine

Relationship Between Pulmonary Thromboembolism, its Mortality and Seasonal, Meteorological Factors

Seda Beyhan Sağmen, Sevda Cömert, Nesrin Kıral et al. · 2019 · Southern Clinics of Istanbul Eurasia

INTRODUCTION[|]Seasonal and weather changes may affect the development of pulmonary embolism. The effects of seasonal and meteorological factors on mortality are controversial. We aimed to investigate the effects of seasons and meteorological data on patients with a low and high pulmonary embolism severity index and those with 30-day mortality. [¤]METHODS[|]Pulmonary embolism cases were included in our study. Daily pressure, humidity, temperature, and wind values were taken from the general online information by the Directorate of Meteorology. All cases were divided into the low-risk and high-

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Negative / Null Result ReportOpen accessMedicine

Low-dose oral pregabalin is not effective enough to control the acute post-thoracotomy pain

Swati Dogra , Altaf Hussain Mir , Suhail Sidiq et al. · 2025 · Asian Journal of Medical Sciences

Background: Acute post-thoracotomy pain (APTP) is severe and can lead to various respiratory complications if left untreated. Epidural (Ep) analgesia is the gold standard for APTP relief. Aims and Objectives: The aims and objectives of this study were to study the impact of low-dose oral pregabalin 75 mg on APTP. Materials and Methods: 100 patients were randomized into two groups (Group P and C). The Group P, study group received pregabalin 75 mg per oral preoperatively and for 2 days postoperatively. Group C received no medication. All the patients received thoracic Ep as a standard practice.

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Negative / Null Result ReportOpen accessMedicine

Clinical outcomes in low risk coronary artery disease patients treated with different limus-based drug-eluting stents--a nationwide retrospective cohort study using insurance claims database.

Chao-Lun Lai, Ching-Fen Wu, Raymond Nien-Chen Kuo et al. · 2015 · PLoS ONE

The clinical outcomes of different limus-based drug-eluting stents (DES) in a real-world setting have not been well defined. The aim of this study was to investigate the clinical outcomes of three different limus-based DES, namely sirolimus-eluting stent (SES), Endeavor zotarolimus-eluting stent (E-ZES) and everolimus-eluting stent (EES), using a national insurance claims database. We identified all patients who received implantation of single SES, E-ZES or EES between January 1, 2007 and December 31, 2009 from the National Health Insurance claims database, Taiwan. Follow-up was through Decemb

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Negative / Null Result ReportOpen accessMedicine

Obesity and Dyslipidemia

Feingold KR · 2000

Abnormalities in lipid metabolism are very commonly observed in patients who are obese. Approximately 60-70% of patients with obesity are dyslipidemic. The lipid abnormalities in patients who are obese include elevated serum TG, VLDL,…

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Negative / Null Result ReportOpen accessMedicine

Obturator or "lateral" bypass in the management of infected vascular prostheses at the groin

Davidović Lazar B., Kuzmanović Ilija B., Kostić Dušan M. et al. · 2002 · Srpski Arhiv za Celokupno Lekarstvo

The infection of the previously implanted vascular graft at the groin, is associated with great mortality and morbidity rate [1]. The authors present a retrospective study in which they analyzed management of infected vascular prostheses at the groin, using obturator bypass in 26 cases, and "lateral" bypass in 15 cases. The indications for obturator bypass reconstructions included: 20 infections of aorto-femoral grafts, two infected pse udoaneurysms in the groin after RTA of the superficial femoral artery, and 4 infections of iliac-femoral grafts. The indications for lateral bypass reconstruct

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